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32261
Evaluating the impact of donor eGFR and HLA-DR mismatch on graft survival in living donor kidney transplants
Published 2025-01-01“…BackgroundThis study assesses the impact of human leukocyte antigen (HLA)-DR mismatch and donor-estimated glomerular filtration rate (eGFR) on outcomes of living donor kidney transplantation (LDKT), which are especially relevant to the availability of multiple donors and paired kidney exchanges.MethodsUsing data from the Scientific Registry of Transplant Recipients (SRTR), we retrospectively analyzed graft survival in adult LDKT recipients transplanted between January 2013 and September 2022. …”
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32262
Golden Eagle in Karatau and Chu-Ili Mountains (Kazakhstan) and Assessment of Risks to its Populations from Developing Wind Energy
Published 2025-01-01“…The results of this study apply to the conservation planning efforts of the Golden Eagle, analysing the risks of developing not only wind energy but also other land uses, including mining and even recreation, and implementing compensatory measures for human intervention in the Goolden Eagle's habitat.…”
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32263
Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons
Published 2025-03-01“…Avian influenza viruses (AIVs) are potential pandemic of global concern, posing a major threat to both the poultry industry and human health. Host factors play a key role in the replication of AIVs, while the function of complement component 4 binding protein, membrane (C4BPM) in this process is still unclear. …”
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32264
Assessing cell lines with inducible depletion of cohesin and condensins components through analysis of metaphase chromosome morphology
Published 2024-04-01“…In this work, we obtained a series of clones of human HAP1 cells carrying the necessary genetic constructs for inducible depletion of RAD21 and SMC2. …”
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32265
Effects of Functional Red Pine Seed Direct-Drinking Oil on Constipation and Intestinal Barrier Function in Mice
Published 2024-12-01“…Constipation is a prevalent global health issue that greatly affects human well-being. However, many existing treatments are associated with side effects, necessitating the development of alternative approaches. …”
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32266
Ultrasonic-assisted adsorption of methylene blue using shrimp shells as a low-cost adsorbent: Evaluation on the adsorption isotherm, kinetics, and thermodynamics
Published 2025-04-01“…However, its presence in wastewater negatively affects the environment, human health, and aquatic life. Adsorption is recognized as an effective and economical method for removing methylene blue from wastewater. …”
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32267
A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
Published 2024-11-01“…Resistance of mosquitoes to insecticides is one example of rapid adaptation to anthropogenic selection pressures having a strong impact on human health and activities. Target-site modification and increased insecticide detoxification are the two main mechanisms underlying insecticide resistance in mosquitoes. …”
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32268
Regulatory factor X‐5/SCL/TAL1 interruption site axis promotes aerobic glycolysis and hepatocellular carcinoma cell stemness
Published 2025-01-01“…Although research has revealed how important SCL/TAL1 interruption site (STIL) is in many human tumors, the impact of STIL on HCC stem cells is poorly understood. …”
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32269
“Equity” in genomic health policies: a review of policies in the international arena
Published 2024-12-01“…In addition, General and Specific Policy Repositories, Global Consortia in Genomic Medicine, WHO Collaborating Centers in Genomics, Australian Genomics, Public Policy Projects, Global Genomic Medicine Consortium (G2MC), G2MC conference Oct 2023 and National Human Genome Research Institute databases were searched using the inclusion and exclusion criteria. …”
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32270
Iterative delivery of an implementation support package to increase and sustain the routine provision of antenatal care addressing alcohol consumption during pregnancy: study proto...
Published 2022-07-01“…Economic and process evaluation measures will also be reported.Ethics and dissemination Ethical approval was obtained through the Hunter New England (16/11/16/4.07, 16/10/19/5.15) and University of Newcastle Human Research Ethics Committees (H-2017-0032, H-2016-0422) and the Aboriginal Health and Medical Research Council (1236/16). …”
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32271
Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure
Published 2025-02-01“…Background PDE2 (phosphodiesterase 2) is upregulated in human heart failure. Cardiac PDE2‐transgenic mice are protected against contractile dysfunction and arrhythmias in heart failure but whether an acute elevation of PDE2 could be of therapeutic value remains elusive. …”
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32272
Clinical and ultrasound assessment of body composition in preterm infants at discharge: an observational study
Published 2025-01-01“…Higher nutritional support during the first 2 weeks of life was related to a lower loss of length z-scores, and exclusive human milk feeding correlates with arm fat-to-circumference ratio.Conclusions Growth and BC of VPIs can be approached using simpler measures in clinical practice. …”
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32273
Brodalumab: Six-Year US Pharmacovigilance Report
Published 2024-11-01“…Abstract Introduction Brodalumab is a human interleukin-17 receptor A antagonist indicated for the treatment of moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy and have failed to respond or have lost response to other systemic therapies. …”
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32274
Preliminary Exploration of Natural Polyphenols and/or Herbal Mix Replacing Sodium Nitrate to Improve the Storage Quality of Pork Sausage
Published 2025-01-01“…However, these compounds can be harmful to human health, due to their carcinogenic potential. …”
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32275
Association between mixed exposure of non-persistent pesticides and liver fibrosis in the general US population: NHANES 2013–2016
Published 2025-01-01“…This study indicates that exposure to non-persistent pesticides mixture is associated with increased risk of liver fibrosis in humans, and provide new insight into the hepatotoxic potential of non-persistent pesticides.…”
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32276
Implications of the Improvement in Atmospheric Fine Particles: A Case Study of COVID-19 Pandemic in Northern Taiwan
Published 2023-03-01“…This study investigated the variations in sources, chemical characteristics and human health risks of PM2.5 comprehensively. The PM2.5 mass concentrations decreased from pre-alert to Level 3 alert by 49.4%, and the inorganic ions, i.e., NH4+, NO3− and SO42−, dropped even more by 71%, 90% and 52%, respectively. …”
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32277
Parental conflicts and resource sharing: Evolutionary trade-off
Published 2025-02-01“…This interaction has molded the strategies and behaviors that affect resource distribution within families, applicable to both humans and other species.…”
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32278
Self-Assembled Peptide Hydrogels PPI45 and PPI47: Novel Drug Candidates for <i>Staphylococcus aureus</i> Infection Treatment
Published 2025-01-01“…In vitro safety assessments indicated minimal hemolytic activity on murine red blood cells and low cytotoxicity on human immortalized epidermal cells (HaCaT). In summary, this work lays a valuable cornerstone for the future design and characterization of self-assembling antimicrobial peptides hydrogels to combat <i>S. aureus</i> infection.…”
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32279
Brief exposure to (-) THC affects zebrafish embryonic locomotion with effects that persist into the next generation
Published 2025-01-01“…Abstract Cannabis is one of the most widely used drugs, and yet an understanding of its impact on the human brain and body is inconclusive. Medicinal and recreational use of cannabis has increased in the last decade with a concomitant increase in use by pregnant women. …”
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32280
Comparing the Critical Thinking Skills of Dentistry, Engineering, and Law Students: A Cross-Sectional Study in Mashhad, Iran
Published 2024-11-01“…This problem shows that certain educational practices need to be reviewed, and more attention should be paid to training human and conceptual skills as part of education planning.…”
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