Toxicity of Low-dose Graphene Oxide Nanoparticles in an in-vivo Wild Type of Caenorhabditis elegans Model by Ming-Hsien Tsai, How-Ran Chao, Jheng-Jie Jiang, Yu-Hsieh Su, Mariene-syne P. Cortez, Lemmuel L. Tayo, I-Cheng Lu, Hao Hsieh, Chih-Chung Lin, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang, Wen-Li Hsu

“…Abstract Carbon-based engineered nanomaterials, such as graphene oxide nanoparticles (GO NPs), are widely available for application, but their potentially adverse health effects on humans still require investigation. In this study, the environmental levels of GO NPs are addressed to examine whether GO leads to adverse effects on an in-vivo model of Caenorhabditis elegans (C. elegans). …”
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Larvicidal Effectiveness of Azolla pinnata against Aedes aegypti (Diptera: Culicidae) with Its Effects on Larval Morphology and Visualization of Behavioural Response by Nor Shaida Husna Zulkrnin, Nurul Nadiah Rozhan, Nur Amanina Zulkfili, Nik Raihan Nik Yusoff, Mohd Sukhairi Mat Rasat, Nor Hakimin Abdullah, Muhammad Iqbal Ahmad, Rajiv Ravi, Intan H. Ishak, Mohamad Faiz Mohd Amin

“…(Diptera: Culicidae) is a primary vector for dengue viral infections for humans. Current focus on application of natural product against mosquito vectors has been the main priority for research due to its eco-safety. …”
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Curcumin dietary supplementation enhances serum carbohydrate-degrading enzyme activities in buffaloes by Maima Matin, Natalia Ksepka, Kamil Wysocki, Michel-Edwar Mickael, Alpana Pande, Jarosław Olav Horbańczuk, Artur Jóźwik, Olga Adamska, Artur Stolarczyk, Laszlo Barna Iantovics, Yordanka Ilieva, Pencho Penchev, Atanas G. Atanasov

“…Previous studies have investigated metabolic effects of curcumin in humans or established animal research models such as mice, but studies with farm animals have been scarce. …”
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Women Are More Susceptible to Caries but Individuals Born with Clefts Are Not by Aditi Jindal, Michelle McMeans, Somnya Narayanan, Erin K. Rose, Shilpa Jain, Mary L. Marazita, Renato Menezes, Ariadne Letra, Flavia M. Carvalho, Carla A. Brandon, Judith M. Resick, Juan C. Mereb, Fernando A. Poletta, Jorge S. Lopez-Camelo, Eduardo E. Castilla, Iêda M. Orioli, Alexandre R. Vieira

“…Isolated forms of cleft lip and palate are among the most common craniofacial congenital anomalies in humans. Historically, several reports suggest that individuals born with clefts have a higher risk for caries. …”
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Peringkasan Artikel Berbahasa Indonesia Menggunakan TextRank dengan Pembobotan BM25 by Yurdha Fadhila Hernawan, Putra Pandu Adikara, Randy Cahya Wihandika

“…Abstract The use of the internet as a source of information has brought humans to a oneclick era. Anything can be accessed anywhere, visually or not. …”
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Antibiotic and Disinfectant Susceptibility Patterns of Bacteria Isolated from Farmed Fish in Kirinyaga County, Kenya by Daniel W. Wanja, Paul G. Mbuthia, Robert M. Waruiru, Lilly C. Bebora, Helena A. Ngowi, Philip N. Nyaga

“…The resistant bacteria may transmit resistance genes to other fish bacteria and also to human bacteria, thus making it difficult to treat the resultant disease(s); thus, there is a possibility that these resistant bacteria may be transmitted to humans who consume or handle the carrier fish. …”
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The potential endocrine-disrupting of fluorinated pesticides and molecular mechanism of EDPs in cell models by Yalan Liu, Fengzhong Wang, Lin Li, Bei Fan, Zhiqiang Kong, Jianxin Tan, Minmin Li

“…The findings will serve as a reference for future studies on the toxicity of pesticides to humans and other organisms.…”
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Revisiting the Metabolism of Donepezil in Rats Using Non-Targeted Metabolomics and Molecular Networking by Eun-Ji Park, Eui-Hyeon Kim, Ki-Young Kim, Ji-Hyeon Jeon, Im-Sook Song, So-Young Park, Kwang-Hyeon Liu

“…<b>Conclusions</b>: The metabolic characteristics of donepezil in rats were comparable to those in humans, indicating that a rat is a reliable model for studying donepezil metabolism. …”
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Phytomedicinal armamentarium: A review of inula racemosa-derived alantolactones and isoalantolactones in anticancer therapy by Joshi Gaurav Santoshrao, Smriti Jamwal, Rakesh Kumar, Ekta Bisht, Bisen Harsh Krishnakumar, Shreya Katoch, R.K. Asrani

“…Future studies should focus on clinical trials to establish their efficacy and safety in humans, paving the way for new cancer therapies.…”
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Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy by Stewart D. Ramsay, Stewart D. Ramsay, Stewart D. Ramsay, Marni A. Nenke, Marni A. Nenke, Emily J. Meyer, Emily J. Meyer, David J. Torpy, David J. Torpy, Richard L. Young, Richard L. Young, Richard L. Young, Richard L. Young

