High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome by Tao Hong, Jiao-Yang Li, Ya-Di Wang, Xiao-Yan Qi, Zhe-Zhen Liao, Poonam Bhadel, Li Ran, Jing Yang, Bin Yan, Jiang-Hua Liu, Xin-Hua Xiao

“…This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in humans. Methods. A total of 131 consecutive patients with MetS, and 162 age-matched, healthy subjects were recruited for this study. …”
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Identification and characterization of Serratia nematophila and Acinetobacter guillouiae from putrid-skin disease lesions in farmed Chinese spiny frog (Quasipaa spinosa) by Ling Guo, Xiyu Jin, Dan Yang, Li Wei, Jie Chen, Zhihua Lin, Li Ma

“…ABSTRACT Serratia and Acinetobacter are recognized as significant opportunistic pathogens affecting aquatic animals and humans. However, their infections in amphibians are poorly documented, and their pathogenicity to the Chinese spiny frog (Quasipaa spinosa) remains unexplored. …”
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Microplastics in beach sediments, seawater, and common fish in tourist destinations by M. Go, A. Ybanez, A. Ilano, F. Cababat, L. De La Calzada

“…BACKGROUND AND OBJECTIVES: The global concern over microplastic pollution has been on the rise, primarily due to its detrimental effects on marine ecosystems and the potential health risks it poses to humans. Tourism activities are the main sources of plastic waste that deteriorates into microplastics. …”
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The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells by Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin

“…Copper (Cu) is a global environmental pollutant that poses a serious threat to humans and ecosystems. Copper induces developmental neurotoxicity, but the underlying molecular mechanisms are unknown. …”
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Therapeutic potential of Chromolaena odorata, Vernonia amygdalina, and Cymbopogon citratus against pathogenic Bacteria by Udensi Justina Ugochi, Anyanwu Charles Obinna, Emedoh Andrew Emeka, Anyanwu Emilia Oluchi, Danladi Makeri, Pius Theophilus, Ezera Agwu

“…Since the promising findings were based on an in vitro study, we recommend clinical trials to establish safe and effective doses of those plant extracts in humans.…”
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NKp46 enhances type 1 innate lymphoid cell proliferation and function and anti-acute myeloid leukemia activity by Rui Ma, Zhenlong Li, Hejun Tang, Xiaojin Wu, Lei Tian, Zahir Shah, Ningyuan Liu, Tasha Barr, Jianying Zhang, Sean Wang, Srividya Swaminathan, Guido Marcucci, Yong Peng, Michael A. Caligiuri, Jianhua Yu

“…This can be reversed by injecting NKp46+ ILC1s into NKp46 knock-out mice. Human NKp46+ ILC1s exhibit stronger cytokine production and cytotoxicity than their NKp46− counterparts, suggesting that NKp46 plays a similar role in humans. …”
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Search for and functional annotation of multi-domain PLA2 family proteins in flatworms by M. E. Bocharnikova, I. I. Turnaev, D. A. Afonnikov

“…PLA2 enzymes were characterized in detail in model organisms and humans. However, their presence and functional role in non-model organisms is poorly understood. …”
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Development of single-pin, un-barbed, pole-tagging of free-swimming dolphins and sharks with satellite-linked transmitters by Michael J. Moore, Thomas M. Lanagan, Randall S. Wells, Jason Kapit, Aaron A. Barleycorn, Jason B. Allen, Robin W. Baird, Camrin D. Braun, Gregory B. Skomal, Simon R. Thorrold

“…Delphinid skin has unique polymodal axon bundles that project into the epidermis, perhaps a factor in their uniquely fast response, which is 10 × faster than humans. Their primary reaction to tagging is to abduct the flippers and roll the fin out of the TADpole holster. …”
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Contagious acquisition of antimicrobial resistance is critical for explaining emergence in western Canadian feedlots—insights from an agent-based modelling tool by Dana Ramsay, Wade McDonald, Michelle Thompson, Nathan Erickson, Sheryl Gow, Nathaniel D. Osgood, Cheryl Waldner

“…IntroductionAntimicrobial resistance (AMR) is a growing threat to the efficacy of antimicrobials in humans and animals, including those used to control bovine respiratory disease (BRD) in high-risk calves entering western Canadian feedlots. …”
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Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil by Débora de Meneses, Ana G. Stoffella-Dutra, Vicenzo S. Blaso, Iara M. de Almeida, Karolina L. Dias, Iago José da S. Domingos, Gabriela P. Ribeiro, Wendel Coura-Vital, Alexandre B. Reis, Thallyta M. Vieira, Giliane de S. Trindade

“…Domestic animals can share viral pathogens with humans, acting mainly as a bridge host. The <i>Orthopoxvirus</i> genus hosts important zoonotic species that have emerged in urban areas worldwide. …”
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An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity by Pierre Guermonprez, Le Tu Anh, Louis Renaud, Pierre Nioche, Eric Krejci, Aurélie Alleaume-Butaux, Nicolas Battaglini, Vu Thi Thu, Sébastien Sanaur, Benoît Piro

“…Detection of Ribonucleic acids (RNA) is a critical step in the identification of viral or bacterial infections in humans and animals. Reverse transcriptase-polymerase chain reaction (RT-PCR) remains the gold standard, but clustered regularly interspaced short palindromic repeats linked to a Cas endoribonuclease particle (CRISPR/Cas) have recently revolutionized the recognition step of two RNAs, i.e. the CRISPR-RNA (crRNA) and the target, providing a much better selectivity compared to the naked hybridization on which RT-PCR is based. …”
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Whole-genome sequencing surveillance of Siberian tick-borne encephalitis virus (TBEV) identifies an additional lineage in Kyrgyzstan by Jake D'Addiego, Mollie Curran-French, Jack Smith, Asankadyr T Junushov, Irena Breininger, Barry Atkinson, John Hay, Roger Hewson

