Hydroxychloroquine’s Early Impact on Cone Density by Tomoko Ueda-Consolvo, Toshihiko Oiwake, Shinya Abe, Tomoko Nakamura, Ayaka Numata, Atsushi Hayashi

“…To evaluate early effects of hydroxychloroquine (HCQ) on the retina using adaptive optics (AO). …”
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Analysis of hydroxychloroquine prescriptions for COVID‐19 in Japan by Takashi Watari, Yasuharu Tokuda, Hiromizu Takahashi, Kiyosu Taniguchi, Kenji Shibuya

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Anti‐retinal Autoantibodies in Hydroxychloroquine Eye Toxicity by Samuel D. Good, Grazyna Adamus, Michael B. Gorin, Jordan Jacquez, Jennifer Grossman, Isao Matsuura, Ashira Hasan, Brian Skaggs, Maureen McMahon

“…Objective Autoimmune retinopathy and hydroxychloroquine (HCQ)‐related retinal toxicity share many similarities, raising the possibility autoimmunity plays a role in HCQ retinopathy. …”
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Liposomal Formulation of Hydroxychloroquine Can Inhibit Autophagy In Vivo by Wieslawa H. Dragowska, Jagbir Singh, Mohamed Wehbe, Malathi Anantha, Katarina Edwards, Sharon M. Gorski, Marcel B. Bally, Ada W. Y. Leung

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Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19 by Aliede E. in ‘t Veld, Manon A. A. Jansen, Luuk C. A. Ciere, Matthijs Moerland

“…The main basis for hydroxychloroquine (HCQ) treatment in COVID-19 is the compound’s ability to inhibit viral replication in vitro. …”
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A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment: A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment by Rajen Tailor, Ibrahim Elaraoud, Peter Good, Monique Hope-Ross, Robert A. H. Scott

“…The patient was on hydroxychloroquine 200 mg twice a day for eight years for the treatment of scarring alopecia. …”
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Early detection of the retinal bioelectrical dysfunction in patients treated by chloroquine/hydroxychloroquine by Wojciech Lubiński, Tomasz Kubacki, Marek Brzosko, Maciej Mularczyk

Subjects: “…chloroquine/hydroxychloroquine treatment…”
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Hydroxychloroquine-induced Sweet’s Syndrome: A Case Report and Literature Review by Gustavo Almeida-Silva, Joana Antunes, Inês Tribolet de Abreu, Filipe Monteiro, Pedro Vasconcelos, Luís Soares-Almeida, Paulo Filipe

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Risk versus Benefit of Using Hydroxychloroquine to Treat Patients with COVID-19 by George G. Zhanel, Michael A. Zhanel, Kevin F. Boreskie, Joseph P. Lynch, James A. Karlowsky

“…Hydroxychloroquine (HCQ), also known by its trade name Plaquenil®, has been used for over 50 years as a treatment for malaria, systemic lupus erythematosus, and rheumatoid arthritis. …”
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Optical coherence tomography characteristics in hydroxychloroquine retinopathy and the correlations with visual deterioration in Taiwanese by Shao-Kai He, Tso-Ting Lai, Yi-Ting Hsieh

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Physiologically-based pharmacokinetic modeling of enantioselective hydroxychloroquine kinetics and impact of genetic polymorphisms by Gabriella de Souza Gomes Ribeiro, Leandro Francisco Pippa, Fernanda de Lima Moreira, Natália Valadares de Moraes

Subjects: “…Hydroxychloroquine…”
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Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine by John P. O’Laughlin, Parag H. Mehta, Brian C. Wong

“…The patient had been treated with hydroxychloroquine for two years prior to presentation. …”
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LC-MS/MS Method for Determination of Hydroxychloroquine and Metabolites: Application in a Pharmacokinetic Study by Lili Cui, Zhipeng Wang, Shi Qiu, Mengwei Zhang, Yanping Liu, Fengjing Xu, Xinhua Song, Shouhong Gao, Wansheng Chen

“…Hydroxychloroquine (HCQ) was originally used as an antimalarial and immunomodulation drug. …”
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Efficacy and Safety of Antimalarial as Repurposing Drug for COVID-19 Following Retraction of Chloroquine and Hydroxychloroquine by Latarissa IR, Khairinisa MA, Iftinan GN, Meiliana A, Sormin IP, Barliana MI, Lestari K

“…During the pandemic, Chloroquine (CQ) and Hydroxychloroquine (HCQ) demonstrated good potential against COVID-19, but further studies showed both drugs had side effects that were more dangerous than the efficacy. …”
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Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome by Yumika Takaki, Atsushi Daimon, Misa Nunode, Tomohito Tanaka, Daisuke Fujita, Masahide Ohmichi

“…Recently, the addition of a novel antimalarial, hydroxychloroquine (HCQ), to the conventional treatment has shown the potential to prevent obstetric complications. …”
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COVID-19 Pneumonia in Patients on Chronic Hydroxychloroquine Therapy: Three Cases of COVID-19 Pneumonia by Awan K. Rahman, Adam G. Purdy, Peter T. Ender

“…Hydroxychloroquine has gained popularity as a potential preventative and treatment of COVID-19 pneumonia due to its in vitro activity against the virus. …”
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Innovative Lipid Nanoparticles Co-Delivering Hydroxychloroquine and siRNA for Enhanced Rheumatoid Arthritis Therapy by Yanru Feng, Xintong Pan, Ziqian Li, Yue Li, Ya’nan Sun, Shaokun Yang, Chaoxing He, Yunjie Dang, Lu Huang, Bai Xiang

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Decreased Autophagic Activity in Triple-Negative Breast Cancer Cells upon Hydroxychloroquine and Thymoquinone Combination Treatment by Tuğcan Korak, Merve Gulsen Bal Albayrak, Sevinc Yanar, Gürler Akpınar, Murat Kasap

“…Research indicates that hydroxychloroquine and thymoquinone modulate autophagy, potentially suppressing its activity. …”
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Hydroxychloroquine enhances insulin sensitivity and ameliorates abnormal lipid metabolism in obese women with polycystic ovary syndrome by Ruihan Wang, Shanqin Qi, Qi Wang, Jiajia Lang, Conghui Pang, Kehua Wang

Subjects: “…Hydroxychloroquine…”
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Decreased Perifoveal Sensitivity Detected by Microperimetry in Patients Using Hydroxychloroquine and without Visual Field and Fundoscopic Anomalies by A. Molina-Martín, D. P. Piñero, R. J. Pérez-Cambrodí

“…To evaluate the usefulness of microperimetry in the early detection of the ocular anomalies associated with the use of hydroxychloroquine. Methods. Prospective comparative case series study comprising 14 healthy eyes of 7 patients (group A) and 14 eyes of 7 patients under treatment with hydroxychloroquine for the treatment of rheumatologic diseases and without fundoscopic or perimetric anomalies (group B). …”
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