Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging by Chen Zhu, Youfa Wang, Xiaosong Yang, Qiran Zhao, Wenyan Xu, Xiaolu Wang, Yanjun Liang, Qihui Chen, Shenggen Fan

“…Abstract Background The role of diet in aging is crucial, yet research findings on how specific diets influence human aging remain inconsistent. Understanding the relationship between dietary factors and aging could inform interventions to promote healthier aging outcomes. …”
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Enhancing feature selection for multi-pose facial expression recognition using a hybrid of quantum inspired firefly algorithm and artificial bee colony algorithm by Mu Panliang, Sanjay Madaan, Siddiq Ahmed Babikir Ali, Gowrishankar J., Ali Khatibi, Anas Ratib Alsoud, Vikas Mittal, Lalit Kumar, A. Johnson Santhosh

“…Abstract Facial expression recognition (FER) has advanced applications in various disciplines, including computer vision, Internet of Things, and artificial intelligence, supporting diverse domains such as medical escort services, learning analysis, fatigue detection, and human-computer interaction. The accuracy of these systems is of utmost concern and depends on effective feature selection, which directly impacts their ability to accurately detect facial expressions across various poses. …”
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Interval-Aware Scheduling of Surveillance Drones: Exact and Heuristic Approaches by Kaito Mori, Hiroki Nishikawa, Hiroyuki Tomiyama

“…Drones, with their high mobility and advanced features such as high-resolution cameras, offer a promising alternative to human patrols. Moreover, establishing an optimal patrol schedule for drones is crucial for efficient security operations. …”
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The concept and structural elements of the system of personal empowerment rights of employees by I. M. Kravchenko

“…The article considers the problem of defining the system of personal non-property rights of an employee, as a set of its individual structural basic elements in the system of personal non-property benefits of an individual, and in the general system of human rights. The essence and content of any social, legal phenomena, which are the personal non-property rights of employees, as relevant legal values, can be fully revealed only thanks to the study of objective signs characteristic of these rights. …”
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Identification And Classification of Tattoos In Autopsies; A Retrospective Study by Hatice Kübra Ata Öztürk, Kemalettin Acar, Ayse Kurtuluş Dereli

“…In forensic medicine, tattoos are used for human identification. Tattoos can help determine the origin of death by providing information about individuals' lifestyles. …”
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Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation by Qiongqiong Gao, Zhentao Gao, Minzhi Su, Yong Huang, Chi Zhang, Cuiping Li, Hailun Zhan, Bolong Liu, Xiangfu Zhou

“…In the spinal dorsal horn (SDH), neuroinflammation plays a pivotal role in the development of IC. Injection of human umbilical cord mesenchymal stem cells (hUMSCs) to reduce inflammation is an effective strategy, and heme oxygenase-1 (HO-1) exhibits anti-nociceptive effect in neuroinflammatory pain. …”
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Tumor characteristics and survival rate of axillary metastatic breast cancer patients: a three decades retrospective cohort study by Seyed Mohamad Sadegh Mousavi-kiasary, Mahdis Bayat, Fereshteh Abbasvandi, Batoul Khoundabi, Fatemeh Mousavi, Atieh Akbari, Maryam Bagherian, Afsoon Zandi, Behnam Honarvar, Mohammad Esmaeil Akbari

“…Moreover, estrogen and progesterone receptors, human epidermal growth factor2, tumor pathology type and tumor grade were prognostic factors of axillary LN status. …”
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Cerebrospinal fluid‐specific oligoclonal bands in dogs with idiopathic epilepsy by Junwei Föhr, Julia K. Prümmer, Arianna Maiolini, Eliane Marti, Ilijas Jelcic, Beatriz Vidondo, Mario Ziegler, Andrea Bathen‐Nöthen, Andrea Tipold, Holger A. Volk, Veronika M. Stein

“…Abstract Background In dogs with idiopathic epilepsy (IE), 33% develop resistance to conventional anti‐seizure medication (ASM) despite adequate treatment. In human medicine, an immune‐mediated etiology is suspected in a subset of ASM‐resistant patients with epilepsy and cerebrospinal fluid (CSF)‐specific immunoglobulin G (IgG)‐type oligoclonal bands (OCBs) have been detected. …”
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A bibliometric review of functional ingredients and their efficacy in developing functional biscuits [version 3; peer review: 1 approved, 2 approved with reservations] by Kshama Vishwakarma, Varalakshmi Chandra Sekaran, Vidya Patwardhan, Asha Kamath

