Physical education curriculum systematizing based on action research: a collaborative network between teacher-researchers from public schools in Quixadá — Ceará, Brazil by Rener Victor Oliveira de Souza, Maurício Teodoro de Souza, Luciano Nascimento Corsino, Willian Lazaretti da Conceição, Carla Ulasowicz, Luciana Venâncio, Luciana Venâncio, Luiz Sanches Neto, Luiz Sanches Neto

“…For more than forty years, physical education has been associated with human sciences in Brazil, with an emphasis on the dynamics of culture. …”
Get full text

Improved Left Ventricular Aneurysm Repair with Cell- and Cytokine-Seeded Collagen Patches by Hui Qu, Bao-dong Xie, Jian Wu, Bo Lv, Jun-bo Chuai, Jian-zhong Li, Jun Cai, Hua Wu, Shu-lin Jiang, Xiao-ping Leng, Kai Kang

“…In vitro, the biomaterial exhibited an enhanced mechanical strength maintaining a porous ultrastructure, and the constant release of cytokines promoted the proliferation of seeded human mesenchymal stem cells (hMSCs). In vivo, with the hMSC-seeded, cytokine-immobilized patch (MSCs + GF patch), we performed modified SVR for rats with left ventricular aneurysm postmyocardial infarction (MI). …”
Get full text

Remote Minimally Invasive Surgery – Haptic Feedback and Selective Automation in Medical Robotics by Christoph Staub, Keita Ono, Hermann Mayer, Alois Knoll, Heinz Ulbrich, Robert Bauernschmitt

“…We present a novel approach that extends human-machine skill-transfer by a scaffolding framework. …”
Get full text

Risk factors for silicotuberculosis among miners: a scoping review by Mansour F. Saliba, Zeina Z. Karam, Moussa El Khayat, Elizabeth Koka, Dana A. Halwani, Joly Ghanawi, Layal Hneiny, Mey Jurdi, Hassan R. Dhaini, Umayya Musharrafieh, Rima R. Habib

“…Findings identified various STB risk factors including demographic factors such as age and sex, lifestyle factors including smoking and alcohol intake, clinical factors such as history of TB, grades of silicosis, and human immunodeficiency virus (HIV), in addition to occupational factors encompassing silica exposure, duration of employment, and type of work setting. …”
Get full text

Immunogenicity of HIV-1 <i>Env</i> mRNA and <i>Env-Gag</i> VLP mRNA Vaccines in Mice by Qi Ma, Jing Yang, Xiaoguang Zhang, Hongxia Li, Yanzhe Hao, Xia Feng

“…Background: The development of a protective vaccine is critical for conclusively ending the human immunodeficiency virus (HIV) epidemic. Methods: We constructed nucleotide-modified mRNA vaccines expressing HIV-1 Env and Gag proteins. …”
Get full text

miR-203 Expression in Exfoliated Cells of Tongue Coating Represents a Sensitive and Specific Biomarker of Gastroesophageal Reflux Disease by Xiuli Yan, Shengliang Zhu, Hui Zhang

“…MicroRNAs (miRNAs) have been implicated in the pathophysiology of numerous human diseases including gastroesophageal reflux disease (GERD). …”
Get full text

Object-Level Contrastive-Learning-Based Multi-Branch Network for Building Change Detection from Bi-Temporal Remote Sensing Images by Shiming Li, Fengtao Yan, Cheng Liao, Qingfeng Hu, Kaifeng Ma, Wei Wang, Hui Zhang

“…Buildings are fundamental elements of human environments, and detecting changes in them is crucial for land cover studies, urban expansion monitoring, and the detection of illegal construction activities. …”
Get full text

Navigating technostress: a deep dive into health practitioners' technological challenges in hospital settings by Hamid Keshavarz, Hamid Reza Saeidnia, Ting Wang

“…By shedding light on the key stressors and their distribution, these findings can inform human resources management strategies within healthcare systems to effectively support practitioners in navigating and managing technostress challenges.…”
Get full text

Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivating NF‐κB and MAPK signaling pathways by Xiaoqing Zhu, Cheng Tian, Dan Yao, Siqi Li, Junjiang Lv, Yongwen Chen, Xiaoyong Huang

“…Medicinal plants contain bioactive compounds that have therapeutic effects on human health. Ophioglossum vulgatum L. is a representative species of the fern genus Ophioglossum that has anti‐inflammatory properties as recognized in folk medicine. …”
Get full text

Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity by Boyuan Peng, Ziwei Li, Yong Cheng, Henghua Jiang, Qingsong Ye, Guangli Han

“…Methods We isolated and identified dental pulp stem cell-derived intracellular vesicles (DPSC-IV) from human dental pulp tissue. To investigate its effect, DPSC-IV was added to osteoblast or osteoclast differentiation medium. …”
Get full text

Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway by Song Yang, Lei Yao, Xiaolong Wang, Hao Sun, Chaogang Du, Chengpeng Song, Jingyu Fu, Yongjun Wu, Hongwu Huang, Chuansi Wang, Yongsen Wang, Yixiang Xie

“…The CCK-8 assay, migration assay, tube formation assay, qPCR, and Western blotting were performed in human umbilical vein endothelial cells (HUVECs). …”
Get full text

