Downregulation of the keratins CK13 and CK14 does not significantly affect cell viability of human urinary bladder carcinoma cells by Anna Scherping, Antje Schinlauer, Piotr Czapiewski, Christoph Garbers

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A human oral commensal-mediated protection against Sjögren’s syndrome with maintenance of T cell immune homeostasis and improved oral microbiota by Yu-Chao Tseng, Kai-Sheng Liao, Wei-ting Lin, Chin Li, Chia-Bin Chang, Jie-Wei Hsu, Chin-Pui Chan, Chun-Ming Chen, Hon-Pin Wang, Hsiu-Chuan Chien, Jann-Tay Wang, Song-Chou Hsieh, Shu-Fen Wu

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Cytotoxic effect of 1% and 3% Sodium hypochlorite as irrigation agent in primary teeth on human red blood cells: an in vitro study by Divya Mukundan, Maria Anthonet Sruthi

“…In order to evaluate the cytotoxicity potential, fresh human blood was collected from a single healthy individual and subjected to testing. …”
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Burden of type 2 diabetes and its relationship with human development index in Asian countries: Global Burden of Disease Study in 2019 by Seyed Ahmadreza Alinaghian, Shokoufeh Hamidzadeh, Afsaneh Badrizadeh, Zaher Khazaei, Amirhossein Souri, Victoria Momenabadi, Elham Goodarzi

“…Results The results indicated that the human development index (HID) was positively and significantly correlated with the incidence of type 2 diabetes in men (r = 0.481, P < 0.05) and women (r = 0.414, P < 0.05, but the correlation between death and the HDI was not significant in men and women (P > 0.05). …”
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The Critical Role of YAP/BMP/ID1 Axis on Simulated Microgravity‐Induced Neural Tube Defects in Human Brain Organoids by Di Guo, Bin Yao, Wen‐Wei Shao, Jia‐Chen Zuo, Zhe‐Han Chang, Jian‐Xin Shi, Nan Hu, Shuang‐Qing Bao, Meng‐Meng Chen, Xiu Fan, Xiao‐Hong Li

“…In this study, the effects of stimulated microgravity (SMG) on the development of human brain organoids are investigated. SMG impairs N‐cadherin‐based adherens junction formation, leading to neural tube defects associated with dysregulated self‐renewal capacity and neuroepithelial disorganization in human brain organoids. …”
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Human Mesenchymal Stromal Cells Transplantation May Enhance or Inhibit 4T1 Murine Breast Adenocarcinoma through Different Approaches by T. Jazedje, A. L. Ribeiro, M. Pellati, H. M. de Siqueira Bueno, G. Nagata, M. Trierveiler, E. G. Rodrigues, M. Zatz

“…In an attempt to clarify the contradictory results reported in the literature and the possible role of human fallopian tube Mesenchymal Stromal Cells (htMSCs) against breast cancer, the aim of this study was to evaluate the clinical effect of htMSCs in murine mammary adenocarcinoma using two different approaches: (1) coinjections of htMSCs and 4T1 murine tumor cell lineage and (2) injections of htMSCs in mice at the initial stage of mammary adenocarcinoma development. …”
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Value of Humanized Nursing under Emergency Green Channel on Gastrointestinal Function Recovery in Patients with Acute Intestinal Obstruction after Operation by Siqi Luo, Yan Wang

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Quercetin Protects Primary Human Osteoblasts Exposed to Cigarette Smoke through Activation of the Antioxidative Enzymes HO-1 and SOD-1 by Karl F. Braun, Sabrina Ehnert, Thomas Freude, José T. Egaña, Thilo L. Schenck, Arne Buchholz, Andreas Schmitt, Sebastian Siebenlist, Lilianna Schyschka, Markus Neumaier, Ulrich Stöckle, Andreas K. Nussler

“…Our results demonstrate that CSM damages human osteoblasts by accumulation of ROS. Quercetin can diminish this damage by scavenging the radicals and by upregulating the expression of HO-1 and SOD-1. …”
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Development and evaluation of a recombinant monoclonal human antibody with virus-neutralizing activity against the F glycoprotein of respiratory syncytial virus by Sergey A. Klotchenko, Ekaterina A. Romanovskaya-Romanko, Marina A. Plotnikova, Anastasia A. Pulkina, Aram A. Shaldzhyan, Dmitry S. Balabashin, Victoria A. Toporova, Teimur K. Aliev, Natalia E. Gyulikhandanova, Dmitry A. Lioznov

“…Developing a therapy based on recombinant human antibodies to block the RSV fusion (F) glycoprotein is urgent to reduce the incidence of RSV infections and prevent associated complications. …”
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Corrigendum to “Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines” by Wilfredo Hernández, Juan Paz, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Jorge Manzur, Lothar Hennig, Joachim Sieler, Steffen Blaurock, Lothar Beyer

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Implementation strategies to increase human papillomavirus vaccination uptake for adolescent girls in sub-Saharan Africa: A scoping review protocol. by Mwansa Ketty Lubeya, Mulindi Mwanahamuntu, Carla Chibwesha, Moses Mukosha, Mercy Monde Wamunyima, Mary Kawonga

