Tissue Doppler echocardiography predicts long-term cardiovascular mortality: the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) legacy 20-year follow-up study by Simon Thom, Alice Stanton, Jamil Mayet, Amit Kaura, Darrel Francis, Anoop SV Shah, Andrew Sharp, Alun D Hughes, Neil R Poulter, Anenta Ratneswaren, Tong Wu, Somayeh Rostamian, Devan Wasan, PS Sever

“…Background Left ventricular diastolic function as assessed by tissue Doppler echocardiography predicts cardiovascular event rates at 4 years of follow-up in patients with hypertension. Our aim was to evaluate whether this extends to predicting cardiovascular mortality after 20 years of follow-up.Methods Conventional (E) and tissue Doppler (e′) echocardiography was performed on hypertensive participants in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) with long-term follow-up ascertained via linkage to the Office of National Statistics. …”
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Inflammatory Cytokine Profile Associated with Metabolic Syndrome in Adult Patients with Type 1 Diabetes by Aldo Ferreira-Hermosillo, Mario Molina-Ayala, Claudia Ramírez-Rentería, Guadalupe Vargas, Baldomero Gonzalez, Armando Isibasi, Irma Archundia-Riveros, Victoria Mendoza

“…Forty-four percent fulfilled the metabolic syndrome criteria (n=61), 54% had central obesity, 30% had hypertriglyceridemia, 29% had hypoalphalipoproteinemia, and 19% had hypertension. We observed that resistin concentrations were higher in patients with MS. …”
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Prolonged pain-to-balloon time still impairs midterm left ventricular function following STEMI by Dominik Felbel, Sabrina Fackler, Rachel Michalke, Michael Paukovitsch, Matthias Gröger, Mirjam Keßler, Nicoleta Nita, Yannick Teumer, Leonhard Schneider, Armin Imhof, Dominik Buckert, Wolfgang Rottbauer, Sinisa Markovic

“…Mean age was 63 ± 12 years, 75% were male, 14% had diabetes, 72% had arterial hypertension, and 56% had history of smoking. LVEF was reduced in 94% of patients at admission, 69% at discharge, and remained reduced in 45% at the 1-year follow-up. …”
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Prolonged ICU Stay in Severe and Critically-Ill COVID-19 Patients Who Received Convalescent Plasma Therapy by Bambang Pujo Semedi, Nadya Noor Ramadhania, Betty Agustina Tambunan, Siprianus Ugroseno Yudho Bintoro, Soedarsono Soedarsono, Cita Rosita Sigit Prakoeswa

“…ICU LoS was longer in patients, who had prior history of hypertension (aOR = 2.14; 95% CI (1.05, 4.35); p=0.036) and received convalescent plasma (aOR = 3.88; 95% CI (1.77, 8.05); p<0.001). …”
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Pregnancy Complications and Outcomes in Obese Women with Gestational Diabetes by Gitana Ramonienė, Laura Malakauskienė, Eglė Savukynė, Laima Maleckienė, Greta Gruzdaitė

“…Women with pre-pregnancy obesity had a higher incidence of primary hypertension (<i>p</i> < 0.001), hypertensive disorders in pregnancy (<i>p</i> < 0.001), gestational cholestasis (<i>p</i> = 0.002), polyhydramnios (<i>p</i> < 0.001), induced labour (<i>p</i> < 0.001), and caesarean section (<i>p</i> = 0.015), with emergency caesarean sections being more frequent than planned caesarean sections (<i>p</i> = 0.011) compared to normal-weight women with GDM. …”
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Recurrent syncope after hysteroscopy finally diagnosed as cerebral venous sinus thrombosis: a case report by Yongqing Zhang, MD, Hongxing Ye, MD, Danqing Chen, MD, PhD, Guohui Yan, MD, Zhanfu Li, MD, Qianhui Xie, MD, Guodong Shan, MD, Zhaoxia Liang, MD, PhD

