Regulatory Role of GSK-3β on NF-κB, Nitric Oxide, and TNF-α in Group A Streptococcal Infection by Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin

“…Group A streptococcus (GAS) imposes a great burden on humans. Efforts to minimize the associated morbidity and mortality represent a critical issue. …”
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Modulatory Role of Simvastatin against Aluminium Chloride-Induced Behavioural and Biochemical Changes in Rats by Madhavan Nampoothiri, Jessy John, Nitesh Kumar, Jayesh Mudgal, Gopalan Kutty Nampurath, Mallikarjuna Rao Chamallamudi

“…Aluminium, a neurotoxic agent in humans, has been implicated in the pathogenesis of neurodegenerative disorders. …”
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Genetic Analysis of Cytokine Promoters in Nonhuman Primates: Implications for Th1/Th2 Profile Characteristics and SIV Disease Pathogenesis by Pavel Bostik, Melanie Watkins, Francois Villinger, Aftab A. Ansari

“…The shift from a predominant synthesis of prototype Th1 cytokines to Th2 or Th0 type of cytokines by antigen activated PBMC's from HIV infected humans and SIV infected disease susceptible rhesus macaques (RM) has been shown to be associated with disease progression. …”
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Rapid learning with phase-change memory-based in-memory computing through learning-to-learn by Thomas Ortner, Horst Petschenig, Athanasios Vasilopoulos, Roland Renner, Špela Brglez, Thomas Limbacher, Enrique Piñero, Alejandro Linares-Barranco, Angeliki Pantazi, Robert Legenstein

“…However, current AI models struggle in such scenarios, often requiring extensive fine-tuning, computational resources, and data. In contrast, humans can effortlessly adjust to new tasks by transferring knowledge from related ones. …”
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Orlistat ameliorates lipid dysmetabolism in high-fat diet-induced mice via gut microbiota modulation by Chengyan Huang, Yuanhui He, Ping Chai, Zongxin Liu, Sirui Su, Yanhui Zhang, Yuelan Luo, Shuiping Fu

“…It has been shown to improve lipid metabolism and alter intestinal microbial communities in animals and humans. However, the impact of Orlistat-induced changes in gut microbiota on obesity requires further investigation. …”
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Lamotrigine-Valproic Acid Interaction Leading to Stevens–Johnson Syndrome by Marta Vázquez, Cecilia Maldonado, Natalia Guevara, Andrea Rey, Pietro Fagiolino, Antonella Carozzi, Carlos Azambuja

“…As this reactive metabolite is detoxified mainly by enzymatic reactions, involving microsomal epoxide hydrolase and/or GSH-S-transferases and these enzymes are polymorphically expressed in humans, arene oxide toxicity is increased when epoxide hydrolase or GSH-S-transferases is either defective or inhibited or a depletion of intracellular glutathione levels is taking place. …”
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Degradation of PCDD/Fs from incineration of waste at low temperatures for resource utilization of fly ash by Songxuan CHEN, Hao WANG, Dongwei ZHANG, Mengxiao LAN, Zhi SUN, Yuping GAO, Hongbin CAO

“…This includes polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), which are among the most toxic substances to humans and other living organisms. Low-temperature degradation technology has broad prospects in engineering applications due to the advantages of low technical difficulty and operating costs. …”
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Vestiges humains des niveaux de l’Aurignacien ancien du site de Brassempouy (Landes) by Dominique Henry-Gambier, Bruno Maureille, Randall White

“…In sum, the anatomy of the European makers of the Aurignacian is so poorly known that it remains impossible to confirm that the early Aurignacian techno-complex is uniquely the product of anatomically modern populations.Although the intentional modifications of the Brassempouy human remains are presented in detail in a separate publication, we wish to emphasize here that, with primary Aurignacian burials being completely unknown, the modified human teeth from Brassempouy represent one of the rare traces of human intervention with dead bodies that might be interpreted as funerary behavior.…”
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In situ natural radioactivity and radiological hazard assessments of granite gneiss outcrops in parts of the Southwestern Basement Complex of Nigeria by Adedibu Sunny Akingboye, Omowumi Ademila

“…Radioactive emission (gamma ray) emanating from rock materials constitutes threats to humans and their environment. Hence, the natural radioactivity and radiological hazard indices of some granite gneiss outcrops with their residual soils from two different localities within the Southwestern Basement Complex of Nigeria were assessed using Gamma-ray spectrometry. …”
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A review on bioremediation by microbial immobilization-an effective alternative for wastewater treatment by Frank Abimbola Ogundolie, Olorunfemi Oyewole Babalola, Charles Oluwaseun Adetunji, Christiana Eleojo Aruwa, Jacqueline Njikam Manjia, Taoheed Kolawole Muftaudeen

