Honduran nursing care to pressure injuries in patients with invasive mechanical ventilation: A qualitative study by Yoselin Isabel Vallejo Bustamante, Oscar Fidel Antunez Martinez

“…Allocating resources toward nursing care and their professional growth is an investment in providing humane treatment and ensuring the prevention and management of pressure injuries in critical care patients. …”
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Advances in Hemodynamic Analysis in Cardiovascular Diseases Investigation of Energetic Characteristics of Adult and Pediatric Sputnik Left Ventricular Assist Devices during Mock Ci... by Alexander A. Pugovkin, Aleksandr G. Markov, Sergey V. Selishchev, Leonie Korn, Marian Walter, Steffen Leonhardt, Leo A. Bockeria, Olga L. Bockeria, Dmitry V. Telyshev

“…The need to simulate the operating conditions of the human body is a key factor in every study and engineering process of a bioengineering device developed for implantation. …”
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MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial by Mrinal Gounder, Melissa Johnson, Rebecca S. Heist, Geoffrey I. Shapiro, Sophie Postel-Vinay, Frederick H. Wilson, Elena Garralda, Gerburg Wulf, Caroline Almon, Salah Nabhan, Elia Aguado-Fraile, Peng He, Mathilde Romagnoli, Mohammad Hossain, Rohini Narayanaswamy, Amel Sadou-Dubourgnoux, Michael Cooper, Vasileios Askoxylakis, Howard A. Burris, Josep Tabernero

“…We report results from the first-in-human, phase 1 trial of AG-270/S095033 as monotherapy in patients with advanced malignancies (ClinicalTrials.gov Identifier: NCT03435250). …”
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ESD-YOLOv8: An Efficient Solar Cell Fault Detection Model Based on YOLOv8 by Lingyun Zhang, Xu Wu, Zihan Liu, Panlin Yu, Mingfen Yang

“…This study not only alleviates the burden of human detection but also provides an efficient and high-precision solution for intelligent PV system fault diagnosis.…”
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Construction and Characterization of Adenovirus Vectors Encoding Aspartate-β-Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma by Yujiao Zhou, Feifei Liu, Chengmin Li, Guo Shi, Xiaolei Xu, Xue Luo, Yuanling Zhang, Jingjie Fu, Aizhong Zeng, Limin Chen

“…Firstly, the total AAH mRNA was extracted from human HCC tissues; the cDNA was amplified by RT-PCR, verified, and sequenced after TA cloning. …”
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Investigation of the effects of Afyonkarahisar Region hot springs water on blood calcium and some hormon levels in experimentally-created osteoporosis in rats by Bülent Elitok, Tolgahan Saygin, Yavuz Ulusoy, Bahadir Kilinç

“…Today, one of the most common non-communicable diseases, which, according the World Health Organization experts, dominates the structure of human morbidity and mortality is osteoporosis. The aim of this study was to determine the effect of water from the hot springs of the Afyonkarahisar region on the calcium content and the levels of certain hormones in the blood of rats with experimentally induced osteoporosis. 25 female albino rats of the same age were used in the experiment. …”
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Gastrointestinal protozoa in pet cats from Anhui province: prevalence and molecular characterization by Hao Zhang, Xing Tong, Zhonghui Ma, Tao Zhang, Feng Wu, Qiong Wu, Congshan Yang, Chunyang Han

“…IntroductionTo investigate the prevalence of Tritrichomonas foetus, Pentatrichomonas hominis, Giardia intestinalis, Cryptosporidium, Microsporidium, and Sarcocystis in domestic cats in Anhui Province, China, and their potential role as zoonotic hosts for human infection, a total of 304 fecal samples from two different sources were screened for the presence of related pathogens.MethodsUsing microscopy, along with polymerase chain reaction (PCR) or nested PCR amplification, followed by genotyping through sequence analysis.ResultsThe infection rates of T. foetus, P. hominis, G. intestinalis, Cryptosporidium, Enterocytozoon bieneusi, and Sarcocystis were 5.6%, 0%, 1.7%, 0.7%, 2.6%, and 0%, respectively. …”
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Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages by Yanxia Fu, Jun Li, Mengdi Li, Junfeng Xu, Zheng Rong, Fangli Ren, Yinyin Wang, Jianqiu Sheng, Zhijie Chang

“…This study is aimed at performing a safety evaluation and evaluating the role of human umbilical cord mesenchymal stem cells (HUC-MSCs) on tumorigenesis. …”
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Extracting Regular Building Footprints Using Projection Histogram Method from UAV-Based 3D Models by Yaoyao Ren, Xing Li, Fangyuqing Jin, Chunmei Li, Wei Liu, Erzhu Li, Lianpeng Zhang

“…Current techniques heavily rely on human expertise and involve repetitive, labor-intensive manual operations. …”
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Assessing Short-term Flood Impact on Land Use Dynamics in Iran’s Central Zagros: A Case Study of Sefid Kuh Protected Area by Soheyl Moradi, Hossein Moradi, Jafar Dolatshah, Azita Rezvani

