Multiscale Intermuscular Coupling Analysis via Complex Network-Based High-Order O-Information by Chang Yu, Qingshan She, Michael Houston, Tongcai Tan, Yingchun Zhang

“…Intermuscular coupling analysis (IMC) provides important clues for understanding human muscle motion control and serves as a valuable reference for the rehabilitation assessment of stroke patients. …”
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Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease by Lindsey Van Haute, Petra Páleníková, Jia Xin Tang, Pavel A Nash, Mariella T Simon, Angela Pyle, Monika Oláhová, Christopher A Powell, Pedro Rebelo-Guiomar, Alexander Stover, Michael Champion, Charulata Deshpande, Emma L Baple, Karen L Stals, Sian Ellard, Olivia Anselem, Clémence Molac, Giulia Petrilli, Laurence Loeuillet, Sarah Grotto, Tania Attie-Bitach, Jose E Abdenur, Robert W Taylor, Michal Minczuk

“…Abstract Pathogenic variants in either the mitochondrial or nuclear genomes are associated with a diverse group of human disorders characterized by impaired mitochondrial function. …”
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Activity of Phosvitin in Hydroxyapatite Acid-Damage Immersion and Antimicrobial Assays by Richard D. Shipman, Sean D. Doering, Jack R. Hemsath, Eun Joo Lee, Jennifer E. Grant

“…In both Kirby–Bauer tests and liquid culture growth inhibition assays, phosvitin inhibited M. luteus, a microorganism that thrives in the human mouth, but not the other bacteria tested. The MIC of phosvitin was determined to be 31.3 μg/mL when delivered in 1 mM CaCl2 but was 0.5 mg/mL in the absence of added calcium. …”
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Prion Diseases and the Gastrointestinal Tract by Gwynivere A Davies, Adam R Bryant, John D Reynolds, Frank R Jirik, Keith A Sharkey

“…The gastrointestinal (GI) tract plays a central role in the pathogenesis of transmissible spongiform encephalopathies. These are human and animal diseases that include bovine spongiform encephalopathy, scrapie and Creutzfeldt-Jakob disease. …”
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Serum Micronutrient Status of Haart-Naïve, HIV Infected Children in South Western Nigeria: A Case Controlled Study by H. C. Anyabolu, E. A. Adejuyigbe, O. O. Adeodu

“…Though micronutrients are vital in the pathogenesis of human immunodeficiency virus infection, most studies have been conducted in adults. …”
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MENTAL STATUS WITH SOCIAL INTERACTION CAPACITY IN THE ELDERLY AT SUKODADI COMMUNITY HEALTH CENTER, LAMONGAN DISTRICT by Khotibul Umam, Joko Susanto, Tantri Tristiana Dewi, Endah Sri Wijayanti, Lailatul Fadliyah

“…Introduction: In the human life cycle there is growth and development either physically and mentally. …”
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Prenatal Stress due to a Natural Disaster Predicts Adiposity in Childhood: The Iowa Flood Study by Kelsey N. Dancause, David P. Laplante, Kimberly J. Hart, Michael W. O’Hara, Guillaume Elgbeili, Alain Brunet, Suzanne King

“…Prenatal stress can affect lifelong physical growth, including increased obesity risk. However, human studies remain limited. Natural disasters provide models of independent stressors unrelated to confounding maternal characteristics. …”
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Enoch Olujide Gbadegesin, Yunusa Kehinde Salami and Kola Abimbola (eds.) Exploring the Ethics of Individualism and Communitarianism. Harvest Day Publications ,2016,365p. by Adeshina Afolayan

“…While some confronted some basic elements of his work, like chapter four (human personality), seven (work), and nine (destiny), other chapters took the thematic concerns of, say, communitarianism and ethics as the springboard for further reflections on corruption, nationalism and nation building, citizenship, religion, personhood, leadership, race, justice, gender and the nature of African philosophy. …”
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Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas. by Victoria E S Armero, Marie-Pier Tremblay, Andréa Allaire, Simon Boudreault, Camille Martenon-Brodeur, Cyntia Duval, Mathieu Durand, Elvy Lapointe, Philippe Thibault, Maude Tremblay-Létourneau, Jean-Pierre Perreault, Michelle S Scott, Martin Bisaillon

“…Multiple human diseases including cancer have been associated with a dysregulation in RNA splicing patterns. …”
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Different Pathological Roles of Toll-Like Receptor 9 on Mucosal B Cells and Dendritic Cells in Murine IgA Nephropathy by Tadahiro Kajiyama, Yusuke Suzuki, Masao Kihara, Hitoshi Suzuki, Satoshi Horikoshi, Yasuhiko Tomino

“…We have reported that mucosal toll-like receptor (TLR)-9 is involved in the pathogenesis of human and murine IgAN. However, cell-type expressing TLR9 in mucosa remains unclear. …”
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Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review by Ke Chen, Boyang Jiang, Boyang Jiang, Huiping Yan, Huiping Yan, Liu Yang, Liu Yang, Zheling Chen, Zheling Chen

