Vertical distribution and variability of soil organic carbon and CaCO3 in deep Colluvisols modeled by hyperspectral imaging by Jessica Reyes-Rojas, Julien Guigue, Daniel Žížala, Vít Penížek, Tomáš Hrdlička, Petra Vokurková, Aleš Vaněk, Tereza Zádorová

“…The acceleration of soil erosion in undulating landscapes due to human activities has led to a larger area of land being affected by intensive soil redistribution. …”
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Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE by Mi-Ae Lyu, Ximing Tang, Maria Gabriela Raso, Meixian Huang, Ke Zeng, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar

“…The addition of ruxolitinib increases UCB-Treg cell persistence in peripheral blood in vivo and decreases the soluble form of human inflammatory cytokines including IFN-γ, TNF-α, and sCD40L in plasma along with improvement of skin lesions in SLE xenografts. …”
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Maternal-fetal cytokine profiles in acute SARS-CoV-2 “breakthrough” infection after COVID-19 vaccination by Claire H. Packer, Olyvia Jasset, Nikolina Hanniford, Sara Brigida, Stepan Demidkin, Roy H. Perlis, Roy H. Perlis, Andrea G. Edlow, Andrea G. Edlow, Lydia L. Shook, Lydia L. Shook

“…Cytokines were quantified using the Human Inflammation 20-Plex ProcartaPlex assay.ResultsThere was a significantly higher incidence of severe/critical maternal illness in unvaccinated pregnant individuals with SARS-CoV-2 compared to vaccinated (10/26 (38%) vs. 0/21 (0%), p<0.01). …”
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Predictive factors for axillary pathological complete response to neoadjuvant therapy in elderly breast cancer patients by Yuying Wang, Rui Wang, Di Lu, Yaling Zeng, Xihui Tu, Shiwei Liu, Purong Zhang

“…The univariate analysis results showed that the initial clinical lymph nodes negative(cN0) stage, Human Epidermal Growth Factor Receptor 2(HER2) positivity and breast pathological complete response(bpCR) were significantly correlated with high apCR rates(all P < 0.05). …”
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Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

“…In this study, we aim to investigate the molecular basis of the astrocyte–microglia crosstalk underlying SAE pathogenesis and also to explore the new therapeutic strategies targeting this crosstalk in this devastating disease. We established a human astrocyte/microglia coculture system on a microfluidic device, which allows real-time and high-resolution recording of glial responses to inflammatory stimuli. …”
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Synthesis and Evaluation of Cytotoxic Activity of RuCp(II) Complexes Bearing (Iso)nicotinic Acid Based Ligands by Bárbara Marques, Diogo M. Engrácia, João Franco Machado, Jaime A. S. Coelho, Filipa Mendes, Tânia S. Morais

“…The cytotoxicity of the complexes was evaluated in vitro in several human cancer cell lines, namely melanoma (A375), alveolar adenocarcinoma (A549), epidermoid carcinoma (A431), and breast cancer (MDA-MB 231). …”
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Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes by Shuai Zhang, Ruixue Wang, Kun Luo, Shipeng Gu, Xinyu Liu, Junhan Wang, Ludan Zhang, Lin Sun

“…Aberrant expression of m6A components appears in a variety of human diseases. RNA m6A modification in Drosophila has proven to be involved in sex determination regulated by Sxl and may affect X chromosome expression through the MSL complex. …”
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Mapping Habitat Structures of Endangered Open Grassland Species (<i>E. aurinia</i>) Using a Biotope Classification Based on Very High-Resolution Imagery by Steffen Dietenberger, Marlin M. Mueller, Andreas Henkel, Clémence Dubois, Christian Thiel, Sören Hese

“…Our findings underscore the critical role of human intervention in preserving habitat suitability, particularly in mitigating the adverse effects of natural succession dominated by shrubs and trees. …”
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Characterization and Removal of Condensable Particulate Matter in Flue Gas Studied with Cold Electrode Electrostatic Precipitator by Wenting Liu, Bowen Zhao, Xin Wang, Jianyi Lu

“…This was further evidence of the environmental and human hazards of CPM. The removal of CPM is highly efficient with multi-field synergistic CE-ESP that combines temperature, electric, and concentration fields. …”
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An interval bilateral regulation framework of water resources supply and demand in irrigation area under water sources uncertainty by Zhan Shu, Yan Kang, Ying Gao, Xuemai Shi, Wanxue Li, Shuo Zhang, Songbai Song, Lingjie Li

“…Climate change and human activities have diminished the stability of the water resources system, leading to multiple uncertainties in the prediction of incoming water, reservoir operation optimization on the water supply side, and adaptive adjustments of the water-use structure on the water demand side. …”
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Computer analysis of co-localization of transcription factor binding sites in genome by ChIP-seq data by A. I. Dergilev, A. M. Spitsina, I. V. Chadaeva, A. V. Svichkarev, F. M. Naumenko, E. V. Kulakova, E. R. Galieva, E. E. Vityaev, M. Chen, Y. L. Orlov

