Protocol for the generation of HLF+ HOXA+ human hematopoietic progenitor cells from pluripotent stem cells by Sherry Li Zheng, Jonas L. Fowler, Julie Y. Chen, Christopher Li, Elaine Lin, Alana T. Nguyen, Angela Chen, George Q. Daley, Lay Teng Ang, Kyle M. Loh

“…Here, we present a protocol to differentiate human pluripotent stem cells (hPSCs) into hematopoietic progenitors that express the signature HSC transcription factors HLF, HOXA5, HOXA7, HOXA9, and HOXA10. hPSCs are dissociated, seeded, and then sequentially differentiated into posterior primitive streak, lateral mesoderm, artery endothelium, hemogenic endothelium, and hematopoietic progenitors through the sequential addition of defined, serum-free media. …”
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The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases by Faris Azzouni, Alejandro Godoy, Yun Li, James Mohler

“…Despite the discovery of 5 alpha-reduction as an enzymatic step in steroid metabolism in 1951, and the discovery that dihydrotestosterone is more potent than testosterone in 1968, the significance of 5 alpha-reduced steroids in human diseases was not appreciated until the discovery of 5 alpha-reductase type 2 deficiency in 1974. …”
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Exploring the Gating Mechanism of the Human Copper Transporter, hCtr1, Using EPR Spectroscopy by Shahaf Peleg, Shelly Meron, Yulia Shenberger, Lukas Hofmann, Lada Gevorkyan-Airapetov, Sharon Ruthstein

“…While structural details of the transmembrane domain of human Ctr1 have been elucidated using X-ray crystallography and cryo-EM, the transfer mechanisms of copper and the conformational changes that control the gating mechanism remain poorly understood. …”
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Cover: Properties of Human Colonic Myenteric Neurons Differ Depending on Age, Disorder, and Colonic Region

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Implication of tumor morphology and MRI characteristics on the accuracy of automated versus human segmentation of GBM areas by Valeria Cerina, Chiara Benedetta Rui, Andrea Di Cristofori, Davide Ferlito, Giorgio Carrabba, Carlo Giussani, Gianpaolo Basso, Elisabetta De Bernardi

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A hybrid human fall detection method based on modified YOLOv8s and AlphaPose by Lei Liu, Yeguo Sun, Yinyin Li, Yihong Liu

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Penetration of Silver Diamine Fluoride in Deep Carious Lesions of Human Permanent Teeth: An In Vitro Study by Jutharat Manuschai, Supitcha Talungchit, Supawadee Naorungroj

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Deciphering Uttarakhand's human efforts towards the ecology through Gross Environment Product (GEP) calculations by Anil Prakash Joshi, Shivam Joshi, Ramesh Kumar Sudhanshu, Durgesh Pant, Sushil Rai, Atul Rawat, Himani Purohit

“…This study presents an assessment of the Gross Environment Product (GEP) in Uttarakhand, India, evaluating the region's human efforts towards the ecology. Research examines the human efforts being made towards Uttarakhand's air, water, soil, and forest, balancing economic development with environmental sustainability. …”
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Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer by Juan José Mora Román, Miguel Del Campo, Javiera Villar, Francesca Paolini, Gianfranca Curzio, Aldo Venuti, Lilian Jara, Jorge Ferreira, Paola Murgas, Alvaro Lladser, Augusto Manubens, María Inés Becker

“…Due to the aggressiveness and deadly malignant potential of this cancer, the hemocyanins were applied in combination with adjuvants, such as alum, AddaVax, and QS-21, which have been shown to be safe and effective in human vaccines, to potentiate their antitumor activity. …”
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A short investigation of the effect of the selection of human brain atlases on the performance of ASD's classification models by Naseer Ahmed Khan, Xuequn Shang

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Isolation and Characterization of Human Synovial Fluid-Derived Mesenchymal Stromal Cells from Popliteal Cyst by Fang Li, Jianglin Chen, Mengjia Gong, Yang Bi, Chengchen Hu, Yuanyuan Zhang, Ming Li

