Serum biochemical profile in case of cardiorenal syndrome in cats with hypertrophic cardiomyopathy by Yu. A. Vatnikov, E. D. Sotnikova, V. I. Kuznetsov, A. A. Razumova, I. V. Shchurov, O. A. Petrukhina, A. A. Rudenko

“…Biochemical tests in animals with feline cardiorenal syndrome verified cytolysis of cardiomyocytes (increased serum activity of lactate dehydrogenase by 2.69 times, creatine phosphokinase by 2.02 times, increased serum concentration of cardiac troponin by 5.20 times as compared to healthy animals), azotemia (increased concentration in serum creatinine by 2.72 times, urea by 2.94 times, symmetric dimethylarginine by 2.60 times and cystatin C by 1.90 times as compared to healthy animals), enhanced ketogenesis, systemic inflammatory process (increased serum concentration of C-reactive protein by 1.55 times as compared to healthy animals), hypercholesterolemia, oxidative stress (decrease in serum activity of superoxide dismutase by 1.63 times, catalase by 4.67 times and glutathione peroxidase by 1.71 times, increase in the concentration of malondialdehyde by 1.79 times, ceruloplasmin by 2.50 times and diene conjugates by 1.85 times as compared to healthy animals), electrolyte imbalance in the form of hyperkalemia, hyponatremia, hyperphosphatemia and hypomagnesemia. …”
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The Result of Timely Therapy for Whipple's Disease: a Clinical Case by S. N. Mekhtiev, O. A. Mekhtieva, E. Yu. Kalinina, V. E. Karev, A. V. Vanyan, O. M. Berko

“…The disease began with articular syndrome followed by diarrhea and manifestations of malabsorption (iron deficiency anemia, hypoalbuminemia, hypercholesterolemia). The diagnosis was established on the basis of morphological changes in biopsy samples of the postbulbar part of the duodenum. …”
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Measuring the Prevalence of Chronic Kidney Disease among Type 2 Diabetes Mellitus Patient in Hospital Jitra: A Population-Based Cohort Study by Norazila Abdul Ghani, Sharifah Nor Faiza Syed Hassan, Rusyidah Zainol Abidin, Zarmisha Zakaria, Fatin Farhana Ahmad Nasir, Ahmad Zulfitri Azmi

“…Hypertension, hypercholesterolemia and heart disease were the most common comorbidities among them; 92.3%, 78.0%, and 23.1%, respectively. …”
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Hypocholesterolemic Activity of Monascus Fermented Product in the Absence of Monacolins with Partial Purification for Functional Food Applications by Zahra Ajdari, Maaruf Abd Ghani, Mohd Khan Ayob, Saadi Bayat, Mazlin Mokhtar, Sahar Abbasiliasi, Anahita Khoramnia, Heshu Sulaiman Rahman, Parvaneh Mehrbod, Daniel Ajdari, Arbakariya B. Ariff

“…Hypercholesterolemia is one of the most common chronic diseases in human. …”
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Saffron's protective role against atherosclerosis-induced cataract progression in New Zealand white rabbits with phytochemical analysis of saffron's extract. by Yasmin Mohd Zainal Abidin Shukri, Iman Nabilah Abd Rahim, Nurul Alimah Abdul Nasir, Che Puteh Osman, Noor Alicezah Mohd Kasim

“…Cataracts are significant causes of blindness, closely linked to prolonged hypercholesterolemia. While saffron has the potential for eye health, its effects on lens lesions remain understudied. …”
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Hypertension and Its Associated Risk Factors in the Kingdom of Saudi Arabia, 2013: A National Survey by Charbel El Bcheraoui, Ziad A. Memish, Marwa Tuffaha, Farah Daoud, Margaret Robinson, Sara Jaber, Sarah Mikhitarian, Mohammad Al Saeedi, Mohammad A. AlMazroa, Ali H. Mokdad, Abdullah A. Al Rabeeah

“…Risk of hypertension increased among men, with age, obesity, diabetes, and hypercholesterolemia. 57.8% of hypertensive Saudis were undiagnosed. …”
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Treatment of Severe Hypercapnic Respiratory Failure Caused by SARS-CoV-2 Lung Injury with ECCO2R Using the Hemolung Respiratory Assist System by Ramiro Saavedra-Romero, Francisco Paz, John M. Litell, Julia Weinkauf, Carina C. Benson, Lisa Tindell, Kari Williams