Hollow Salt Prepared Through Spray Drying with Alginate Enhances Salinity Perception to Reduce Sodium Intake by Qian Jiang, Jiayi Yan, Chen Song, Yunning Yang, Guangyuan Chen, Fanhua Kong, Jingfeng Yang, Shuang Song

“…Currently, high-salt diets have become one of the world’s biggest dietary crisis and long-term high-salt diets are seriously detrimental to human health. In response to this situation, the present study proposed a saltiness enhancement strategy using alginate, which is a dietary fibre from brown algae and has many health benefits, such as regulating intestinal microbiota, anti-hypertension and anti-obesity. …”
Get full text

Eucalyptus-based livelihoods: enhancing household food security and resilience in Northwest Ethiopia by Fasika Belay, Fasika Belay, Messay Mulugeta, Teferee Makonnen

“…However, households that own eucalyptus plantations demonstrate a lower index for human capital than those without eucalyptus plantations. …”
Get full text

Reconstruction of climatic events from the 16th century in Transylvania: interdisciplinary analysis based on historical sources by Ovidiu Răzvan Gaceu, Tudor Caciora, Ștefan Baias, Cezar Morar, Mihai Dudaș, Marius Stupariu, Maria Maxim

“…Finally, the manuscript emphasizes the significant role of the climate in shaping the historical and socio-economic landscape of Transylvania in the 16th century, offering perspectives on the complex interactions between the climate and the human component.…”
Get full text

Innovation in entrepreneurship during the time of COVID-19: a scoping review of the scientific evidence from Peru [version 1; peer review: 1 approved, 2 approved with reservations] by Sofía Almendra Alvarado-Suyo, Giovanni Di Deus Ocupa-Meneses, Johanna de Jesús Stephanie Gago-Chávez, Hitler Giovanni Ocupa-Cabrera, Josefina Amanda Suyo-Vega, Rosario Violeta Grijalva-Salazar, Víctor Hugo Fernández-Bedoya, Monica Elisa Meneses-La-Riva

“…Background: Entrepreneurship involves the actions of designing, launching and managing a business that initially starts small and grows along with the human structure that integrates it.  The health crisis caused by coronavirus disease 2019 (COVID-19) had negative effects on health, but also on business; many ventures had to innovate in order to survive in this uncertain environment. …”
Get full text

Grazing-Induced Habitat Degradation: Challenges to Giant Panda Survival Resulting from Declining Bamboo and Soil Quality by Huawei Tian, Ying Zeng, Zejun Zhang, Ming Lu, Wei Wei

“…Grazing is the primary human-induced disturbance affecting giant panda (<i>Ailuropoda melanoleuca</i>) habitats and has a severe impact on the long-term sustainability of the giant panda population. …”
Get full text

Stress-Driven Production of γ-Aminobutyric Acid Using Non-Conventional Yeast Strains <i>Kluyveromyces marxianus</i> JMY140K and <i>Metschnikowia reukaufii</i> JMY075 by Ting-Ting Fan, Chao Chen, Du-Wen Zeng, Feng-Lou Wang, Zhao-Xian Xu, Ming-Jie Jin, Yue Zou, Jun Li, Xin-Qing Zhao

“…The culture filtrate of <i>K. marxianus</i> JMY140K also showed promising activities in human skin cells. In addition, <i>K. marxianus</i> JMY140K could also produce GABA using rice straw hydrolysate, which indicated that it has the potential to produce GABA using renewable biomass. …”
Get full text

Multidrug efflux pumps of Pseudomonas aeruginosa show selectivity for their natural substrates by Léna Mazza, Léna Mazza, Alexandre Bory, Alexandre Bory, Alexandre Luscher, Alexandre Luscher, Joachim Kloehn, Jean-Luc Wolfender, Jean-Luc Wolfender, Christian van Delden, Christian van Delden, Thilo Köhler, Thilo Köhler

“…Antibiotic-resistant Gram-negative bacteria are an increasing threat to human health. Strategies to restore antibiotic efficacy include targeting multidrug efflux pumps by competitive efflux pump inhibitors. …”
Get full text

Programme de développement professionnel des fonctionnaires en vue de la création d’un environnement éducatif sûr dans le cadre de la loi martiale by Iryna Trubavina, Oleksandr Cherednychenko, Kirill Nedria, Nadiia Oliinyk

“…The research methodology of the article is a complex of scientific approaches that determined the content, methods and form of training: competencebased, axiological, systemic, risk-oriented approaches, public administration approach; approach for human rights. Research methods included analysis of theoretical sources, synthesis, modeling, oral interviews of educators, generalization of experience, and observation. …”
Get full text

An Overview of Innovative Techniques to Improve Cervical Cancer Screening by Esther R. Nijhuis, Nathalie Reesink-Peters, G. Bea A. Wisman, Hans W. Nijman, Jelmer van Zanden, Haukeline Volders, Harry Hollema, Albert J. H. Suurmeijer, Ed Schuuring, Ate G. J. van der Zee

“…When available, data on cost– effectiveness of certain approaches will be provided. In short, Human Papillomavirus (HPV) DNA detection stands closest to implementation in nation-wide screening programs of all markers reviewed. …”
Get full text