Immunopathological Changes of Streptococcus pneumoniae Causing Respiratory Infection in Lambs by Abbas A Hamzah, Zainab I Ibrahim

“… Streptococcus pneumoniae are common bacterial pathogens that can cause a range of diseases in humans and animals. This study attempts to clarify the course and consequences of pneumonia caused by this bacterial infection. …”
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An evaluation of osseous regeneration capability of novel autogenous tooth graft along with orthobiologics for long bone segmental defects by N. Hussain, M.A. Khan, A.K. Mahmood, M.Y. Tipu, S. Aslam

“…Though usage of aforementioned regimens in-vivo needs further trials but overall, we may suggest that autogenous tooth is not only a novel and viable graft in solo but its healing capacity, osteointegration and firm callus formation can be augmented with appropriate orthobiologic materials and in future may be useful for bone defect treatments, not only in animals but humans as well.…”
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Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind, Placebo-Controlled Cli... by Biljana Lakić, Ranko Škrbić, Snežana Uletilović, Nebojša Mandić-Kovačević, Milkica Grabež, Mirna Popović Šarić, Miloš P. Stojiljković, Ivan Soldatović, Zorica Janjetović, Anastasija Stokanović, Nataša Stojaković, Momir Mikov

“…Ursodeoxycholic acid (UDCA), as the first BA used in humans, improves glucose and lipid metabolism and attenuates oxidative stress. …”
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Host Susceptibility to Brucella abortus Infection Is More Pronounced in IFN-γ knockout than IL-12/β2-Microglobulin Double-Deficient Mice by Ana Paula M. S. Brandão, Fernanda S. Oliveira, Natalia B. Carvalho, Leda Q. Vieira, Vasco Azevedo, Gilson C. Macedo, Sergio C. Oliveira

“…Brucella abortus is a facultative intracellular bacterial pathogen that causes abortion in domestic animals and undulant fever in humans. IFN-γ, IL-12, and CD8+ T lymphocytes are important components of host immune responses against B. abortus. …”
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Isolation, Characterization, and Quantification of Bacteria from African Sausages Sold in Nairobi County, Kenya by W. H. Karoki, D. N. Karanja, L. C. Bebora, L. W. Njagi

“…This study has demonstrated presence of bacteria in African sausages which are potentially zoonotic to humans. Comprehensive study is needed to sample more eatery meat points in Nairobi and other areas in order to demonstrate pathogenic attributes of these isolates and establish the respective total aerobic bacterial count. …”
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Investigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis by Weilong Tu, Hongyang Wang, Yingying Zhang, Ji Huang, Yuduan Diao, Jieke Zhou, Yongsong Tan, Xin Li

“…Asthma has been extensively studied in humans and animals, but the molecular mechanisms underlying asthma in Meishan pigs, a breed with distinct genetic and physiological characteristics, remain elusive. …”
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Impact of standard and long-lasting ivermectin formulations in cattle and buffalo on wild Anopheles survival on Sumba Island, Indonesia by Kevin C. Kobylinski, Tri B. T. Satoto, Wisnu Nurcahyo, Yudi Ratna Nugraheni, Vincentius A. Testamenti, I Putu B. A. Winata, Yosua L. Pono, Diana Timoria, Piyanan Assawasuwannakit, Mary Chambers, J. Kevin Baird, Joel Tarning, Lorenz von Seidlein, Claus Bøgh

“…Of the four hosts evaluated buffalo were the most attractive to Anopheles followed by cattle then horse and finally humans. This study demonstrates, for the first time, the superiority of a commercially available long-lasting ivermectin formulation for the potential deployment of mass ivermectin treatment of livestock as a vector control tool for malaria elimination in Southeast Asia.…”
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Techno-structural and 3-D geometric morphometric analysis applied for investigating the variability of Holocene unifacial tools in tropical Central Brazil. by Marina González-Varas, Antoine Lourdeau, Letícia Gonçalves, Rafael Lemos de Souza, Diego Teixeira Mendes, Tatyana Beltrão de Oliveira, Gustavo Furlaneto Silva, Hubert Forestier, Rolando Romero, Antonio Pérez-Balarezo

“…However, the factors influencing their morphological and structural variability remain largely unexplored, obscuring our understanding of their ergonomics and their role as mediators between humans and tropical environments. This study hypothesizes that the variability observed within and among unifacial tools from the GO-Ni sites in Central Brazil is a result of a combination of factors, including raw material availability and functional and ergonomic requirements. …”
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Eco-anthropologie et primatologie pour la conservation de la biodiversité : un projet collaboratif dans le Parc National de Moukalaba-Doudou, Gabon by Naoki Matsuura, Yuji Takenoshita, Juichi Yamagiwa

“…Among these, African great apes are especially vulnerable because of their long life cycle and low reproduction rates, large range size, and high risk of being infected by diseases of human origin. Thus, conservation of biodiversity in African tropical rainforest, especially of great apes, is an urgent problem. …”
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Characteristic Fe and Cu Compounds in Particulate Matter from Subway Premises in Japan and their Potential Biological Effects by Takuma Okamoto, Ayumi Iwata, Hiroko Yamanaka, Kako Ogane, Tatsuhiro Mori, Akiko Honda, Hirohisa Takano, Tomoaki Okuda

