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27861
The role of ESRP1 in solid tumor development through the regulation of CD44 splicing and EMT processes
Published 2025-02-01“…Despite significant progress in the field of cancer treatment in recent years, cancer remains one of the main factors shortening human life expectancy. The field of cancer research is increasingly focusing on the role of tumor-related oncogenes and heterogeneous proteins in the development of cancer. …”
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27862
Current State of Normative and Legal Regulation of the Rehabilitation Institution in Criminal Proceedings of Ukraine
Published 2020-12-01“…The authir has carried out theoretical study of the current state of regulation of the rehabilitation institution in criminal proceedings of Ukraine, the immediate task of which is to protect human and civil rights and freedoms within relations between the state and an individual. …”
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27863
Comprehensive analysis of cuproptosis-related genes in immune infiltration and development of a novel diagnostic model for acute kidney injury
Published 2024-12-01“…Our study aimed to investigate the involvement of cuproptosis-related genes (CRGs) in AKI.Methods Identification of CRGs was conducted using differential expression analysis, and subsequent Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted using human sequencing profiles. Utilizing CIBERSORT algorithm, receiver operating characteristic (ROC) curve analysis, nomogram development, and decision curve analysis (DCA), the association among immune scores, CRGs, and the diagnostic value of these genes was explored.Results Notably, six CRGs (FDX1, DLD, DLAT, DBT, PDHA1, and ATP7A) were identified as significant differentiators between AKI and non-AKI groups. …”
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27864
Social media activism and women's health: Endometriosis awareness and support
Published 2025-01-01“…Methods We used a mixed-method approach of combining computational analyses (topic modeling and word association) and human coding (qualitative thematic analysis) of Instagram posts on endometriosis. …”
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27865
Fabrication of Core-Shell PEI/pBMP2-PLGA Electrospun Scaffold for Gene Delivery to Periodontal Ligament Stem Cells
Published 2016-01-01“…In this study, the bioactive PEI (polyethylenimine)/pBMP2- (bone morphogenetic protein-2 plasmid-) PLGA (poly(D, L-lactic-co-glycolic acid)) core-shell scaffolds were prepared using coaxial electrospinning for a controlled gene delivery to hPDLSCs (human periodontal ligament stem cells). The pBMP2 was encapsulated in the PEI phase as a core and PLGA was employed to control pBMP2 release as a shell. …”
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27866
Investigation of a transformer-based hybrid artificial neural networks for climate data prediction and analysis
Published 2025-01-01“…IntroductionClimate change isone of the major challenges facing the world today, causing frequent extreme weather events that significantly impact human production, life, and the ecological environment. …”
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27867
Optimization and Characterization of Silver Nanoparticle by Endophytic Fungi Penicillium sp. Isolated from Curcuma longa (Turmeric) and Application Studies against MDR E. coli and...