“… Floods are extreme events that can alter the land cover and land use patterns in mountainous regions, with significant consequences for biodiversity, ecosystem services, and human well-being. However, there is a lack of comprehensive and integrated studies on the short-term and long-term effects of floods on land cover dynamics in the Central Zagros region, which is a climate change hotspot and a protected area with rich flora and fauna. …”
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Antioxidant Peptide Derived from Spirulina maxima Suppresses HIF1α-Induced Invasive Migration of HT1080 Fibrosarcoma Cells by Won Suk Kim, Won Kyo Jung, Sun Joo Park

“…Here, we show that an antioxidant peptide derived from Spirulina maxima suppresses hypoxia-induced invasive migration of HT1080 human fibrosarcoma cells. HT1080 cells treated with a hypoxia-inducing agent, CoCl2, exhibited an increase in invasive migration and intracellular reactive oxygen species (ROS), which is associated with an increase in the expression of hypoxia-induced factor 1α (HIF1α) accompanied by the activation of PI3K/Akt and ERK1/2. …”
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Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…The anti-inflammatory and anti-obesity activities of C-Akm extract were studied by testing the extract (50 μg/mL) on the polarization of THP-1 into macrophages, the secretion of pro-inflammatory cytokines in LPS-stimulated PBMCs, and the secretion of leptin and adiponectin in adipospheroids derived from human adipose stem cells. Finally, the extract was examined in 3D co-culture model mimicking inflamed obese adipose tissue. …”
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Intensity of Oestrus Signalling Is the Most Relevant Indicator for Animal Well-Being in High-Producing Dairy Cows by Emanuel Garcia, Jan Hultgren, Pontus Fällman, Johanna Geust, Bo Algers, George Stilwell, Stefan Gunnarsson, Heriberto Rodriguez-Martinez

“…Avoidance distances were short (<1 m), reflecting good human-animal interaction. Visually-recorded standing oestrus yielded 4.8 fold higher odds of pregnancy, respectively 4.6-fold higher odds of calving. …”
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Factors involved in the development of hospital-acquired conditions in older patients in acute care settings: a scoping review by Mélanie Verdon, Thomas Agoritsas, Cécile Jaques, Sophie Pouzols, Cédric Mabire

“…Personal factors, medications, and the human and work environment were the most frequent subcategories of factors retrieved, whereas social factors, hydration and nutrition, and organizational factors were less common. …”
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Peri Cholecystectomy Bile Analysis for Fasciola hepatica Eggs in Sulaimani Teaching Hospital by Seerwan Hama Shareef, Taher Abdullah Hawramy, Osman jamal nasrulla, Karwn Hama amin, Dara Ahmed Mohammed, Raz Seerwan Hama

“…It is a widespread disease throughout the world; nearly (2.4 – 17) millions of people is infected. Human is an accidental final host by ingestion of contaminated plants and water by metacircaria. …”
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The blue revolution: sustainable water management for a thirsty world by Amarachi Paschaline Onyena, Kabari Sam

“…Abstract The twenty-first century presents critical challenges to global water resources, with rising consumption, scarcity, and security issues threatening human well-being and ecosystem health. Regions such as the Middle East, North Africa, China, and the USA are already experiencing significant impacts on health, livelihoods, and ecosystems due to the global water crisis. …”
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Scaling up of parenting support to prevent violence against children in Tanzania: insights from policymakers and service providers by Sabine van Tuyll van Serooskereken Rakotomalala, Kija Nyalali, Joyce Wamoyi, Onduru Gervas Onduru, Gerry Mshana, F. Marijn Stok, Mara A. Yerkes, John B. F. De Wit

“…Current factors hindering the scale-up include the lack of a common understanding of what evidence-based parenting programmes entail, inadequate provision of human and financial capital to implement the programmes using community resources and deeply engrained social norms around adultism and gender. …”
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Study on SHP2 Conformational Transition and Structural Characterization of Its High-Potency Allosteric Inhibitors by Molecular Dynamics Simulations Combined with Machine Learning by Baerlike Wujieti, Mingtian Hao, Erxia Liu, Luqi Zhou, Huanchao Wang, Yu Zhang, Wei Cui, Bozhen Chen

“…The src-homology 2 domain-containing phosphatase 2 (SHP2) is a human cytoplasmic protein tyrosine phosphatase that plays a crucial role in cellular signal transduction. …”
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Isolation and characterization of a novel lytic phage K14-2 infecting diverse species of the genus Klebsiella and Raoultella by Seomin Kang, Jeong-Eun Han, Young-Sik Choi, In-Chul Jeong, Jin-Woo Bae, Jin-Woo Bae, Jin-Woo Bae

“…Notably, the genera Klebsiella and Raoultella are of concern due to their association with human infections and the transfer of antibiotic-resistance genes. …”
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MHD effect on peristaltic motion of Williamson fluid via porous channel with suction and injection by K. Chakradhar, K. Nandagopal, Vishnudasu Prashanthi, A. Parandhama, T. Somaiah, B.V. Sai Thrinath, Nainaru Tarakaramu, Ghulam Rasool, Dilsora Abduvalieva

“…These materials play a critical role in diagnosing underlying issues within human organs that rely on peristaltic pumping for fluid transfer, such as the stomach, intestines, and ureters. …”
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