Suggested Topics within your search.
Suggested Topics within your search.
-
441
New Possibilities for the Treatment of Crohn’s Disease
Published 2019-12-01“…The drug interrupts the cascade of humoral and cellular reactions leading to transmural inflammation of the intestinal wall by blocking the interaction of the p40 subunit with the IL-12Rβ1 chain on the surface of T-lymphocytes and NK cells. …”
Get full text
Article -
442
Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting
Published 2025-01-01“…Such tools facilitated the search for potential therapeutic agents and accelerated epidemiological studies on post-infection and post-vaccination humoral immunity. This review focuses on the use of pseudoviruses as a model for large-scale applications to study enveloped viruses.…”
Get full text
Article -
443
Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants
Published 2019-01-01“…Aluminum-based adjuvants are the most commonly used, the safest, and have the best efficacy, due to the triggering of a strong humoral response, albeit generating a weak induction of cell-mediated immune response. …”
Get full text
Article -
444
The Immune Response and Its Therapeutic Modulation in Bronchiectasis
Published 2012-01-01“…Inflammatory cells are present in both the airways as well as the lung parenchyma, and multiple mediators of immune cells including proteases and cytokines or their humoral products are increased locally or in the periphery. …”
Get full text
Article -
445
'Just because' Constructions in Spoken and Written New Zealand English
Published 2020-12-01“…Just because (JB) is widely used and has been a target of commentary and humorous use by English speakers and aroused some interest among linguists, who have investigated its syntax, semantics, and derivation. …”
Get full text
Article -
446
‘I should like to see a woman smoking while she was nursing her baby’: The New Woman, Crossdressing, and Humour in Horace William Bleackley’s Une Culotte (1894)
Published 2022-10-01“…Then I examine how as a male New Woman writer Bleackley successfully uses female cross-dressing to humorous effect in order to empower the New Woman with opportunities that extend beyond the parameters of home. …”
Get full text
Article -
447
Production and development of vaccines for ornithobacterium rhinotracheale infection in turkeys
“…The vaccine containing mineral oil and ginseng as adjuvant induced significantly greater humoral immune response than others. Also, vaccine containing mineral oil and ginseng as adjuvant was determined to be more effective in the field trials in a company privately producing turkeys.…”
Get full text
Article -
448
No-Way Out: Being Entrapped in Wedlock Plays of Alan Ayckbourn: How the Other Half Loves and The Garden
Published 2023-08-01“…Although marital dissatisfaction, infidelity, lack of communication between couples are serious problems in modern world, Ayckbourn’s presenting this problem humorously makes him outstanding among his contemporaries. …”
Get full text
Article -
449
„Sprache macht den Freigang der Gedanken möglich“. Zu den sprichwörtlichen Aphorismen von Franz Hodjak
Published 2025-02-01“…Such anti-proverbs express his humorous, ironic or cynical view of modern life. That is also the case with numerous proverbial expressions whose metaphors add an impressive expressiveness to his thoughts. …”
Get full text
Article -
450
The Myth of Don Juan Onstage up to and through Victorian Times
Published 2017-11-01“…The passage from the seventeenth century’s moralising vision of Don Juan to its humorous counterpart in Victorian times constitutes the object of study of this article, which traces the inseparable trajectories of Don Juanesque works in the two countries. …”
Get full text
Article -
451
The Value of Compulsory Military Service in the Soviet Army (1967–1990) from the Conscripts’ Perspective
Published 2024-12-01“…Although the length of service typically ranged from 2 to 3 years, for some men, it remains a significant life adventure or a troubling memory, often revisited through humorous stories or a desire to connect with others who share similar experiences. …”
Get full text
Article -
452
Bathing Practices as a Religious and Medical Encounter: Water, Climate and Health Across Monsoon Asia
Published 2024-12-01“…The research highlights how bathing was considered essential for maintaining bodily balance—a concept analogous to humoral theory in Galenic medicine—across different climatic and environmental conditions, particularly during the monsoon season. …”
Get full text
Article -
453
An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2
Published 2020-01-01“…This vaccine peptide could simultaneously elicit humoral and cell-mediated immune responses. We hope to confirm our findings by adding complementary steps of both in vitro and in vivo studies to support this new universal predicted candidate.…”
Get full text
Article -
454
Gastro-intestinal involvement in systemic sclerosis
Published 2017-01-01“…Vasculopathy, cellular and humoral immunity, and diffuse fibrosis are the principal pathogenetic mechanisms in SSc and begin with autoantibody-mediated neuronal damage followed by muscular damage and fibrosis. …”
Get full text
Article -
455
A Rare Extraskeletal Osteosarcoma Appearing After 55 Years on a Large Stage 3 Burn Scar
Published 2018-01-01“…Deep tissues are probably less subject to severe insult than is the epithelial layer during physical insult, suggesting that soft tissues transform to a lesser extent during the late stages of tumoral development as in an immunocompromised district with altered local immune defense with both cellular and humoral defense affected. Most authors claim that tumors are almost squamous cell carcinomas, although other types of malignancies such as basal cell carcinoma and, to a lesser extent, melanoma can also be seen. …”
Get full text
Article -
456
The intestinal microbiome as a separate organ
Published 2014-12-01“…Interaction of bacteria with the «host» reminds cooperation of usual cells and can be carried out due to receptor binding, paracrine and humoral pathways, as well as due to phagocytosis and endocytosis. …”
Get full text
Article -
457
A Critique of the Literary School of Critical Realism in Iran (Based on the Stories of “Farsi Shekar Ast/Persian is Sugar” and “Gileh Mard”)
Published 2021-12-01“…Folk, fluent, simple, and humorous language replaced the court and official language. …”
Get full text
Article -
458
Contribution of long-lived plasma cells to antibody-mediated allograft rejection
Published 2024-12-01“…A subset of these plasma cells can survive for extended periods in a suitable survival niche and mature into long-lived plasma cells (LLPCs), which are a cellular component of humoral memory. The current understanding of LLPCs is limited due to their scarcity, heterogeneity, and absence of unique markers. …”
Get full text
Article -
459
The unique activity of the bone morphogenetic protein TGH4 affects the embryonic development of Trichinella spiralis and the establishment of vaccine protection
Published 2025-02-01“…The construction of a protein mutant without activation potential confirmed that BMP activity had a negative regulatory effect on the establishment of immune protection by affecting the innate, adaptive, and humoral immunity of mice. Stripping protein activity can enhance immune protection and host resistance to T. spiralis. …”
Get full text
Article -
460
Rational engineering of minimally immunogenic nucleases for gene therapy
Published 2025-01-01“…However, cellular and humoral immunogenicity of genome editing tools, which originate from bacteria, complicates their clinical use. …”
Get full text
Article