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10501
PET imaging of AAV9 and AAVBR1 trafficking in normal mice
Published 2025-02-01“…Abstract Adeno-associated virus (AAV) mediated gene therapy is advancing and needs a noninvasive imaging tool to evaluate its effective targeting, biodistribution and clearance for precise use in humans. In this study, two serotypes of AAVs, AAV9-CMV-fLuc, and a brain targeting variant, AAVBR1-CMV-fLuc, are directly radiolabeled with the positron emission tomography (PET) radioisotope, 89Zr. …”
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10502
Structural Characterization of Functional Ingredient Levan Synthesized by Bacillus siamensis Isolated from Traditional Fermented Food in Thailand
Published 2020-01-01“…One beneficial food to humans of known nutritional value is the prebiotic levan. …”
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10503
Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent
Published 2014-01-01“…A new acellular plague vaccine composed of two separate recombinant proteins (rF1 and rV) has been developed and assessed for immunogenicity in humans. Using serum obtained from human volunteers immunised with various doses of this vaccine and from immunised cynomolgus macaques, we assessed the pharmacokinetic properties of human and cynomolgus macaque IgG in BALB/c and the NIH Swiss derived Hsd:NIHS mice, respectively. …”
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10504
Microbial Isolates from Vegetable Foreign Bodies Inhaled by Dogs
Published 2018-01-01“…These data are relevant in relation to the use of these antibiotics in both animals and humans, for the risk of transmission of antibiotic resistant bacteria or resistance genes.…”
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10505
Copper in the colorectal cancer microenvironment: pioneering a new era of cuproptosis-based therapy
Published 2025-01-01“…Copper, an essential trace element and biochemical cofactor in humans plays a critical role in maintaining health. …”
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10506
Scoping Review of the Zika Virus Literature.
Published 2016-01-01“…Several knowledge gaps were identified by this review with respect to ZIKV epidemiology, the importance of potential non-human primates and other hosts in the transmission cycle, the burden of disease in humans, and complications related to human infection with ZIKV. …”
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10507
Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes
Published 2015-01-01“…The ZDSD rat develops prediabetic metabolic syndrome and T2D in a manner that mirrors the development of metabolic syndrome and T2D in humans. ZDSD rats will provide a novel, translational animal model for the study of human metabolic diseases and for the development of new therapies.…”
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10508
Orientia, Rickettsia, and the microbiome in rodent attached chiggers in North Carolina, USA.
Published 2024-01-01“…Further research is required to determine if the potential pathogens found detected in chiggers are a threat to humans and wildlife.…”
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10509
The systemic immune state of super-shedder mice is characterized by a unique neutrophil-dependent blunting of TH1 responses.
Published 2013-01-01“…In this study, we used the model organism Salmonella enterica serovar Typhimurium, an important cause of disease in humans and animal hosts, to study the immune state of super-shedders. …”
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10510
Toxicopathological Effects of the Venom of Echis ocellatus on Experimentally Envenomated Swiss Albino Rats
Published 2024-12-01“…The significance of Echis ocellatus in causing envenomation in humans and animals in Northern Nigeria has been widely recognized, with experts identifying it as the most medically important snake in the region. …”
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10511
Optical Coherence Tomography
Published 2007-01-01“…OCT imaging from the gastrointestinal tract can be done in humans by using narrow-diameter, catheter-based probes that can be inserted through the accessory channel of either a conventional front-view endoscope, for investigating the epithelial structure of the gastrointestinal tract, or a side-view endoscope, inside a standard transparent ERCP (endoscopic retrograde cholangiopancreatography) catheter, for investigating the pancreatico-biliary ductal system. …”
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10512
Detection of multidrug resistant Vibrio parahaemolyticus and anti-Vibrio Streptomyces sp. MUM 178J
Published 2023-10-01“…V. parahaemolyticus is transmitted from these marine animals in aquaculture to humans via raw or undercooked seafood, resulting in gastroenteritis outbreaks. …”
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10513
Performance and limitations of linkage-disequilibrium-based methods for inferring the genomic landscape of recombination and detecting hotspots: a simulation study
Published 2023-03-01“…We thus address a message of caution for the users of these approaches, at least for genomes with complex recombination landscapes such as in humans. …”
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10514
Mathematical Modeling of a Quasi-passive Dynamic Walker with Whole-body Tensile Connections
Published 2025-01-01“…Humans have whole-body viscoelastic connections called anatomy trains (ATs), which include multiple muscles and connective tissues. …”
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10515
Mining the Proteome of subsp. ATCC 25586 for Potential Therapeutics Discovery: An Approach
Published 2016-12-01“…In this study, we adopted subtractive genomics approach to analyze the whole genome sequence of the Fusobacterium nucleatum, a human oral pathogen having association with colorectal cancer. …”
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10516
Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies
Published 2016-01-01“…Positivity to anti-MAP and homologous human peptides was detected in 48% of at-risk subjects compared to 5,85% HCs, preceding appearance of islet autoantibodies. …”
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10517
Freestanding VO2 membranes on epidermal nanomesh for ultra-sensitive correlated breathable sensors
Published 2025-02-01“…The resistance of the VO2 membranes is reversibly tuned by human’s tiny mechanical stimuli and breath stimuli. …”
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10518
Semantic analysis of test items through large language model embeddings predicts a-priori factorial structure of personality tests
Published 2025-01-01“…Our results indicate that LLM-derived embeddings can effectively capture semantic similarities among test items, showing moderate to high correlation with the factorial structure produced by humans respondents in all tests, potentially serving as a valid measure of content validity for initial survey design and refinement. …”
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10519
Recent advances in applications of green nanocomposites in enhanced oil recovery: a comprehensive review of different characterization methods and effective parameters
Published 2025-01-01“…These substances are non-toxic, safe for humans, and harmless to other living things. Common investigations like XRD, FTIR spectroscopy, SEM, and Zeta Potential tests are used to detect and evaluate nanoparticles. …”
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10520
V's Virtual Afterlife
Published 2025-01-01“… Nonhuman Online Personas (NHOPs) are coherent digital assemblages not directly associated with the identities of individual humans. NHOPs encompass entities like brands, places, artificial intelligences, and, as we explore in this study, video game characters. …”
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