Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation by Fashuai Wu, Chunxi Ge, Haichun Pan, Yuanyuan Han, Yuji Mishina, Vesa Kaartinen, Renny T. Franceschi

“…In addition, Ddr2 deficiency attenuates HO in mice expressing the ACVR1 mutation associated with human fibrodysplasia ossificans progressiva. In cells migrating into BMP2 implants, DDR2 is co-expressed with GLI1, a skeletal stem cell marker, and DDR2/GLI1-positive cells participate in BMP2-induced bone formation where they contribute to chondrogenic and osteogenic lineages. …”
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Characterizing Antimicrobial Effects of Radiation and Antibiotic Interactions on <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> Using MALDI-TOF MS by Ali Haider, Renáta Homlok, Csilla Mohácsiné Farkas, Tamás Kocsis

“…<b>Background/Objectives:</b> Antibiotic-resistant bacteria are becoming a major challenge in human and veterinary medicine, as well as in food processing. …”
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SLC7A11 is a potential therapeutic target and prognostic biomarker correlated with immune cell infiltration in cervical cancer by Mutangala Muloye Guy, Tingting Bian, Longyun Sun, Yiping Hao, Xinlin Jiao, Wenjing Zhang, Teng Zhang, Baoxia Cui

“…Abstract Background SLC7A11 is importantly in both ferroptosis and disulfidptosis which participated in human development and homeostasis. By utilizing bioinformatics and in vitro validation, we explored SLC7A11's role in cervical cancer. …”
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Vitamin, Trace Element, and Fatty Acid Levels of Vitex agnus-castus L., Juniperus oxycedrus L., and Papaver somniferum L. Plant Seeds by Ahmet Ozkaya, Harun Ciftci, Okkes Yilmaz, Ahmet Zafer Tel, Erol Cil, B. Sitki Cevrimli

“…These parameters in seeds are very important for human life.…”
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Preparedness for and impact of COVID-19 on primary health care delivery in urban and rural Malawi: a mixed methods study by Tracy Morse, Kondwani Chidziwisano, Gift Kawalazira, Mackwellings Maganizo Phiri, Eleanor Elizabeth MacPherson, Mindy Panulo, Khumbo Kalua, Chawanangwa Mahebere Chirambo, Zaziwe Gundah, Penjani Chunda

“…They experienced fatigue and stress due to heavy workloads, stigma in the community and worries about becoming infected with and transmitting COVID-19.Conclusion Resource (human and material) inadequacy shaped the health facility capacity for support and response to COVID-19, and frontline workers may require psychosocial support to manage the impacts of the COVID-19 pandemic.…”
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Constructing Ubudehe? Farmers’ perceptions of drought impacts and resilience capacities in Bugesera, Rwanda by Lazare Nzeyimana, Åsa Danielsson, Veronica Brodén-Gyberg, Lotta Andersson

“…Originality/value – This study analyses farmers’ perceptions of resilience capacities to droughts through a spatiotemporal lens of past droughts, present capital and future challenges by linking scales, knowledge and human–environment nexus. This paper contributes to the knowledge of climate adaptation in Rwanda and to discussions about smallholder farming in the literature on climate change adaptation.…”
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Application of Phi (<italic>&#x03A6;</italic>), the Golden Ratio, in Computing: A Systematic Review by M. Akhtaruzzaman, Jamal Uddin Tanvin, Amir Akramin Shafie, Fahim Shahryer, Sachitra Halder

“…The review also categorizes findings by their specific applications and contexts, providing valuable insights into <inline-formula> <tex-math notation="LaTeX">$\phi $ </tex-math></inline-formula>&#x2019;s impact on mathematics, cryptography, search algorithms, machine learning, artificial intelligence, photonics, natural sciences, system design, power engineering, robotics, and practical human life. This study opens promising avenues for future research on the applications of <inline-formula> <tex-math notation="LaTeX">$\phi $ </tex-math></inline-formula> in diverse fields of science, engineering, and computing.…”
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Measuring anti-transgender stigma in low-income and middle-income countries: a scoping review protocol by Clare Barrington, Jennifer Toller Erausquin, Amanda E Tanner, Tamar Goldenberg, Sulianie Mertus, Mohammed Sheikh Eldin Jibriel

“…A narrative summary of findings will be conducted.Ethics and dissemination As a scoping review (no direct interaction with participants), this study is exempt from human subjects oversight. Understanding context-specific ways to measure anti-trans stigma is urgently needed to support trans health globally. …”
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The multi-omics signatures of telomere length in childhood by Congrong Wang, Dries S. Martens, Mariona Bustamante, Rossella Alfano, Michelle Plusquin, Lea Maitre, John Wright, Rosemary R. C. McEachan, Johanna Lepeule, Remy Slama, Marina Vafeiadi, Leda Chatzi, Regina Grazuleviciene, Kristine B. Gutzkow, Hector Keun, Eva Borràs, Eduard Sabidó, Angel Carracedo, Georgia Escarami, Augusto Anguita-Ruiz, Dolors Pelegrí-Sisó, Juan R. Gonzalez, Martine Vrijheid, Tim S. Nawrot

“…Methods This study included 1001 children aged 6 to 11 years from the Human Early-life Exposome (HELIX) project. Telomere length was quantified via qPCR in peripheral blood of the children. …”
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Automated Cattle Monitoring System for Calving Time Prediction Using Trajectory Data Embedded Time Series Analysis by Wai Hnin Eaindrar Mg, Thi Thi Zin, Pyke Tin, Masaru Aikawa, Kazayuki Honkawa, Yoichiro Horii