“…Antibody detection of human angiogenesis-related proteins was performed compared with bone marrow mesenchymal stem cells (BM-MSCs). …”
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Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation by Ren-Shi Shyu, Themmila Khamrang, Joen-Rong Sheu, Chih-Wei Hsia, Marappan Velusamy, Chih-Hsuan Hsia, Duen-Suey Chou, Chao-Chien Chang

“…Ir-6 exhibited higher potency against human platelet aggregation stimulated by collagen. …”
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Effects of Changes in Osmolarity on the Biological Activity of Human Normal Nucleus Pulposus Mesenchymal Stem Cells by Hua Zhang, Wei Li, YaoHong Wu, Shengquan Zhang, Jie Li, Letian Han, Haoyu Chen, Ziyu Wang, Cailiang Shen, Yinshun Zhang, Hui Tao

“…In this study, we observed the effect of different osmolarities on the biological characteristics of human normal NPMSCs cultured in vitro and explored the role of osmolarity in intervertebral disc degeneration. …”
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A Human-Computer Interaction System for Agricultural Tools Museum Based on Virtual Reality Technology by Ying Yang, Yiyi Fan, Ruizhi Sun

“…To address the problems of rigid interaction and terrible experience in the process of human-computer interaction, four human-computer interaction technologies are proposed to design and construct a more humanized system including intelligent scenes switching technology, multichannel introduction technology, interactive virtual roaming technology, and task-based interactive technology. …”
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Cervical Spine Mechanism for Reproduction of the Biomechanical Behaviours of the Human Neck during Rotation-Traction Manipulation by Yuancan Huang, Shuai Li, Minshan Feng, Liguo Zhu

“…Therefore, we developed a cervical spine mechanism that imitates the dynamic behaviours of the human neck during RT manipulation. First, in vivo and in vitro experiments were performed to acquire the biomechanical feature curves of the human neck during RT manipulation. …”
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Characterization of microplastics in human follicular fluid and assessment of their potential impact on mouse oocyte maturation in vitro by Danyu Ni, Kaidi Yu, Nan Yan, Xiaojiao Chen, Qijun Xie, Yuqin Yang, Wei Jiang, Ye Yang, Junqiang Zhang, Xiufeng Ling

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Oxidative Coupling Assay for Mesalazine Determination in Pharmaceuticals and Spiked Human Plasma Utilizing Syringic Acid by Suzan S. Taha, Diyar S. Ali

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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution by Nicolas Tessandier, Baptiste Elie, Vanina Boué, Christian Selinger, Massilva Rahmoun, Claire Bernat, Sophie Grasset, Soraya Groc, Anne-Sophie Bedin, Thomas Beneteau, Marine Bonneau, Christelle Graf, Nathalie Jacobs, Tsukushi Kamiya, Marion Kerioui, Julie Lajoie, Imène Melki, Jean-Luc Prétet, Bastien Reyné, Géraldine Schlecht-Louf, Mircea T. Sofonea, Olivier Supplisson, Chris Wymant, Vincent Foulongne, Jérémie Guedj, Christophe Hirtz, Marie-Christine Picot, Jacques Reynes, Vincent Tribout, Édouard Tuaillon, Tim Waterboer, Michel Segondy, Ignacio G. Bravo, Nathalie Boulle, Carmen Lía Murall, Samuel Alizon

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Phosphate-modified CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells by A. A. Ostanin, O. Y. Leplina, E. A. Burakova, T. V. Tyrinova, A. A. Fokina, A. S. Proskurina, S. S. Bogachev, D. A. Stetsenko, E. R. Chernykh

“…The data obtained indicate a stimulating effect of CpG-ODN on the maturation and allostimulatory activity of human myeloid DCs, which is more pronounced for μ-modified analogs.…”
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Human Papilloma Virus Infection in Patients with Male Accessory Gland Infection: Usefulness of the Ultrasound Evaluation by Rosita A. Condorelli, Enzo Vicari, Laura M. Mongioi, Giorgio I. Russo, Giuseppe Morgia, Sandro La Vignera, Aldo E. Calogero

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