Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat by Chaojiang Li, Yuxuan Liu, Guodong Liu, Qifeng Tan, Xiaolong Dou, Yuting Xie, Xianchao Zhang

“…By comparing the detection results with those obtained from ion chromatography, the flexible potentiometric detector is proved to be useful for a real-time, on-body quantitative analysis of various ion concentrations in human sweat.…”
Get full text

An Efficient Algorithm for EM Scattering from Anatomically Realistic Human Head Model Using Parallel CG-FFT Method by Lei Zhao, Gen Chen

Get full text

Angiogenin Reduces Immune Inflammation via Inhibition of TANK-Binding Kinase 1 Expression in Human Corneal Fibroblast Cells by Seung Hoon Lee, Kyoung Woo Kim, Kyong-Mi Min, Kyu-Wan Kim, Soo-Ik Chang, Jae Chan Kim

Get full text

Technological progress, human capital, and employment rate: an empirical analysis using P-ARDL models from 1960-2019 by DAISY CAROLINE NASCIMENTO PEREIRA, GUILHERME JONAS COSTA DA SILVA

Subjects: Get full text

Enhanced Osteogenic and Vasculogenic Differentiation Potential of Human Adipose Stem Cells on Biphasic Calcium Phosphate Scaffolds in Fibrin Gels by Fransisca A. S. van Esterik, Behrouz Zandieh-Doulabi, Cornelis J. Kleverlaan, Jenneke Klein-Nulend

“…We aimed to test the osteogenic and/or vasculogenic differentiation potential as well as degradation of composites consisting of human adipose stem cells (ASCs) seeded on BCP60/40 or BCP20/80 incorporated in fibrin gels that trigger neovascularization for bone regeneration. …”
Get full text

Protocol for differentiating cardiomyocytes and generating engineered heart tissues from human feeder-free extended pluripotent stem cells by Zhongjun Wan, Shanshan Wen, Ran Zheng, Li Li, Wei Jiang, Donghui Zhang

“…We describe steps for converting human embryonic stem cells or induced pluripotent stem cells (ESCs/iPSCs) into ffEPSCs, followed by their long-term maintenance, cryopreservation, seed preservation, and differentiation into cardiomyocytes. …”
Get full text

Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination by Henry M. Vu, Thomas E. Moran, Zhong Liang, Yun-Juan Bao, Paulina G. Carles, Jessica C. Keane, Madelyn G. Cerney, Caitlyn N. Dahnke, Ana L. Flores-Mireles, Victoria A. Ploplis, Francis J. Castellino, Shaun W. Lee

“…ABSTRACT Group A Streptococcus (GAS) is a major human pathogen that causes several invasive diseases including necrotizing fasciitis. …”
Get full text

Human Tyrosinase Displayed on the Surface of Chinese Hamster Ovary Cells for Ligand Fishing of Tyrosinase Inhibitors from Medicinal Plants by Xiao-Rui Zhai, Ming-Jie Li, Xiang Yin, Ayzohra Ablat, Yuan Wang, Peng Shu, Xun Liao

“…Ligand fishing is a promising strategy for the screening of active ingredients from complex natural products. In this work, human tyrosinase (hTYR) was displayed on the surface of Chinese hamster ovary (CHO) cells for the first time; it was then used as bait to develop a new method for ligand fishing. …”
Get full text

Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants by Michelle R. Garnsey, Yang Wang, David J. Edmonds, Matthew F. Sammons, Benjamin Reidich, Youngwook Ahn, Yotam Ashkenazi, Anthony Carlo, Matthew A. Cerny, Karen J. Coffman, Jeffrey A. Culver, Anne-Marie Dechert Schmitt, Heather Eng, Ethan L. Fisher, Jemy A. Gutierrez, Larry James, Samantha Jordan, Jeffrey T. Kohrt, Melissa Kramer, Erik A. LaChapelle, Jack C. Lee, Jisun Lee, Dongmei Li, Zhenhong Li, Shenping Liu, Jianhua Liu, Thomas V. Magee, Melissa R. Miller, Michael Moran, Deane M. Nason, Nicole L. Nedoma, Steven V. O’Neil, Mary A. Piotrowski, Jillian Racich, Ruth F. Sommese, Lucy M. Stevens, Ann S. Wright, Jun Xiao, Liying Zhang, Dahui Zhou, Ornella Barrandon, Michelle F. Clasquin

