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461
Efficacy of Rg1-Oil Adjuvant on Inducing Immune Responses against Bordetella bronchiseptica in Rabbits
Published 2021-01-01“…Rg1 (100 μg) plus oil significantly improved the immune effect of B. bronchiseptica vaccine at both the humoral and cellular levels. Rg1-oil adjuvant increased the levels of IL-2 and IL-4 in rabbits after immunization. …”
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462
Inborn errors of immunity (primary immunodeficiencies)
Published 2025-01-01“…IEIs can be broadly classified as disorders of adaptive immunity (e.g., combined or humoral immunodeficiencies) or of innate immunity (e.g., phagocyte and complement disorders). …”
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463
An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape
Published 2025-01-01“…BackgroundAlthough immunoglobulin (Ig) alleles play a pivotal role in the antibody response to pathogens, research to understand their role in the humoral immune response is still limited.MethodsWe retrieved the germline sequences for the IGHV from the IMGT database to illustrate the amino acid polymorphism present within germline sequences of IGHV genes. …”
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464
Caso clínico radiológico de colangitis piógena recurrente
Published 2021-10-01“…Se presenta paciente de 28 años, bangladeshi, ingresado en el Cuban Hospital de Qatar por dolor abdominal, fiebre moderada e ictericia ligera, elevación de las enzimas hepáticas y pancreáticas, además de presentar patrón humoral de colestasis. La ecografía abdominal y la tomografía de abdomen con contraste endovenoso detectaron vesícula biliar distendida con pared gruesa, litiasis en las vías biliares extra e intrahepáticas con dilatación de las mismas y escasa cantidad de líquido y edema peri pancreático, concluyéndose como pancreatitis aguda secundaria a colecistitis litiásica. …”
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465
Immune Dysfunction in Tourette Syndrome
Published 2013-01-01“…The association between immunity and neurodevelopmental disorders has been extensively investigated in autism, suggesting a potential involvement of both cellular and humoral immunity in the establishment of synaptic connectivity modulation during development. …”
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466
The Influence of Nanoparticle on Vaccine Responses against Bacterial Infection
Published 2022-01-01“…Nanovaccines are more efficient than traditional vaccines since they could potentially induce both humoral and cellular immune reactions. Various studies have shown that nanoparticles with multiple compounds have been designed as delivery systems or as adjuvants for vaccines. …”
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467
White Magic, Black Humour: Ella D’Arcy’s Narrative Strategies
Published 2022-10-01“…Of the New Woman writers who wrote humour, Ella D’Arcy is one of the more elusive. Her humorous writing takes the form of satire which depends on a double reading. …”
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468
Allegorical and Pamphlet Rhetoric in Petko R. Slaveykov’s Verse Fables and Journalistic Works
Published 2024-01-01“…A significant portion of the article is dedicated to analyzing the allegorical imagery in the humorous-satirical aspects of Slaveykov’s early journalistic work, especially in the newspaper ‘Gayda’ (1863). …”
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469
Pekić's paradoxology and Serbian identity
Published 2024-01-01“…This Serbian writer permeates and nuances shorter genres in the light of paradoxes and NEO-aphoristic microstructural units with a distinct polemic approach and a humorous charge that help a more complete understanding of the hero's Serbian identity. …”
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470
A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective against HSV-2 intravaginal challenge in mice.
