Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity by Els F. Halff, Sridhar Natesan, David R. Bonsall, Mattia Veronese, Anna Garcia-Hidalgo, Michelle Kokkinou, Sac-Pham Tang, Laura J. Riggall, Roger N. Gunn, Elaine E. Irvine, Dominic J. Withers, Lisa A. Wells, Oliver D. Howes

“…Positron emission tomography (PET) using the radiotracer [18F]-FDOPA provides a tool for studying brain dopamine synthesis capacity in animals and humans. We have previously standardised a micro-PET methodology in mice by intravenously administering [18F]-FDOPA via jugular vein cannulation and assessment of striatal dopamine synthesis capacity, indexed as the influx rate constant KiMod of [18F]-FDOPA, using an extended graphical Patlak analysis with the cerebellum as a reference region. …”
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In vitro study reveals antimicrobial activity of essential oils against Klebsiella pneumoniae isolates from Nile tilapia by D. Vaneci-Silva, R. Nakamura-Silva, M. Oliveira-Silva, A. Pitondo-Silva, I. M. Assane, F. Pilarski

“…This bacterium is commonly associated with urinary tract infections, pneumonia, and septicemia in humans. Controlling bacterial infectious diseases in fish is a significant challenge in aquaculture. …”
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Lactylation-driven TNFR2 expression in regulatory T cells promotes the progression of malignant pleural effusion by Yao Liu, Qiong Zhou, Siyu Zhang, Wenbei Peng, Haolei Wang, Xuan Xiang, Linlin Ye, Xiaoshan Wei, Zihao Wang, Qianqian Xue

“…Malignant pleural effusion (MPE) from humans and mouse was used to investigate the potential mechanisms by which lactate regulates TNFR2 expression.Results Treg cells with high TNFR2 expression exhibited elevated levels of immune checkpoint molecules. …”
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An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

“…African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense, and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and T. b rhodesiense are responsible for chronic and acute human African trypanosomiasis (HAT), respectively. …”
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Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

“…This result may confirm the hypothesis about the selection of this allele in the course of human migration into areas with unfavorable climatic conditions.…”
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Acute administration of NLX-101, a Serotonin 1A receptor agonist, improves auditory temporal processing during development in a mouse model of Fragile X Syndrome by Xin Tao, Katilynne Croom, Adrian Newman-Tancredi, Mark Varney, Khaleel A. Razak

“…Consistent with findings in FXS human studies, the mouse model of FXS, the Fmr1 knock out (KO) mouse, shows auditory hypersensitivity and temporal processing deficits. …”
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RSM-Based Optimization of the Parameters Affecting TiO2-Mediated UV Photocatalysis of Vehicular Emissions in Enclosed Parking Garages by Sandeep Singh, Parteek Thind, Manpreet Kaur Verma, Dapinder Deep Singh, Arjun Sareen, Dheeraj Ahuja, Jasgurpreet Singh Chohan, Raman Kumar, Shubham Sharma, Nima Khalilpoor, Alibek Issakhov

“…Subsequently, exposure of humans to these accumulated pollutants is also expected to degrade their health. …”
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Portable X-ray fluorescence of zinc and selenium with nail clippings-Mother and Infant Nutrition Investigation (MINI). by David E B Fleming, Nelly Madani, Michaela G Kaiser, Jong Sung Kim, Erin Keltie, Natashia Drage, Ying Jin, Jane Coad, Louise Brough

“…Zinc and selenium are essential minerals for human nutrition. Reliable biomarkers of zinc status and selenium status in humans are therefore important. …”
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Fractional-order PID feedback synthesis controller including some external influences on insulin and glucose monitoring by Kottakkaran Sooppy Nisar, Muhammad Farman, Khadija Jamil, Saba Jamil, Evren Hincal

“…The article aims to develop a fractional-order proportional integral derivative (PID) controller to monitor insulin and glucose levels in humans under the influences of stress, excitement, and trauma. …”
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Health risk assessment and microplastic pollution in streams through accumulation and interaction by heavy metals by A.M. Sabilillah, F.R. Palupi, B.K. Adji, A.P. Nugroho

“…BACKGROUND AND OBJECTIVES: The threat posed by microplastics to humans through fish consumption is potentially great due to microplastics’ capacity to adsorb heavy metals. …”
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Silver (Ag) doped graphitic carbon nitride (g-C3N4)/biochar composite photocatalyst for improved photocatalytic degradation of ciprofloxacin (CIP) by Ijlal Idrees, Muhammad Zafar, Malik Adeel Umer, Fahad Rehman, Abdul Razzaq, Seongwan Kim, Yunsook Yang, Woo Young Kim

“…Dumping pharmaceutical wastewater into aquatic bodies vigorously adds to environmental pollution and amplifies antibiotic-resilient bacteria (ARB), a potential danger to humans and living organisms. Among several wastewater treatment methods, the photocatalysis approach under the umbrella of advanced oxidation processes (AOPs) offers a sustainable, inexpensive, and comprehensive treatment of emerging pharmaceutical pollutants (PEPs). …”
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A Genome-Wide Analysis of Long Noncoding RNAs in Circulating Leukocytes and Their Differential Expression in Type 1 Diabetes Patients by Yihan Liu, Xiaoming Du, Jia Cui, Changlong Li, Meng Guo, Jianyi Lv, Xin Liu, Jingtao Dou, Xiaoyan Du, Hongjuan Fang, Zhenwen Chen