“…Differences in virulence between TBEV subtypes have been described, with the Far Eastern subtype causing the most severe disease in humans. Considering the emergence of new TBEV foci, the genetic characterisation of the virus in endemic regions is crucial to not only better understand its epidemiology, but also to identify possible genetic determinants of virulence, as well as develop accurate diagnostics and therapeutics.In our previous study, we identified TBEV in six localities of the Kyrgyz Republic (Kyrgyzstan), and Ala-Archa National Nature Park as a focus of TBEV transmission. …”
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Blinding assessment in randomised sham-controlled trials of acupuncture:protocol for a systematic survey by Ling Li, Xin Sun, Jiali Liu, Minghong Yao, Yong Fu, Jiahui Yang, Xiaochao Luo

“…The objectives of this study are the following: (1) to investigate the proportion and study characteristics of sham-controlled trials reporting on blinding assessment, (2) to assess the blinding effectiveness of different types of sham acupuncture, (3) to investigate the relationship between blinding effectiveness and effect sizes in acupuncture RCTs.Methods and analysis We will search PubMed and EMBASE from inception to 1 January 2025 to identify RCTs that compared acupuncture with sham acupuncture in humans with any disease or symptom, with no restrictions on language. …”
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The regulatory role of cystatin C in autophagy and neurodegeneration by T. A. Korolenko, A. B. Shintyapina, A. B. Pupyshev, A. A. Akopyan, G. S. Russkikh, M. A. Dikovskaya, V. A. Vavilin, E. L Zavjalov, M. A. Tikhonova, T. G. Amstislavskaya

“…The aim: to study the role of cystatin C in neurodegeneration and evaluate the results in relation to the mechanism of autophagy. In our study on humans, a higher concentration of cystatin C was noted in cerebrospinal fluid than in serum; much lower concentrations were observed in other biological fluids (intraocular fluid, bile, and sweat). …”
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Animal Brucellosis in Egypt: Review on Evolution, Epidemiological Situation, Prevalent <i>Brucella</i> Strains, Genetic Diversity, and Assessment of Implemented National Control Me... by Ahmed M. S. Menshawy, Acacia Ferreira Vicente, Yamen M. Hegazy, Vitomir Djokic, Mahmoud E. R. Hamdy, Luca Freddi, Essam M. Elbauomy, Ashraf E. Sayour, Claire Ponsart, Nour H. Abdel-Hamid

“…Increasing awareness through educational campaigns is compulsory to reduce brucellosis transmission risk to livestock/humans.…”
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Peningkatan Performa Ensemble Learning pada Segmentasi Semantik Gambar dengan Teknik Oversampling untuk Class Imbalance by Arie Nugroho, M. Arief Soeleman, Ricardus Anggi Pramunendar, Affandy Affandy, Aris Nurhindarto

“…Abstract The development of technology and the increasingly high lifestyle of humans produce abundant data. These data can be in the form of structured and unstructured data. …”
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The current state of knowledge on the role of NKG2D ligands in multiple sclerosis and other autoimmune diseases by Aleksandra Pogoda-Wesołowska, Nina Sługocka, Agnieszka Synowiec, Klaudia Brodaczewska, Marcin Mejer-Zahorowski, Maciej Ziękiewicz, Wojciech Szypowski, Piotr Szymański, Adam Stępień

“…The activating receptor belonging to the NKG2D is stimulated by specific ligands: in humans these are major histocompatibility complex (MHC) class I polypeptide–related sequence A (MICA) and MHC class I polypeptide-related sequence B (MICB) proteins and UL16 binding 1–6 proteins (ULBP1-6). …”
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The medial and lateral orbitofrontal cortex jointly represent the cognitive map of task space by Liwei Tan, Yidan Qiu, Lixin Qiu, Shuting Lin, Jinhui Li, Jiajun Liao, Yuting Zhang, Wei Zou, Ruiwang Huang

“…However, it remains unclear how the medial OFC (mOFC) and lateral OFC (lOFC) contribute to the formation of cognitive maps in humans. By performing a multi-step sequential task and multivariate analyses of functional magnetic resonance imaging (fMRI) data, we found that the mOFC and lOFC play complementary but dissociable roles in this process. …”
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Polystyrene nanoparticles induce DNA damage and apoptosis in HeLa cells by Antonia Feola, Manoj Madheswaran, Grazia Romano, Awet Ghebretinsae Tewelde, Eunice Wairimu Maina, Gianluca D'Abrosca, Maria della Valle, Mariacristina Cocca, Maria Emanuela Errico, Carla Isernia, Roberto Fattorusso, MariaTeresa Gentile, Gaetano Malgieri

“…Due to their small size and chemical composition, they can interact with biological systems in ways that larger plastic particles cannot. Humans are continuously exposed to NPs and several studies showed the potentially toxic effects of these latter on health. …”
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Legionella pneumophila IrsA, a novel, iron-regulated exoprotein that facilitates growth in low-iron conditions and modulates biofilm formation by Alberto E. Lopez, Joshua Mayoral, Huaixin Zheng, Nicholas P. Cianciotto

“…L. pneumophila exists in many natural and human-made water systems and can be transmitted to humans through inhalation of contaminated water droplets. …”
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