Molecular Modeling Studies of Substituted 2,4,5-Trisubstituted Triazolinones Aryl and Nonaryl Derivatives as Angiotensin II AT1 Receptor Antagonists by Mukesh C. Sharma, D. V. Kohli, Smita Sharma

“…The development of new therapies to treat hypertension and cardiovascular diseases. A series of 2,4,5-trisubstituted triazolinones aryl and nonaryl derivatives were subjected to Group-based QSAR, k-nearest neighbour molecular field analysis, and pharmacophore mapping. …”
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The Relation of Coffee Consumption to Serum Uric Acid in Japanese Men and Women Aged 49–76 Years by Ngoc Minh Pham, Daigo Yoshida, Makiko Morita, Guang Yin, Kengo Toyomura, Keizo Ohnaka, Ryoichi Takayanagi, Suminori Kono

“…Statistical adjustment was made for body mass index, alcohol use, hypertension, diabetes mellitus, and other factors. Results. …”
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Ultrasonography of Optic Nerve Sheath Diameter in Healthy Volunteers by Ariel Sosa Remón, Wilfredo Boch Rodríguez, Dasha María García Arias, Carmen Esther Remón Chávez, Ana Esperanza Jerez Álvarez, Arian Jesús Cuba Naranjo

“…One of the deficiencies stated is the non-existence of a standard value that suggests the limit between normality and intracranial hypertension. <br /><strong>Objective:</strong> determine the diameter of the optic nerve sheath using ultrasound in healthy volunteers. …”
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Hyperbaric Oxygen Therapy in Retinal Arterial Occlusion: Epidemiology, Clinical Approach, and Visual Outcomes by Ana Sofia Lopes, Rita Basto, Susana Henriques, Luísa Colaço, Filomena Costa e Silva, Isabel Prieto, Francisco Guerreiro

“…Results. Arterial hypertension was the most prevalent systemic risk factor (53.8%). …”
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Uncoded chronic kidney disease prevalence in secondary care: a retrospective audit with population health implications by Samantha Dolan, Ajitesh Anand, Philip A. Kalra, Stuart Stewart

“…Conversion of uncoded to coded CKD at discharge was only 6.7%. Hypertension and advanced CKD were significant predictors of coding CKD on discharge in uncoded patients. …”
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The Renal and Liver Complications Development among Patients with Type 2 Diabetes Mellitus in Kirkuk City by Wasan Talib Abed, Walaa Esmael Jassim, Emad Mohamed Rasheed

“…The hospital-based cases- control study was conducted for patients with T2DM patients that attended the diabetic clinics in Kirkuk during the period from March 2021– to August 2021 and were screened for serum conc. of liver function tests (Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST) and Alkaline Phosphatase (ALP)), renal function tests (Creatinine and Urea) especially with (family history of diabetes, & hypertension.  Patients recruited for this study, showed serum urea and creatinine significantly more than that in control, p < .001, while for renal glomerular filtration rates significantly lower than that in control group, p < 001. …”
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Influence of Artificial Sweetener on Human Blood Glucose Concentration by Ilse Skokan, P. Christian Endler, Beatrix Wulkersdorfer, Dieter Magometschnigg, Heinz Spranger

“…In this pilot-study 16 patients were included suffering from adiposity, pre-diabetes and hypertension. In the sense of a cross-over design, three test trials were performed at intervals of several weeks. …”
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Risk Factors for Macro- and Microvascular Complications among Older Adults with Diagnosed Type 2 Diabetes: Findings from The Irish Longitudinal Study on Ageing by Marsha L. Tracey, Sheena M. McHugh, Anthony P. Fitzgerald, Claire M. Buckley, Ronan J. Canavan, Patricia M. Kearney

“…Diabetes diagnosis of 10 or more years, a history of smoking, and a diagnosis of hypertension were associated with an increased risk of microvascular complications. …”
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Smoking as a causative factor in chronic kidney disease: a two-sample Mendelian randomization study by Yue Yang, Zheng Zhang, Hai-tao Lu, Qian-qian Xu, Li Zhuo, Wen-ge Li

“…Additionally, the effect of smoking on CKD was mediated by factors such as body mass index, cardiovascular disease, hypertension, and type 2 diabetes. These findings identify smoking as a contributing factor to CKD and suggest that reducing smoking prevalence could significantly lower the incidence of CKD in the population.…”
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The Guyana Diabetes and Foot Care Project: Improved Diabetic Foot Evaluation Reduces Amputation Rates by Two-Thirds in a Lower Middle Income Country by Julia Lowe, R. Gary Sibbald, Nashwah Y. Taha, Gerald Lebovic, Madan Rambaran, Carlos Martin, Indira Bhoj, Brian Ostrow