“…By utilizing time series analysis on the trajectory data, our system predicts calving events in advance, effectively distinguishing between abnormal (requiring human assistance) and normal (not requiring assistance) for each cow. …”
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Enhanced membrane protein production in HEK293T cells via ATF4 gene knockout: A CRISPR-Cas9 mediated approach by Byung-Jo Choi, Ba Reum Kim, Ho Joong Choi, Ok-Hee Kim, Say-June Kim

“… HEK293T cells are extensively utilized for therapeutic protein production due to their human origin, which enables accurate post-translational modifications. …”
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Aberrant Expression of miR-362 Promotes Lung Cancer Metastasis through Downregulation of Sema3A by Dan Luo, Zheng Zhang, Zhao Zhang, Jia-Yue Li, Jian Cui, Wen-Pu Shi, Xi-Wen Dong, Lin Yuan, Peng Lin, Zhi-Nan Chen, Hui-Jie Bian, Zi-Ling Wang

“…In this study, we found that the level of miR-362 was higher in NSCLC tissues than in adjacent normal tissues and that the level of miR-362 expression was also elevated in five NSCLC cell lines (A549, 95-D, H1299, H292, and H460) relative to a human normal lung epithelial cell line (BEAS2B). …”
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Development of a Multi-Sensor Mobile Device for Urban Air Quality Monitoring at the Street Corner: The SMILE Project by Jonas Pellegrino, Hassen Aziza, Mathieu Guerin, Pascal Taranto, Wenceslas Rahajandraibe, Blaise Ravelo

“…Air pollution is a critical contributor to the global climate change crisis and poses severe threats to human health worldwide. In this context, this paper introduces an innovative multi-sensor air quality monitoring (AQM) device designed to address the critical challenge of atmospheric pollution in urban environments. …”
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The Effects of Three Methods of Luteal Phase Support on Pregnancy Outcomes in Poor Ovarian Responders: A Randomized Clinical Trial by Tahereh Madani, Arezoo Arabipoor, Fariba Ramezanali, Shabnam Khodabakhshi, Zahra Zolfaghary

“…This study aimed to compare the effectiveness of variousluteal phase support (LPS) methods, including progesterone alone, human chorionic gonadotropin (hCG) alone,and the combination of progesterone with hCG, in these patients.Materials and Methods: In this randomized clinical trial, 375 patients diagnosed with POR based on the Bolognacriteria underwent intracytoplasmic sperm injection-embryo transfer (ET) cycles at the Royan Institute betweenNovember 2015 and June 2019. …”
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Automated Web Tool Measurement of Total Hip Arthroplasty Acetabular Component Inclination and Anteversion Angles by Christine Yoon, BS, Anna Eligulashvili, BS, Zeynep Seref-Ferlengez, PhD, Barlas Goker, MD, Eli Kamara, MD, Edward Mardakhaev, MD

“…We introduce a novel automated web tool to streamline the subjective and lengthy process of this manual measurement and compare it to manual human measurements. Methods: One board-certified orthopaedic surgeon used the web tool to make automatic measurements of anteroposterior radiographs of 97 patients who underwent unilateral hip arthroplasty. …”
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Analysis of Air Quality and Health Co-Benefits under Low Carbon Pathway in Taiwan by Hsin-Chih Lai, Shih-Ming Chung, Li-Ling Li, Wen-Yinn Lin, Min-Chuan Hsiao

“…Abstract Climate change has been proven to have adverse effects on human health and ecosystems, especially, the continuous increase in greenhouse gas emissions that are able to drive extreme weather events around the world. …”
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Reducing the solubility of the major birch pollen allergen Bet v 1 by particle-loading mitigates Th2 responses by Amin Kraiem, Erica Pelamatti, Sophie Grosse-Kathoefer, Hilal Demir, Ute Vollmann, Caroline Ehgartner, Maria Stigler, Benjamin Punz, Litty Johnson, Nicola Hüsing, Barbara Bohle, Lorenz Aglas

“…Antigen uptake and presentation was analysed by restimulating human Bet v 1-specific T cell lines. Results: Covalent coupling of Bet v 1 to silica particles resulted in an insoluble antigen with retained IgE-binding and -cross-linking capacity and no increase in adjuvanticity. …”
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Transcriptomic and proteomic analysis of the jejunum revealed the effects and mechanism of protocatechuic acid on alleviating Salmonella typhimurium infection in chickens by Sheng Zhang, Qin Wang, Xiangtian Yao, Jingjing Dong, Guanhuo Li, Yingan Zang, Shouqun Jiang, Yibing Wang

“…Salmonella typhimurium is a common cause of gastroenteritis, which infects animals and human. Protocatechuic acid has anti-inflammatory, immunoregulatory and anti-pathogenic effects, and is expected to be an effective choice for alleviating Salmonella infection and intestinal injury. …”
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Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers by Sergio Sánchez-García, Rafael I. Jaén, Roberto Lozano-Rodríguez, José Avendaño-Ortiz, Alejandro Pascual‐Iglesias, Laura Hurtado-Navarro, Eduardo López-Collazo, Eduardo López-Collazo, Lisardo Boscá, Lisardo Boscá, Patricia Prieto, Patricia Prieto, Patricia Prieto

“…Furthermore, we have studied the correlation between the levels of this SPM and several pathology indicators, finding a significant correlation between increased LXA4 levels and a better prognosis of the patients.ConclusionWe propose to measure systemic LXA4 as a new promising biomarker to predict the survival in patients affected by SARS-CoV-2 and presumably to other viruses that can affect humanity in the future.…”
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MDFGNN-SMMA: prediction of potential small molecule-miRNA associations based on multi-source data fusion and graph neural networks by Jianwei Li, Xukun Zhang, Bing Li, Ziyu Li, Zhenzhen Chen

“…Abstract Background MicroRNAs (miRNAs) are pivotal in the initiation and progression of complex human diseases and have been identified as targets for small molecule (SM) drugs. …”
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