“…This patient’s multiple comorbid conditions included obesity, hypertension, type 2 diabetes mellitus, and hypercholesterolemia. On her fifth day of admission at the referring hospital, her worsening hypoxemia prompted endotracheal intubation during which she developed pneumothorax. …”
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Epidemiologic features of non-alcoholic fatty liver disease in Russia by O. M. Drapkina, V. T. Ivashkin

“…The major risk factors revealed in NAFLD patients population, were systemic hypertension (69,9%), abdominal obesity (56,2%), hypercholesterolemia (68,8%).Conclusions. Prevalence of NAFLD among adult population of Russia is very high: almost every third patient who was looking for medical attention in polyclinic, has one of NAFLD-related disease entities. …”
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Monoclonal Gammopathy of Undetermined Significance with Amyloid Deposition in the Lung and Non-Amyloid Eosinophilic Deposition in the Brain: A Case Report by Francois Abi-Fadel, Nisarg R. Desai, Gita Vatandoust, Rabih Said, Aaron Gottesman, Terenig Terjanian

“…Past medical history (PMH) included hypertension, hypercholesterolemia, aortic valve replacement (nonmetallic), incomplete heart block controlled by a pacemaker and IgG- IgA type Monoclonal Gammopathy of Undetermined Significance. …”
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Characterization of Metabolically Healthy Obese People and Metabolically Unhealthy Normal-Weight People in a General Population Cohort of the ABCD Study by Silvio Buscemi, Pierfilippo Chiarello, Carola Buscemi, Davide Corleo, Maria Fatima Massenti, Anna Maria Barile, Giuseppe Rosafio, Vincenza Maniaci, Valentina Settipani, Loretta Cosentino, Carla Giordano

“…Participants were classified as normal weight (BMI < 24.9 kg/m2) or overweight-obese (BMI ≥25 kg/m2); they were also classified as MH in the presence of 0-1 among the following conditions: (a) prediabetes/type 2 diabetes, (b) hypertension, (c) hypertriglyceridemia or low HDL cholesterolemia, and (d) hypercholesterolemia. MUH condition was diagnosed if ≥2 of the conditions listed were found. …”
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Prognostic Value of Endothelial Progenitor Cells in Acute Myocardial Infarction Patients by Gongjie Ye, Xiaodan Chen, Yinchao Zhou, Jianqing Zhou, Yongfei Song, Xiaoyong Yang, Lei Yang

“…The study incorporated various variables, including cardiovascular risk factors such as body mass index, hypertension, diabetes, hypercholesterolemia, atherosclerotic burden, and medication history, as well as clinical characteristics such as APACHEⅡscore, central venous-arterial carbon dioxide difference (GAP), homocysteine, creatinine, C-reactive protein, HbAlc, and cardiac index. …”
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Principles of effective out-patient diagnostics of diffuse liver diseases by Komova A. G., M. V. Mayevskaya, V. T. Ivashkin

“…By more strict estimation at multifactorial analysis major risk factors were determined: age 30 to 59 years (p&lt;0,001), intake of alcoholic beverages in harmful dozes (over 16 points of AUDIT questionnaire, p=0,04), hypercholesterolemia (p=0,016). Relative weight of those, requiring etiological and pathogenic treatment after specification of preliminary diagnosis, of patients with abnormal liver tests, revealed at screening stage, was 80,3%.…”
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Low-Dose Aspirin as Primary Prophylaxis for Cardiovascular Events in Rheumatoid Arthritis: An Italian Multicentre Retrospective Study by Daniela Iacono, Serena Fasano, Ilenia Pantano, Virginia D’Abrosca, Piero Ruscitti, Domenico Paolo Emanuele Margiotta, Luca Navarini, Nicola Maruotti, Rosa Daniela Grembiale, Francesco Paolo Cantatore, Antonella Afeltra, Roberto Giacomelli, Gabriele Valentini

“…At multivariable analysis, arterial hypertension (HR 9.3) and hypercholesterolemia (HR 2.8) resulted to be positive predictors and ASA (HR 0.09) and hydroxychloroquine (HCQ) (HR 0.22) to be negative predictors. …”
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Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin by Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zenab B. Hamad Mohamed, Nuraniza Azahari, Asmah Hanim Bt. Hamdan, Che Anuar Che Mohamad