“…The computer program of the statistical data processing of gene location and chromatin domains that analyzes experimental data of site localization obtained by ChIP-seq in the mouse genome and the human genome has been developed. The presence of preferences at position of transcription factor binding sites of various types has been revealed, the distances between the nearest groups of TF binding sites Oct4, Nanog, Sox2 and TF binding sites n-Myc and c-Myc have been calculated using this program. …”
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Sources of PM2.5 Oxidative Potential during Haze and Non-haze Seasons in Chiang Mai, Thailand by Pitakchon Ponsawansong, Tippawan Prapamontol, Kittipan Rerkasem, Somporn Chantara, Kraichat Tantrakarnapa, Sawaeng Kawichai, Guoxing Li, Cao Fang, Xiaochuan Pan, Yanlin Zhang

“…These results suggest that during haze episodes, higher levels of PM2.5 and its chemical compositions play a crucial role on OP, particularly DTTv activity, which may induce oxidative stress in human body.…”
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Pharmacological Preconditioning Improves the Viability and Proangiogenic Paracrine Function of Hydrogel-Encapsulated Mesenchymal Stromal Cells by Francesco K. Touani, Melanie Borie, Feryel Azzi, Dominique Trudel, Nicolas Noiseux, Shant Der Sarkissian, Sophie Lerouge

“…Bone marrow MSCs from rat (rMSC) and human (hMSC) origin were preconditioned for 1 hour with celastrol 1 μM or vehicle (DMSO 0.1% v/v), then encapsulated within a chitosan-based thermosensitive hydrogel. …”
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Derivation and Verification of the Relationship between Ablation Index and Baseline Impedance by Zheng Cai, Sainan Li, Qi Zhang, Chenyuan Wang, Zhen Jin, Ming Fu, Shuai Zhang, Ming Liang, Zulu Wang, Yaling Han

“…Under different baseline impedances and corresponding powers, the swine hearts were ablated for 30 s in simulated human circumstances. The baseline impedances, the lesion dimensions, and AIs were recorded. …”
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Comprehensive health risk assessment of urban ambient air pollution (PM2.5, NO2 and O3) in Ghana by Boansi Adu Ababio, Gerheart Winfred Ashong, Thomas Peprah Agyekum, Blessed Adjei Yeboah, Marian Asantewah Nkansah, Jonathan Nartey Hogarh, Michael Kweku Commeh, Edward Ebow Kwaansa-Ansah, Kwabena Dabie, Felix Adulley, Eldad Boansi, Lorenda Sarbeng, Birago Adu Ababio, Maame Serwaa Boapea, Nana Kwabena Oduro Darko, Meshach Kojo Appiah

“…The study assessed urban air quality and evaluated both carcinogenic and non-carcinogenic health risks associated with human exposure to ambient air pollutants. Alarmingly, our findings revealed the yearly median PM2.5 concentrations (50.79–67.97 µg m−3) to be significantly higher than the WHO recommendation of 5 µg m−3. …”
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HER-SAFE study design: an open-label, randomised controlled trial to investigate the safety of withdrawal of pharmacological treatment for recovered HER2-targeted therapy-related c... by Robin Chung, James C Moon, Alexander R Lyon, Charlotte H Manisty, Muhummad Sohaib Nazir, Malcolm Walker, Peter Kellman, Benjamin Dowsing, Daniel Chen, Jessica Artico, Mark Westwood, Hakim-Moulay Dehbi, Rebecca Roylance, Tom Crake, Peter Schmid, Arjun Ghosh, Maria Sol Andres, Joanna Pedra, Orla Worn

“…Introduction A quarter of breast cancers show human epidermal growth factor-2 (HER2) overexpression, where targeted therapy dramatically improves survival. …”
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Pharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> in Canine Cl... by Syed Al Jawad Sayem, Ga-Yeong Lee, Muhammad Aleem Abbas, Seung-Chun Park, Seung-Jin Lee

“…The rising threat of antimicrobial resistance (AMR) is a global concern in both human and veterinary medicine, with multidrug-resistant (MDR) pathogens such as <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> presenting significant challenges. …”
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Attitudes towards persons with disabilities vs. personality traits of Polish students by Iwona Radlińska, Marta Kożybska, Arkadiusz Prajzner, Łukasz Krzywoszański, Beata Karakiewicz

“…ObjectiveThe study aimed to establish the relationship between attitudes towards persons with disabilities and personality traits among Polish students, and whether sociodemographic factors moderate this.MethodsA cross-sectional self-report online survey was conducted on 595 Polish students, aged 18–29, from different fields of study: 1) natural science and engineering technology; 2) social science and humanities; 3) medical and health sciences; 4) law, economics, and management. …”
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Efficacy of Fetal Wharton’s Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles in Metabolic Syndrome by Illayaraja Krishnan, Magdalene Tan Mei Ling, Min Hwei Ng, Jia Xian Law, Mohd Rafizul Mohd Yusof, Thavachelvi Thangarajah, Zalina Mahmood, Nurul Izzati Uda Zahli, Shathiya Rajamanickam, Baskar Subramani, Yogeswaran Lokanathan

“…In addition, sEVs preparations improved inflammation and hemorrhage in the lung and mineralisation in the renal of the treated group. Conclusions: Human fetal WJMSCs-derived sEVs preparations improve all the clusters of MetS in rats except AC and could be further explored as a treatment for MetS.…”
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Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice by Xiaoxiao Zhang, Liang Wang, Asif Iqbal Khan, Ata Ur Rehman, Kavish Hasnain Khinsar, Yi Xin

“…Abstract Chemotherapeutic therapies for cancer are frequently associated with cytotoxic side effects that can be harmful to human health, including the development of intestinal mucositis (IM). …”
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