“…In clinical use, bevacizumab has improved the overall survival (OS) and progression-free survival (PFS) of malignant solid tumors, and the safe use of bevacizumab has gradually become the mainstream direction of clinical, nursing and pharmaceutical research. Bevacizumab is a humanized anti-VEGF drug. By binding to VEGF, it loses the opportunity to activate VEGFR and then plays an anti-angiogenic role. …”
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Autologous and Heterologous Minor and Major Bone Regeneration with Platelet-Derived Growth Factors by Gianna Dipalma, Angelo Michele Inchingolo, Valeria Colonna, Pierluigi Marotti, Claudio Carone, Laura Ferrante, Francesco Inchingolo, Andrea Palermo, Alessio Danilo Inchingolo

“…Only English-language clinical studies involving human subjects were included. A total of 10 studies were selected for qualitative analysis. …”
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Sulforaphane in alternative cancer chemotherapy: From carcinogenesis suppression to drug resistance reversal by Seyed Mohammad Doodmani, Payman Rahimzadeh, Najma Farahani, Seyedalireza Mirilavasani, Mina Alimohammadi, Noushin Nabavi, Elmira Alaei, Afshin Taheriazam, Maryam Abedi, Nadia Shafiee, Salman Daneshi, Mehrdad Hashemi

“…When combined with chemotherapy drugs, SFN enhances tumor suppression and mitigates drug resistance in human cancers. This is achieved primarily by promoting apoptosis, reducing proliferation, and inhibiting metastasis. …”
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Climate change and migration dynamics in Somalia: a time series analysis of environmental displacement by Abdikadir Ahmed Mohamed, Ibtisam Mohamed Omar, Abdi Majid Yusuf Ibey, Mahdi Mohamed Omar

“…Climate change is a significant driver of human migration, especially in vulnerable regions like Somalia. …”
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Functional connectome gradient of prefrontal cortex as biomarkers of high risk for internet gaming disorder by Xinwen Wen, Lirong Yue, Zhe Du, Jiahao Zhao, Mengjiao Ge, Cunfeng Yuan, Hongmei Wang, Qinghua He, Kai Yuan

“…We used functional connectome gradient (FCG) to capture the macroscopic hierarchical organization of human brain. Canonical correlation analysis was employed to identify components mapping relationships between FCG and behavioral scores. …”
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Statistical Distribution of Urban Area Reveals a Converging Trend of Global Urban Land Expansion by Shengjie Hu, Zhenlei Yang, Sergio Andres Galindo Torres, Zipeng Wang, Haoying Han, Yoshihide Wada, Thomas Cherico Wanger, Ling Li

“…Abstract Urban land expansion is a major driver of many environmental and societal changes that challenge human well‐being and sustainable development, but its evolutionary process and dynamics are neither clear nor well‐integrated into urban science quantitatively. …”
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From Bench to Brain: A Metadata-driven Approach to Research Data Management in a Collaborative Neuroscientific Research Center by Marlene Pacharra, Tobias Otto, Nina Olivia Caroline Winter

“…Using this metadata schema, neuroscientific data from more than 3,200 human subjects and lab animals are currently shared within the CRC. …”
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Urinary Microvesicle-Bound Uromodulin: A Potential Molecular Biomarker in Diabetic Kidney Disease by Neng-jun Lou, Yi-hong Ni, Hong-ying Jia, Jing-ti Deng, Lu Jiang, Feng-jie Zheng, Ai-li Sun

“…This study was designed to investigate the changes of urinary microvesicle-bound uromodulin and total urinary uromodulin levels in human urine and the correlations with the severity of diabetic kidney disease (DKD). 31 healthy subjects without diabetes and 100 patients with type 2 diabetes mellitus (T2DM) were included in this study. …”
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Point of Care Perioperative Coagulation Management in Liver Transplantation and Complete Portal Vein Thrombosis by Cristiano Piangatelli, Lucia Faloia, Claudia Cristiani, Ilaria Valentini, Marco Vivarelli

“…Based on ROTEM findings, the patient received 16 g of human fibrinogen concentrate, half preoperatively (with prothrombin complex concentrate 2000 IU, tranexamic acid 1 g, and platelets 2 IU), and two doses of 4 g before and after graft reperfusion; we achieved normalization of all monitored parameters. …”
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Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin by Hsu-Lung Jen, Po-Len Liu, Yung-Hsiang Chen, Wei-Hsian Yin, Jaw-Wen Chen, Shing-Jong Lin

“…The purpose of this study was to evaluate the effect of PPARα activation on endothelin-1- (ET-1-) caused cardiomyocyte hypertrophy and explore its underlying mechanisms. Human cardiomyocytes (HCMs) were cultured with or without ET-1, whereafter the inhibitory effects of fenofibrate, a PPARα activator, on cell size and adiponectin protein were tested. …”
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