RAB3GAP2 dysregulation in adult T-cell leukemia/lymphoma (ATLL) compared to acute lymphoblastic leukemia (ALL): a molecular perspective by Samira Pourrezaei, Arash Letafati, Ghazale Molaverdi, Mehdi Norouzi, Sayed-Hamidreza Mozhgani

“…Abstract Adult T-cell leukemia/lymphoma (ATLL) is a type of blood cancer related to human T-cell lymphotropic virus type 1 (HTLV-1). …”
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Comparative genetic analysis of blood and semen samples in sperm donors from Hunan, China by Chuan Huang, Li-Ming Chu, Bo Liang, Hui-Lan Wu, Bai-Shun Li, Shuai Ren, Mei-Ling Hou, Hong-Chuan Nie, Ling-Yin Kong, Li-Qing Fan, Juan Du, Wen-Bing Zhu

“…This study aimed to determine whether pathogenic variants identified in the sperm of young semen donors are also present in their blood, and whether matching results for blood are consistent with results for sperm.Methods We included 40 paired sperm and blood samples from 40 qualified semen donors at the Hunan Province Human Sperm Bank of China. All samples underwent exome sequencing (ES) analysis, and the pathogenicity was assessed according to the American College of Medical Genetics (ACMG) guidelines. …”
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The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics by Szonja Polett Pósa, Éva Saskői, Lili Bársony, Lőrinc Pongor, Fanni Fekete, János Papp, Anikó Bozsik, Attila Patócs, Henriett Butz

“…Based on data from 1085 human breast cancer specimens, GR pathway expression correlated with migratory, extracellular matrix, and angiogenesis gene signatures. …”
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Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification by Abdul Sattar, Bai Bofeng, M. Adeel Munir, Muhammad Farooq, S. Bilal, M. Imran Khan, Noreen Sher Akbar, Mohammed Ilyas Khan, Mohammad Rehan, Fahid Riaz

“…Water scarcity affects two-thirds of the world’s population and is one of the most important challenges to human development. Nanotechnology led by solar evaporation is emerging to solve water resource problems by absorbing solar energy to vaporize nanofluid samples, especially in areas where seawater resources are abundant and economical. …”
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Assessment of Nitrogen Ceilings for Dutch Agricultural Soils to Avoid Adverse Environmental Impacts by Wim de Vries, Hans Kros, Oene Oenema, Jan Willem Erisman

“…This leads to a series of environmental impacts, including: (1) nitrate (NO3) contamination of drinking water, (2) eutrophication of freshwater lakes, (3) acidification and biodiversity impacts on terrestrial ecosystems, (4) ozone and particle formation affecting human health, and (5) global climate change induced by emissions of N2O. …”
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Study on Change of Landscape Pattern Characteristics of Comprehensive Land Improvement Based on Optimal Spatial Scale by Baoping Feng, Hui Yang, Yarong Ren, Shanshan Zheng, Genxiang Feng, Yuwei Huang

“…This scale can reflect the spatial variability of the landscape pattern in the study area and is the most suitable analysis range. (3) The fragmentation degree of paddy fields as landscape matrix decreased and the landscape dominance degree increased in the comprehensive land improvement; the degree of fragmentation of irrigated land and agricultural land for facilities increased, the aggregation of land for construction increased, the dominance degree of the pond surface decreased, and the overall landscape diversity of each mosaic decreased; the landscape heterogeneity of ditches, rural roads, forest and grassland corridors was weakened, and the ecosystem service function was weakened. (4) The trend of increased fragmentation, simplification of landscape types, and decreased diversity presented by the landscape pattern clearly indicates that the landscape pattern of the study area has been seriously damaged to some extent under the influence of human activities. This damage not only has a direct negative impact on the local ecological environment, but also poses a potential threat to the sustainable development of the region.…”
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Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study by Fattaneh Pahlavan, Shohreh Irani, Mehri Mashayekhi, Samira Vesali, Fatemeh Niknejad, Firoozeh Ahmadi, Narges Bagheri-Lankarani

“…Background: T-shaped uterus is a subclass of dysmorphic uteri according to the European Society of Human Reproductionand Embryology (ESHRE) classification. …”
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Geospatial clustering and correlates of deaths during the Ebola outbreak in Liberia: a Bayesian geoadditive semiparametric analysis of nationally representative cross-sectional sur... by Fiifi Amoako Johnson, Barbara Sakyi

“…The community-level development indicators (global human footprint, gross cell production and population density) had a non-linear associative effect with the observed spatial clustering. …”
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Scalable information extraction from free text electronic health records using large language models by Bowen Gu, Vivian Shao, Ziqian Liao, Valentina Carducci, Santiago Romero Brufau, Jie Yang, Rishi J. Desai

