Q Fever Endocarditis in Northeast Iran by Ali Akbar Heydari, Ehsan Mostafavi, Masoumeh Heidari, Mina Latifian, Saber Esmaeili

“…According to the adjusted Duke criteria, Q fever endocarditis was confirmed, and the patient was successfully treated with doxycycline and hydroxychloroquine.…”
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Characteristics, pathogenic and therapeutic role of gut microbiota in immunoglobulin A nephropathy by Kaijin Yao, Lingqian Zheng, Wenmin Chen, Yina Xie, Chunling Liao, Tianbiao Zhou

“…Interestingly, therapies by modulating the gut microbiota, such as fecal microbiota transplantation, antibiotic treatment, probiotic treatment, Chinese herbal medicine Zhen Wu Tang treatment, gluten-free diet, and hydroxychloroquine treatment, can improve IgAN. In this review, the alteration of gut microbiota in IgAN, potential pathogenic roles of gut microbiota on IgAN and potential approaches to treat IgAN by modulating the gut microbiota are summarized.…”
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A Unique Case of Mycophenolate Induced Colitis after 10 Years of Use by Abhinav Goyal, Moiz Salahuddin, Yogesh Govil

“…A 31-year-old female with a history of lupus nephritis on Hydroxychloroquine, Prednisone, and Mycophenolate Mofetil (MMF) for 10 years presented to the hospital for ankle swelling. …”
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Assessment of the impact of COVID-19 on the hearing organ by Jan Piotrowski, Bianka Nowińska, Izabela Hądzlik

“…Additionally, drugs included in COVID-19 treatment regimens and administrated in intensive care units (ICU), such as chloroquine, hydroxychloroquine, azithromycin and furosemide, may be the cause of hearing impairment, due to their potential ototoxic effect. …”
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Pediatric Interstitial Lung Disease Masquerading as Difficult Asthma: Management Dilemmas for Rare Lung Disease in Children by EY Chan, Sharon D Dell

“…She did not have sustained improvement with systemic corticosteroids, hydroxychloroquine or clarithromycin. Cardiac catheterization confirmed the presence of secondary pulmonary hypertension. …”
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Hyper IgG4-Related Disease Presenting with Orbital Tumor and Immune Deficiency by Caroline G. Olson, Nancy Y. Olson

“…The patient was started on prednisone and tried several immunosuppressive medications including mycophenolate mofetil, methotrexate, hydroxychloroquine, and azathioprine with decrease in size of the orbital pseudotumor. …”
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Comparative-effectiveness research of COVID-19 treatment: a rapid scoping review by Sharon E Straus, Jesmin Antony, Andrea C Tricco, Rachel Warren, Erin Macdonald, Ba Pham, Milan Patel, Fatemeh Yazdi, Amruta Radhakrishnan, Marco Ghassemi, Patricia Rios, Chantal Williams, Naveeta Ramkissoon, Matthew P Muller, Nazia Darvesh, Gordon V Cormack, Maura R Grossman, Melissa Kampman, Reid Robson

“…The most common treatments were tocilizumab (11%), hydroxychloroquine (9%) and convalescent plasma (7%). The most common therapeutic categories were non-steroidal immunosuppressants (18%), steroids (15%) and antivirals (14%). …”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…FindingsIn this series of observational, retrospective, case-control, pharmacovigilance analyses of the FDA Adverse Event Reporting System, the odds of reporting the adverse event pemphigus were significantly elevated among individuals exposed to 11/36 previously reported trigger drugs namely, gold sodium thiomalate, penicillamine, piroxicam, rifampin, hydroxychloroquine, imiquimod, hydrochlorothiazide, irbesartan, lisinopril, nivolumab, and nifedipine.MeaningEnvironmental exposures such as drugs are relevant players in the pathogenesis of autoimmune diseases and clinicians who treat patients with autoimmune blistering diseases such as pemphigus should consider performing a detailed medication history leveraging this information regarding deleterious drug-disease interactions at initial evaluation as well as longitudinal monitoring of patients to better inform clinical care decisions.ImportancePemphigus vulgaris (PV) is a rare, potentially fatal autoimmune disease with pathogenic contributions from both genetic as well as environmental factors, notably drug exposures. …”
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Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature by Amna Ahmed, Alejandro Granillo, Ethan Burns, Kerri Glassner, Nishath Naseem, Christopher Force, Suzanne M. Crumley, Ashley Drews

“…We present a case of a young female on chronic prednisone and hydroxychloroquine for systemic lupus erythematosus (SLE) who was diagnosed with HSV-2 hepatitis after presenting with right-sided chest and abdominal discomfort. …”
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Porphyria Cutanea Tarda in a Patient with End-Stage Renal Disease: A Case of Successful Treatment with Deferoxamine and Ferric Carboxymaltose by Natacha Rodrigues, Fernando Caeiro, Alice Santana, Teresa Mendes, Leonor Lopes