“…The potential biological effects of these chemical states on humans were also investigated in vitro by assessing cell damage and its pathways in cells after exposure to several compounds. …”
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Safety assessment of the substance 2,2′‐oxydiethylamine for use in plastic food contact materials by EFSA Panel on Food Contact Materials (FCM), Claude Lambré, Riccardo Crebelli, Maria deSilva, Konrad Grob, Evgenia Lampi, Maria Rosaria Milana, Marja Pronk, Mario Ščetar, Georgios Theodoridis, Els Van Hoeck, Nadia Waegeneers, Claudia Bolognesi, Ronan Cariou, Laurence Castle, Emma Di Consiglio, Roland Franz, Eric Barthélémy, Remigio Marano, Gilles Rivière

“…Based on their physico‐chemical properties and experimental data, the Panel considered the potential for accumulation in humans of the oligomers containing the substance of no concern. …”
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Identifying the snake: First scoping review on practices of communities and healthcare providers confronted with snakebite across the world. by Isabelle Bolon, Andrew M Durso, Sara Botero Mesa, Nicolas Ray, Gabriel Alcoba, François Chappuis, Rafael Ruiz de Castañeda

“…<h4>Methods</h4>Epidemiological studies of snakebite in humans that provide information on biting snake identification were systematically searched in Web of Science and Pubmed from inception to 2nd February 2019. …”
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Effect of epigallocatechin-3-gallate (EGCG) on cognitive functioning and the expression of APP and BDNF in the hippocampus of rats with streptozotocin -induced Alzheimer-like disea... by Farnaz Ghayour Babaei, Ehsan Saburi, Fatemeh Forouzanfar, Mohadese Asgari, Zakieh Keshavarzi, Vahid Hajali

“…These findings could provide a beneficial insight for developing novel, safe, and efficient natural compounds for preventing or alleviation AD symptoms in humans.…”
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Global Assessment of Emerging Contaminant Removal in Wastewater Treatment Plants: <i>In Silico</i> Hazard Screening and Risk Evaluation by Arianna Sgariboldi, Elena Posté, Nicola Chirico, Alessandro Sangion, Marco Evangelista, Cristiana Morosini, Andrea Re, Vincenzo Torretta, Ester Papa

“…Pharmaceuticals and personal care products (PPCPs) are emerging contaminants (ECs), whose presence in the environment is of increasing concern due to their widespread use and possible detrimental effects on wildlife and humans. These chemicals may present multiple hazardous properties such as environmental persistence, toxicity, high mobility, and the potential for bioaccumulation. …”
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Rapid microcystin-LR detection using antibody-based electrochemical biosensors with a simplified calibration curve approach by Samuel Adjei-Nimoh, Lance-Nicolas Rances, Maha A. Tony, Hossam A. Nabwey, Woo Hyoung Lee

“…Abstract Harmful algal blooms (HABs) can release cyanotoxins such as microcystins (MCs), especially, microcystin-leucine-arginine (MC-LR) which is one of the commonest and most toxic, into our water bodies and can lead to several acute or chronic diseases such as liver diseases and respiratory irritation in humans. There is an increasing need for rapid and simple detection of MC-LR in water bodies for early warning of HABs. …”
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Impact of Comorbidities on the Severity of Disease & Outcome in Children with COVID 19 at a Tertiary Care Pediatric Hospital, Rawalpindi. by Rai Muhammad Asghar, Muddassar Sharif, Khalid Saheel, Isfandyar Khan, Abid Hussain, Rai Rijjal Ashraf

“…The virus affects almost all countries of the world. It has infected humans in all age groups, of all ethnicities, both males and females. …”
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A mouse model of deep vein thrombosis by inferior vena cava hypoperfusion using ameroid constrictors by Hiroko Tadokoro, Yukihide Ota, Mari Uomoto, Shiro Koizume, Shinya Sato, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Yoko Endo-Takahashi, Yoichi Negishi, Etsuko Miyagi, Yohei Miyagi

“…Compared with thrombi on day 3 post-AC implantation, those on day 8 showed characteristics of human thrombi in the subacute to chronic stage. The BF in the IVC was maintained even on day 8. …”
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Progenitor Cells for Arterial Repair: Incremental Advancements towards Therapeutic Reality by Trevor Simard, Richard G. Jung, Pouya Motazedian, Pietro Di Santo, F. Daniel Ramirez, Juan J. Russo, Alisha Labinaz, Altayyeb Yousef, Brijesh Anantharam, Ali Pourdjabbar, Benjamin Hibbert

“…Circulating EPC numbers have been inversely correlated with cardiovascular risk, while administration of EPCs in humans has demonstrated improved clinical outcomes. …”
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Serological Survey and Factors Associated with Toxoplasma gondii Infection in Domestic Goats in Myanmar by Saw Bawm, Wint Yi Maung, Myat Yee Win, May June Thu, Hla Myet Chel, Tin Aye Khaing, Soe Soe Wai, Lat Lat Htun, Tin Tin Myaing, Saruda Tiwananthagorn, Makoto Igarashi, Ken Katakura

“…However, infection of goats with Toxoplasma gondii could be a source of parasite transmission to humans. The information on T. gondii infection of goat was not reported yet in Myanmar. …”
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tRF-AspGTC Promotes Intracranial Aneurysm Formation by Controlling TRIM29-Mediated Galectin-3 Ubiquitination by Chao Wang, Bing Yu, Han Zhou, Huanting Li, Shifang Li, Xiaolu Li, Wentao Wang, Yugong Feng, Tao Yu

“…In this study, we identified that the transfer RNA-Asp-GTC derived fragment (tRF-AspGTC) is highly expressed in the IA tissues of both humans and mice. tRF-AspGTC promotes IA formation by facilitating the phenotypic switching of vascular smooth muscle cells, increasing of matrix metalloproteinase 9 expression, and inducing of oxidative stress and inflammatory responses. …”
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