Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells by Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki

“…In this study, we aimed to examine the anti-inflammatory effects of nobiletin on tumor necrosis factor- (TNF-) stimulated human periodontal ligament cells (HPDLCs). Our results demonstrated that nobiletin treatment could decrease the expressions of inflammatory cytokines (C-X-C motif chemokine ligand (CXCL)10, C-C motif chemokine ligand (CCL)2, and interleukin- (IL-) 8), matrix metalloproteinases (MMPs) (MMP1 and MMP3), and prostaglandin-endoperoxide synthase 2 (PTGS2) in TNF-stimulated HPDLCs. …”
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Critical linkages between land use change and human health in the Amazon region: A scoping review. by Molly Mastel, Alejandra Bussalleu, Valerie A Paz-Soldán, Gabriela Salmón-Mulanovich, Armando Valdés-Velásquez, Stella M Hartinger

“…Our research aims to examine the current state of evidence on the link between LUC and human health in the Amazon region. We conducted a scoping review of literature in two research databases, resulting in 14 papers for analysis. …”
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In defence of South Africa’s National Health Research Ethics Council guidelines on heritable human genome editing by Donrich Thaldar, Sheetal Soni, Larisse Prinsen, Ntokozo Mnyandu, Marietjie Botes, Julian Kinderlerer

Subjects: “…heritable human genome editing…”
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VEGF Promotes Proliferation of Human Glioblastoma Multiforme Stem-Like Cells through VEGF Receptor 2 by Chengshi Xu, Xing Wu, Jianhong Zhu

“…In this study, human GBSCs were isolated from surgical specimens of glioblastoma and cultured in medium favored for stem cell growth. …”
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Analysis of Drug Effects on Primary Human Coronary Artery Endothelial Cells Activated by Serum Amyloid A by K. Lakota, D. Hrušovar, M. Ogrič, K. Mrak-Poljšak, S. Čučnik, M. Tomšič, B. Božič, P. Žigon, S. Sodin-Semrl

“…To determine the effects of medications on SAA-stimulated human coronary artery endothelial cells (HCAEC). …”
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Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

“…We used Google Scholar, Pubmed, and Biomed Central databases for searching peer-reviewed literature in human, animal and environment sectors during January 2010-August 2019, and Google for grey materials from the institutional and journal websites. …”
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New discoveries of Middle Paleolithic human remains from the “Bau de l'Aubésier (Vaucluse, France)” by Serge Lebel, Erik Trinkaus

“…The Middle Pleistocene remains (Aubesier 10 and 11) have close morphological affinities to contemporaneous European human remains, and the Neandertal molar (Aubesier 12) falls well within Neandertal ranges of variation. …”
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Heavy chain-only antibodies with a stabilized human VH in transgenic chickens for therapeutic antibody discovery by Christine N. Vuong, Kevin M. Reynolds, Gerry S. Rivera, Baisen Zeng, Zahra Karimpourkalou, Manith Norng, Yulei Zhang, Robayet Chowdhury, Darlene Pedersen, Melissa Pantoja, Ellen Collarini, Swetha Garimalla, Shelley Izquierdo, Eric G. Vajda, Brett Antonio, Devendra B. Srivastava, Marie-Cecile van de Lavoir, Yasmina Abdiche, William Harriman, Philip A. Leighton

“…We have developed transgenic chickens expressing heavy chain-only antibodies with a human variable region to combine the superior target recognition advantages of a divergent, non-mammalian host with the ability to discover single-domain binders. …”
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Perancangan Pengalaman Pengguna Portal Job Fair Sarjana Sakti dengan Pendekatan Human-Centered Design by Annisah Amalia, Herman Tolle, Ratih Kartika Dewi

“…Aplikasi ini dirancang dengan menggunakan pendekatan Human-Centered Design (HCD) karena memiliki strategi desain yang iterative untuk mendapatkan hasil yang diharapkan. …”
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Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes by Ehsan Zamani, Alireza Ahmadi Shad, Hediye Fatemi, Saba Mahboubi, Azadeh Motavallian, Mehdi Evazalipour

“…Therefore, using carvacrol as a natural antioxidant protected human lymphocytes against haloperidol genetic damage.…”
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TNF-α Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B by Letizia Mezzasoma, Lucio Cagini, Cinzia Antognelli, Francesco Puma, Eugenio Pacifico, Vincenzo Nicola Talesa

