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27541
Detection of N-Glycolyl GM3 Ganglioside in Neuroectodermal Tumors by Immunohistochemistry: An Attractive Vaccine Target for Aggressive Pediatric Cancer
Published 2011-01-01“…The N-glycolylated ganglioside NeuGc-GM3 has been described in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but is usually not detected in normal human cells. Our aim was to evaluate the presence of NeuGc-GM3 in pediatric neuroectodermal tumors by immunohistochemistry. …”
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27542
Gamification elements and online resources for teaching english lexics to future engineers at technical university
Published 2022-01-01“…The paper is devoted to gamification as one of the leading trends in all branches of human activity, including education. A modern young professional should have a formed foreign language communicative competence to perform professional duties in the most effective way. …”
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27543
Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries
Published 2025-01-01“…This threat is of particular concern in low- and middle-income countries (LMICs), where untreated effluents are often used for irrigating vegetables crops, leading to direct and indirect human exposure. Despite being a potential hotspot for the spread of antimicrobial resistance (AMR), existing HWW treatment systems in LMICs primarily target conventional pollutants and lack effective standards for monitoring the removal of ARB and ARGs. …”
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27544
HPV16 <em>E6</em> Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway
Published 2024-01-01“…Human Papillomaviruses have been associated with the occurrence of cervical cancer, the fourth most common cancer that affects women globally, while 70% of cases are caused by infection with the high-risk types HPV16 and HPV18. …”
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27545
Forest fire risk assessment model optimized by stochastic average gradient descent
Published 2025-01-01“…The model is based on the Regional Disaster System Theory (RDST), and incorporates 11 indicators of meteorological, vegetation, and human activity factors from the aspects of hazard-formative factor, hazard-formative environment, and hazard-affected body, and achieves a prediction accuracy of 94.38% and a coefficient of determination of 0.9581 when compared with historical data and the Global Fire Weather Index (FWI). …”
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27546
Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction
Published 2025-01-01“…We here investigated how endothelial aging impacts blood-brain barrier (BBB) function by using excision repair cross complementation group 1 (ERCC1)-deficient human brain ECs and an EC-specific Ercc1 knock out (EC-KO) mouse model. …”
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27547
Generic and vague uses of a second-person singular pronoun in an open-class person-reference system and speaker creativity in reported speech: the case of anata in Japanese
Published 2025-01-01“…This study demonstrates that the 2sg pronoun anata in Japanese is used to refer to people in general (‘generic’ use) or to human referents who are low in specificity (‘vague’ use). …”
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27548
GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial
Published 2019-01-01“…This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who are administered either gonadotropin-releasing hormone agonist (GnRHa) or human chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination (IUI) cycles. …”
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27549
Study of machine learning techniques for outcome assessment of leptospirosis patients
Published 2024-06-01“…The contribution of this article is the confirmation that artificial intelligence, using the Decision Tree model algorithm, depicting the best choice as the final model to be used in future data for the prediction of human leptospirosis cases, helping in the diagnosis and course of the disease, aiming to avoid the evolution to death.…”
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27550
Mathematical Modelling of Acetaminophen Release in HPC/PAAm Hydrogel: Synthesis and Application
Published 2019-01-01“…The release tests were performed for hypothermic, normal, and febrile human body conditions, at 35, 37, and 39°C, respectively, on two release media: water and phosphate buffer solution. …”
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27551
Propranolol: A Promising Therapeutic Avenue for Classic Kaposi Sarcoma
Published 2025-01-01“… Introduction: Kaposi sarcoma (KS) is a low grade angio-proliferative tumor of endothelial origin. Human herpes virus 8 (HHV8) plays a major role in the pathogenesis of KS. …”
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27552
Ozone oxidative preconditioning: a protection against cellular damage by free radicals
Published 1998-01-01“…There is some anecdotal evidence that oxygen-ozone therapy may be beneficial in some human diseases . However so far only a few biochemical and pharmacodynamic mechanisms have been elucidated. …”
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27553
Design of a Cost-Effective Ultrasound Force Sensor and Force Control System for Robotic Extra-Body Ultrasound Imaging
Published 2025-01-01“…Robot-assisted ultrasound may provide a solution by delivering more consistent, precise, and faster scans, potentially reducing human error and healthcare costs. Effective force control is crucial in robotic ultrasound scanning to ensure consistent image quality and patient safety. …”
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27554
Designing the Interventions to Mitigate the Barriers of Coordination in Handling Food Security: Insight from Central Java Province
Published 2022-01-01“…The result of the ISM method also indicated three “very significant” barriers: inadequate human resources, the limited capability of the regional government, and lack of communication and high specialization in multisector collaboration. …”
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27555
Incorporating circularity, sustainability, and systems thinking into an assessment framework for transformative food system innovation
Published 2025-01-01“…The transition towards a circular economy in the food system is posited as way to harmonize the provision safe, ample and accessible food to a growing population with the reduction the food system’s widespread impact on natural resources, the environment, and human health. Within the context of circular food innovation, there is an abundance of assessment approaches allowing researchers to evaluate and guide new technologies, applications, and products. …”
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27556
Tunes that move us: the impact of music-induced emotions on prosocial decision-making
Published 2025-01-01“…IntroductionThe significance of music might be attributed to its role in social bonding, a function that has likely influenced the evolution of human musicality. Although there is substantial evidence for the relationship between prosocial songs and prosocial behavior, it remains unclear whether music alone, independent of lyrics, can influence prosocial behaviors. …”
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27557
Effect of Maternal Administration of Edible Bird’s Nest on the Learning and Memory Abilities of Suckling Offspring in Mice
Published 2018-01-01“…Although human brains continue developing throughout the underage developmental stages, the infancy period is considered the most important one for the whole life. …”
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27558
Comparative evaluation of four exome enrichment solutions in 2024: Agilent, Roche, Vazyme and Nanodigmbio
Published 2025-01-01“…This study compares available to date four exome enrichment kits: Agilent SureSelect Human All Exon v8, Roche KAPA HyperExome, Vazyme VAHTS Target Capture Core Exome Panel, and Nanodigmbio NEXome Plus Panel v1. …”
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27559
Microbial Characteristics and Functions in Coffee Fermentation: A Review
Published 2024-12-01“…It is also beneficial for human health because of its rich active compounds, such as caffeine, chlorogenic acids, trigonelline, tryptophan alkaloids, diterpenes, melanoidins, etc. …”
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27560
AI-Driven Meat Food Drying Time Prediction for Resource Optimization and Production Planning in Smart Manufacturing
Published 2025-01-01“…Conventional approaches for estimating drying times often depend on empirical rules or manual observations, which can be time-consuming, subjective, and susceptible to human error. Therefore, implementing an automation solution by developing a predictive model for drying times in meat manufacturing is essential for optimizing the production lifecycle. …”
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