Incidence of Cervical Cancer in Young Adult Women: Level of Knowledge for its Prevention by Edison Sotalin Nivela, José Sixto Calvopiña del Castillo, Carlos Alberto Llerena Gómez

“…No significant correlation was observed between knowledge and place of residence, economic situation, family history of cervical cancer, center where the cytological examination was performed, use of contraceptives, smoking or vaccination against human papillomavirus. It was found that knowledge was related to age, education, occupation, marital status, frequency of gynecological examinations, frequency of cytology, awareness of one's knowledge and the number of births. …”
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Comparative analysis of EGFR mutations in circulating tumor DNA and primary tumor tissues from lung cancer patients using BEAMing PCR by Duhita Mirikar, Nandini Banerjee, Kumar Prabhash, Rajiv Kumar Kaushal, Vanita Naronha, C. S. Pramesh, George Karimundackal, Amit Joshi, Swapnil Rane, Ranjan Basak

“…Abstract In this study, we measured human epidermal growth factor receptor (EGFR) mutations in both tissue and circulating tumor DNA (ctDNA) by using beads, emulsions, amplifications and magnetic polymerase chain reaction (BEAMing PCR). …”
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Historical Perspective of Inborn Errors of Immunity in Turkey by Yıldız Camcıoğlu

“…Screening tests for IEIs and intravenous or subcutaneous immunoglobulin replacement treatment are now being offered to all patients. Human stem cell therapy treatments are accessible for patients with T-cell deficiency, and available monoclonal therapies are provided to IEIs patients in Turkey.…”
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Conditioned Medium from Adipose-Derived Stem Cell Inhibits Jurkat Cell Proliferation through TGF-β1 and p38/MAPK Pathway by Xiuxia Wang, Yinmin Wang, Xianyu Zhou, Fei Liu

“…ADSCs were isolated from Human Adipose Tissues, and Enzyme-linked Immunosorbent Assay (ELISA) was used to identify the concentration of transforming growth factor β1 (TGF-β1) in ADSC-CM. …”
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HMGB1 released from pyroptotic vascular endothelial cells promotes immune disorders in exertional heatstroke by Chaoping Yu, Yang Huang, Jiangang Xie, Chujun Duan, Shanshou Liu, Wei Zhao, Yutong Wang, Ran Zhuang, Junjie Li, Wen Yin

“…HMGB1 localization and release were visualized using immunofluorescence staining. Human umbilical vein endothelial cells (HUVECs) and THP-1 cells were co-cultured to study the effects of HMGB1 on macrophages. …”
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Current state and promise of user-centered design to harness explainable AI in clinical decision-support systems for patients with CNS tumors by Eric W. Prince, Eric W. Prince, Eric W. Prince, David M. Mirsky, David M. Mirsky, Todd C. Hankinson, Todd C. Hankinson, Carsten Görg, Carsten Görg

“…We also discuss how explainable AI tools, embedded in a human-centered decision-making process and different from fully automated solutions, can potentially enhance clinician performance. …”
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Inhibitory Effect on the Tyrosinase Activity and Low Cytotoxicity of Monounsaturated Long-Chain Chelating Fatty Ester by ANTONIO SERGIO C. CARVALHO, TATIANA N. PEDROSA, HERONILDES A. DANTAS FILHO, RAQUEL C. MONTENEGRO, EMERSON S. LIMA, MARNE C. DE VASCONCELLOS, ALBERDAN S. SANTOS

“…Finally, the assay with the series showed no hemolytic activity (EC50> 250 μg mL-1), and not cytotoxic to B16F10, ACP-02, and human dermal fibroblast cells at 100 µM and showed no hemolytic potential at the concentration of IC50 250 µM.…”
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ROCK Inhibitor-Induced Promotion of Retinal Pigment Epithelial Cell Motility during Wound Healing by Hiroyuki Kamao, Atsushi Miki, Junichi Kiryu

“…The aim of this study is to evaluate the effect of Rho-associated coiled-coil containing kinase (ROCK) inhibitor Y27632 on retinal pigment epithelial (RPE) cell motility during wound healing. Methods. Human RPE cells were cultured in media with and without 10 μM Y27632. …”
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Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms by Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu

“…Secondly, exploring microbiota biomarkers related to aging and discussing future possibility using dietary regime/components targeted to aging-related microbiota biomarkers promote human healthy lifespan. Thirdly, dietary intervention can effectively improve the imbalance of gut microbiota related to aging, such as probiotics, prebiotics, and postbiotics, but their effects vary among.…”
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Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

“…Translating this approach to the human setting is achievable and will yield both critical insights into the fundamental basis of alloreactivity and powerful tools for immune monitoring in transplantation.…”
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Seroprevalence to herpesviruses in patients with primary brain gliomas by T. A. Zykova, O. I. Kit, E. E. Rostorguev, E. A. Shevyakova, N. S. Kuznetsova

