Using computer modeling to find new LRRK2 inhibitors for parkinson’s disease by María C. García, Sebastián A. Cuesta, José R. Mora, Jose L. Paz, Yovani Marrero-Ponce, Frank Alexis, Edgar A. Márquez

“…Free energy of binding calculation along with hydrogen bond occupancy analysis and RMSD of the ligand in the pocket show CRA_1801 as the best candidate to be repurposed as LRRK2 inhibitor.…”
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Recovery of the Intestinal Microbiota Metabolic Activity in Patients with Bronchial Asthma by O. Yu. Zolnikova, N. D. Potskhverashvili, N. I. Kokina

“…All patients underwent a generally accepted range of clinical laboratory tests, functional respiratory tests and a hydrogen breath test with lactulose to detect SIBO. …”
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Facile construction of polyoxometalate-modified polyaryletherketone-based hybrid membranes with enhanced proton conductivity by Bo Hu, Qiuchen Du, Yang Yang, Dengdeng Li, Jiawang Fu, Bailing Liu, Hong-Ying Zang, Yangguang Li, Haiming Xie, Zhongmin Su

“…Because of its structural characteristics, the nanosized PW12 induced precise hybridization of the nanophase structure of this ionomeric polymer and the formation of proton transport channels. Additionally, the hydrogen-bonding networks formed by PW12 and sulfonic acid groups increased the proton conductivity and mechanical strength of the resulting hybrid PEMs and improved the close-packed structure of the PEMs to achieve an appropriate balance between conductivity and fuel permeation. …”
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Determination of Benzalkonium Chloride in a Disinfectant by UV Spectrophotometry and Gas and High-Performance Liquid Chromatography: Validation, Comparison of Characteristics, and... by Mariia Smolinska, Roman Ostapiv, Mariia Yurkevych, Liubov Poliuzhyn, Olha Korobova, Ihor Kotsiumbas, Hryhorii Tesliar

“…The temperature of the detector was 250°C, and a mixture of hydrogen, helium, and air in a ratio of 30 : 8.5 : 350 was used in the split of the detector. …”
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Blue light irradiation combined with low-temperature storage further enhances postharvest quality of strawberries through improving antioxidant defense and cell wall metabolic acti... by Wei Lu, Wanqing Li, Keke Zhao, Xiaofeng Bai, Yuchang Zhang, Qingyun Li, Zhanjun Xue, Xin-Xin Wang

“…Additionally, increases of the enzymatic activities of antioxidant defense metabolism (e.g. superoxide dismutase (SOD) and peroxidase (POD)) accompanied with decreased levels of reactive oxygen species (ROS) (e.g. superoxide anion (O2−), and hydrogen peroxide (H2O2)) and the content of secondary metabolites (e.g. ascorbic acid (AsA)) accompanied with enhanced activities of ascorbate peroxidase (APX) and glutathione reductase (GR) were found in BL irradiated postharvest strawberries at the later stages of storage. …”
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Regulatory mechanism of exogenous myo-inositol improving high temperature stress tolerance of tomato seedlings by CHEN Yan, HAN Liyuan, DU Zilong, ZHU Dongxing, ZHU Weimin, ZHANG Yingying

“…Exogenous myo-inositol increased proline and soluble sugar contents and peroxidase activity, and decreased malondialdehyde, hydrogen peroxide, and superoxide anion contents in tomato seedlings at high temperature. …”
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Exothermic characteristics evaluation of the Pt coated α-Al2O3 catalyst in bed for passive airborne radioactive material reduction system under forced flow conditions by Hyun Chul Lee, Jungjin Bang, Kiwan Jang, Min Beom Heo, Doo Yong Lee, Daewoo Kim, Chang-Ha Lee

“…Exothermic characteristics evaluation tests were conducted by varying the hydrogen volume fraction and face velocity, measuring heat generation in the catalytic bed under each condition. …”
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ALMA Observations of Solar Spicules in a Polar Coronal Hole by T. S. Bastian, C. Alissandrakis, A. Nindos, M. Shimojo, S. M. White

“…The spicules observed at mm- λ are seen in absorption against coronal EUV emission, allowing us to estimate the column depth of neutral hydrogen. Spicular emission at mm- λ , due to thermal free–free radiation, allows us to estimate the electron number density as a function of height. …”
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Azospirillum brasilense and organomineral fertilizer co-inoculated with Bradyrhizobium japonicumon oxidative stress in soybean by Fernanda Barros, Reginaldo de Camargo, Regina Maria Lana, Miguel Henrique Franco, Mayara Cristiana Stanger, Vanderley José Pereira, Ernane Lemes

“…Plant protection to stresses happened mainly by reductions in the superoxide dismutase activity, lipid peroxidation, and hydrogen peroxide concentration. The co-inoculation of A. brasilense with B. japonicum enhanced the proline activity at the V3 and R5 soybean phenological stage compared to A. brasilense inoculated alone.Conclusion The studied organomineral fertilizer is an efficient inoculant carrier for A. brasilense in soybean plants via seed treatment. …”
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Rational design of novel phenol ether derivatives as non-covalent proteasome inhibitors through 3D-QSAR, molecular docking and ADMET prediction by Miao Yuan, Hanwen Ji, Fengxin Sun, Qiang Chen, Ping Cheng