“…Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular condition that causes obstruction of venous blood flow or cerebrospinal fluid circulation, leading to intracranial hypertension symptoms such as syncope and vomiting. Transurethral Resection of the Prostate (TURP) syndrome, a complication of hysteroscopic surgery, can also present with cerebral edema and symptoms similar to CVST, making differentiation challenging. …”
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Metabolic dysfunction-associated fatty liver disease and risk of nephrolithiasis: a sizeable cross-sectional study by Shengqi Zheng, Tianchi Hua, Guicao Yin, Wei Zhang, Xiaoxiang Wang, Lezhong Qi, Xiayong Jing, Qibing Fan, Xiaoping Yu, Yifan Li

“…Subgroup analyses indicated that, even after accounting for various factors such as age, diabetes, hypertension, obesity, lipid profiles, and renal function, the positive association between MAFLD and an increased risk of nephrolithiasis remained consistent. …”
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Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis by Işıl Peker, Hacer Eroğlu İçli, Belgin Mutluay, Burcu Yüksel, Zeynep Özdemir, Mesrure Köseoğlu, Aysu Şen, Dilek Ataklı, Aysun Soysal, Musa Öztürk

“…<b>Methods:</b> Forty-two patients with MS were enrolled, along with 22 controls, 12 of the controls were idiopathic intracranial hypertension (IIH) patients, and 10 of the controls were other neurologic diseases (OND). …”
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Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism by Xurong Mai, Mitsuhiro Kometani, Toshiaki Kato, Ko Aiga, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Koshiro Nishimoto, Kazuyoshi Hosomichi, Atsushi Watanabe, Yuko Noda, Yoshiyu Takeda, Takashi Yoneda

“…Pheochromocytoma is a rare form of adrenal hypertension. This study aimed to investigate the clinical characteristics and associated genetic mutations in patients with pheochromocytoma and primary aldosteronism. …”
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The association between monocyte to high-density lipoprotein cholesterol ratio and chronic kidney disease in a Chinese adult population: a cross-sectional study by Lingling Xu, Dongling Li, Zongwei Song, Jin Liu, Yang Zhou, Junwei Yang, Ping Wen

“…Similar conclusions were confirmed in subgroup analysis stratified by gender, age, BMI, central obesity, hypertension, and diabetes mellitus, after justification for confounding factors.Conclusion Elevated MHR level was independently associated with the presence of CKD, suggesting that it might serve as a useful clinical tool for risk stratification, offering valuable insights to inform preventive and therapeutic approaches for clinicians in their routine medical practice.…”
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Depression Paradox in Cardiovascular Outcomes of Adult Patients with Obstructive Sleep Apnea: Insights from 2 Million Nationwide Hospitalizations by Rupak Desai, Sashwath Srikanth, Shaylika Chauhan, Zainab Gandhi, Warda Shahnawaz, Aleen Rahman, Bisharah Rizvi, Akhil Jain

“…OSA+D+ cohort had a higher prevalence of hypertension, diabetes, hyperlipidemia, congestive heart failure, anemia, smoking, substance abuse, prior myocardial infarction (MI), transient ischemic attack (TIA), TIA/stroke, and venous thromboembolism than the OSA+D- group (all P < 0.001). …”
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Patients with Age-related Macular Degeneration Have Increased Susceptibility to Valvular Heart Disease by Natan Lishinsky-Fischer, Itay Chowers, MD, PhD, Yahel Shwartz, MSc, Jaime Levy, MD

“…Aortic valve stenosis is the third most common cardiovascular disease in the Western world, after hypertension and coronary artery disease. Recent studies have reported an association between VHD and the presence of subretinal drusenoid deposits (SDDs), a distinct manifestation of age-related macular degeneration (AMD). …”
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Association of weight-adjusted-waist index with type 2 diabetes mellitus in Chinese urban adults: a cross-sectional study by Qingzheng Wu, Bing Li, Yuepeng Wang, Yuepeng Wang, Yue Zhang, Qian Wang, Binqi Li, Binqi Li, Wei Jing, Jing Yang, Yiming Mu