“…Lipid analysis approved the induction of hypercholesterolemia. A significant elevation (p<0.01) of serum AST and ALT levels showed by the HCD group was compared to C and C + H groups. …”
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Hubungan antara Proteinuria dan Hipoalbuminemia pada Anak dengan Sindrom Nefrotik yang Dirawat di RSUP Dr. M. Djamil Padang periode 2009-2012 by Pratiwi Dian Pramana, Mayetti Mayetti, Husnil Kadri

“…<br />Kata kunci: Anak dengan sindrom nefrotik, Proteinuria, Hipoalbuminemia<br />Abstract<br />Nephrotic syndrome consist of massive proteinuria, hypoalbuminemia, edema, and may be accompanied by hypercholesterolemia. Proteinuria is a major symptom of nephrotic syndrome, while the other clinical symptoms considered secondary manifestations. …”
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Effects of coenzyme q10 supplementation on metabolic and reproductive outcomes in obese rats by Gisela Belén Sarrible, María Victoria Bazzano, Caterina Koutsovitis, María Guillermina Bilbao, Rodrigo Hernán Da Cuña, Melanie Neira, Julián Alberto Bartolomé, Evelin Mariel Elia

“…CAF caused increased body weight gain (p < 0.01) associated with hyperglycemia, hypertriglyceridemia, and hypercholesterolemia (p < 0.05). Moreover, it caused a reduction in the number of AMH + follicles (p < 0.001), increasing follicular atresia (p < 0.05) and serum estradiol levels (p < 0.05). …”
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Prevalence of non-alcoholic fatty liver disease in out-patients of the Russian Federation: DIREG 2 study results by V. T. Ivashkin, O. M. Drapkina, I. V. Mayev, A. S. Trukhmanov, D. V. Blinov, L. K. Palgova, V. V. Tsukanov, T. I. Ushakova

“…The high prevalence of NANCFLD was revealed in primary or secondary patients admitted healthcare institutions for any reason including those with suspected NAFLD (patients with obesity, type 2 diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, hypercholesterolemia).…”
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Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6 by Byung Kil Park, Eun-Ah Lee, Hee-Youn Kim, Jun Choul Lee, Koon Soon Kim, Won Hoon Jeong, Ki Young Kim, Bon Jeong Ku, Sang Dal Rhee

“…The liver-specific knockout mice of the Mig-6 gene (Mig-6d/d) showed hepatomegaly and increased hypercholesterolemia. In this study, the biomarkers of insulin resistance and the effects of high-fat diets in the wild (Mig-6f/f) and Mig-6d/d mice were analyzed. …”
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Lipid Levels and Lung Cancer Risk: Findings from the Taiwan National Data Systems from 2012 to 2018 by Jung-Yueh Chen, Nai-Hui Chi, Ho-Shen Lee, Chia-Ni Hsiung, Chang-Wei Wu, Kang-Chi Fan, Meng-Rui Lee, Jann-Yuan Wang, Chao-Chi Ho, Jin-Yuan Shih

“…Hypertriglyceridemia was associated with a lower risk of adenocarcinoma (0.90 [0.84–0.96]) and a higher risk of small cell lung cancer (1.31 [1.11–1.55]). Hypercholesterolemia was associated with a lower risk of squamous cell carcinoma (0.84 [0.76–0.94]). …”
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Changes induced in mouse lipid metabolism by simultaneous impact of antisense oligonucleotide derivatives to <i>apoB</i>, <i>PCSK9</i>, and <i>apoCIII</i> mRNAs by S. I. Oshevski, Y. I. Ragino, E. V. Kashtanova, Y. V. Polonskaya, E. M. Stakhneva, V. P. Nikolin, N. A. Popova, N. A. Kolchanov, M. I. Voevoda

“…Development of new drugs able to decrease the level of “bad” cholesterol, in particular, based on antisense oligonucleotide derivatives (ASOs), remains relevant for the patients with familial hypercholesterolemia and/or intolerant to statins. The goal of the work was to assess the changes in the lipid metabolism caused by variants of joint impact of the ASOs targeted to the mRNAs of its key genes: apoB, PCSK9, and apoCIII. …”
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