“…Here, we showed that TNF-α selectively regulates key molecules involved in fluids balance, such as natriuretic peptides (NPs) and aquaporins, in human bronchial epithelial cells BEAS-2B. In particular, we found that TNF-α induced a decrease of arial natriuretic peptide, natriuretic peptide receptor-1, aquaporin-1 and aquaporin-5 and an increase of brain natriuretic peptide with a different involvement of nuclear factor-κB and mitogen-activated protein kinases signaling pathway activation. …”
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Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics by Xi Yang, Xuemin Chen, Wei Yang, Yves Pommier

“…We present a series of cryo-EM structures of human TOP3B with its cofactor TDRD3 during cleavage and rejoining of DNA or RNA, thus elucidating the roles of divalent metal ions and key enzyme residues in each step of the catalytic cycle. …”
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Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages by Mariarosaria Napolitano, Howard S. Kruth, Elena Bravo

“…To investigate these mechanisms, triacylglycerol (TG) accumulation induced by apolipoprotein-free chylomicron remnant-like particles (CRLPw/o) in human monocyte-derived macrophages was evaluated. …”
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Silent Human Trypanosoma brucei gambiense Infections around the Old Gboko Sleeping Sickness Focus in Nigeria by Karshima Solomon Ngutor, Lawal A. Idris, Okubanjo Oluseyi Oluyinka

“…Trypanosoma brucei gambiense causes Gambian trypanosomosis, a disease ravaging affected rural parts of Sub-Saharan Africa. We screened 1200 human blood samples for T. b. gambiense using the card agglutination test for trypanosomosis, characterized trypanosome isolates with Trypanosoma gambiense serum glycoprotein-PCR (TgsGP-PCR), and analyzed our data using Chi square and odds ratio at 95% confidence interval for statistical association. …”
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Calcium Transient and Sodium-Calcium Exchange Current in Human versus Rabbit Sinoatrial Node Pacemaker Cells by Arie O. Verkerk, Marcel M. G. J. van Borren, Ronald Wilders

“…However, when compared to the diastolic net membrane current, INaCa is of similar size in human and rabbit SAN pacemaker cells, whereas If is smaller in human than in rabbit cells.…”
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Effect in vitro of the Phenobarbital on the Activity of the Enzyme Adenosine Triphosphatase (ATPase) of Sodium and Potassium Dependent in Human Placenta. by María De Jesús Sánchez Bouza, Pedro Sánchez Frenes

“…<strong>Objective:</strong> To evaluate the effect in vitro of Phenobarbital on the activity of adenosine triphosphatase of sodium and potassium dependent in human placenta. <strong>Method: </strong>A study in vitro was carried out, in total homogenizes of placentas coming from 30 mothers that were assisted in the Gynecological and Obstetric Educational Provincial Hospital ¨Mariana Grajales¨, in Santa Clara, during the period March-July 1993. …”
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Release of Inflammatory Mediators by Human Adipose Tissue Is Enhanced in Obesity and Primarily by the Nonfat Cells: A Review by John N. Fain

“…In contrast, the circulating levels of leptin and FABP-4 are also enhanced in obesity and they are primarily released by fat cells of human adipose tissue. The relative expression of adipokines and other proteins in human omental as compared to subcutaneous adipose tissue as well as their expression in the nonfat as compared to the fat cells of human omental adipose tissue is also reviewed. …”
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Human Control Law and Brain Activity of Voluntary Motion by Utilizing a Balancing Task with an Inverted Pendulum by Satoshi Suzuki, Fumio Harashima, Katsuhisa Furuta

“…Advances in Human-Computer Interaction…”
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Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization by Peng-Chao Wang, Jie Liu, Yue-Fang Liu, Yang Wu, Lin-Li Xue, Zhen-Shan Yang

“…Under human in vitro decidualization, mPGES1 significantly increases, while both cPGES and mPGES2 remain unchanged. …”
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Factors influencing breast milk donation to a human milk bank in Iran: implications for policymakers and planners by Leila Doshmangir, Maryam Naghshi, Kamal Gholipour, Ayat Ahmadi, Hosein Azizi, Vladimir Sergeevich Gordeev

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