“…Also, conventional treatment of PCT is compromised in these patients as hydroxychloroquine is contraindicated, phlebotomies with the stipulated frequency are poorly tolerated in already anaemia-prone patients, and iron-chelating agents are less efficient in removing iron and contribute to worsening anaemia. …”
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Systemic lupus erythematosus in a patient with 22q11.2 deletion syndrome: A case report and review of the literature by Chen Sun, Pingyang Han, Juzhen Yan

“…Treatment with prednisone, hydroxychloroquine and azathioprine resulted in improvement. …”
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Behçet’s disease in pregnancy: a case report and literature review by Xiangyue Li, Xuemei Huang, Xiaolan Yu

“…The final treatment regimen included azithromycin, hydroxychloroquine, prednisone, and low-molecular-weight heparin calcium. …”
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Anti-SARS-CoV-2 Biotherapeutics and Chemotherapeutics: An Insight into Product Specifications and Marketing Dynamics by Vijay Kotra, Dinakar Mallem, Anil Kumar Kanuri, Mahesh Reddy Burra, Shaik Nyamathullah, Looi Shu Ying, Khairul Anwar Husain, Ravi Varala, Madhadevi Sudhakar, Khang Wen Goh, Toong Hai Sam, Long Chiau Ming

“…There are several chemotherapeutics that have been studied for the treatment of COVID-19, including Paxlovid (Nirmatrelvir & Ritonavir) fixed dose combination, nirmatrelvir and ritonavir fixed dose combination, Remdesivir (Vekulary/Covifor) fixed dose combination, chloroquine and hydroxychloroquine, molnupiravir, favipiravir, Infliximab (Remsima®) fixed dose combination tocilizumab (Actimera), casirivimab+imdevimab (Ronapreve) fixed dose combination, ivermectin, methylprednisole. …”
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Coronavirus disease 2019 in kidney transplant recipients: a systematic review and meta-analysis by Quan Yao Ho, Rehena Sultana, Tung Lin Lee, Sobhana Thangaraju, Terence Kee, Htay Htay

“…It is uncertain whether high-dose corticosteroid or hydroxychloroquine reduces the risks of mortality in KTRs with COVID-19.…”
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Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient by Sirous Jafari, Zahra Jahani, Reihane Alikhani, SeyedAhmad SeyedAlinaghi, Malihe Hasannezhad, Faeze Salahshour, Ali Asadollahi-Amin

“…The combination of a chest tube, antibiotics (vancomycin 1 gr/bid and meropenem 1 g/bid), and antiviral (hydroxychloroquine 200 mg/bid and atazanavir 300 mg/daily) was prescribed, and continued treatment with antiviral and appropriate care for pneumomediastinum was successful. …”
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Central nervous system involvement in Whipple's disease: Report of a rare pathological entity and comparative review of treatment strategies and outcomes by Moustafa A. Mansour, MD, MSc, MPhil, Reem W. Malaeb, BS, Islam E. Elnemr, MD, Mohamed Abdel-Fattah El-Salamoni, MD, Hamdi Nabawi Mostafa, MD, Zarina Ahmadi, MD

“…The patient was successfully treated with a combination of intravenous ceftriaxone followed by oral doxycycline and hydroxychloroquine, resulting in significant symptom improvement and full recovery of neurological function. …”
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Common variable immunodeficiency: An uncommon cause of bronchiectasis, granulomatous disease, chronic liver disease, and enteropathy – Case report and review of literature by Veena Shamsudeen, Arun Hegde, Uday Bhanu Kovilapu, Nisha Verma, Anurag Jain

“…She was managed with immunoglobulin replacement therapy, along with hydroxychloroquine and steroids with good response.…”
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Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States by Zanthia Wiley, Sujan Reddy, Kara M. Jacobs Slifka, David C. Brandon, John Jernigan, Gilbert J. Kersh, Paige A. Armstrong

“…Treatment of chronic Q fever with vascular involvement includes a prolonged course of doxycycline and hydroxychloroquine (≥18 months) as well as early surgical intervention, which has been shown to improve survival. …”
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Management of a Novel Autoimmune Disease, COPA Syndrome, in Pregnancy by Archana Ayyar, Rachel D. Seaman, Kalpalatha Guntupalli, Mary C. Tolcher

“…On her first antepartum admission, rheumatology recommended management with hydroxychloroquine, inhaled corticosteroids (budesonide), and bronchodilators (albuterol inhaler) as needed. …”
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Clinical Outcomes in Patients with Cardiac Lupus: A Retrospective Study by K Maria Koshy, Tarun George, Sohini Das, J V Punitha, Sudha Jasmine Rajan, Bijesh Yadav, Thambu David Sudarsanam, Vijay Prakash Turaka

“…An elevated serum creatinine, elevated creatine Kinase–muscle/brain, neutrophilic leukocytosis, left ventricular systolic dysfunction, noninitiation of hydroxychloroquine, and the presence of neuropsychiatric lupus predicted mortality. …”
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