“…The normal inflammatory response to acute infection displays remarkable circadian rhythmicity in humans with increased inflammatory activity during the normal night or rest period. …”
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Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japane... by Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, Kazuo Tsubota, Kaori Hayashi, Jun Yoshino, Hiroshi Itoh

“…Accumulating evidence from both rodents and humans suggests that the levels of nicotinamide adenine dinucleotide (NAD+), a regulator of many biological processes, declines in multiple organs and tissues with aging and obesity. …”
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Evaluation of Biologics ACE2/Ang(1–7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies by Henry Daniell, Geetanjali Wakade, Smruti K. Nair, Rahul Singh, Steven A. Emanuel, Barry Brock, Kenneth B. Margulies

“…This biologic is currently being evaluated in human clinical studies to debulk SARS-CoV-2 in the oral cavity to reduce coronavirus infection/transmission (NCT 0543318). …”
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Two Cases of Lacaziosis in Bottlenose Dolphins (Tursiops truncatus) in Japan by Keiichi Ueda, Ayako Sano, Jyoji Yamate, Eiko Itano Nakagawa, Mitsuru Kuwamura, Takeshi Izawa, Miyuu Tanaka, Yuko Hasegawa, Hiroji Chibana, Yasuharu Izumisawa, Hirokazu Miyahara, Senzo Uchida

“…Lacaziosis, formerly called lobomycosis, caused by Lacazia loboi, is a zoonotic mycosis found in humans and dolphins and is endemic in the countries on the Atlantic Ocean. …”
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Pharmacological regression of atherosclerotic plaque in patients with type 2 diabetes by Loredana Bucciarelli, Daniele Andreini, Giulio Stefanini, Roberta Maria Fiorina, Marco Francone, Federica Catapano, Maria Elena Lunati, Edoardo Conte, Davide Marchetti, Paolo Fiorina

“…Based on animal studies that extend back to the 1920s, regression of atherosclerotic plaques in humans has just started to be considered and pursued. …”
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A Novel Multiplex LAMP Assay for the Rapid and Accurate Diagnosis of Visceral Leishmaniasis Caused by Leishmania infantum from Iran by Sahar Samsami, Sahar Namavari, Saeed Ataei, Abdolmajid Ghasemian, Ava Yazdanpanah, Neda Sepahi, Gholamreza Hatam, Hossein Faramarzi, Hadi Mirzaei, Razie Ranjbar, Ali Ghanbariasad

“…Moreover, multiplex LAMP assay was evaluated and compared based on both standard strains and 55 clinical samples from humans as well as dogs. Various approaches were applied to interpret the multiplex LAMP reaction which deciphered a higher sensitivity when compared to the RT-qPCR for L. infantum (one copy number of plasmid, equal to 0.85 femtograms (fg) of plasmid concentration, and 0.004 parasite DNA per μL) detection while these three standard strains of Leishmania were confirmed to contain 40 DNA copies using RT-qPCR. …”
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Impact of heavy metal pollution on the use of fishing pond land, a former site of used battery smelting by E. Riani, N.A. Butet, M. Ansori, M.R. Cordova

“…Because an area of Cinangka Village has been converted into a fishing pond, it is necessary to investigate whether the fish that live in this pond are accumulating heavy metals, thereby threatening and harming humans as consumers. This research is important for the innovative remediation of land contaminated with used battery smelting waste.METHODS: Analysis of lead, zinc, arsenic, and iron levels in water, sediment, fish, and aquatic plants, as well as histomorphology analysis of several fish organs, was performed. …”
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Pengaruh Kurang Tidur terhadap Berat Badan pada Tikus Wistar Jantan by Deby Nelsya Eka Putri, Ellyza Nasrul, Machdawaty Masri

“…<br />Kata kunci: kurang tidur, berat badan, tikus wistar</p><p>Abstract<br />Sleep deprivation lowers level of leptin and increases level of ghrelin which stimulates appetite and increases the likelihood of obesity in humans. In mice will increases food intake, but decreases the body weight due to high activity in mice. …”
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C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components by Feiyu Jiang, Min Yang, Xili Zhao, Rui Liu, Gangyi Yang, Dongfang Liu, Hua Liu, Hongting Zheng, Zhiming Zhu, Ling Li

“…Circulating CTRP5 is relative to the elevated risk of MetS in humans and may be in part through the effect of insulin resistance. …”
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High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome by Tao Hong, Jiao-Yang Li, Ya-Di Wang, Xiao-Yan Qi, Zhe-Zhen Liao, Poonam Bhadel, Li Ran, Jing Yang, Bin Yan, Jiang-Hua Liu, Xin-Hua Xiao

“…This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in humans. Methods. A total of 131 consecutive patients with MetS, and 162 age-matched, healthy subjects were recruited for this study. …”
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Identification and characterization of Serratia nematophila and Acinetobacter guillouiae from putrid-skin disease lesions in farmed Chinese spiny frog (Quasipaa spinosa) by Ling Guo, Xiyu Jin, Dan Yang, Li Wei, Jie Chen, Zhihua Lin, Li Ma

“…ABSTRACT Serratia and Acinetobacter are recognized as significant opportunistic pathogens affecting aquatic animals and humans. However, their infections in amphibians are poorly documented, and their pathogenicity to the Chinese spiny frog (Quasipaa spinosa) remains unexplored. …”
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