Crosstalk between MicroRNAs and Peroxisome Proliferator-Activated Receptors and Their Emerging Regulatory Roles in Cardiovascular Pathophysiology by Yin-Feng Zhang, Hai-Ming Xu, Fei Yu, Man Wang, Meng-Yang Li, Tao Xu, Yan-Yan Gao, Jian-Xun Wang, Pei-Feng Li

“…PPARs are inhibited by miRNAs at posttranscriptional mechanisms in the progress of pulmonary hypertension and vascular dysfunction involving cell proliferation/apoptosis, communication, and normal function of endothelial cells and vascular smooth muscle cells. …”
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Association between frailty index and mortality in depressed patients: results from NHANES 2005–2018 by Xiaoqiang Liu, Yubin Wang, Yingxuan Huang, Chanchan Lin, Boming Xu, Yilin Zeng, Peizhong Chen, Xiaobo Liu, Yisen Huang

“…These results were consistent across analyses stratified by age, gender, race, BMI, hypertension, and diabetes. This study suggests that the frailty index is positively associated with all-cause and cause-specific mortality in patients with depression. …”
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Kidney damage on fertility and pregnancy: A Mendelian randomization. by Jin Ren, Qiuyan Huang, Xiaowei Lie, Xingli Tong, Qi Yao, Ge Zhou

“…Moreover, increased urinary albumin-to-creatinine ratio (UACR) was regarded as a potential risk factor for pre-eclampsia (OR = 1.936; 95% CI 1.065 to 3.517) and gestational hypertension (OR = 1.700; 95% CI 1.002 to 2.886). Fertility assessment: The results indicated that eGFR and UACR had a suggestive causal relationship with the anti-Müllerian hormone level (eGFR beta: 1.004; UACR beta: 0.405).…”
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Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study by Marian Kiel, Stephanie D. Grabitz, Susanne Hopf, Thomas Koeck, Philipp S. Wild, Irene Schmidtmann, Karl J. Lackner, Thomas Münzel, Manfred E. Beutel, Norbert Pfeiffer, Alexander K. Schuster

“…A smaller pupil was associated with older age, hyperopic refractive error, previous cataract surgery, diabetes, obesity, and ACE inhibitor intake, whereas wider pupil was associated with female gender, arterial hypertension, intake of tricyclic antidepressants, and intake of SNRI and tetracyclic antidepressants. …”
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Chronic non-communicable diseases in patients and families with retinitis pigmentosa by Raisa Hernández Baguer, Raisa Ivis Beltràn Saìnz, Asunciòn Fortunata Rodrìguez Morris, Dagmara Magdalena Cordero Ruiz, Loida Mevis Savòn George, Bàrbara Cid Vàzquez

“…<br /><strong>Results:</strong> of 145 people studied (74 patients with retinitis pigmentosa and 71 relatives), 138 (95.1%) had non-communicable chronic diseases, among which arterial hypertension (29.7%), diabetes mellitus (21 0.0%) and the association of both (13.0%). …”
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Regional risk factors associated with adverse outcomes of COVID-19 infection among the older adult: A systematic review and meta-analysis by Olunike Rebecca Abodunrin, Mobolaji Timothy Olagunju, Xinyi Huang, Jianming Wang, Zhibin Hu, Chong Shen

“…Key factors include old age (above 65 years), male gender, symptoms such as fever and dyspnea, and comorbidities like dementia, chronic obstructive pulmonary disease (COPD), chronic heart disease, hypertension, chronic kidney disease, and malnutrition. …”
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Bioinformatics and System Biological Approaches for the Identification of Genetic Risk Factors in the Progression of Cardiovascular Disease by Joy Dip Barua, Shudeb Babu Sen Omit, Humayan Kabir Rana, Nitun Kumar Podder, Utpala Nanda Chowdhury, Md Habibur Rahman

“…We observed that the number of 32, 17, 53, 70, and 89 differentially expressed genes (DEGs) is overlapped between CVD and its risk factors of hypertension (HTN), type 2 diabetes (T2D), hypercholesterolemia (HCL), obesity, and aging, respectively. …”
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The Clinical Significance of High Antimicrobial Resistance in Community-Acquired Urinary Tract Infections by Maria G. Zavala-Cerna, Midrori Segura-Cobos, Ricardo Gonzalez, Isidro G. Zavala-Trujillo, Silvia F. Navarro-Perez, Jose A. Rueda-Cruz, Fernando A. Satoscoy-Tovar

“…The only clinical variable with significant association to ESBL producers was the presence of comorbidities: hypertension and type 2 diabetes mellitus with an OR (95%CI) of 2.51.3−4.9p<0.01 and 2.81.2−6.7p<0.05, respectively. …”
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Factors associated with early-onset androgenetic alopecia: A scoping review. by Li-Ping Liu, Mary Adumo Wariboko, Xiao Hu, Zi-Han Wang, Qian Wu, Yu-Mei Li

“…Men with early-onset AGA may have reduced treatment efficacy with drug like rosuvastatin, metformin or lisinopril for dyslipidemia, prediabetes, or hypertension. Additionally, young men with AGA tended to suffer from psychological issues such as anxiety and low self-esteem compared to those without hair loss.…”
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Clinical Traits of SARS-CoV-2 Infection by O. Yu. Zolnikova, N. L. Dzhakhaya, N. D. Potskherashvili, K. B. Puzakov, O. Yu. Кiseleva, N. I. Kokina, E. R. Buklis, T. V. Roshchina, I. I. Коmkova