“…Phase 2: Regionalization to cover 90% of the Guyanese population and expansion to include improved management of diabetes and hypertension. Fourteen key opinion leaders were educated and 340 health care professionals from 97 facilities trained. …”
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Liver lobes and cirrhosis: Diagnostic insights from lobar ratios by Kriti Pandey, Debabrata Dash, Raj Kumar Koiri

“…Cirrhosis primarily causes portal hypertension which has a varying impact on the four lobes. …”
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Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade by Avantika Chenna, Venu Madhav Konala, Subhasish Bose, Sasmit Roy, Bhaskar Reddy Madhira, Vijay Gayam, Srikanth Naramala, Sreedhar Adapa

“…The renin-angiotensin system plays a very critical role in hypertension, diabetes, and kidney and heart diseases. …”
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Specialized Medical Weight Management Intervention for High-Risk Obesity by Gitanjali Srivastava, Chelsea Paris, Jessica Johnson, Emma Barnes, Brittany L. Cunningham, C. J. Stimson, Kevin D. Niswender, Sabrina J. Poon

“…The prevalence of any obesity-related medical condition was 54.1%; at least a quarter of the patients had either prediabetes or Type 2 diabetes mellitus, approximately a third had hypertension, and over 8% had hyperlipidemia. Mean weight loss from the initial program start date was 6.28% (+/-0.48% standard error of mean [SEM]; 95% confidence interval [CI] 5.34-7.23%). …”
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Genetic proxies for clinical traits are associated with increased risk of severe COVID-19 by N. J. M. Chaddock, S. S. R. Crossfield, M. Pujades-Rodriguez, M. M. Iles, A. W. Morgan

“…In univariate analyses, 17 PRS were associated with increased risk of severe COVID-19 and, of these, four remained associated with COVID-19 outcomes following adjustment for sociodemographic/clinical variables: hypertension PRS (OR = 1.1, 95%CI 1.03–1.18), atrial fibrillation PRS (OR = 1.12, 95%CI 1.03–1.22), peripheral vascular disease PRS (OR = 0.9, 95%CI 0.82–0.99), and Alzheimer’s disease PRS (OR = 1.14, 95%CI 1.05–1.25). …”
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Takotsubo Cardiomyopathy in the Setting of Tension Pneumothorax by Michael Gale, Pablo Loarte, Brooks Mirrer, Thierry Mallet, Louis Salciccioli, Alison Petrie, Ronny Cohen

“…A 78-year-old female presented to the ED with severe shortness of breath, hypertension, and tachycardia. On physical exam, heart sounds (S1 and S2) were regular and wheezing was noticed bilaterally. …”
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Integrated analysis of proteomics and metabolomics in infantile epileptic spasms syndrome by Jun Chen, Xiaoqian Wang, Xueyi Rao, Huan Luo, Yajun Shen, Jing Gan

“…Cerebrospinal fluid samples from 6 IESS patients and 6 control subjects with benign intracranial hypertension were collected and analyzed using metabolomics and proteomics techniques. …”
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Self-management of non-communicable diseases in low- and middle-income countries: A scoping review. by Jason Hearn, Isaac Ssinabulya, Jeremy I Schwartz, Ann R Akiteng, Heather J Ross, Joseph A Cafazzo

“…The selected studies largely focused on the self-management of diabetes (N = 21), hypertension (N = 7) and heart failure (N = 5). Most interventions involved the use of short message service (SMS, N = 17) or phone calls (N = 12), while others incorporated educational sessions (N = 10) or the deployment of medical devices (N = 4). …”
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Normative Values of Peripapillary Retinal Nerve Fiber Layer Thickness in a Middle Eastern Population by Mouna M. Al-Sa’ad, Amjad T. Shatarat, Justin Z. Amarin, Darwish H. Badran

“…The relationship between aging and pRNFL thinning is independent of diabetes mellitus type 2 and systemic hypertension. Both systemic conditions significantly predicted pRNFL changes despite negative fundoscopic findings. …”
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The Polymorphism rs2725220 Is Associated with Hyperuricemia in the Korean Population by Jae Woong Sull, Seung-Ju Yang, Soriul Kim, Sun Ha Jee

“…Elevated serum uric acid levels are associated with a variety of adverse health outcomes, including gout, hypertension, diabetes mellitus, metabolic syndrome, and cardiovascular diseases. …”
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Chlamydial bacteriophage: No Role in Acute Coronary Events? by David M Patrick, Karuna Karunakaran, Adrian R Levy, Kenneth Gin, Valencia Remple, Mei Chong, Heather Abbey, Laura Tarry, Caixia Shen, Robert C Brunham

“…As expected, case subjects were significantly more likely to have hypertension, hypercholesterolemia or diabetes mellitus. …”
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