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33581
A double dissociation between semantic and spatial cognition in visual to default network pathways
Published 2025-01-01Get full text
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33582
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33583
Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection
Published 2025-02-01“…In vitro experiments, human aortic smooth muscle cells were extracted, and an in vitro dissection model was constructed with angiotensin II. siRNA silencing studies were performed to investigate the effects of MR-1 and ROCK1 on the development of AD and their interconnections.Results: Analysis of aortic tissues revealed significantly elevated levels of MR-1 and ROCK1 in AD patients, and meanwhile the inflammatory indexes showed the same trend. …”
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33584
Genetic characteristics of influenza A and B viruses circulating in Russia in 2019–2023
Published 2024-12-01“…All influenza A(H1N1)pdm09 viruses in the 2022–2023 season had a previously unknown mutation E224A in HA, which increases its affinity for α-2,3 sialic acids — receptors localized in the human lungs, to which the virus binds via HA. 2 and 3% of influenza A(H1N1)pdm09 viruses in 2019–2020 and 2022–2023, respectively, had the D222N mutation in the receptor-binding site of HA, which is associated with more severe disease. …”
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33585
The Mechanisms of Guaranteeing the Right to Clean Air in Iran and International Documents
Published 2024-10-01“…The municipal law approved in 1955 has also not been able to play a significant role in the realization of the guarantee of the human right to clean air due to the lack of executive guarantees and up-to-dateness. …”
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KATALIKYBĖ IR VISUOMENĖ TARPUKARIO LIETUVOJE
Published 2000-01-01“…Protesting against too active wardship of an individual and a distrust in his (her) ability to make an independent choice and conscious self-determination, which dominated in the practice of the Churc of that times, the modernists defended the necessity to revitalize the authentic faith, deeply hidden in a human, to strengthen his (her) religious aspirations and in such way to cherish a spirituality, because no conscious and morally responsible activities are not able without it. …”
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33588
Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2
Published 2025-01-01“…To apply refined OMVs for human theranostic applications, we developed naturally exposed receptor-binding domain (RBD) OMVs grafted with antigen 43 as a minimal modular system targeting angiotensin-converting enzyme 2 (ACE2).Methods: We constructed E. coli-derived OMVs using the antigen 43 autotransporter system to display RBD referred to as viral mimetic Ag43β 700_RBD OMVs. …”
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Lactate Dehydrogenase-A-Forming LDH5 Promotes Breast Cancer Progression
Published 2025-02-01“…We aimed to explore the roles of LDHA and LDH5 isoenzyme activity in BC, which provides a new insight into LDHA for the treatment of BC.Methods: The expression of LDHA in BC and its relationship with clinicopathological features were obtained from various databases including The Cancer Genome Atlas (TCGA), Human Protein Atlas (HPA), Breast Cancer-Gene Expression Miner (bc-GenExMiner), TNMplot, UALCAN. …”
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33591
Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties
Published 2025-01-01“…So it is concluded that the recently synthesized new dihyropyrimidinone derivatives are highly effective antimicrobial derivatives with non-toxic effects on human cell lines.…”
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33593
East Asian Welfare Regimes 東アジア福祉制度
Published 2010-11-01“…At the same time, a focus on spurring economic development saw social policy subordinated to a larger productivist emphasis on fostering human capital while protecting the prerogatives of capital over labor.The authors draw insights from these lines of analysis, but view the region itself as a place of diversity. …”
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Development of antibacterial magnetic clay-based nanocomposites for water treatment
Published 2024-03-01Get full text
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33600