Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-Induced PGE2, IL-6, and IL-8 Production by Katriina Vuolteenaho, Anna Koskinen, Meiju Kukkonen, Riina Nieminen, Unto Päivärinta, Teemu Moilanen, Eeva Moilanen

“…In the present paper, the effects of leptin on human OA cartilage were studied. Leptin alone or in combination with IL-1 enhanced the expression of iNOS and COX-2, and production of NO, PGE2, IL-6, and IL-8. …”
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Development of a Robust UPLC Method for Simultaneous Determination of a Novel Combination of Sofosbuvir and Daclatasvir in Human Plasma: Clinical Application to Therapeutic Drug Monitoring by Naser F. Al-Tannak, Ahmed Hemdan, Maya S. Eissa

“…A rapid and selective UPLC-DAD method was developed and validated for simultaneous analysis of the novel two-drug combination Darvoni® for the treatment of HCV: Sofosbuvir (SF)/Daclatasvir (DC) in human plasma using Ledipasvir as internal standard (IS) where the extraction process was conducted using automated SPE. …”
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Expression of CD24 in Human Bone Marrow-Derived Mesenchymal Stromal Cells Is Regulated by TGFβ3 and Induces a Myofibroblast-Like Genotype by Luisa Marilena Schäck, Manuela Buettner, Alexander Wirth, Claudia Neunaber, Christian Krettek, Andrea Hoffmann, Sandra Noack

“…Human bone marrow-derived stromal cells (hBMSCs) derived from the adult organism hold great promise for diverse settings in regenerative medicine. …”
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Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats by Shu Zhu, Dongyu Min, Jianhong Zeng, Yetao Ju, Yao Liu, Xu Chen

“…Stem cells from human exfoliated deciduous teeth (SHED) are a unique postnatal stem cell population with high self-renewal ability that originates from the cranial neural crest. …”
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Blood proteomics and multimodal risk profiling of human volunteers after incision injury: A translational study for advancing personalized pain management after surgery by Daniel Segelcke, Julia R. Sondermann, Christin Kappert, Bruno Pradier, Dennis Görlich, Manfred Fobker, Jan Vollert, Peter K. Zahn, Manuela Schmidt, Esther M. Pogatzki-Zahn

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Human Antibodies Can Cross Guinea Pig Placenta and Bind Its Neonatal Fc Receptor: Implications for Studying Immune Prophylaxis and Therapy during Pregnancy by Evi Budo Struble, Li Ma, Lilin Zhong, A. Lesher, Joel Beren, Pei Zhang

“…We also observe that human IgG binds to an engineered soluble variant of the guinea pig neonatal Fc receptor in vitro in a manner similar to that demonstrated for the human variant, suggesting that this transplacental transport mirrors the receptor-based mechanism seen in humans. …”
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Anti-Inflammatory Activity of Ferula assafoetida Oleo-Gum-Resin (Asafoetida) against TNF-α-Stimulated Human Umbilical Vein Endothelial Cells (HUVECs) by Leila Mobasheri, Mohsen Khorashadizadeh, Hossein Safarpour, Maryam Mohammadi, Gholamreza Anani Sarab, Vahid Reza Askari

“…In this paper, we decided to study the anti-inflammatory effect of ethanolic extract of Ferula assafoetida oleo-gum-resin (asafoetida) against TNF-α-stimulated human umbilical vein endothelial cells (HUVECs). …”
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Ginger polysaccharide UGP1 suppressed human colon cancer growth via p53, Bax/Bcl-2, caspase-3 pathways and immunomodulation by Yanfang Qian, Chenying Shi, Chen Cheng, Dengwei Liao, Junping Liu, Gui-tang Chen

“…Food Science and Human Wellness…”
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Understanding the potential impact of trimester-specific maternal immune activation due to SARS-CoV-2 on early human neurodevelopment and the role of cytokine balance by Alexandre Díaz-Pons, Sergio Castaño-Castaño, Víctor Ortiz-García de la Foz, Ángel Yorca-Ruiz, Carlos Martínez-Asensi, Eva Munarriz-Cuezva, Rosa Ayesa-Arriola

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The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits by T. I. Shashkova, D. D. Gorev, E. D. Pakhomov, A. S. Shadrina, S. Zh. Sharapov, Y. A. Tsepilov, L. C. Karssen, Y. S. Aulchenko

“…Hundreds of genome-wide association studies (GWAS) of human traits are performed each year. The results of GWAS are often published in the form of summary statistics. …”
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High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation by Dariusz Szukiewicz, Michal Pyzlak, Grzegorz Szewczyk, Aleksandra Stangret, Seweryn Trojanowski, Michal Bachanek, Wojciech Braksator, Jaroslaw Wejman

