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32981
Apolipoprotein C-II Mimetic Peptide Promotes the Plasma Clearance of Triglyceride-Rich Lipid Emulsion and the Incorporation of Fatty Acids into Peripheral Tissues of Mice
Published 2019-01-01“…We previously reported that a human apoC-II mimetic peptide (C-II-a) decreased plasma TG in apoC-II mutant mice, as well as in apoE-knockout mice. …”
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32982
A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer
Published 2025-02-01“…Finally, immunofluorescence staining for CD8, CD45, and CXCR4 was performed on human GC tissue samples. Results A total of 1,298 GC patients were included in this comprehensive analysis. …”
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32983
Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae
Published 2024-12-01“…Furthermore, despite lower intracellular bacterial loads, ramR L58P and F165L mutants induce heightened pro‐inflammatory cytokine responses in macrophages and elevate systemic cytokine levels (interleukin [IL]2, IL4, IL6, IL12, interferon‐α, and interferon‐γ) in human blood co‐culture experiments. This study illuminates the critical role of ramR mutations in conferring ERV resistance and enhancing immune responses in K. pneumoniae. …”
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32984
PERSonalised Incentives for Supporting Tobacco cessation (PERSIST) among healthcare employees: a randomised controlled trial protocol
Published 2020-09-01“…Effectiveness will be determined by intention-to-treat analysis.Ethics and dissemination The Erasmus MC Medical Ethics Committee decided that according to the Dutch Human Research Law (WMO), the protocol required no formal ethical approval. …”
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32985
NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis
Published 2025-01-01“…An inverse relationship was observed between NKX6.3 expression and the levels of AurkA and TPX2 in human gastric cancer tissues. Conclusions This study highlights the essential role of NKX6.3 in regulating mitotic integrity and genomic stability in gastric carcinogenesis. …”
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32986
The prevalence and distribution of malaria in Mpumalanga Province before and during COVID-19 (2017 - 2022)
Published 2024-08-01“…Although COVID-19-related restrictions on human movement greatly reduced the malaria burden in Mpumalanga Province, the high-risk group (young mobile men) remained unchanged over the study period. …”
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32987
In Vitro Determination of Antimicrobial, Antioxidant and Antiviral Properties of Greek Plant Extracts
Published 2025-01-01“…These findings provide a foundation for further studies in order to combat infectious diseases and promote human health.…”
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32988
Improved primary stability and load transfer of a customized osseointegrated transfemoral prosthesis compared to a commercial one
Published 2025-01-01“…Materials and methods Six human cadaveric femurs were implanted with commercial stems, while the six contralateral were implanted with customized stems. …”
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32989
Factors associated with early childhood development: results from the Brazilian National Survey on Child Nutrition (ENANI-2019)
Published 2025-02-01“…Introduction The full achievement of early childhood development (ECD) is a human right and adhering to the nurturing care framework may facilitate it.Objective To evaluate the association between distal and proximal variables and developmental quotient (DQ).Methods Data from 14 159 children <5 years were evaluated in the Brazilian National Survey on Child Nutrition. …”
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32990
MLL4 regulates postnatal palate growth and midpalatal suture development
Published 2025-01-01“…Mutations in the MLL4 gene are the major cause of Kabuki syndrome, a human developmental disorder that involves craniofacial birth defects, including anomalies in the palate. …”
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32991
Effects of poultry by-product meal and complete replacement of fish oil with alternative oils on growth performance and gut health of rainbow trout (Oncorhynchus mykiss): a FEEDNET...
Published 2024-10-01“…Values of fatty acid-related health indexes, including atherogenicity index, and thrombogenicity index, confirmed the high nutritional value of trout filet, thus representing a healthy product for human. In addition, the predictions using the FEEDNETICS™ indicated that the tested novel alternative formulations are economically viable. …”
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32992
Time to antiretroviral therapy initiation in HIV-positive patients with opportunistic infections/AIDS-defining illness in Southern Thailand: a prospective cohort study
Published 2024-04-01“…Introduction Rapid antiretroviral therapy (ART) initiation is recommended for all people living with human immunodeficiency virus (HIV). Time to ART initiation in individual patients depends on several factors. …”
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32993
Polybrominated Dibenzo-p-dioxins/Furans (PBDD/Fs) and Diphenyl Ethers (PBDEs) in the Indoor and Outdoor of Gymnasiums
Published 2022-08-01“…Abstract It is still unknown whether the organobromine compounds in the indoor environment of the gyms would affect human health. This study tried to investigate PM2.5 and indoor-dust levels of polybrominated dibenzo-p-dioxins/furans (PBDD/Fs) and diphenyl ethers (PBDEs) in the gyms and then to further assess the health risks of the gym users and employees who were exposed to these organobromines through inhalation and ingestion. …”
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32994
Empirical estimation of saturated soil-paste electrical conductivity in the EU using pedotransfer functions and Quantile Regression Forests: A mapping approach based on LUCAS topso...
Published 2025-02-01“…., primary salinization, but in Mediterranean and Southern Europe, they accumulate because of human interventions on the soil water and solute regimes. …”
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32995
Micronutrient levels of global tropical reef fish communities differ from fisheries capture
Published 2025-01-01“…Fishes in ecosystems are reservoirs of micronutrients with benefits to human health. Yet, the amount of micronutrients contained in fish species on coral reefs and in shallow tropical waters is challenging to estimate, and the micronutrients caught by fisheries remain uncertain. …”
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32996
CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway
Published 2020-01-01“…Peritoneal injection of agonist-CD137 recombinant protein in ApoE−/− mice was used to determine whether CD137 signaling can promote apoptosis in vivo, and human umbilical vein endothelial cells treated with agonist-CD137 recombinant protein, M5580 (a Nrf2 pathway agonist) and CAPE (a NF-κB pathway inhibitor) were used to explore the effect of Nrf2 and NF-κB pathway in CD137 signaling-induced ECs apoptosis in vitro. …”
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32997
A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome
Published 2025-12-01“…The evolutionary conservation analysis of the identified Axin-2 mutant was analyzed among 15 vertebrates from human to zebrafish. The protein structure change was analyzed between the wild-type and mutation-type. …”
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32998
Influence of bottled salad dressings on the development of enamel erosion in the presence or absence of salivary pellicle – An in vitro study
Published 2024-07-01“…Eighty tooth specimens (measuring 4 × 4 × 3 mm) were prepared from extracted human premolars and randomly assigned to four groups (group 1: orange juice; group 2: eggless plain mayonnaise; group 3: sandwich spread; and group 4: thousand island dressing) with 20 samples in each group. …”
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32999
Worldwide patterns and trends in ovarian cancer incidence by histological subtype: a population-based analysis from 1988 to 2017Research in context
Published 2025-01-01“…Findings: The incidence of OC displayed marked disparities across regions and Human Development Index (HDI), with the highest ASRs in Eastern and Central Europe and very high HDI regions, and the lowest in Africa, Asia, and medium HDI regions. …”
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33000
Influence of the Sodium Titanate Crystal Size of Biomimetic Dental Implants on Osteoblastic Behavior: An In Vitro Study
Published 2025-01-01“…The different surfaces were cultured with human osteoblastic cells; cell adhesion was determined at 3 and 14 days, and the degree of mineralization was determined at 14 days via alkaline phosphatase levels. …”
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