Fibroblasts in rheumatoid arthritis: novel roles in joint inflammation and beyond by Elpida Neofotistou-Themeli, Elpida Neofotistou-Themeli, Panagiota Goutakoli, Panagiota Goutakoli, Theodoros Chanis, Theodoros Chanis, Maria Semitekolou, Maria Semitekolou, Eirini Sevdali, Eirini Sevdali, Prodromos Sidiropoulos, Prodromos Sidiropoulos

“…High-throughput technologies in human and animal studies have revealed novel molecular and cellular pathways involved in tissue inflammation of rheumatoid arthritis (RA). …”
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Remote and Anesthetic-Induced Myocardial Preconditioning Is Preserved in Atherosclerotic LDL Receptor-/- Mice In Vivo by Walter Petermichl, Kathrin Eglmeier, Henriette Hesse, Michael Gruber, Bernhard Graf, Andre Bredthauer, Andreas Redel

“…In the animal model, preconditioning is a powerful weapon against ischemic damage. The reason why the human heart cannot be protected from ischemic damage by preconditioning remains unclear. …”
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A multi-channel bioimpedance-based device for Vietnamese hand gesture recognition by Nhat-Minh Than, Son-Thuy Nguyen, Dang-Nguyen Huynh, Thao-Nguyen Tran, Nguyen-Khoa Le, Huu-Xuan Mai, Cao-Dang Le, Tan-Thi Pham, Quang-Linh Huynh, Trung-Hau Nguyen

“…The promising results lay a foundation for future developments in nonverbal communication between humans and machines as it contributes to the advancement of technology for the benefit of individuals with hearing impairments, addressing a critical social need.…”
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Deciphering of differences in gut microbiota and plasma metabolites profile between non-obese and obese Golden Retrievers dogs by Yazhen Cai, Huayu Tang, Guilin Xiang, Hongyu Yi, Jie Zhong, Zhaoxi Xie, Qinfeng Hu, Romaissaa El Bouhi, Pan Zhou, Yong Zhang, Honglin Yan

“…Microbial and metabolite biomarkers have been proposed for identifying the presence of obesity in humans and rodents. However, the effects of obesity on the microbiome and metabolome of Golden Retrievers remains unknown. …”
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Electromagnetic metamaterial agent by Shengguo Hu, Mingyi Li, Jiawen Xu, Hongrui Zhang, Shanghang Zhang, Tie Jun Cui, Philipp del Hougne, Lianlin Li

“…In response to live environmental feedback within a real-world setting emulating an ambient-assisted living context (including human requests in natural language), our metaAgent prototype self-organizes a hierarchy of EM manipulation tasks in conjunction with commanding a robot. metaAgent masters foundational EM manipulation skills related to wireless communications and sensing, and it memorizes and learns from past experience based on human feedback.…”
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Experimental study of mortar incorporating nano-magnetite on engineering performance and radiation shielding by Kunchariyakun Kittipong, Sinyoung Suthatip, MacKenzie Kenneth J. D., Pungkun Vithit, Raknarong Pakkamai, Teh Musofpar, Jekabaso Afham, Sittichan Narumol

“…These results indicate that the addition of nano-Fe3O4 to radiation-shielding mortar can potentially attenuate gamma rays rather than neutrons and lead to the development of materials for shielding radiation from radioactive storage facilities, thereby reducing the impact of this hazardous waste on humans and the environment.…”
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IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2 by Rong Xu, Hong-Fan Sun, David W. Williams, Adam V. Jones, Ali Al-Hussaini, Bing Song, Xiao-Qing Wei