“…Hyperglycemia-induced hyperactivity of chemokine CX3CL1 (fractalkine) occurs in the human placenta. Anti-inflammatory/antioxidant activities of resveratrol (3,5,4′-trihydroxy-trans-stilbene) are related to the modulation of chemokine CX3CL1 and its receptor, CX3CR1, signaling pathways. …”
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A comprehensive characterization biotransformation of chlorinated paraffin by human and carp liver microsomes via liquid chromatography-high-resolution mass spectrometry and screening algorithm by Liujun Chen, Caiming Tang, Zhiqiang Yu, Yanhong Zeng, Bixian Mai, Xiaojun Luo

“…The chlorinated paraffin (CP) monomer 1,2,5,6,9,10-Hexachlorodecane (CP-4) was subjected to in vitro biotransformation using human and carp liver microsomes. Five types of CP-4 metabolites (OH–, keto-, enol-, aldehyde- and carboxy-CP-4) were identified in human liver microsomer while only mono-OH-CP-4 was found in the carp liver microsomes. …”
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The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor by Joseph Franz, Jacob Jerome, Travis Lear, Qiaoke Gong, Nathaniel M. Weathington

“…FBXW12 shRNA increases human epithelial cell growth and cell cycle progression with enhanced constitutive activity of map kinases JNK and ERK. …”
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Formyl Met-Leu-Phe-Stimulated FPR1 Phosphorylation in Plate-Adherent Human Neutrophils: Enhanced Proteolysis but Lack of Inhibition by Platelet-Activating Factor by Algirdas J. Jesaitis, Jeannie Gripentrog, Jovanka M. Voyich

“…N-formyl-Met-Leu-Phe (fMLF) is a model PAMP/DAMP driving human PMN to sites of injury/infection utilizing the GPCR, FPR1. …”
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Human Lice: Body Louse, Pediculus humanus humanus Linnaeus and Head Louse, Pediculus humanus capitis De Geer (Insecta: Phthiraptera (Anoplura): Pediculidae) by H. V. Weems, Jr., Thomas R. Fasulo

“…Reviewed May 2003. EENY-104/IN261: Human Lice: Body Louse, Pediculus humanus humanus Linnaeus and Head Louse, Pediculus humanus capitis De Geer (Insecta: Phthiraptera (=Anoplura): Pediculidae) (ufl.edu) …”
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Detection and Characterization of Shiga Toxin Producing Escherichia coli, Salmonella spp., and Yersinia Strains from Human, Animal, and Food Samples in San Luis, Argentina by Gabriela Isabel Favier, Cecilia Lucero Estrada, Teresa Inés Cortiñas, María Esther Escudero

“…., and Yersinia species was investigated in humans, animals, and foods in San Luis, Argentina. …”
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Perancangan User Experience Aplikasi E-Business Pasar Tradisional Dengan Metode Human Centered Design (Studi Kasus: Pasar Oro-Oro Dowo) by Indrihana Kharismaning Larasati, Widhy Hayuhardhika Nugraha Putra, Retno Indah Rokhmawati

“…Oleh karena itu, melalui penelitian ini diusulkan rancangan aplikasi e-business pasar berdasarkan penerapan elemen UX dengan menggunakan pendekatan Human-Centered Design. Hasil dari penelitian berupa tiga prototype yang diujikan kepada tiga kelompok pengguna yakni pembeli, pedagang, dan admin pasar. …”
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Modeling Human Body Using Four-Pole Debye Model in Piecewise Linear Recursive Convolution FDTD Method for the SAR Calculation in the Case of Vehicular Antenna by Ammar Guellab, Qun Wu

“…We propose an efficient finite difference time domain (FDTD) method based on the piecewise linear recursive convolution (PLRC) technique to evaluate the human body exposure to electromagnetic (EM) radiation. …”
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Knowledge and attitude among Egyptian medical students regarding the role of human papillomavirus vaccine in prevention of oropharyngeal cancer: a questionnaire-based observational study by Mohammed. N. Abdelaziz, Abdullah Hefnawy, Hajer Azzam, Omar Reisha, Omar Hamdy

“…Abstract Squamous cell carcinomas in several anatomical sites are caused by human papillomaviruses (HPV), and oncogenic double-stranded DNA viruses. …”
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Photocatalytic Inactivation Effect of Gold-Doped TiO2 (Au/TiO2) Nanocomposites on Human Colon Carcinoma LoVo Cells by Juan Xu, Yi Sun, Yaomin Zhao, Junjie Huang, Chunmei Chen, Zhiyu Jiang

“…The photocatalytic inactivation effecting of gold-doped TiO2 (Au/TiO2) nanocomposites on human colon carcinoma LoVo cells was investigated for the first time. …”
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