Assessment of Antimicrobial Use for Companion Animals in South Korea: Developing Defined Daily Doses and Investigating Veterinarians’ Perception of AMR by Sun-Min Kim, Heyong-Seok Kim, Jong-Won Kim, Kyung-Duk Min

“…There are global concerns regarding the transmission of antimicrobial-resistant pathogens from animals to humans. Especially, companion animals are increasingly recognized as a potential source due to their close interactions with people, despite a limited number of reported cases. …”
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Adjuntive nicergoline therapy for severe persistent corneal epithelial defects. by Valeria Oliva-Biénzobas, Enrique O. Graue-Hernandez, Guillermo Raul Vera-Duarte, Jesus Cabral-Macías, Juan Serna-Ojeda, Victor Boullosa, Arturo Ramirez-Miranda, Vishal Jhanji, Victor L. Perez, Alejandro Navas

“…Further studies and clinical trials must be conducted to prove safety and efficacy as a treatment for persistent corneal epithelium defects in humans.…”
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Immunogenicity of recombinant fragment of orthopoxvirus p35 protein in mice by Ya. A. Khlusevich, A. L. Matveev, E. P. Goncharova, I. K. Baykov, N. V. Tikunova

“…Despite the elimination of smallpox, orthopoxviruses continue to be a source of biological danger for humans, as cowpox and monkey pox viruses circulate in nature and the last virus can cause both sporadic cases of human diseases and outbreaks of smallpox-like infection. …”
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Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme by Petit, Benoît Eric, Jobelius, Hannah, Bianchino, Gabriella Ines, Guérin, Mélina, Borel, Franck, Chaignon, Philippe, Seemann, Myriam

“…Our previous research revealed that (E)-4-amino-3-methylbut-2-en-1-yl diphosphate (AMBPP) is one of the best inhibitors of IspH, a [4Fe–4S]-dependent enzyme involved in the methylerythritol phosphate pathway that is a valuable target for the discovery of new antibacterial and antiparasitic drugs as it is absent in humans. AMBPP has substantial limitations for drug development due to its poor metabolic stability. …”
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Effect of Simple Oral Dental Extraction on Systemic Serum Amyloid A Concentrations in Horses by Amelia E. Sidwell, Marco Duz, Adeel Khan, Ronald Bodnàr, Sam Luis Hole

“…ABSTRACT Background The translocation of gingival commensals resulting in measurable systemic inflammation has been described in humans and non‐equine veterinary species with dental disorders, particularly periodontal disease. …”
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First Report on the Frequency and Subtype Distribution of <i>Blastocystis</i> sp. in Extensively Reared Holstein-Friesian Cattle from Terceira Island, Azores Archipelago, Portugal by Sara Gomes-Gonçalves, Alexandra Silva, Guilherme Moreira, Nausicaa Gantois, Rubén Garcia Dominguez, Eric Viscogliosi, Magali Chabé, João R. Mesquita

“…However, the low frequency of <i>Blastocystis</i> sp. in this animal cohort possibly attributed to the extensive grazing system practiced on Terceira Island and the limited presence of zoonotic isolates, suggests a minimal risk of transmission from cattle to humans. This study highlights the importance of further research on the transmission dynamics of <i>Blastocystis</i> sp., particularly in regions with varying farming practices, to better understand its epidemiology and zoonotic potential.…”
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An Update on African Trypanocide Pharmaceutics and Resistance. by Keneth Iceland, Kasozi, MacLeod, Ewan Thomas, Ntulume, Ibrahim, Welburn, Susan Christina

“…African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense, and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and T. b rhodesiense are responsible for chronic and acute human African trypanosomiasis (HAT), respectively. …”
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Polymorphism of genes associated with infectious lung diseases in Northern Asian populations and in patients with community-acquired pneumonia by S. V. Mikhailova, L. V. Shcherbakova, N. I. Logvinenko, I. I. Logvinenko, M. I. Voevoda

“…This result may confirm the hypothesis about the selection of this allele in the course of human migration into areas with unfavorable climatic conditions.…”
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RSM-Based Optimization of the Parameters Affecting TiO2-Mediated UV Photocatalysis of Vehicular Emissions in Enclosed Parking Garages by Sandeep Singh, Parteek Thind, Manpreet Kaur Verma, Dapinder Deep Singh, Arjun Sareen, Dheeraj Ahuja, Jasgurpreet Singh Chohan, Raman Kumar, Shubham Sharma, Nima Khalilpoor, Alibek Issakhov

“…Subsequently, exposure of humans to these accumulated pollutants is also expected to degrade their health. …”
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Portable X-ray fluorescence of zinc and selenium with nail clippings-Mother and Infant Nutrition Investigation (MINI). by David E B Fleming, Nelly Madani, Michaela G Kaiser, Jong Sung Kim, Erin Keltie, Natashia Drage, Ying Jin, Jane Coad, Louise Brough

“…Zinc and selenium are essential minerals for human nutrition. Reliable biomarkers of zinc status and selenium status in humans are therefore important. …”
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Fractional-order PID feedback synthesis controller including some external influences on insulin and glucose monitoring by Kottakkaran Sooppy Nisar, Muhammad Farman, Khadija Jamil, Saba Jamil, Evren Hincal

