Comparison of Two Methodologies for CD4+ T Lymphocytes Relative Counting on Immune Monitoring of Patients with Human Immunodeficiency Virus by Danielle Cristyane Kalva Borato, Emerson Carraro, Sônia Regina Weber Ribas, Carlos Augusto Kalva-Filho, José Carlos Rebuglio Vellosa

Get full text

Combined Effects of PPARγ Agonists and Epidermal Growth Factor Receptor Inhibitors in Human Proximal Tubule Cells by Katherine Pegg, Jie Zhang, Carol Pollock, Sonia Saad

“…We aimed to determine whether epidermal growth factor receptor (EGFR) inhibition, in addition to a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, prevents high-glucose-induced proximal tubular fibrosis, inflammation, and sodium and water retention in human proximal tubule cells exposed to normal glucose; high glucose; high glucose with the PPARγ agonist pioglitazone or with the P-EGFR inhibitor, gefitinib; or high glucose with both pioglitazone and gefitinib. …”
Get full text

Immunohistochemical Profile of p62/SQSTM1/Sequestosome-1 in Human Low- and High-Grade Intracranial Meningiomas by Antonio Ieni, Cristina Pizzimenti, Vincenzo Fiorentino, Mariausilia Franchina, Antonino Germanò, Giovanni Raffa, Maurizio Martini, Guido Fadda, Giovanni Tuccari

Get full text

The Cryo-EM structure of human CD163 bound to haptoglobin-hemoglobin reveals molecular mechanisms of hemoglobin scavenging by Anders Etzerodt, Jakob Hauge Mikkelsen, Morten Torvund-Jensen, Dorle Hennig, Thomas Boesen, Jonas Heilskov Graversen, Søren Kragh Moestrup, Justin M. Kollman, Christian Brix Folsted Andersen

“…Here, we present the cryo-electron microscopy structure of the entire extracellular domain of human CD163 in complex with haptoglobin-hemoglobin. …”
Get full text

Book review: Paus, Tomáš and Kum, Hye-Chung (eds.). Digital ethology: human behavior in geospatial context by Elena Maceviciute

“… Paus, Tomáš and Kum, Hye-Chung (eds.). (2024). Digital ethology: human behavior in geospatial context. Cambridge, Mas.: MIT Press. x, 279 p. …”
Get full text

The Active Compound Thymoquinone Alters Chondrogenic Differentiation of Human Mesenchymal Stem Cells via Modulation of Intracellular Signaling by Banu ISKENDER

Subjects: “…human mesenchymal stem cells…”
Get full text

Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells by Yeri Alice Rim, Yoojun Nam, Narae Park, Hyerin Jung, Yeonsue Jang, Jennifer Lee, Ji Hyeon Ju

“…Scientists have tried to reprogram various origins of primary cells into human induced pluripotent stem cells (hiPSCs). Every somatic cell can theoretically become a hiPSC and give rise to targeted cells of the human body. …”
Get full text

A novel approach to completely alleviate peripheral neuropathic pain in human patients: insights from preclinical data by Safa Shehab, Mohammad I. K. Hamad, Bright Starling Emerald

“…In an animal model of neuropathic pain where the fifth lumbar (L5) spinal nerve is unilaterally ligated and cut, resulting in ipsilateral hyperalgesia, allodynia, and spontaneous pain akin to human neuropathic pain. The application of capsaicin or RTX to the adjacent uninjured L3 and L4 nerves completely alleviated and prevented mechanical and thermal hyperalgesia following the L5 nerve injury. …”
Get full text

Predicting the Spatial-Temporal Distribution of Human Brucellosis in Europe Based on Convolutional Long Short-Term Memory Network by Li Shen, Chenghao Jiang, Minghao Sun, Xuan Qiu, Jiaqi Qian, Shuxuan Song, Qingwu Hu, Heilili Yelixiati, Kun Liu

“…Brucellosis is a chronic infectious disease caused by brucellae or other bacteria directly invading human body. Brucellosis presents the aggregation characteristics and periodic law of infectious diseases in temporal and spatial distribution. …”
Get full text

Oncogenic human papillomavirus and anal microbiota in men who have sex with men and are living with HIV in Northern Taiwan. by Shu-Hsing Cheng, Yu-Chen Yang, Cheng-Pin Chen, Hui-Ting Hsieh, Yi-Chun Lin, Chien-Yu Cheng, Kuo-Sheng Liao, Fang-Yeh Chu, Yun-Ru Liu