“…Eight advanced open-source LLMs were evaluated against a baseline pattern-matching model. Two human reviewers provided the manual labels, achieving 93% inter-annotator agreement. …”
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Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model by Samy Zaky, Mohamed Elbadry, Maysaa A. Saeed, Hanaa Fathelbab, Fatma Abdelsalam, Mohammed Gamal Abdel-Hamid, Alshaimaa Eid, Asmaa Bakr, Amira Maher, Mona Mohammed Abdelrahman, Mohamed A. Metwally, Mahmoud Saad Berengy, Enaam Ali AlMowafy, Hassan Goabar, Amin Abdel Baki, Ahmed Corie, Osama Hammad, Entesar Elsharkawy, Ahmed Saad, Fatma Ali-Eldin, Ahmed Mahdy, Ramadan Zaky, Reham Hammad, Gamal Essmat

“…They convened to assess the current situation and develop a new consensus on the management of ABM, taking into consideration the human and health potential of Egypt. All the experts who participated in writing and directing this conference belong to different Egyptian universities, and their main clinical interest was infectious diseases. …”
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Screening of Lactic Acid Bacteria Isolated from Fermented Cowpea and Optimization of Biomass Production Conditions by Hong Xu, Danyang Li, Xue Jiang, Qi Pei, Zhengqin Li, Philippe Madjirebaye, Mingyong Xie, Tao Xiong, Zhanggen Liu

“…These results demonstrated that the <i>Pediococcus pentosaceus</i> NCU006063 strain has excellent potential as a fermentation agent and can provide a theoretical base for the in-depth exploration and promotion of fermented cowpea use in human diets.…”
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The Strength of a Story: Partnering With a Community Organization to Destigmatize Substance Use Disorder by Noah Sorkow, Cameron Lauf, Stephen H. Berns

“…Community members expressed how the session helped humanize health care providers and had interest in participating in future sessions. …”
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Team Assembly Mechanisms and the Knowledge Produced in the Mexico’s National Institute of Geriatrics: A Network Analysis and Agent-Based Modeling Approach by Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Augusto Cabrera-Becerril, David Fajardo-Ortiz

“…Mexico’s National Institute of Geriatrics (INGER) is the national research center of reference for matters related to human aging. INGER scientists perform basic, clinical, and demographic research which may imply different scientific cultures working together in the same specialized institution. …”
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Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice by Wanying Cheng, Cenzhu Wang, Meican Ma, Yu Zhou

“…This study aims to understand whether the application of HU could be effective to treat DKD.MethodsThe streptozotocin (STZ)-induced diabetic mice, and high glucose (HG)-treated human renal mesangial cells (HRMCs) were used to investigate the effect of HU on DKD. …”
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Modulation of iron metabolism by new chemicals interacting with the iron regulatory system by Yoshiaki Tsuji, Jun Ninomiya-Tsuji, Maurice Y.F. Shen, Benjamin R. DiFrancesco

“…V004-0872 inhibited the human IRP2 via Cys512 and caused decreased iron levels through reciprocal TfR1 downregulation and ferritin upregulation. …”
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Laminin-5 γ2 Chain Expression Correlates with Unfavorable Prognosis in Colon Carcinomas by C. Lenander, J. K. Habermann, Å. Öst, B. Nilsson, H. Schimmelpenning, K. Tryggvason, G. Auer

“…The results indicate that laminin-5 γ2 chain expression is up-regulated during the progression of human colon cancer and that it plays a role in the aggressiveness of these tumors. …”
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International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review protocol by Katherine Fisher Wilford, Maria Jesus Mena-Iturriaga, Margaret Vugrin, Macarena Wainer, Phillip S Sizer, Gesine Hendrijke Seeber

“…Additionally, results will be presented in tabular and graphical form.Ethics and dissemination As this study will neither involve human subject participation nor utilisation of protected data, ethical approval is not required. …”
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Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures by Isaac Dadzie, Shaibu Adams Avorgbedo, Regina Appiah-Opong, Obed Cudjoe

“…The dried samples were tested on human acute T-cell leukemia (Jurkat) and breast adenocarcinoma (MCF-7) cell lines. …”
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Effect of Presoaking Methods to Break Seed Dormancy in Indigenous Purple Passion Fruits. by Abaho, Darius

“…The indigenous purple passion fruits are grown in Uganda and internationally, for consumption or for juice, which is often added to other fruit juices, to enhance aroma and has nutritional importance, as a source of vitamin A in copious amounts and fair amounts of B 1 and B2 in the human diet. It is also a possible export crop of juice and syrup for flavoring. …”
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INSPIRE Datahub: A Pan-African Integrated Suite of Services For Harmonising Longitudinal Population Health Data Using OHDSI Tools. by Bhattacharjee, Tathagata, Kiwuwa-Muyingo, Sylvia, Kanjala, Chifundo, Maoyi, Molulaqhooa L., Amadi, David, Ochola, Michael, Kadengye, Damazo, Gregory, Arofan, Kiragga, Agnes, Amelia, Taylor, Greenfield, Jay, Slaymaker, Emma, Todd, Jim, INSPIRE Network8

“…The ETL provenance is documented in a machine- and human-readable Implementation Guide (IG), enhancing transparency and usability.…”
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