“…After adjusting for all factors with the exception of the stratified variable, this association held true in age, sex, BMI, hypertension, and hyperlipidemia subgroup and was especially pronounced in those aged &lt;60 years, BMI ≥24 kg/m2, and males, with interactions between WWI and age, sex, and BMI (P for interaction &lt;0.05).ConclusionWWI was positively associated with T2DM in Chinese urban adults, especially in young and middle-aged males with BMI ≥24 kg/m2.…”
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Geriatric nutritional risk index as a predictor of 30-day and 365-day mortality in patients with acute myocardial infarction: a retrospective cohort study using the MIMIC-IV databa... by Xiaolong Zheng, Xiaolong Zheng, Xin Zheng, Xin Zheng, Changgui Zhang, Minghua Liu

“…Subgroup analyses were conducted based on gender, hypertension, diabetes, stroke, hyperlipidemia, chronic obstructive pulmonary disease, and age. …”
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Expanded screening for Fabry disease in patients with chronic kidney disease not on dialysis: a multicenter Italian experience by Yuri Battaglia, Federica Baciga, Meilad Shakkour, Savio Russo, Giulia Carnicella, Michela Erlati, Gemma Sartori, Giulia Tronconi, Renzo Mignani, Federico Pieruzzi, Paolo Colomba, Laura Scichilone, Michele Andreucci, Concetto Sessa, Giovanni Duro

“…FD screening should be expanded to include NDD-CKD patients with known causes of CKD, such as hypertension and diabetes mellitus, and genetic testing should be routinely used for female patients.…”
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Safety and efficacy of intravenous thrombolysis: a systematic review and meta-analysis of 93,057 minor stroke patients by Mostafa Hossam El Din Moawad, Talal Salem, Anas Alaaeldin, Youssef Elaraby, Peter D. Awad, Amr Ahmed Khalifa, Ahmed El Naggar, Khaled Ashraf Mohamed, Mohamed Elhalal, Mostafa Badr, Ramy Abdelnaby

“…Most of the included patients had comorbidities such as hypertension, diabetes, previous stroke, smoking, atrial fibrillation, and hyperlipidemia. …”
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Clinical role of endothelial dysfunction and hemostasis gene allelic variants in hepatitis C virus-associated cryoglobulinemia by M. V. Sokolova, Ye. Ye. Starostina, T. N. Krasnova, L. M. Samokhodskaya, T. P. Rozina, V. G. Avdeyev, M. G. Artemova, Ye. B. Yarovaya, N. A. Mukhin

“…The T allele of NOS3 894 G/T gene was found in patients with renal disease significantly less frequently (15% vs 45.5%; р=0.035) as well as in patients with systemic hypertension (30% and 72.7%; р=0.086). Conclusions. Carriage of GT genotype of NOS3 894 G/T gene and CC genotype of ITGB3 1565 T/C gene is associated with high risk of CryoVas development. …”
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High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation by Dariusz Szukiewicz, Michal Pyzlak, Grzegorz Szewczyk, Aleksandra Stangret, Seweryn Trojanowski, Michal Bachanek, Wojciech Braksator, Jaroslaw Wejman

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Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance by Bogdan Batko, Slawomir Jeka, Piotr Wiland, Agnieszka Zielińska, Maria Stopińska-Polaszewska, Marcin Stajszczyk, Magdalena Kosydar-Piechna, Mary Jane Cadatal, Jose L. Rivas

“…Results Of 4362 patients (Poland, N = 759; North America, N = 1243; Other countries, N = 2360), more patients from North America versus Poland/Other countries had CV risk factors such as body mass index ≥ 30 kg/m2 and history of diabetes/hypertension; however, more patients from Poland versus other regions were ever smokers and more patients from Poland/North America versus Other countries had history of coronary artery disease. …”
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The impact of energy drinks on health of children and young adults - review of latest research by Klaudia Kożuchowska, Dawid Pilarz, Marcelina Szewczyk, Maria Morawska, Aleksandra Tomczyk, Julia Ufnal, Dominika Lewandowska, Dominika Rosińska-Lewandoska, Klaudia Drewko, Kinga Jarosz

“…Consuming energy drinks leads to hypertension and increased cardiovascular risk. In addition, energy drinks can cause sleep disorders, anxiety and hyperactivity. …”
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