“…Candida albicans is a fungus that is an opportunistic pathogen of humans. Normally, C. albicans exists as a harmless commensal and does not trigger inflammatory responses by resident macrophages in skin mucosa, which may be caused by a tolerance of skin macrophage to C. albicans. …”
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High Seropositivity of Brucella melitensis Antibodies among Pregnant Women Attending Health Care Facilities in Mwanza, Tanzania: A Cross-Sectional Study by Helmut A. Nyawale, Michael Simchimba, Joseph Mlekwa, Fridolin Mujuni, Elieza Chibwe, Prosper Shayo, Elifuraha B. Mngumi, Khadija S. Majid, Mtebe Majigo, Stephen E. Mshana, Mariam M. Mirambo

“…Brucella melitensis (B. melitensis), the most pathogenic species is responsible for several pregnancy adverse outcomes in both humans and animals. Here, we present the data on the magnitude of B. melitensis antibodies among pregnant women in Mwanza, Tanzania, the information that might be useful in understanding the epidemiology of the disease and devising appropriate control interventions in this region. …”
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Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization by Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask, Paul de Vos, Corinne A Hoesli

“…So far, the results have been less promising when transitioning to humans and larger animal models due to challenges in oxygenation and insulin delivery. …”
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Anthelmintic activity of 1,10-phenanthroline-5,6-dione-based metallodrugs by Maria E. Cirino, Thainá R. Teixeira, Alessandro M. H. Silva, Ana C. C. Borges, Lucas Fukui-Silva, Luis G. Wagner, Christiane Fernandes, Malachy McCann, André L. S. Santos, Josué de Moraes

“…This study investigates the potential antiparasitic activity of 1,10-phenanthroline-5,6-dione (phendione) and its metal complexes, [Cu(phendione)3](ClO4)2.8H2O and [Ag(phendione)2](ClO4), against Schistosoma mansoni, the causative agent of intestinal schistosomiasis, and Angiostrongylus cantonensis, responsible for eosinophilic meningitis in humans. Additionally, the compounds were tested on Caenorhabditis elegans, a model organism for drug discovery. …”
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Nonhuman primate antigenic cartography of SARS-CoV-2 by Annika Rössler, Antonia Netzl, Ninaad Lasrado, Jayeshbhai Chaudhari, Barbara Mühlemann, Samuel H. Wilks, Janine Kimpel, Derek J. Smith, Dan H. Barouch

“…In addition, substantial concordance was observed between our NHP-derived and two human antigenic maps, demonstrating the utility of NHPs as a surrogate for antigenic cartography in humans.…”
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Measurement the Physiological Properties of Water Pipe Smokers in Shekhan Distract by Abdullah. M. Al-Saiegh, Turki Sabri Haji, Jihan Saado Ahmed, Alaa Azzo Aslo, Firas Faris Khalaf

“…Smoking is one of the old habits used by humans before 400 years ago, where this custom was exclusively used in males with the development of time, tools, ingredients and flavors that used in hookah the women also started smoking, which led to an increase in the prevalence of use in many countries of the world Smoking is one of the reasons that lead to an increase in the percentage incidence of lung cancer, chronic lung disease ,mouth disease ,teeth deformation and gingivitis. …”
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Chemical, Spectral, Biological, and Toxicological Studies of Some Benzene Derivatives Used in Pharmaceuticals: In Silico Approach by Emranul Kabir, M R O Khan Noyon, Md Rabiul Alam, Mr. Nasiruddin, Sajia Islam, Mahima Akter, Monir Uzzaman

“… The immune system of humans is impacted by many drugs. Chemicals that have a gender-bending impact on boys, were synthesized, their use spread, and as a consequence, they entered the ecology, the food chain, and eventually ended up in blood or human breast milk. …”
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Basal Cell Carcinoma Diagnosed by Dermoscopy in Dermatology Clinic of the Miguel Enríquez University Hospital by Delia María Gálvez Medina, Yurelbis Loida Lobaina Mejías, Juliette Massip Nicot, Lisbeth Fernández González, Carmen Oraida Tenorio Morión, Dayné Leyva Duthil