“…Pollution is a threat to aquatic and humans; thus, before the discharge of treated waters back into the environment, wastewater is put through a number of treatment processes to ensure its safety for human use. …”
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Epidemiology of tularemia in the countries of the WHO Eastern Mediterranean Region (EMRO): A systematic review and meta-analysis. by Mohammad Sholeh, Safoura Moradkasani, Saber Esmaeili

“…<h4>Results</h4>A total of 206 studies were identified, of which 20 were finally included in the analysis. The human seroprevalence of tularemia in WHO-EMRO countries was 6.2% (95% CI, 4.2 9.2). …”
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Non-canonical lysosomal lipolysis drives mobilization of adipose tissue energy stores with fasting by GV Naveen Kumar, Rui-Sheng Wang, Ankit X. Sharma, Natalie L. David, Tânia Amorim, Daniel S. Sinden, Nandini K. Doshi, Martin Wabitsch, Sebastien Gingras, Asim Ejaz, J. Peter Rubin, Bradley A. Maron, Pouneh K. Fazeli, Matthew L. Steinhauser

“…Abstract Physiological adaptations to fasting enable humans to survive for prolonged periods without food and involve molecular pathways that may drive life-prolonging effects of dietary restriction in model organisms. …”
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The Insulin Regulatory Network in Adult Hippocampus and Pancreatic Endocrine System by Masanao Machida, Shin Fujimaki, Ryo Hidaka, Makoto Asashima, Tomoko Kuwabara

“…Might it be possible to reactivate stem cells whose functions have deteriorated and that are present in the tissues in which the lesions occur in diabetes, a lifestyle disease, which plagues modern humans and develops as a result of the behavior of insulin-related factor? …”
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Age-related cerebral ventriculomegaly occurs in patients with primary ciliary dyskinesia by Franziska Eisenhuth, Joy E. Agbonze, Adam M. R. Groh, Jesse M. Klostranec, David A. Rudko, Jo Anne Stratton, Adam J. Shapiro

“…We demonstrated highly specific expression levels of known PCD-related genes in human brain multiciliated ependymal cells (p < 0.0001). …”
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Long-term storage of C-141 reference strain of melioidosis agent (<i>Burkholderia pseudomallei</i>) by E. A. Artemeva, L. A. Melnikova, A. P. Rodionov

“…Melioidosis is a highly dangerous infectious disease caused by Hazard Group II bacteria Burkholderia pseudomallei, against which specific prevention and treatment tools have not been developed yet. Both humans and animals suffer from the disease. Previously the disease was prevalent in Southeast Asia regions, but currently is reported almost in all continents of the globe. …”
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Seroepidemiological Survey of Hepatitis E Virus in Intensive Pig Farming in Vojvodina Province, Serbia by Diana Lupulović, Marija Gnjatović, Jasna Prodanov-Radulović, Danica Ćujić, Vladimir Gajdov, Milena Samojlović, Tamaš Petrović

“…Hepatitis E virus (HEV) is the causative agent of acute hepatitis E infection in humans. Two epidemiological patterns of the disease exist—endemic and sporadic. …”
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Fumonisin B1 neurotoxicity: Preclinical evidence, biochemical mechanisms and therapeutic strategies by Blessing A. Obafemi, Isaac A. Adedara, Cássia Pereira Delgado, Olabisi T. Obafemi, Michael Aschner, Joao B.T. Rocha

“…The neurotoxic effects of fungal toxins in both humans and animals have been well documented. Fumonisin B1 (FB1), a mycotoxin produced by fungi of the Fusarium species, is the most toxic fumonisin variant whose neurotoxic effect is still being elucidated. …”
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Muscle Architecture of Leg Muscles: Functional and Clinical Significance by Gurpreet Kaur, Rekha Lalwani, Manal M. Khan, Sunita A Athavale

“…Arching of the foot and eversion are peculiar to humans and recent in evolution. Due to the functional demand of maintaining the medial longitudinal arch and eversion, the tibialis anterior and peroneus longus have more muscle weight and larger physiological cross-sectional area and are potentially more powerful. …”
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Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes by Ying-zhong Lin, Shan-he Lu, Zheng-de Lu, Ying Huang, Ying Shi, Ling Liu, Xiao-yan Wang, Qing-wei Ji

“…CD4+LAP+ Treg cells are a novel subset of Tregs that have been found to ameliorate atherosclerosis in ApoE-/- mice, and these cells also exist in humans. The present study was designed to investigate whether CD4+LAP+ Treg cells are involved in the onset of ACS. …”
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Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport by Wang-Jong Lee, Ernest Mazigo, Jin-Hee Han, Seok Ho Cha

“…Abstract Plasmodium vivax is the most widespread malaria parasite affecting humans, and its eradication is challenging due to the spread of drug-resistant parasites and their ability to remain in liver as a dormant stage. …”
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