“…Their application to cells endogenously expressing 17B-HSD13 enables quantitative measures of enzymatic inhibition in primary human hepatocytes which has never been reported to date. …”
Get full text

Adult Hippocampal Neurogenesis in Alzheimer’s Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory Recovery by Stefano Farioli-Vecchioli, Valentina Ricci, Silvia Middei

“…Here, we review the literature on adult hippocampal neurogenesis (AHN) and AD by focusing on both human and mouse model studies. First, we describe key steps of AHN, report recent evidence of this phenomenon in humans, and describe the specific contribution of newborn neurons to memory, as evinced by animal studies. …”
Get full text

Development and Optimization of a Multiplex Real-Time RT-PCR to Detect SARS-CoV-2 in Human Samples by Camilo Castellar-Mendoza, María-Angélica Calderón-Peláez, Jaime E. Castellanos, Myriam L. Velandia-Romero, Carolina Coronel-Ruiz, Sigrid Camacho-Ortega, Lilia J. Bernal-Cepeda, Lady López-Ibarra, Jhann A. Arturo, Félix G. Delgado, Hernando Gutierrez-Barbosa, Sonia Bohorquez-Avila, Johanna Madroñero, Zayda L. Corredor-Rozo, Sandra J. Perdomo-Lara, Angela Fonseca-Benitez, Eliana Calvo

Get full text

Large language model usage guidelines in Korean medical journals: a survey using human-artificial intelligence collaboration by Sangzin Ahn

“…Author guidelines were collected and screened by a human researcher and AI chatbot to identify AI-related content. …”
Get full text

Correlation between Clinicopathology and Expression of Heat Shock Protein 72 and Glycoprotein 96 in Human Esophageal Squamous Cell Carcinoma by Xiaoping Wang, Qiaoxia Wang, Huanping Lin

“…We investigated the correlation between clinicopathology and expression of HSP72 and gp96 in human esophageal squamous cell carcinoma. The expression of HSP72 and gp96 was studied in 120 human esophageal squamous cell carcinomas with or without metastasis as well as in mucous membrane adjacent to cancers by way of immunohistochemistry. …”
Get full text

β-synuclein in cerebrospinal fluid as a potential biomarker for distinguishing human prion diseases from Alzheimer’s and Parkinson’s disease by Bing Xu, Kang Xiao, Xiaoxi Jia, Rundong Cao, Donglin Liang, Ruhan A, Weiwei Zhang, Chunjie Li, Liping Gao, Cao Chen, Qi Shi, Xiaoping Dong

Subjects: Get full text

Communication invitée du thèmeLes corps maladesWhy are health and sickness socially patterned across human societies? by Michelle Kelly-Irving

Get full text

Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings by Rushika Conroy, Gerardo Febres, Donald J. McMahon, Michael O. Thorner, Bruce D. Gaylinn, Irene Conwell, Louis Aronne, Judith Korner

“…Weight stable women after RYGB were randomized to receive placebo or recombinant human metreleptin (0.05 mg/kg twice daily). At weeks 0 and 16, a liquid meal challenge was performed. …”
Get full text

Transgression de l’espace et espace de la transgression dans The Human Stain de Philip Roth by Gilles Mayné

“…He is then disavowed and banned from the university community. Reading The Human Stain, one is forced to question what is generally considered as being evil and to become aware of the extreme difficulty and yet unavoidable necessity to transgress the space of the supposed common good which locks the notions up within themselves to freeze conscious thinking and behavior.…”
Get full text

CHARACTERISTIC CHANGES IN THE COPY NUMBER OF INTERSPERSED REPEATS IN BONE MARROW CELLS OF MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS HUMAN DNA by E. V. Dolgova, A. V. Prokopenko, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. V. Panov, S. N. Zagrebelnyi, M. A. Shurdov

Get full text

Writing and Its Place in Human Cultural and Cognitive Evolution; A Review of The book "The Formation and Development of Proto-Writing in Iran” by Vahid Askarpour

“…The book is interesting which makes it one of the fundamental breakthroughs of human cultures and humanity, namely how the formation of writing systems as well as their archaeological origins. …”
Get full text

Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix by Xiaodong Feng, Marcia G. Tonnesen, Shaker A. Mousa, Richard A. F. Clark

Get full text