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31641
Monitoring changes of forest height in California
Published 2025-01-01“…Forests of California are undergoing large-scale disturbances from wildfire and tree mortality, caused by frequent droughts, insect infestations, and human activities. Mapping and monitoring the structure of these forests at high spatial resolution provides the necessary data to better manage forest health, mitigate wildfire risks, and improve carbon sequestration. …”
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31642
CircCCT2/miR-146a-5p/IRAK1 axis promotes the development of head and neck squamous cell carcinoma
Published 2025-01-01“…Circular RNAs (circRNAs) have become key regulators of human malignancies, but further studies are necessary to fully understand their functions and possible causes in HNSCC. …”
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31643
Association between long-term exposure to air pollution and immune-mediated diseases: a population-based cohort study
Published 2022-03-01“…Chronic exposure to levels above the threshold for human protection was associated with a 10% higher risk of developing IMIDs.…”
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31644
Seasonal Variation in Antimicrobial Activity of Crude Extracts of Psammaplysilla sp. 1 from Phillips Reef, South Africa
Published 2021-01-01“…Marine invertebrates constitute a diverse group of marine organisms beneficial to humanity due to their therapeutic significance. The marine sponge species Psammaplysilla sp. 1 was collected from Philips Reef, South Africa, over a four-season period and assayed for antimicrobial potential. …”
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31645
Preferential Expression of B7-H6 in Glioma Stem-Like Cells Enhances Tumor Cell Proliferation via the c-Myc/RNMT Axis
Published 2020-01-01“…B7 homologue 6 (B7-H6), a newly identified member of the B7 costimulatory molecule family, is not only a crucial regulator of NK cell-mediated immune responses through binding to NKp30 but also has clinical implications due to its abnormal expression in human cancers. Here, we show that B7-H6 expression is abnormally upregulated in glioma tissue and that B7-H6 is coexpressed with stem cell marker Sox2. …”
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31646
The optimal neoadjuvant treatment strategy for HR+/HER2 + breast cancer: a network meta-analysis
Published 2025-01-01“…Abstract The efficacy of neoadjuvant therapy varies significantly with hormone receptor (HR) status for patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer (BC). …”
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31647
Efficient evidence selection for systematic reviews in traditional Chinese medicine
Published 2025-01-01“…Methods We integrated an established deep learning model (Evi-BERT combined rule-based method) with Boolean logic algorithms and an expanded retrieval strategy to automatically and accurately select potential evidence with minimal human intervention. The selection process is recorded in real-time, allowing researchers to backtrack and verify its accuracy. …”
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31648
Oil-water emulsion separation on surface-modified capillary ultrafiltration membranes
Published 2024-08-01“…The accumulation of oily wastewater in the environment is becoming an increasing threat to the ecosystem and human health. The modification of ultrafiltration PVDF membrane was investigated in order to create a hydrophilic layer on its surface, to improve performance and increase antifouling properties in the purification of oil-water emulsions.Materials and methods. …”
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31649
Epidemiology of Respiratory Pathogens in Children with Severe Acute Respiratory Infection and Impact of the Multiplex PCR Film Array Respiratory Panel: A 2-Year Study
Published 2021-01-01“…The most common viruses detected were HRV (n = 201) and RSV (n = 124), followed by PIV (n = 35) influenza A (n = 29) and human metapneumovirus (n = 27). Bacteria was found in 8.8% (n = 47), and Bordetella pertussis was the most detected. …”
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31650
Anopheles mosquitoes in Mondulkiri forest, Cambodia: abundance, distribution, seasonal patterns and Plasmodium prevalence
Published 2025-01-01“…Methods Conducted in 9 sites, seven in forested and two in neighbouring villages, over one year, the collection of Anopheles mosquitoes was made hourly for a 72-h period every month, using a human-baited double net trap. Each mosquito was collected using a mouth-aspirator and identified morphologically, and screened for the presence of Plasmodium. …”
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31651
Glucose‐induced LINC01419 reprograms the glycolytic pathway by recruiting YBX1 to enhance PDK1 mRNA stability in hepatocellular carcinoma
Published 2024-12-01“…These findings provide evidence for an unprecedented regulatory mechanism of LINC01419 involving metabolic reprogramming in human cancer. The newly identified LINC01419/YBX1‐PDK1 axis may represent a promising therapeutic target for HCC. …”
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31652
Effectiveness of educational interventions to promote safe handling of pesticides: protocol for a systematic review and meta-analysis
Published 2025-02-01“…Introduction Appropriate use of pesticides minimises harm to human health and the environment. Despite regulations and restrictions on use, however, many farmers still use highly toxic pesticides in ways that endanger their health and the environment. …”
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31653
Anemia and associated factors among HIV/AIDS patients treated with antiretroviral therapy at Mizan-Tepi University Teaching Hospital, Southwest Ethiopia
Published 2024-09-01“…Introduction Human immunodeficiency virus (HIV) and treatments given to HIV patients to reduce complications and fast disease progression, cause a series of hematological abnormalities. …”
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31654
A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer
Published 2024-12-01“…The limited clinical success of previous TRAILR2 agonistic agents, to date, has been ascribed to either poor efficacy or hepatotoxicity. TR2/CDH3 BAB is a human bispecific antibody that relies on binding both CDH3 and TRAILR2 on cell surfaces to achieve TRAILR2 hyperclustering and efficient apoptosis induction by TRAILR2 signaling selectively in CDH3-expressing tumor cells. …”
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31655
Long non-coding RNA NEAT1 promotes ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis
Published 2025-01-01“…Methods We investigated the function of lncRNA NEAT1 in human ovarian granulosa-like tumor cells (KGN). The effects of NEAT1 overexpression or silencing on cell proliferation and cell cycle were evaluated using CCK-8 assays and flow cytometry. …”
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31656
Morphometric and Molecular Characterization of Fasciola spp. in Livestock From Northwestern Provinces of Iran
Published 2024-11-01“…ABSTRACT Background Liver flukes from the genus Fasciola are the causative agents for human and livestock fascioliasis. Accurate identification of Fasciola spp. is essential to understanding the epidemiology of fascioliasis. …”
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31657
Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury
Published 2024-12-01“…This study assessed the role of hypoxia-inducible factor 1α (HIF-1α)-mediated mitophagy in protection against RIRI in vitro and in vivo. The human tubular cell line HK-2 was used to assess hypoxia/reoxygenation (H/R)-induced mitophagy through different in vitro assays, including western blotting, immunofluorescence staining, terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), and reactive oxygen species (ROS) measurement. …”
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31658
Dendritic cell maturation is induced by p53-armed oncolytic adenovirus via tumor-derived exosomes enhancing systemic antitumor immunity
Published 2024-11-01“…Exosomes (Exo53, Exo301, or Exo702) were isolated from conditioned media of human or murine pancreatic cancer cell lines (Panc-1, MiaPaCa-2, and PAN02) after treatment with Ad-p53, OBP-301, or OBP-702. …”
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31659
Ecdysone receptor strongly influences larval–pupal–adult transition and melanization in Tuta absoluta
Published 2024-01-01“…The overuse of traditional pesticides negatively affects both human health and the environment. RNA interference (RNAi), based on double-stranded RNA (dsRNA) induction, can be beneficial in the control of Tuta absoluta; one of the key points of using this technique is the selection of target genes. …”
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31660
Climate change and the sustainable use of medicinal plants: a call for “new” research strategies
Published 2025-02-01“…Climate change and human activities severely impact the viability of plants and ecosystems, threatening the environment, biodiversity, and the sustainable development of plant-based products. …”
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