“…Few studies have demonstrated the interplay between human immunodeficiency virus (HIV), anal human papillomavirus (HPV), and anal microbiota, especially in persons living with HIV who are men who have sex with men. …”
Get full text

The Viral Load of Human Cytomegalovirus Infection in Children following Hematopoietic Stem Cell Transplant by Chip Digital PCR by Wen-Jun Wang, Miao Feng, Feng He, Juan Song, Qin-Qin Song, Dong Xia, Rong Liu, Hai-Lan Yao, Jun Han

“…To detect viral load in human cytomegalovirus (HCMV) infection children after hematopoietic stem cell transplant (HSCT) by chip digital PCR (cdPCR). …”
Get full text

Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton’s Jelly, Bone Marrow, and Pancreatic Tissues by Shih-Yi Kao, Jia-Fwu Shyu, Hwai-Shi Wang, Chi-Hung Lin, Cheng-Hsi Su, Tien-Hua Chen, Zen-Chung Weng, Pei-Jiun Tsai

“…Insulin-producing cells (IPCs) differentiated from mesenchymal stem cells (MSCs) in human tissues decrease blood glucose levels and improve survival in diabetic rats. …”
Get full text

Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord by Yali Chen, Yiyong Wei, Jin Liu, Tao Zhu, Cheng Zhou, Donghang Zhang

Subjects: Get full text

Interferon-based agents for current and future viral respiratory infections: A scoping literature review of human studies. by Aldina Mesic, Emahlea K Jackson, Mathias Lalika, David M Koelle, Rena C Patel

“…Here we review the comparative efficacy, safety/tolerability, and future potential of IFN-based therapeutics. We reviewed human studies in which IFN or IFN pathway-interacting agents were used for viral respiratory infections. …”
Get full text

A study on the production of extracellular vesicles derived from novel immortalized human placental mesenchymal stromal cells by Yingying Tong, Jie Sun, Xin Jiang, Xu Jia, Huimin Xiao, Hua Wang, Guanghua Yang

“…In our study, we propose a method for efficiently harvesting EVs utilizing simian virus 40 large T antigen (SV40LT) immortalized human placental chorionic mesenchymal stromal cells (CMSCs). …”
Get full text

Effect of Human Bone Marrow Mesenchymal Stem Cells on Burn Healing in Granulation Tissue Formation in Diabetic Rats by Gusti Revilla, Deddy Saputra, Dini Nurhasanah

“…Keywords: burn wound,  diabetic rat, human bone marrow mesenchymal stem cells, granulation tissue…”
Get full text

Validated HPLC Methodology for Pregabalin Quantification in Human Urine Using 1-Fluoro-2,4-dinitrobenzene Derivatization by Mohamedsaid mostafa Said Mostafa, Hosam Abdel Fattah Mohamed Elshebiny, Olfat Elsayed Mostafa, Shimaa Talaat Elsayed, Mohamed Abdelizm Abdelaziz

“…This study aimed to validate a simple, sensitive, and accurate method for PGB quantification in human urine using the HPLC technique with 1-Fluoro-2, 4-dinitrobenzene used as a derivatizing agent. …”
Get full text

A Radar-Based System for Detection of Human Fall Utilizing Analog Hardware Architectures of Decision Tree Model by Vassilis Alimisis, Dimitrios G. Arnaoutoglou, Emmanouil Anastasios Serlis, Argyro Kamperi, Konstantinos Metaxas, George A. Kyriacou, Paul P. Sotiriadis

Get full text

Lowering Caveolin-1 Expression in Human Vascular Endothelial Cells Inhibits Signal Transduction in Response to Shear Stress by A. D. van der Meer, M. M. J. Kamphuis, A. A. Poot, J. Feijen, I. Vermes

“…In this study, caveolin-1 was downregulated in human endothelial cells by RNAi. When these cells were subjected to a shear stress of 15 dyn/cm2 for 10 minutes, activation of Akt and ERK1/2 was significantly lower than in control cells. …”
Get full text

Sustainable digital leap: a bibliometric study on its impact on human learning and organizational development in the MENA region by Ajay Singh

Subjects: Get full text