“…<strong>Foundation:</strong> basal cell carcinoma is a very common malignant tumor in humans. It is considered locally invasive, also aggressive and destructive. …”
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Editorial by Michael Rose, Jonathan M. Hoffmann

“…Second, Melissa Ihlow and Maria Lenk (Stuttgart) review “Humans in the Global Ecosystem”, edited by Pierre L. …”
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First Detection of <i>Alphacoronavirus</i> in Bats from the World’s Largest Wetland, the Pantanal, Brazil by Tayane B. S. Magalhães, Amanda de O. Viana, Thiago B. F. Semedo, Juliane S. Saldanha, Nicole A. dos Reis, Nathalia de A. Pereira, Rachel V. P. de Barros, Hannah R. Miranda, Gabriella C. Almeida, Desyrée Y. S. R. Ozaki, Giovana S. Caleiro, Gustavo O. Fenner, Fernanda P. Vizu, Theo Kraiser, Thais P. Carvalho, Luciano M. Thomazelli, Erick G. Dorlass, Clarice W. Arns, Helena L. Ferreira, Erika Hingst-Zaher, Rogério Vieira Rossi, Guilherme S. T. Garbino, Edison L. Durigon, Jansen de Araujo, Daniel M. de Aguiar

“…Coronaviruses (CoV) infect a wide variety of hosts, causing epidemics in humans, birds, and mammals over the years. Bats (order Chiroptera) are one of the natural hosts of the Coronaviridae family. …”
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Epidemiology and Ecology of Toscana Virus Infection and Its Global Risk Distribution by Xue-Geng Hong, Mei-Qi Zhang, Fang Tang, Si-Hui Song, Jia-Yi Wang, Zhen-Yu Hu, Li-Ming Liu, Xiao-Ai Zhang, Yi Sun, Li-Qun Fang, Wei Liu

“…The potential geographic distribution and risk to the human population remained obscure due to its neglected nature. …”
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The Prevalence of Enteric Viruses in Bivalve Molluscs in a Farming Area in Liguria, Northwest Italy by Chiara Masotti, Laura Serracca, Erica Costa, Barbara Betti, Aitor Garcia-Vozmediano, Elisabetta Suffredini, Roberta Battistini

“…Bivalve molluscs are filter-feeding organisms, capable of concentrating pathogenic microorganisms from the surrounding environment, thus contributing to the spread of viral pathogens, which they can transmit to humans, especially if eaten raw or undercooked. Although norovirus (NoV) and the hepatitis A virus (HAV) are considered the most common causes of foodborne infections, in recent years, other viruses with a zoonotic potential have been identified in shellfish, such as the hepatitis E virus (HEV), astrovirus (AsV), and aichi virus (AiV). …”
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Metabolic profile of blood serum in experimental arterial hypertension by A. A. Seryapina, A. A. Malyavko, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, A. L. Markel

“…The pathogenesis of hypertension is influenced by a variety of both genetic and environmental factors, which determines the heterogeneity of the disease in human population. Hence, there is a need to perform research on experimental models – inbred animal strains, one of them being ISIAH rat strain, which is designed to simulate inherited stress-induced arterial hypertension as close as possible to primary (or essential) hypertension in humans. …”
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Lactobacillus acidophilus alleviate Salmonella enterica Serovar Typhimurium-induced murine inflammatory/oxidative responses via the p62-Keap1-Nrf2 signaling pathway and cecal micro... by Haihua Li, Xinyi Ma, Zhiyuan Shang, Xuejiao Liu, Jiayun Qiao

“…Typhimurium) infection can cause inflammation and oxidative stress in the body, leading to gastroenteritis, fever and other diseases in humans and animals. More and more studies have emphasized the broad prospects of probiotics in improving inflammation and oxidative stress, but the ability and mechanism of Lactobacillus acidophilus (LA) to alleviate the inflammatory/oxidative reaction caused by pathogens are still unclear.Methods and resultsIn this study, we treated the mice with LA for 14 days, infected them with S. …”
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