Published 2014-01-01“…Development of ecofriendly and reliable processes for the synthesis of nanoparticles has attracted considerable interest in nanotechnology because of its tremendous impetus in modulating metals into nanosize to their potential use for human benefits. In this study an endophytic fungus, Penicillium sp., isolated from healthy leaves of Curcuma longa (turmeric) was subjected to extracellular biosynthesis of silver nanoparticles (AgNps) and their activity against MDR E. coli and S. aureus. …”
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27868
Science Under Political Change: The Experience of Russian Genetics in the 1960s
Published 2015-10-01“…The paper underlines that Leningrad and Novosibirsk Universities made a great contribution to the revival of human resources in the Soviet genetics. At the same time many other biological departments and institutes were going through the reorganization of the Soviet biology with lots of difficulties. …”
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27869
Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities
Published 2025-02-01“…In this study, we characterized L. fermentum SD7, which was isolated from the human oral cavity. The genome of L. fermentum SD7 was approximately 2.27 Mb in size, with a 51.1 % GC content. …”
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27870
3D-Printing of Artificial Aortic Heart Valve Using UV-Cured Silicone: Design and Performance Analysis
Published 2025-01-01“…The advancement of medical 3D printing technology includes several enhancements, such as decreasing the length of surgical procedures and minimizing anesthesia exposure, improving preoperative planning, creating personalized replicas of tissues and bones specific to individual patients, bioprinting, and providing alternatives to human organ transplants. The range of materials accessible for 3D printing within the healthcare industry is significantly narrower when compared with conventional manufacturing techniques. …”
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27871
Examining HPO by organ and system to facilitate practical use by clinicians
Published 2024-11-01“…Abstract The Human Phenotype Ontology (HPO) is widely used for annotating clinical text data, and sufficient annotation is crucial for the effective utilization of clinical texts. …”
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27872
Regularized Multiframe Super-Resolution Image Reconstruction Using Linear and Nonlinear Filters
Published 2021-01-01“…In this paper, we intend to enhance the efficiency of multiframe super-resolution image reconstruction in order to optimize both analysis and human interpretation processes by improving the pictorial information and enhancing the automatic machine perception. …”
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27873
3-Methyl-4-Nitrobenzoate Derivates as Antifungal Drug Candidates: Biological and In Silico Evaluation
Published 2025-01-01“…The Candida genus includes many opportunistic pathogens of great clinical importance, being commonly involved in several superficial and systemic human fungal infections. In this study, eleven 3-methyl-4-nitrobenzoate derivates were prepared and evaluated against four Candida strains (Candida albicans ATCC-90028, C. glabrata 90,030, C. krusei 34,125, and C. guilliermondii 207). …”
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27874
A review of deep learning in blink detection
Published 2025-01-01“…Blink detection is a highly concerned research direction in the field of computer vision, which plays a key role in various application scenes such as human-computer interaction, fatigue detection and emotion perception. …”
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27875
Copper Adsorption Using Hydroxyapatite Derived from Bovine Bone
Published 2022-01-01“…Copper-polluted groundwater poses a severe threat to human health and the ecological environment. Permeable reactive barrier (PRB) has been rapidly developed as the in situ remediation technology to control toxic copper migration. …”
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27876
Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells
Published 2025-01-01“…EV expression of LFA-1 increases EV binding to ICAM-1-expressing cells, an effect that was dose-dependently inhibited by a specific neutralizing ICAM-1 antibody. Further, activated human endothelial cells treated with LFA-1 EVMyd88 had increased uptake of these EVs, resulting in dose-dependent inhibition of induced release of IL-8, presumably by targeting Myd88. …”
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27877
In vivo evaluation of focused ultrasound ablation surgery (FUAS)-induced coagulation using echo amplitudes of the therapeutic focused ultrasound transducer
Published 2024-12-01“…On day 7, animals were sacrificed humanely, and the treated tissues were dissected to expose the lesion. …”
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27878
2D SnSe2 micro-flower decorated with 0D In2O3 nanoparticles for low-temperature low-concentration TEA detection
Published 2024-12-01“…Triethylamine, a crucial industrial raw material, poses significant threats to both the ecosystem and human health. However, detecting lower concentrations of TEA remains an arduous task. …”
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27879
Application of Neurochemical Markers for Assessing Health Effects after Developmental Methylmercury and PCB Coexposure
Published 2012-01-01“…All changes were caused by 1 MeHg mg/kg/day, the lower dose was ineffective. Human Data. Both biomarkers showed homogeneous distributions within the cohort (MRs, range 0.1–36.78 fmol/million cells; MAO-B, 0.95–14.95 nmol/mg protein/h). …”
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27880
Extraction and Characterization of Natural Coagulant Made from Banana Plant Stems (Musa acuminate) for the Removal of Turbidity from Wastewater
Published 2023-01-01“…Wastewater treatment with chemical coagulants has a variety of drawbacks, including sludge management, cost, concerns for human health, and environmental pollution. In light of this, a study was conducted to determine whether banana plant stem (Musa acuminate) made coagulant can effectively reduce turbidity (NTU) of wastewater. …”
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