“…Antibodies of classes M and G to herpes simplex virus types 1, 2 (HSV-1,2), cytomegalovirus (CMV), Epstein-Barr virus (EBV), human herpes virus type 6 (HHV-6) were determined by ELISA using JSC "Vector-Best" reagent kits.Results. …”
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Morphological and Molecular Characterization of Toxigenic Aspergillus flavus from Groundnut Kernels in Kenya by Robert O. Okayo, Darius O. Andika, Mathews M. Dida, George O. K’Otuto, Bernard M. Gichimu

“…Pathogenesis of Aspergillus flavus on important agricultural products is a key concern on human health due to the synthesis and secretion of the hazardous secondary metabolite, aflatoxin. …”
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Genomic analysis and antibiotic resistance of a multidrug-resistant bacterium isolated from pharmaceutical wastewater treatment plant sludge by Ningyu Sun, Hu Gao, Xinbo Zhang, Zeyou Chen, Anping Peng

“…Additionally, the N4 genome contained 187 genes associated with human disease and 249 virulence factors, underscoring its potential pathogenicity. …”
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Investigating the needs and barriers for prevention, control, and treatment of HIV/AIDS in transgender population: a systematic review of literature by Heshmatollah Sofimajidpour, Ghobad Moradi, Hojat Dehghanbanadaki, Marzieh Mahboobi, Mobin Azami, Parisa Khodakhah, Mohammad Aziz Rasouli, Yousef Moradi

“…Introduction The purpose of this systematic review was to identify the health needs related to prevention, control, and treatment of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) in transgender people from the perspective of transgender individuals and health policy-makers. …”
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Biodegradation of CAHs and BTEX in groundwater at a multi-polluted pesticide site undergoing natural attenuation: Insights from identifying key bioindicators using machine learning... by Feiyang Xia, Tingting Fan, Mengjie Wang, Lu Yang, Da Ding, Jing Wei, Yan Zhou, Dengdeng Jiang, Shaopo Deng

“…These contaminants pose serious risks to ecosystems and human health. Natural attenuation (NA) has emerged as a sustainable solution, with microorganisms playing a crucial role in pollutant biodegradation. …”
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sRrsR-Net: A New Low-Light Image Enhancement Network via Raw Image Reconstruction by Zhiyong Hong, Dexin Zhen, Liping Xiong, Xuechen Li, Yuhan Lin

“…Most existing low-light image enhancement (LIE) methods are primarily designed for human-vision-friendly image formats, such as sRGB, due to their convenient storage and smaller file sizes. …”
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Monitoring the Induction of Heat Shock Factor 1/Heat Shock Protein 70 Expression following 17-Allylamino-Demethoxygeldanamycin Treatment by Positron Emission Tomography and Optical... by Mikhail Doubrovin, Jian T. Che, Inna Serganova, Ekaterina Moroz, David B. Solit, Lyudmila Ageyeva, Tatiana Kochetkova, Nagavarakishore Pillarsetti, Ronald Finn, Neal Rosen, Ronald G. Blasberg

“…MicroPET imaging based on [ 124 I]iodide accumulation in pQHNIG70-transduced RG2 xenografts showed a significant 6.2-fold reporter response to 17-AAG, with a corresponding increase in tumor HSP70 and in tumor human sodium iodide symporter and green fluorescent protein reporter proteins. …”
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Electronic database of regulatory observations as a tool of public administration in the context of digitalization in construction by I. V. Karakozova, I. M. Lisitsyn, K. V. Boldyshev

“…There is a necessity to carry out several measurements at different sites to obtain averaged data, including due to the influence of the human factor in establishing fix points and forming a map of work operations, which creates the possibility of data falsification. …”
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Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease. by Sydney R Coffey, Robert M Bragg, Shawn Minnig, Seth A Ament, Jeffrey P Cantle, Anne Glickenhaus, Daniel Shelnut, José M Carrillo, Dominic D Shuttleworth, Julie-Anne Rodier, Kimihiro Noguchi, C Frank Bennett, Nathan D Price, Holly B Kordasiewicz, Jeffrey B Carroll

“…To study the relationship between peripheral huntingtin levels and striatal HD phenotypes, we utilized a knock-in model of the human HD mutation (the B6.HttQ111/+ mouse). We treated mice with ASOs from 2-10 months of age, a time period over which significant HD-relevant signs progressively develop in the brains of HttQ111/+ mice. …”
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Preparing for old age in a geragogic approach. The conceptual assumptions for gerontological education of people aged 50+ “Towards a dignified and successful old age” by Anna Maria Leszczyńska-Rejchert

“…Results Old age as a phase of human life is regarded in geragogy as a task of an individual. …”
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