“…Introduction Numerous studies have concluded that the functional ingredients benefit human health. Similarly, present times have seen exponential growth in functional food in bakery product segments like breads and biscuits. …”
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Measuring overall functional diversity by aggregating its multiple facets: Functional richness, biomass evenness, trait evenness and dispersion by Laurie Anne Wojcik, Ursula Gaedke, Ellen vanVelzen, Toni Klauschies

“…Abstract Human activities induce environmental changes, which can affect individuals' traits thereby leading to changes in functional diversity and finally in ecosystem functioning. …”
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The association between the amount of fetal fraction in cell-free DNA testing and adverse pregnancy outcomes: A cohort study by Maryam Aryavand, Maryam Nurzadeh, Marjan Ghaemi, Sina Eskandari Delfan, Vajiheh Marsoosi

“…No significant association was found between FF and multiple of the median of pregnancy-associated plasma protein-A and free β-human chorionic gonadotropin. Conclusion: The amount of FF may be considered a predictor of certain adverse pregnancy outcomes. …”
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The Role of Correcting Structural and Functional Albumin Properties in Ascites Control in Decompensated Cirrhotic Patients by A. A. Turkina, M. V. Maevskaya, M. S. Zharkova, V. T. Ivashkin

“…The first group received standard treatment for cirrhosis, the second — standard treatment and replacement therapy with 20 % human albumin solution at a dose of 200 mL per week for 3 months.Results. …”
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Design of an Improved Method for Visual Rendering in the Metaverse Using CIEM and MSRANet by Janapati Venkata Krishna, Priyanka Singh, Regonda Nagaraju, Setti Vidya Sagar Appaji, Attuluri Uday Kiran, K. Spandana

“…Finally, BEER, standing for Bioinspired Energy-Efficient Rendering, borrows from the energy-efficient way of visual processing in the human brain through a spiking neural network that reduces energy consumption by 35% without image quality degradation. …”
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Modulation of the thiol redox proteome by sugarcane ash-derived silica nanoparticles: insights into chronic kidney disease of unknown etiology by Arthur D. Stem, Cole R. Michel, Peter S. Harris, Keegan L. Rogers, Matthew Gibb, Carlos A. Roncal-Jimenez, Richard Reisdorph, Richard J. Johnson, James R. Roede, Kristofer S. Fritz, Jared M. Brown

“…Methods In order to characterize the impact of sugarcane ash derived (SAD) SiNPs on human kidney proximal convoluted tubule (PCT) cells and identify potential mechanisms of toxicity, HK-2 cells were exposed to treatments of either pristine, manufactured, 200 nm SiNPs or SAD SiNPs and changes to cellular energy metabolism and redox state were determined. …”
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The association of sexual frequency with cardiovascular diseases incidence and all-cause mortality by Tian-Qi Teng, Jing Liu, Meng-Meng Wang, De-Gang Mo, Rui Chen, Jia-Chao Xu, Zi-Han Dong, Ning Zhang, Hai-Chu Yu

“…Abstract Sexual activity exists in a complex relationship with human health. This study aims to elucidate the correlation between the sexual frequency and the incidence of cardiovascular diseases (CVD) and all-cause mortality among young and middle-aged adults of the United States. …”
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Stem cell-derived exosome treatment for acute spinal cord injury: a systematic review and meta-analysis based on preclinical evidence by Chunlin Mou, Ziyao Xia, Ziyao Xia, Ziyao Xia, Xiujuan Wang, Xunan Dai, Jiaxian Wang, Chun Zhang, Chun Zhang, Yongsheng Xu, Yongsheng Xu, Yongsheng Xu

“…Exosomes were derived from bone marrow, adipose tissue, umbilical cord or human placental MSCs. Meta-analysis results showed no statistically significant differences in therapeutic efficacy among these MSC-exos sources at various treatment time points.ConclusionMSC-exos demonstrated considerable promise in improving motor function in SCI-affected rats, with bone marrow MSC-derived exosomes having particularly notable effectiveness.…”
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Commonality of Virulence-Promoting Function in Rhodococcus equi Virulence Associated Proteins (Vaps) by Timothy R. Ganderton, Daniel Ghete, Karen Hogg, Graeme J. Park, Christoph G. Baumann, Anthony J. Wilkinson, Paul R. Pryor

