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27421
Effect of Pentoxifylline on Microalbuminuria in Diabetic Patients: A Randomized Controlled Trial
Published 2015-01-01“…Pentoxifylline is a nonspecific phosphodiesterase inhibitor with anti-inflammatory properties. Human studies have proved its antiproteinuric effect in patients with glomerular diseases, but this study was designed to assess the effects of add-on pentoxifylline to available treatment on reduction of microalbuminuria in diabetic patients without glomerular diseases. …”
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27422
Application of Artificial Intelligence in Academic Libraries
Published 2024-12-01“…The results revealed that barriers such as a lack of funding, expertise, and institutional support hinder wider adoption, along with concerns about AI’s impact on critical thinking and human roles. The lack of training and strategic planning around AI oversight may have contributed to the low response rate, complicating the drawing of firm conclusions. …”
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27423
Effect of Tumor Necrosis Factor Family Member LIGHT (TNFSF14) on the Activation of Basophils and Eosinophils Interacting with Bronchial Epithelial Cells
Published 2014-01-01“…In this study, we investigated the effects of LIGHT on the coculture of human basophils/eosinophils and bronchial epithelial BEAS-2B cells. …”
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27424
Formaldehyde Exposure and Its Potential Health Risk in Some Beauty Salons in Kumasi Metropolis
Published 2020-01-01“…In order to assess the exposure of cosmetologists to formaldehyde, the indoor air in sixty beauty salons across the ten submetros in Kumasi were sampled to determine the formaldehyde levels and the associated noncarcinogenic human health risks. Sampling was done using System Service Innovation Incorporation air sampler model 1000i, and the MBTH spectrophotometric method was used for analysis. …”
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27425
Exploring anti-cancer activities of epidermal growth factor-immobilized polymeric nanoparticles
Published 2025-02-01“…Initial mechanistic studies on phosphorylation signaling and cholesterol depletion revealed that EGF-polystyrene nanoparticles exhibited cytotoxicity against human cervical adenocarcinoma HeLa cells via local enhancement of EGFR activity in membrane rafts. …”
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27426
Sirtuin-2 Protects Neural Cells from Oxidative Stress and Is Elevated in Neurodegeneration
Published 2017-01-01“…SH-SY5Y viability in response to oxidative stress induced by diquat or rotenone was measured following SIRT2 overexpression or inhibition of deacetylase activity, along with α-synuclein aggregation. SIRT2 in human tissues was evaluated using Western blotting, immunohistochemistry, and fluorometric activity assays. …”
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27427
Employing the concept of stacking ensemble learning to generate deep dream images using multiple CNN variants
Published 2025-03-01“…Such approaches can also be useful for promoting interest in human artwork, particularly surrealist images. Accordingly, in the present, a stacking ensemble Deep Dream model was developed that aids psychiatrists and psychologists in addressing the challenge of mimicking hallucinations. …”
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27428
Application of deep learning techniques for analysis and prediction of particulate matter at Kota city, India
Published 2024-12-01“…Air pollution significantly threatens human health and the environment, making accurate prediction of pollutant concentrations crucial for effective mitigation. …”
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27429
A comparative cohort study of post-COVID-19 conditions based on physical examination records in ChinaResearch in context
Published 2025-02-01“…Standard physical examination data, comprising evaluations of nearly a hundred indicators, were investigated for a comprehensive assessment of COVID-19’s effect on human health. Findings: The results suggested that most indicators remained stable or changed within a permissible range after the COVID-19 outbreak in December 2022, but several specific indicators presented abnormal patterns of varying durations. …”
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27430
Effect of plasma assisted combustion on emissions of a premixed nitrous oxide fuel blend
Published 2025-03-01“…However, research on the fuel blend is relatively scant, especially regarding its emission characteristics, as the composition may produce high NOx emissions, which are harmful to both human society and the environment. This study sought to utilize Nanosecond Pulsed Dielectric Barrier Discharge plasma as an emission control mechanism as not only has it found success as a pollution control mechanism, but also as a combustion enhancement one. …”
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27431
Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention
Published 2025-02-01“…We conducted a multi-omic characterization of established VTX-resistant isogenic human myeloma cell lines (HMCL) and primary MM patient samples pre- and post-VTX treatment. …”
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27432
Toward <i>Mycobacterium tuberculosis</i> Virulence Inhibition: Beyond Cell Wall
Published 2024-12-01“…<i>Mycobacterium tuberculosis</i> (Mtb) is one of the most successful bacterial pathogens in human history. Even in the antibiotic era, Mtb is widespread and causes millions of new cases of tuberculosis each year. …”
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27433
Development of a Semiconductor Sequencing-based Panel for Screening Individuals with Lynch Syndrome
Published 2022-07-01“…The sensitivity and specificity of the identified mutations were determined by sequencing the serially diluted DNA from two human cancer cell lines, HCT 116 and LN-18. An average of 92 % of reads were mapped to the target region with 98 % uniformity. …”
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27434
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion.
Published 2025-01-01“…We show well-supported examples upstream of the Spike gene-within the nsp16 coding region of ORF1b-which is expressed during human infection, and upstream of the canonical Envelope gene TRS, both of which have evolved convergently in multiple lineages. …”
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27435
Case report: Patients with positive HER-2 amplification locally advanced gastroesophageal junction cancer achieved pathologic complete response with the addition of pembrolizumab t...
Published 2025-02-01“…BackgroundHuman epidermal growth factor receptor 2(HER-2) is the most prominent therapeutic target for gastric (G)/gastroesophageal junction (GEJ) cancer. …”
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27436
Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions
Published 2015-01-01“…Plasmablastic lymphoma (PBL) is an aggressive subtype of non-Hodgkin’s lymphoma (NHL), which frequently arises in the oral cavity of human immunodeficiency virus (HIV) infected patients. …”
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27437
Phonetic and Grammatical Characteristics of Mojtabā Minovi’s Pānzdah Goftār
Published 2024-10-01“…For example, he used feminine Arabic adjectives for broken/internal plural (jam'-e mokassar) or singular Arabic nouns, compound prepositions in their complete form, such as az baraye (for), dar tahte (under), and dar moghe-ye (while), singular verb for a non-human plural subject, descriptive (participial) form frequently, and other such characteristics.…”
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27438
BIOSYNTHESIS OF NANOPARTICLES FROM PLANT EXTRACTS AND THEIR APPLICATIONS IN MEDICAL TREATMENTS AND DRUG DELIVERY: A REVIEW
Published 2024-12-01“…Green chemistry methods are suitable for producing and processing hazardous chemicals that threaten human health and the environment. This technology requires extensive experience in dealing with the raw materials, especially in the elements and metals used to transform them into nanomaterials and the resulting side effects and chemical reactions. nanotechnology has achieved a systemic breakthrough and metal nanoparticles (green nanoparticles) have received much attention due to their physiological, technological and chemical differences. …”
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27439
Isolation, Identification, and Antimicrobial Study of Yersinia spp. Isolated from Traditional and Industrial Olivier Salad Specimens in Tehran
Published 2025-02-01“…The biotype of Yersinia enterocolitica was investigated, and three strains of biotype 1A and one strain of biotype 1B were identified. The human pathogenic serotype was not found in the serotype analysis. …”
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27440
Which curriculum components do medical students find most helpful for evaluating AI outputs?
Published 2025-02-01“…Abstract Introduction The risk and opportunity of Large Language Models (LLMs) in medical education both rest in their imitation of human communication. Future doctors working with generative artificial intelligence (AI) need to judge the value of any outputs from LLMs to safely direct the management of patients. …”
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