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30961
Immediate-Early Genes and Delayed Primary Response Genes Regulated by NmU in SKBR3 HER-2 Positive Breast Cancer Cell Line
Published 2019-09-01“…EGR1 and NR4A1 act as tumour suppressors in certain human cancers, suggesting that NmU may drive cancer progression by inhibiting important tumour suppressors. …”
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30962
Clinical Factors of Blood Transfusion-Related Acute Lung Injury and Changes in Levels of Treg-Related Cytokines
Published 2022-01-01“…The differences in smoking history, human leukocyte antigen (HLA) antibody II, pretransfusion shock, and CD4 + CD25 + Treg between the TRALI group and non-TRALI group were statistically significant (P<0.05). …”
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30963
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30964
Crimean-Ottoman Factor in the Socio-Cultural System of Russia in Early Modern Times
Published 2020-11-01“…At the same time, it not only did not share the fate of many eastern powers with a traditional way, which turned into the 17th-19th centuries in the colony and semi-colony, but also, on the contrary, it led a successful colonial expansion and demonstrated externally the almost synchronous trends in state building that were inherent in the Western European countries.The author believes that the patrimonial structure of the sociocultural system of the Russian state in the 15-17 centuries contributed to the mobilization of internal material and human resources, coupled with an early superficial “Europeanization” (regular borrowing the military, technical, and cultural experience of modernizing Western Europe), ensured Russia's competitiveness in the world. …”
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30965
La Mélancolie et l’aspect spatio-temporel de l’identité dans Le pion sur l’échiquier d’Irène Némirovsky
Published 2024-12-01“…After the age of doubt enshrouding human subjectivity during the postmodern period, the question of the subject is back on the table. …”
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30966
Development of Binocular Vision
Published 2014-01-01“…Normal binocular vision requires a clear visual axis, sensory fusion, and motoric fusion. In human, the sensitive period of binocular vision development began at around 3 months of age, reaching its peak at the age of 1 to 3 years, had developed completely at the age of 4 years and gradually declined until it stops at the age of 9 years. …”
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30967
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30968
Design of an Integrated Model for Video Summarization Using Multimodal Fusion and YOLO for Crime Scene Analysis
Published 2025-01-01“…Finally, a feedback-driven reinforcement learning framework named RL-HITL allows continuous improvement based on human input, which enhances the adaptability of the system over temporal instance sets. …”
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30969
Targeting protein synthesis pathways in MYC-amplified medulloblastoma
Published 2025-01-01“…Abstract MYC is one of the most deregulated oncogenic transcription factors in human cancers. MYC amplification/or overexpression is most common in Group 3 medulloblastoma and is positively associated with poor prognosis. …”
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30970
circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis
Published 2022-01-01“…IL-6 levels were measured with a human IL-6 ELISA kit based on the provided protocols. …”
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30971
Dental problems and oral microbiome alterations in ulcerative colitis
Published 2025-02-01Get full text
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30972
Predicting nighttime black ice using atmospheric data for efficient winter road maintenance patrols
Published 2025-01-01“…However, patrolling the entire road network on a daily basis requires substantial human and equipment resources. To address this issue, an approach to identify high-risk road sections and prioritize patrolling efforts on these selected sections needs to be established. …”
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30973
بررسی و نقد تعارضات روششناسی علم سنتی در کتاب نیاز به علم مقدس
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30974
Organic UV-filters and freshwater organisms: data gaps impede a robust retrospective environmental risk assessment
Published 2025-01-01“…Although these substances can enter the aquatic environment directly through bathing, authorisation for use in cosmetic products does not require a specific environmental risk assessment, whereas risks to human health are specifically assessed. Furthermore, no environmental quality standards have been proposed at EU level. …”
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30975
Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial
Published 2025-01-01“…Through activation of LANCL2, NIM‐1324 modulates CD4+ T cells to bias signaling and cellular metabolism toward increased immunoregulatory function while providing similar support to phagocytes. In primary human immune cells, NIM‐1324 reduces type I interferon and inflammatory cytokine (IL‐6, IL‐8) production. …”
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30976
Heterogeneity of Intermediate Care Organization Within a Single Healthcare System
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30977
Molecular Characterization and Antibacterial Potential of Endophytic Fungal Isolates from Selected Mangroves along the Coastline of Kenya
Published 2024-01-01“…The increasing emergence and re-emergence of resistant pathogenic microbes causes a health threat to the human population. Scientists have been striving to find novel bioactive compounds and drugs to overcome these obstacles. …”
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30978
Exploring the solutions of tempered (κ,ϖ)-Hilfer hybrid implicit boundary value problem
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30979
Synthesis, Characterization, and Cytotoxicity Research of Sulfur-Containing Metal Complexes
Published 2025-01-01“…In terms of application, the biological activity of complexes (I)–(III) in human cancer cell lines (lung cancer A549, liver cancer SMMC-7721, breast cancer MDA-MB-231, and colon cancer SW480) was tested using the MTS method. …”
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30980
فمنیسم و رمان های سعودی از نظریه تا تطبیق (با نقدی بر رمان «انثی العنکبوت») (عنکبوت ماده)
Published 2022-11-01Get full text
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