Spray-Induced Gene Silencing (SIGS): Nanocarrier-Mediated dsRNA Delivery Improves RNAi Efficiency in the Management of Lettuce Gray Mold Caused by <i>Botrytis cinerea</i> by Maria Spada, Claudio Pugliesi, Marco Fambrini, Diego Palpacelli, Andrea Caneo, Susanna Pecchia

“…The management of gray mold disease is still mainly based on the use of chemicals, which could have harmful effects not only due to impacts on the environment and human health, but also because they favor the development of fungicide-resistant strains. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…The visually-based immunochromatographic test (ICT) described herein allows for quick detection and quantification of IgG and IgM FH-FHAA complexes in human EDTA-plasma or serum. This ICT offers improved detection of FHAAs compared to ELISA as demonstrated by cases where the ICT identifies FH-FHAA complexes in samples that tested negative with the free FHAA ELISA. …”
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Fatal intoxication after oral ingestion of amphetamine: Two case reports by Evelyn Pawlik, Felix Mayer, Oliver Temme

“…The toxicity of the amphetamine by-products on the human body remains unclear and is subject of further studies.…”
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HPV vaccination and Native Americans: protocol for a systematic review of factors associated with HPV vaccine uptake among American Indians and Alaska Natives in the USA by Sameer Vali Gopalani, Ami E Sedani, Amanda E Janitz, Shari C Clifton, Julie Stoner, Jennifer Peck, Ashley Comiford, Alicia L Salvatore, Janis Campbell

“…Introduction The nine-valent human papillomavirus (HPV) vaccine could prevent an estimated 92% of the cancers attributable to HPV types targeted by the vaccine. …”
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The Role of Antioxidant Activity of Chitosan-Pinus merkusii Extract Nanoparticle in against Lead Acetate-Induced Toxicity in Rat Pancreas by G. Wardani, Ernawati, K. Eraiko, S. A. Sudjarwo

“…Lead is one of the heavy metals with oxidative stress that causes toxicity in human and animals. The aim of this study was to evaluate the antioxidant activity of Chitosan-Pinus merkusii extract nanoparticle on lead acetate-induced toxicity in rat pancreas. …”
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Comprehensive analysis of H3K27me3 LOCKs under different DNA methylation contexts reveal epigenetic redistribution in tumorigenesis by Yuan Liang, Mengni Liu, Bingyuan Liu, Benjamin Ziman, Guanjie Peng, Qiong Mao, Xingzhe Wang, Lizhen Jiang, De-Chen Lin, Yueyuan Zheng

“…Result In this study, we identify and categorize H3K27me3 LOCKs in 109 normal human samples, distinguishing between long and short LOCKs. …”
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Distribution and Conservation of Ephedra rhytidosperma by Chao Tan, David Kay Ferguson, Yong Yang

“…ABSTRACT With global warming and increasingly intensified human activities, numerous species are on the verge of extinction, ca. 28% of living species are threatened globally, although conservation of endangered species has received worldwide attention. …”
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Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies. by Peter R McIlroy, Le Thanh Mai Pham, Thomas Sheffield, Maxwell A Stefan, Christine E Thatcher, James Jaryenneh, Jennifer L Schwedler, Anupama Sinha, Christopher A Sumner, Iris K A Jones, Stephen Won, Ryan C Bruneau, Dina R Weilhammer, Zhuoming Liu, Sean Whelan, Oscar A Negrete, Kenneth L Sale, Brooke Harmon

“…Previously, we designed a next-generation synthetic humanized nanobody (Nb) phage display library and demonstrated that this library could be used to rapidly identify highly specific and potent neutralizing heavy chain-only antibodies (HCAbs) with prophylactic and therapeutic efficacy in vivo against the original SARS-CoV-2. …”
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Impact of COVID-19 on Utilization of Healthcare Services Among People Living with HIV (PLHIV): A Systematic Review by Enyinnaya Ukaegbu, Maulenkul Tilektes, Antonio Sarria-Santamera

“…., “COVID-19 pandemic”, “SARS-CoV-2”, “Health services utilization”, “People living with Human immunodeficiency virus”, was included. <i>Results:</i> There was an overall decline in the utilization of health services such as medical consultations, ART uptake, and viral load monitoring by PLHIV at primary health centers at the forefront of care delivery. …”
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Move to improve - Prescribing physical activity and deprescribing paracetamol for low back pain: Protocol for a hybrid type III feasibility study by David Roberts, Paulo H Ferreira, Josielli Comachio, Paula R Beckenkamp, Thomas Patterson, Mark Halliday, Emma Kwan-Yee Ho