Published 2024-01-01“…Replication-incompetent adenoviral vectors are potent inducers of humoral and cellular immune responses in humans. We have designed an adenoviral vector type 35 (Ad35)-based vaccine encoding the HSV-2 major surface antigen gD2 (Ad35.HSV.gD2). …”
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471
Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response
Published 2022-01-01“…Th2 immune response is essential for providing protection against pathogens and orchestrating humoral immunity. However, excessive Th2 immune response leads to the pathogenesis of Th2 inflammation diseases, including asthma, allergic rhinitis, and atopic dermatitis. …”
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472
Experimental Immunization Based on Plasmodium Antigens Isolated by Antibody Affinity
Published 2015-01-01“…The presence of specific antibodies in vaccinated mice serum was studied by immunoblot analysis at different days after vaccination and showed an intensive immune response to a wide range of antigens with molecular weight ranging between 22 and 250 kDa. The humoral response allowed delay of the infection after the inoculation to high lethal doses of P. yoelii yoelii 17XL resulting in a partial protection against malaria disease, although final survival was managed in a low proportion of challenged mice. …”
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473
AMINOSELETON-BASED CORRECTION OF IMMUNE STATUS IN WHITE RATS VACCINATED FROM SALMONELLOSIS AND CHRONICALLY EXPOSED TO T-2 TOXIN
Published 2018-04-01“…Decrease in specific humoral immunity and natural resistance caused by chronic T-2 toxicosis following experimental infection with Salmonella cholerae suis had a negative effect on the animal lifetime and safety.…”
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474
Regulatory T Cells in the Immunodiagnosis and Outcome of Kidney Allograft Rejection
Published 2013-01-01“…AR may be broadly classified into humoral as well as cellular rejection. Cellular rejection develops when donor alloantigens, presented by antigen-presenting cells (APCs) through class I or class II HLA molecules, activate the immune response against the allograft, resulting in activation of naive T cells that differentiate into subsets including cytotoxic CD8+ and helper CD4+ T cells type 1 (TH1) and TH2 cells or into cytoprotective immunoregulatory T cells (Tregs). …”
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475
Teoría celular de la coagulación: de las cascadas a las membranas celulares
Published 2011-04-01“…El modelo clásico de la coagulación, propuesto hace más de 40 años, separa las fases celular y humoral de la coagulación. Considera que el proceso de hemostasia se consigue a través de la activación secuencial de enzimas efectoras en dos vías independientes: la extrínseca y la intrínseca. …”
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476
Follicular Helper CD4+ T Cells in Human Neuroautoimmune Diseases and Their Animal Models
Published 2015-01-01“…Follicular helper CD4+ T (TFH) cells play a fundamental role in humoral immunity deriving from their ability to provide help for germinal center (GC) formation, B cell differentiation into plasma cells and memory cells, and antibody production in secondary lymphoid tissues. …”
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477
Cloning and Characterization of Immunological Properties of Haemophilus influenzae Enolase
Published 2021-01-01“…Both in silico and experimental results showed that recombinant enolase from H. influenzae is immunogenic that could induce a humoral immune response; this was observed mediating the generation of specific polyclonal antibodies anti-rNTHiENO that recognize typeable and nontypeable H. influenzae strains. …”
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478
Simulating Immune Interference on the Effect of a Bivalent Glycoconjugate Vaccine against Haemophilus influenzae Serotypes “a” and “b”
Published 2016-01-01“…We developed a stochastic simulation model of humoral immune response to investigate the antigenic challenge of a bivalent combined glycoconjugate vaccine and a bivalent unimolecular glycoconjugate vaccine. …”
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479
Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4-CD8-γδ+ T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination
Published 2013-01-01“…The measurement of vaccine-induced humoral and CD4+ and CD8+ cellular immune responses represents an important correlate of vaccine efficacy. …”
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480
Virus-Mimicking Polymer Nanocomplexes Co-Assembling HCV E1E2 and Core Proteins with TLR 7/8 Agonist—Synthesis, Characterization, and In Vivo Activity
Published 2025-01-01“…Supramolecular co-assembly and co-presentation of the HCV envelope E1E2 heterodimer complex and core protein presents an attractive vaccine design strategy for achieving effective humoral and cellular immunity. With this objective, the two antigens were non-covalently assembled with an immunostimulant (TLR 7/8 agonist) into virus-mimicking polymer nanocomplexes (VMPNs) using a biodegradable synthetic polyphosphazene delivery vehicle. …”
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