“…<h4>Introduction</h4>The human papillomavirus (HPV) is sexually transmitted and infects approximately 75% of sexually active people early in their sexual life. …”
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In vitro Effect of Low-level Lasers on Proteomic Concentration in Human Blood Plasma Using 375 nm and 650 nm Lasers by Ahmed Abdulkareem Al-Kaabi, Mustafa Al-Mosawi, Ali Abdullateef Abdulateef Al-Bayati

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Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…The validated method was successfully used to measure salvianolic acid B, acetylsalicylic acid, and salicylic acid concentrations in human plasma samples from 16 patients to observe the pharmacokinetic changes caused by DDIs.…”
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Lectins from the Red Marine Algal Species Bryothamnion seaforthii and Bryothamnion triquetrum as Tools to Differentiate Human Colon Carcinoma Cells by Vicente P. T. Pinto, Henri Debray, Danuta Dus, Edson H. Teixeira, Taianá Maia de Oliveira, Victor Alves Carneiro, Alrieta H. Teixeira, Gerardo C. Filho, Celso S. Nagano, Kyria S. Nascimento, Alexandre H. Sampaio, Benildo S. Cavada

“…The carbohydrate-binding activity of the algal lectins from the closely related red marine algal species Bryothamnion triquetrum (BTL) and Bryothamnion seaforthii (BSL) was used to differentiate human colon carcinoma cell variants with respect to their cell membrane glyco-receptors. …”
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Imaging of Myocardial Ischemia–Reperfusion Injury Using Sodium [F]Fluoride Positron Emission Tomography/Computed Tomography in Rats and Humans by Hongyoon Choi MD, PhD, Jeong Hee Han PhD, Sue Yeon Lim MS, Inki Lee MD, Young-Seok Cho MD, PhD, Eun Ju Chun MD, PhD, Won Woo Lee MD, PhD

“…We investigated Na[ 18 F]F uptake in ischemia–reperfusion injury (IRI) of rats and humans. Sodium [ 18 F]fluoride PET/CT was performed in Sprague-Dawley rats that had IRI surgery, and it readily demonstrated prominent Na[ 18 F]F uptake in the infarct area post-IRI. …”
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Human Aortic Endothelial Cell Labeling with Positive Contrast Gadolinium Oxide Nanoparticles for Cellular Magnetic Resonance Imaging at 7 Tesla by Yasir Loai, Nurus Sakib, Rafal Janik, Warren D. Foltz, HL Cheng

“…Relaxivity measurements yielded r 1 = 4.7 s −1 mM −1 and r 2 / r 1 = 6.2. Human aortic endothelial cells were labeled with Gd 2 O 3 at various concentrations and underwent MRI from 1 to 7 days postlabeling. …”
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From Waste to Innovation: A Circular Economy Approach for Tissue Engineering by Transforming Human Bone Waste into Novel Collagen Membranes by Lorena Gallego, Kimberly Harvey, Marta Pevida, Luis García-Consuegra, Olivia García-Suárez, Álvaro Meana, María Alvarez-Viejo, Luis Junquera

“…The purpose of the study is to manufacture a novel human-purified type I collagen membrane from bone remnants typically discarded during the processing of cortico-cancellous bones in tissue banks and to evaluate its mechanical properties and effectiveness in regenerating bone-critical mandibular defects in rabbits. …”
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Elucidating the Role of HIF-1&alpha;/YAP Signaling Pathway in Regulating Inflammation in Human Periodontal Stem Cells: An in vitro Study by Zhao HW, Liu ST, Wang XJ, Zhang XM, Ma X

“…This study investigated the effects of the prolyl hydroxylase (PHD) inhibitor DMOG on pro-inflammatory cytokine expression in human periodontal ligament stem cells (hPDLSCs) and examined the involvement of the HIF-1α/YAP signaling path ay in modulating inflammation.Materials and Methods: hPDLSCs were cultured and treated with lipopolysaccharide (LPS) to induce inflammation, followed by DMOG treatment. …”
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Exosomal MicroRNAs Derived from Human Amniotic Epithelial Cells Accelerate Wound Healing by Promoting the Proliferation and Migration of Fibroblasts by Bin Zhao, Xiaodong Li, Xiaomin Shi, Xueqin Shi, Wei Zhang, Gaofeng Wu, Xujie Wang, Linlin Su, Dahai Hu

“…Previous work in our laboratory demonstrated that exosomes derived from human amniotic epithelial cells (hAECs) accelerated wound healing by promoting the proliferation and migration of fibroblasts. …”
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Rapid Sampling of Large Quantities of Interstitial Fluid from Human Skin Using Microneedles and a Vacuum-assisted Skin Patch by Elizabeth Wilkirson, Xue Jiang, Peter Lillehoj

“…Here, we present step-by-step protocols for fabricating the MN array and skin patch, as well as for using them to sample ISF from human skin. Using this technique, an average of 20.8 μL of dermal ISF can be collected within 25 min, which is a ∼6-fold improvement over existing ISF sampling methods. …”
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