“…Qualitative (open-ended questions) will be integrated with the feasibility trial outcomes to inform the design of a full-scale randomised controlled trial.Ethics and dissemination This study has ethical approval from the Sydney Local Health District Human Research Ethics Committee (2023/ETH02683). …”
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Host-symbiont-gene phylogenetic reconciliation by Menet, Hugo, Trung, Alexia Nguyen, Daubin, Vincent, Tannier, Eric

“…We finally evaluate different hypotheses on human population histories in the light of their coevolving Helicobacter pylori symbionts, reconciled together with their genes. …”
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Evaluation of relationships between dogs and owners: the turkish translation, reliability and validity study of cat/dog owner relationship scale (c/dors) by Ufuk Kaya, Dogukan Ozen, Murat Onur Yazlik, Selim Kosem, İsmayil Safa Gurcan

“…In addition, this study will encourage the examination of pet-human relationships in Turkey through with scale development and adaptation studies.…”
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Effect of electrical stimulation with a cochlear implant on tinnitus impact: protocol of an individual patient data meta-analysis by Inge Stegeman, Adriana L Smit, Kelly Assouly

“…Second, linear regression analyses will be used to model the effect of electrical stimulation on tinnitus impact based on relevant predictors.Ethics and dissemination The Medical Research Involving Human Subject Act does not apply, and ethical approval is not required. …”
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Evolution characteristics and causes of iodine and fluoride in groundwater of Hengshui city in North China by Yapeng Tuo, Baizhong Yan, Junbai Gai, Yanbo Yu, Xinkai Zhan, Yuanjing Zhang, Shuwei Qiu

“…Abstract Iodine and fluoride are essential trace elements for human health, with both deficiency and excess intake impacting well-being. …”
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Efficacy and safety of high-intensity focused ultrasound combined with suction curettage for the treatment of caesarean scar pregnancy: a systematic review and single-arm meta-anal... by Yu Jiang, Yang Liu, Nian Liu, Shize Qin, Shuting Zhong, Xiaohua Huang

“…Furthermore, post-treatment follow-up showed that serum β-human chorionic gonadotropin levels were rapidly normalized (average of 25.48 days) and menstruation returned (average of 33.03 days). …”
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Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…This review provides a comprehensive analysis of the mechanisms and functions of autophagy, exploring its association with various human diseases. It presents a novel perspective on the potential clinical applications of autophagy, highlighting its role in the development of therapeutic strategies and deepening our understanding of this essential cellular process.…”
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TiO2 Nanocoatings with Controllable Crystal Type and Nanoscale Topography on Zirconia Implants to Accelerate Bone Formation by Nan Li, Zhichao Liu, Guanqi Liu, Zhi Wang, Xianwei Guo, Chuanbin Guo, Jianmin Han

“…In addition, in vitro cytocompatibility and osteogenic potential performance of the coatings were evaluated by human bone marrow mesenchymal stem cells (hBMSCs), and in vivo osseointegration performance was assessed in a rat femoral condyle model. …”
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Thyroid response to blocking sympathetic activity in chronic cold-exposed hunters in East Greenland: a case–control study by Mette Motzfeldt Jensen, Charlotte Elberling Almasi, Hans Christian Florian-Sørensen, Stine Linding Andersen, Stig Andersen

“…Background: Thyroid hormones and sympathetic stimulation are needed for activating brown adipose tissue (BAT) during cold exposure. Studies of human cold exposure have demonstrated both increased production and raised clearance of triiodothyronine (T3). …”
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ULK1 methylation promotes TGF‐β1‐induced endometrial fibrosis via the FOXP1/DNMT1 axis by Yuhua Zeng, Qing Feng

“…Downregulation of FOXP1 could inhibit human endometrial stromal cells proliferation and autophagy, as well as decrease the expression of fibrogenic factors (collagen type I alpha 1 chain [COL1A1], fibronectin [FN], and alpha‐smooth muscle actin [α‐SMA]). …”
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Sodium dichloroisocyanurate: a promising candidate for the disinfection of resilient drain biofilm by Abbie Martin, Natasha Doyle, Tom F. O'Mahony

“…Biofilms can cause a range of human diseases and are responsible for 1.7 million hospital-acquired infections in the US annually, providing an economic burden of $11.5 billion in treatment costs. …”
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