“…The results suggested that hydrogen bond and hydrophobic interaction played a key role in binding interaction between the receptor and ligand. …”
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Molecular biological research and molecular homologous modeling of Bw.03 subgroup by WANG Li, KONG Yongkui, JIN Huifang, LIU Xin, XIE Ying, LIU Xue, CHANG Yanli, WANG Yafang, YANG Shumiao, ZHU Di, YANG Qiankun

“…Compared with the wild type, the structure of Bw.03GT was partially changed, and the intermolecular force analysis showed that the original three hydrogen bonds at 241 position disappeared. [Conclusion] Blood group molecular biology examination is helpful for the accurate identification of ambiguous blood group. …”
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Structural Characterization of B-DNA d(CGTGAATTCACG)₂ in Complex with the Specific Minor Groove Binding Fluorescent Marker Hoechst 33342 by Hristina Sbirkova-Dimitrova, Rusi Rusew, Hristo Gerginov, Annie Heroux, Boris L. Shivachev

“…It interacted with DNA through hydrogen bonding and van der Waals forces. The structural comparison revealed that Hoechst 33342 inserts itself in the minor groove in a strongly specific manner, displacing the ordered spine waters.…”
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The Effect of Different Sulphur Sources Applied at Various Rates on Soil pH by Fatma Nur Kılıç, Osman Sönmez

“…Soil pH, governed by the relative concentrations of hydrogen () and hydroxyl () ions, is a key factor affecting the chemical, physical, and biological properties of soils. …”
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Surface functionalized mesoporous polydopamine nanocomposites for killing tumor cells through collaborative chemo/photothermal/chemodynamic treatment by Yi Ouyang, Yan Chen, Ting Xu, Yihao Sun, Sheng Zhao, Chunmei Chen, Yixin Tan, Liang He, Hui Liu

“…Results: When uptaken by tumor cells, the nanocomposites can degrade to produce O2, release CPT, and generate manganese (Mn2+) under the stimulation of hydrogen peroxide (H2O2) and acid. The released CPT and Mn2+ can act as chemotherapeutic drug and Fenton-like agent, respectively. …”
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The Effects of Active Galactic Nuclei Feedback on the Lyα Forest Flux Power Spectrum by Megan Taylor Tillman, Blakesley Burkhart, Stephanie Tonnesen, Simeon Bird, Greg L. Bryan

“…The effects of AGN feedback can be seen across a large range of wavenumbers (1.5 × 10 ^−3  <  k  < 10 ^−1 s km ^−1 ) changing the ionization state of hydrogen in the IGM through heating. AGN feedback can also alter the thermal evolution of the IGM and thermally broaden individual Ly α absorbers. …”
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Cost minimization analysis of nasopharyngoscope reprocessing in community practice by Ameen Biadsee, Lauren Crosby, Winsion Chow, Leigh J Sowerby

“…., Markham, Canada), (2) soak with accelerated hydrogen peroxide solution (Revital-Ox; Steris Canada Inc., Mississauga, Canada), (3) disinfection with chlorine dioxide wipe (Tristel Trio Wipes System; Tristel plc., Cambridgeshire, UK), (4) UV-C light system (UV Smart, Delft, The Netherlands). …”
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Polymer-metal powders melt extrusion printing to produce high-density, high-conductivity pure copper components by Xiuhu Guo, Junnan Liu, Lu Li, Xiaoying Cui, Muhammad Dilawer Hayat, Peng Cao, Zhentao Yuan, Xiao Wang, Xiulin Chen

“…The debounded parts were then sintered at 1050 °C in argon-hydrogen (H∼10 vol %) mixed gas. The results show that the copper parts produced with a 0.6 mm nozzle and 0.1 mm layer height exhibited the best performance, achieving a density greater than 98 %, conductivity of ∼93 % IACS, ultimate tensile strength of 198 MPa, and elongation at break of 34 %. …”
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Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evalu... by Shanshan Zhu, Zhichang Qiu, Xuguang Qiao, Geoffrey I.N. Waterhouse, Wenqing Zhu, Wenting Zhao, Qiuxia He, Zhenjia Zheng

“…Encapsulating OA+UA with ALPs (ALP:OA+UA, 50:1; OA:UA, 1:1) changed the crystalline nature to a more amorphous state through hydrogen bonding and involving O–H/C–O/O–C–O groups. …”
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H₂S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins by Rahib K. Islam, Erinn Donnelly, Erminia Donnarumma, Fokhrul Hossain, Jason D. Gardner, Kazi N. Islam

“…Endogenously produced hydrogen sulfide (H₂S) is critical for cardiovascular homeostasis. …”
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A novel de novo GABRA2 gene missense variant causing developmental epileptic encephalopathy in a Chinese patient by Li Yang, Xingyu Wan, Ran Hua, Junhong Jiang, Baotian Wang, Rui Tao, De Wu

“…Structural modeling suggested that this variant is located within the extracellular domain, which may disrupt hydrogen bonding interactions with GABRB3 and GABRG2. …”
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