“…The risk of critical SARS-CoV-2 infection increases with elder age (p ≤ 0.001), associates with the male gender and presence of concomitant diseases, such as obesity (p &lt; 0.01), diabetes mellitus (p &lt; 0.001), hypertension (p ≤ 0.001), CHD (p ≤ 0.001) and atrial fibrillation (p &lt;0.05).Conclusion. …”
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Posterior reversible encephalopathy syndrome in a young male with IgA nephropathy and chronic kidney disease: a case report from the Maldives by Rajib Kumar Dey, Gunjan Khadka, Shifa Ishaq, Aishath Zeena Abdul Jaleel, Aminath Shafeenaz Moosa, Saifullah Muslim, Ali Nazeem

“…Abstract Background Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological condition which is commonly associated with chronic kidney disease (CKD), hypertensive encephalopathy, eclampsia, and the use of cytotoxic drugs. …”
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Serum Thyrotropin Is Positively Correlated with the Metabolic Syndrome Components of Obesity and Dyslipidemia in Chinese Adolescents by Jingfan Zhang, Ranhua Jiang, Ling Li, Ping Li, Xue Li, Zinan Wang, Liang Li, Weiping Teng

“…Metabolic syndrome is a medical disorder characterized by obesity, hyperglycemia, dyslipidemia, and hypertension. Thyroid hormone has been shown to affect many metabolic processes. …”
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Current Approach of Functioning Head and Neck Paragangliomas: Case Report of a Young Patient with Multiple Asynchronous Tumors by Alejandro Terrones-Lozano, Alan Hernández-Hernández, Edgar Nathal Vera, Gerardo Yoshiaki Guinto-Nishimura, Jorge Luis Balderrama-Bañares, Claudia Ramírez-Rentería, Judith de la Serna-Soto, Alfredo Adolfo Reza-Albarran, Lesly Portocarrero-Ortiz

“…The usual clinical presentation of functioning PCPG includes paroxistic hypertension, headache, and diaphoresis, sometimes with a suggestive family history in 30–40% of cases. …”
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Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study by Altaf S. Mosad, Ghada A. Elfadil, Alsadig Gassoum, Khanssa M. Elamin, Nazik Elmalaika Obaid Seid Ahmed Husain

“…Multivariate logistic regression analysis showed hypertension, hyperglycemia, BMI, WC, serum TG, ADIPOQ rs2241766 (TG allele), and ADIPOQ rs1501299 (GT allele) had independently predicted the incidence of metabolic syndrome in the Sudanese population. …”
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The evaluation of the predictors of left ventricular systolic function improvement in patients with severe aortic stenosis after aortic valve replacement by N.V. Ponych, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…Group of patients with greater growth of LVEF was characterized by lower body mass index (p = 0.016), greater initial signs of heart failure (p = 0.019), less frequent arterial hypertension. In addition, patients with LVEF growth over 30 % had more pronounced decrease of initial EF, greater end-systolic volume (ESV) index and changes of some indices of diastolic LV function. …”
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Grounded theory assessment of health needs in rural Mississippi Delta region, USA: Implications for health policy and management by Yalanda M. BARNER, Austine U. ONYIA, Russell L. BENNETT, Manoj SHARMA

“…Participants identified hypertension, diabetes, mental health, and cancer as the most prevalent diseases. …”
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Evidence from NHANES 2011–2014: a correlation between the weight-adjusted-waist index and cognitive abilities in the United States by Chan Zhao, Xintian Xu, Chunyan Hao

“…We also executed subgroup analyses and interaction tests based on gender, race, educational background, marital status, diabetes, body mass index, alcohol consumption, hypertension, smoking habits, stroke, depression, and sleep quality to assess whether the relationship between WWI and cognitive function was affected by heterogeneity across different population segments. …”
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Adrenal Insufficiency under Standard Dosage of Glucocorticoid Replacement after Unilateral Adrenalectomy for Cushing’s Syndrome by Kentaro Fujii, Kazutoshi Miyashita, Isao Kurihara, Ken Hiratsuka, Seiji Sato, Kenichi Yokota, Sakiko Kobayashi, Hirotaka Shibata, Hiroshi Itoh

“…The patient was a 62-year-old woman who has had hypertension for 5 years and presented with heart failure due to hypertrophic cardiomyopathy. …”
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Effects of Unilateral Nephrectomy on Renal Function in Male Spontaneously Diabetic Torii Fatty Rats: A Novel Obese Type 2 Diabetic Model by Yoshiaki Katsuda, Yusuke Kemmochi, Mimi Maki, Ryuhei Sano, Yasufumi Toriniwa, Yukihito Ishii, Katsuhiro Miyajima, Kochi Kakimoto, Takeshi Ohta

“…Induction of 1/2 Nx in SDT fatty rats led to functional and morphological damage to the remnant kidney and to hypertension, which are considered main characteristics of chronic kidney disease, at a younger age compared with the sham group. …”
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Cardiovascular Risk Assessment: A Comparison of the Framingham, PROCAM, and DAD Equations in HIV-Infected Persons by Max Weyler Nery, Celina Maria Turchi Martelli, Erika Aparecida Silveira, Clarissa Alencar de Sousa, Marianne de Oliveira Falco, Aline de Cássia Oliveira de Castro, Jorge Tannus Esper, Luis Carlos Silva e Souza, Marília Dalva Turchi

“…The participants' mean age was 36.8 years (SD = 10.3), 76.9% were men, and 66.3% were on antiretroviral therapy. 47.8% of the participants had abdominal obesity, 23.1% were current smokers, 20.0% had hypertension, and 2.0% had diabetes. At least one lipid abnormality was detected in 72.8%, and a low HDL-C level was the most common. …”
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