“…The article aims to develop a fractional-order proportional integral derivative (PID) controller to monitor insulin and glucose levels in humans under the influences of stress, excitement, and trauma. …”
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Health risk assessment and microplastic pollution in streams through accumulation and interaction by heavy metals by A.M. Sabilillah, F.R. Palupi, B.K. Adji, A.P. Nugroho

“…BACKGROUND AND OBJECTIVES: The threat posed by microplastics to humans through fish consumption is potentially great due to microplastics’ capacity to adsorb heavy metals. …”
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Silver (Ag) doped graphitic carbon nitride (g-C3N4)/biochar composite photocatalyst for improved photocatalytic degradation of ciprofloxacin (CIP) by Ijlal Idrees, Muhammad Zafar, Malik Adeel Umer, Fahad Rehman, Abdul Razzaq, Seongwan Kim, Yunsook Yang, Woo Young Kim

“…Dumping pharmaceutical wastewater into aquatic bodies vigorously adds to environmental pollution and amplifies antibiotic-resilient bacteria (ARB), a potential danger to humans and living organisms. Among several wastewater treatment methods, the photocatalysis approach under the umbrella of advanced oxidation processes (AOPs) offers a sustainable, inexpensive, and comprehensive treatment of emerging pharmaceutical pollutants (PEPs). …”
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A Genome-Wide Analysis of Long Noncoding RNAs in Circulating Leukocytes and Their Differential Expression in Type 1 Diabetes Patients by Yihan Liu, Xiaoming Du, Jia Cui, Changlong Li, Meng Guo, Jianyi Lv, Xin Liu, Jingtao Dou, Xiaoyan Du, Hongjuan Fang, Zhenwen Chen

“…Further analysis showed that 61.28% of the novel lncRNAs were conserved in humans. A set of 12 lncRNAs were selected for qPCR validation, and 9 of 12 lncRNAs were confirmed to show significant differential expression between the T1D and control validation cohorts. …”
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PWWP domain-containing protein Crf4-3 specifically modulates fungal azole susceptibility by regulating sterol C-14 demethylase ERG11 by Pengju Yu, Shuting Ye, Mi Zhou, Long Zhang, Zhongchi Zhang, Xianyun Sun, Shaojie Li, Chengcheng Hu

“…Considering research on small molecules targeting the PWWP domain in humans, Crf4-3 homolog emerges as a promising target for designing fungal-specific drugs to combat azole resistance.…”
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Normative Values of Brainstem Auditory-Evoked Responses in Sheep by Katharina Suntinger, Adrian Dalbert, Lukas Prochazka, Milena Tegelkamp, Peter Kronen, Karina Klein, Christof Röösli, Alexander Huber, Flurin Pfiffner

“…<b>Conclusions:</b> The normative values for sheep BAERs were reproducible and similar to those of humans. The normative BAER values further support sheep as an adequate animal model for otological research.…”
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Effects of systemic administration of the retinoid Isotretinoin on bone tissue: A narrative literature review by Maria Júlia Bento Martins Parreira, Bruna Trazzi Pagani, Matheus Bento Medeiros Moscatel, Daniela Vieira Buchaim, Carlos Henrique Bertoni Reis, Beatriz Flávia de Moraes Trazzi, Acácio Fuziy, Rogerio Leone Buchaim

“…After analyzing the selected articles, it was possible to observe several reports on hyperostosis or even changes in the formation of bone structures in human patients. Concerning animals, the largest number of studies addressed the changes caused in the formation or development of bone structures by the systemic administration of Isotretinoin. …”
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Level of physical activity of students from the police force academy in Bratislava by Gabriel Bujdos, Štefan Adamčák, Michal Marko, Anna Kozaňáková

“…Being more physically active has never been more important than today as both jobs and leisure activities are becoming increasingly sedentary. Humans have moved from being very physically active to being less and less active each year. …”
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Systematic literature review on Calcium Pyrophosphate Deposition (CPPD) nomenclature: condition elements and clinical states— A Gout, Hyperuricaemia and Crystal-Associated Disease... by Georgios Filippou, Antonella Adinolfi, Emilio Filippucci, Nicola Dalbeth, Robert Terkeltaub, Tristan Pascart, Edoardo Cipolletta, Silvia Sirotti, Charlotte Jauffret, Sara Tedeschi, Daniele Cirillo, Luca Ingrao, Alessandro Lucia

“…This systematic literature review constituted its first step and aimed to provide a state-of-the-art analysis of the medical literature of the last 20 years.Methods A systematic literature search was undertaken in the PubMed, Cochrane and Embase databases between 2000 and 2022, restricted to studies on humans and in the English language. Eight reviewers independently and manually extracted labels related to CPPD concepts, according to an a priori list generated by the authors: pathogenic conditions and pathogenic crystal labels, elementary imaging condition elements and asymptomatic and symptomatic condition states. …”
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Evaluation of the Knowledge, Attitudes and Practice of Veterinary Professionals and Senior Animal Health Students in Central Gondar Zone, Gondar, Ethiopia: Antimicrobial Use and Re... by Abibo Wondie Mekonen, Yesuneh Tefera Mekasha, Melaku Getahun Feleke, Atsede Getaneh, Meron Dereje, Misganew Bafe, Sete Nigussie, Achenef Melaku Beyene

“…ABSTRACT Background Antimicrobial resistance (AMR) poses a worldwide challenge to the well‐being of animals and humans. The emergence of AMR is largely attributed to the improper utilization and overuse of antimicrobials. …”
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