“…Further analysis showed that 61.28% of the novel lncRNAs were conserved in humans. A set of 12 lncRNAs were selected for qPCR validation, and 9 of 12 lncRNAs were confirmed to show significant differential expression between the T1D and control validation cohorts. …”
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PWWP domain-containing protein Crf4-3 specifically modulates fungal azole susceptibility by regulating sterol C-14 demethylase ERG11 by Pengju Yu, Shuting Ye, Mi Zhou, Long Zhang, Zhongchi Zhang, Xianyun Sun, Shaojie Li, Chengcheng Hu

“…Considering research on small molecules targeting the PWWP domain in humans, Crf4-3 homolog emerges as a promising target for designing fungal-specific drugs to combat azole resistance.…”
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Epidemiological and genetic charateristics of Vibrio vulnificus from diverse sources in China during 2012–2023 by Dongling Long, Min Li, Lingchao Ma, Jiewen Huang, Chao Lv, Yiwen Chen, Zile Cheng, Chang Liu, Huitao Huang, Xiaokui Guo, Chao Yang, Yongzhang Zhu

“…Abstract Vibrio vulnificus is a significant zoonotic pathogen that causes severe vibriosis in humans and fish. The lack of a national annual surveillance program in China has hindered understanding of its epidemiological characteristics and genetic diversity. …”
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Normative Values of Brainstem Auditory-Evoked Responses in Sheep by Katharina Suntinger, Adrian Dalbert, Lukas Prochazka, Milena Tegelkamp, Peter Kronen, Karina Klein, Christof Röösli, Alexander Huber, Flurin Pfiffner

“…<b>Conclusions:</b> The normative values for sheep BAERs were reproducible and similar to those of humans. The normative BAER values further support sheep as an adequate animal model for otological research.…”
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Effects of systemic administration of the retinoid Isotretinoin on bone tissue: A narrative literature review by Maria Júlia Bento Martins Parreira, Bruna Trazzi Pagani, Matheus Bento Medeiros Moscatel, Daniela Vieira Buchaim, Carlos Henrique Bertoni Reis, Beatriz Flávia de Moraes Trazzi, Acácio Fuziy, Rogerio Leone Buchaim

“…After analyzing the selected articles, it was possible to observe several reports on hyperostosis or even changes in the formation of bone structures in human patients. Concerning animals, the largest number of studies addressed the changes caused in the formation or development of bone structures by the systemic administration of Isotretinoin. …”
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Level of physical activity of students from the police force academy in Bratislava by Gabriel Bujdos, Štefan Adamčák, Michal Marko, Anna Kozaňáková

“…Being more physically active has never been more important than today as both jobs and leisure activities are becoming increasingly sedentary. Humans have moved from being very physically active to being less and less active each year. …”
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Systematic literature review on Calcium Pyrophosphate Deposition (CPPD) nomenclature: condition elements and clinical states— A Gout, Hyperuricaemia and Crystal-Associated Disease... by Georgios Filippou, Antonella Adinolfi, Emilio Filippucci, Nicola Dalbeth, Robert Terkeltaub, Tristan Pascart, Edoardo Cipolletta, Silvia Sirotti, Charlotte Jauffret, Sara Tedeschi, Daniele Cirillo, Luca Ingrao, Alessandro Lucia

“…This systematic literature review constituted its first step and aimed to provide a state-of-the-art analysis of the medical literature of the last 20 years.Methods A systematic literature search was undertaken in the PubMed, Cochrane and Embase databases between 2000 and 2022, restricted to studies on humans and in the English language. Eight reviewers independently and manually extracted labels related to CPPD concepts, according to an a priori list generated by the authors: pathogenic conditions and pathogenic crystal labels, elementary imaging condition elements and asymptomatic and symptomatic condition states. …”
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Evaluation of the Knowledge, Attitudes and Practice of Veterinary Professionals and Senior Animal Health Students in Central Gondar Zone, Gondar, Ethiopia: Antimicrobial Use and Re... by Abibo Wondie Mekonen, Yesuneh Tefera Mekasha, Melaku Getahun Feleke, Atsede Getaneh, Meron Dereje, Misganew Bafe, Sete Nigussie, Achenef Melaku Beyene

“…ABSTRACT Background Antimicrobial resistance (AMR) poses a worldwide challenge to the well‐being of animals and humans. The emergence of AMR is largely attributed to the improper utilization and overuse of antimicrobials. …”
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Microplastic polymers in shellfish and fish in the coastal area by S. Basri K., A. Daud, A.B. Birawida, M. Maming, H.J. Mukono, D.S. Arsyad

“…These findings indicate that marine organisms and humans are exposed to microplastics, which are potentially harmful, but further research is needed to understand the full extent of the associated environmental health impacts and risks.…”
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