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32141
Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives
Published 2025-02-01“…Targeted therapies against key targets in GC, including epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR), have shown remarkable therapeutic efficacies by inhibiting tumor progression and/or blood supply. …”
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32142
Evaluation of mucosal adjuvants to chitosan-nanoparticle-based oral subunit vaccine for controlling salmonellosis in broilers
Published 2025-02-01“…Poultry meat and eggs are recognized as the major source of Salmonella food poisoning in humans. Our study evaluated the protective efficacy of mannose-conjugated chitosan-nanoparticle (mChitosan-NP)-based subunit vaccine, consisting of immunogenic outer membrane proteins and flagella of Salmonella Enteritidis [mChitosan (OMP+FLA)/FLA-NP], coadministered orally with potent mucosal adjuvants to reduce the colonization of S. …”
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32143
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32144
A prospective model of the potential clinical and economic impact of cervical cancer screening supported by a mobile phone app.
Published 2025-01-01“…Implementing World Health Organization screening guidelines for human papillomavirus (HPV) is challenging due to the complex logistics of result return and follow-up requiring multiple clinic visits. …”
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32145
Isolation and Antifungal Susceptibility of Candida spp. from Pediatric Patients in Kurdistan of Iraq
Published 2023-06-01“…Candida species are considered the most common opportunistic human fungal pathogen due to the presence of various virulence factors, including its ability to form a biofilm that aids in oral candidiasis. …”
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32146
Antiviral Drugs and Vaccines for Omicron Variant: A Focused Review
Published 2023-01-01“…For future advances, the ribosome display technology can be applied for the generation of human single-chain fragment variable (scFv) antibodies from B cells of recovered patients against Omicron and other Coronavirus variants as they are easier and faster to produce and have high affinity and high specificity.…”
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32147
Perceived costs and benefits of companion dog keeping based on a convenience sample of dog owners
Published 2025-01-01“…Abstract The increasing trend of dog ownership is often linked to its perceived benefits for human physical and mental well-being. However, the psychological and practical demands of caring for a dog can significantly impact the owner’s quality of life and the long-term success of the dog-owner relationship. …”
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32148
Clinical Holistic Medicine: A Pilot Study on HIV and Quality of Life and a Suggested Cure for HIV and AIDS
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32149
Reactivation of mTOR signaling slows neurodegeneration in a lysosomal sphingolipid storage disease
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32150
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32151
Annotated review of the mammal fauna in the Chornobyl Biosphere Reserve as of 2023
Published 2024-12-01“…The abundance of most species shows significant long-term and seasonal fluctuations, influenced by climate change, disease, shifts in vegetation, wildfires, floods, intraspecies dynamics, and occasionally human activity. Certain species (lynx, Przewalski’s horse, and bear) continue to increase in number, while the red deer has shifted from being a non-abundant to a dominant species. …”
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32152
Recent global patterns in skin cancer incidence, mortality, and prevalence
Published 2025-01-01“…In addition, correlations between Human Development Index (HDI) and age-standardized incidence and mortality rates of these two skin cancers are described. …”
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32153
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32154
Serotype distribution and antimicrobial susceptibility of Streptococcus suis isolates from porcine diagnostic samples in Hungary, 2020–2023
Published 2025-01-01“…Antimicrobial susceptibility testing of the isolates was performed by determining the minimal inhibitory concentration for 15 antimicrobial agents of veterinary and human importance using a commercial microdilution assay. …”
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32155
Prevalence of HPV in a Peruvian Healthcare Network: A Descriptive Cross-Sectional Study
Published 2025-01-01“…Introduction Human papillomavirus (HPV) infection is a common sexually transmitted infection often associated with cancer development. …”
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32156
The neuroendocrine stress-response in insects: the history of the development of the concept
Published 2017-12-01“…The study of stress reaction in insects has both theoretical importance, as it demonstrates the convergence of evolutionary pathways of adaptive transformations in such distant taxa as insects and mammals, and practical importance, since the patterns of this reaction’s mechanisms can be used in modeling hereditary or acquired human diseases, in developing breeding methods for economically valuable insects and in finding ways to fight insect pests…”
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32157
Significance of immune factors in Crohn's disease development
Published 2015-07-01“…Series of the population studies, confirming association of HLA antigens with human diseases were carried out. Main histocompatibility complex (MHC) plays the leading role in immune response as well as in development of CD, therefore occurrence of disease is related to changes at genetic level. …”
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32158
Changes in the Parietal Lobe Subregion Volume at Various Stages of Alzheimer’s Disease and the Role in Cognitively Normal and Mild Cognitive Impairment Conversion
Published 2025-01-01“…We measured the volume of the parietal subregion based on the Human Brainnetome Atlas (BNA-246) using voxel-based morphometry among individuals at various stages of AD and the progressive and stable individuals in CN and MCI. …”
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32159
INTENSITY OF OXIDATIVE STRESS DEVELOPMENT IN RAT MAJOR CEREBRAL HEMISPHERES UNDER COMBINED CONDITIONS OF SYSTEMIC INFLAMMATORY RESPONSE, CHANGES IN THE NORMAL LIGHT-DARK CYCLE, AN...
Published 2024-07-01“…The effects of antidepressants on the human body are also actively studied. The aim of this study was to investigate the effect of fluoxetine on oxidative stress in the rat cerebral hemispheres under conditions of acute desynchronosis (AD), systemic inflammatory response (SIR), and fluoxetine administration. …”
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32160