“…These data suggest that VapA production, which is often found in equine infections, can be substituted by VapK and B (produced by plasmids often found in porcine species) or VapN (produced by plasmids often isolated in bovine and human samples). These data imply that the molecular mechanism(s) that VapA uses to neutralise lysosomal acidity should also be seen in VapN and K which will help guide researchers in identifying their precise mode of action and aid the future development of targeted therapeutics.…”
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A real-world Pharmacovigilance study of brodalumab based on the FDA adverse event reporting system by Ke He, Kaidi Zhao, Tingyi Yin, Meng Liu, Jiashu Liu, Wenqian Du, Xinyi Liu, Baochen Cheng, Dewu Zhang, Yan Zheng

“…Abstract Brodalumab, a humanized monoclonal antibody that targets the interleukin-17 receptor A, is primarily used to manage moderate-to-severe plaque psoriasis. …”
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A Multi-Target Threat Assessment Method Based on Objective Three-Way Decision by Humberto Baldessarini Pires, Lamartine Nogueira Frutuoso Guimaraes, Sergio Reboucas

“…Traditional 3WD often utilizes a subjectively defined, fixed risk avoidance coefficient that reflects human perception of battlefield information. This study addresses these challenges by proposing a dynamic multi-target TA method within an intuitionistic fuzzy environment, eliminating subjective parameter settings in the technique for order of preference by similarity to ideal solution (TOPSIS), and incorporating an objective 3WD (O3WD) approach. …”
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Hokuriku-plus familial hypercholesterolaemia registry study: rationale and study design by Hiroshi Matsumoto, Akihiro Nomura, Hayato Tada, Hirofumi Okada, Atsushi Nohara, Masa-aki Kawashiri, Koji Maeno, Manabu Fujimoto, Shohei Yoshida, Masaya Shimojima, Toyonobu Tsuda, Mika Mori, Shin-ichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Noboru Fujino, Akihiro Inazu, Shizuko Takahara, Yasuhito Imai, Takao Matsubara, Kenji Miwa, Masanobu Namura, Hidenobu Terai, Taiji Yoshida, Tsutomu Araki, Masahiro Minamoto, Toru Aburao, Yuji Ito, Chiaki Nakanishi, Suguru Kawasaki, Yasuhiro Todo, Junji Koizumi, Yoshihito Kita, Hiroaki Shintaku, Akihiko Hodatsu, Hidekazu Ino, Toshinori Higashikata, Mutsuko Takata, Katsushi Misawa, Masato Yamaguchi, Yoshihiro Noji, Kazuo Osato, Tomohito Mabuchi, Taro Ichise, Bunji Kaku, Shoji Katsuda, Katsuharu Uchiyama, Kensuke Fujioka, Takuya Nakahashi, Tsuyoshi Nozue, Ichiro Michishita, Kazuo Usuda, Kanichi Otowa, Kazuyasu Okeie, Satoshi Hirota, Isao Aburadani, Keisuke Kurokawa, Osamu Takatori, Shunichiro Hondo, Hiroyuki Oda, Shigeo Takata, Hisayoshi Murai, Masaki Kinoshita, Hideo Nagai, Yoshiteru Sekiguchi, Satoru Sakagami, Wataru Omi, Chikara Fujita, Tatsuo Katsuki, Hiroshi Ootsuji, Atsushi Igarashi, Manabu Nakano, Seiichiro Okura, Yasuhito Mitamura, Naoki Sugimoto, Masakazu Yamamoto, Hironobu Akao, Kouji Kajinami, Masayuki Takamura

“…The secondary endpoints are as follows: LDL cholesterol, secondary ASCVD events and the occurrence of other diseases including hypertension, diabetes and malignancies.Ethics and dissemination This study is being conducted in compliance with the Declaration of Helsinki, the Ethical Guidelines for Medical and Health Research Involving Human Subjects, and all other applicable laws and guidelines in Japan. …”
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