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  1. 3181
  2. 3182

    Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells by Jonathan Kevin Sia, Maria Georgieva, Jyothi Rengarajan

    Published 2015-01-01
    “…Tuberculosis (TB) remains a serious global public health problem that results in up to 2 million deaths each year. TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung. …”
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  3. 3183

    Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells by Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki

    Published 2021-01-01
    “…In this study, we aimed to examine the anti-inflammatory effects of nobiletin on tumor necrosis factor- (TNF-) stimulated human periodontal ligament cells (HPDLCs). Our results demonstrated that nobiletin treatment could decrease the expressions of inflammatory cytokines (C-X-C motif chemokine ligand (CXCL)10, C-C motif chemokine ligand (CCL)2, and interleukin- (IL-) 8), matrix metalloproteinases (MMPs) (MMP1 and MMP3), and prostaglandin-endoperoxide synthase 2 (PTGS2) in TNF-stimulated HPDLCs. …”
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  4. 3184

    Critical linkages between land use change and human health in the Amazon region: A scoping review. by Molly Mastel, Alejandra Bussalleu, Valerie A Paz-Soldán, Gabriela Salmón-Mulanovich, Armando Valdés-Velásquez, Stella M Hartinger

    Published 2018-01-01
    “…Our research aims to examine the current state of evidence on the link between LUC and human health in the Amazon region. We conducted a scoping review of literature in two research databases, resulting in 14 papers for analysis. …”
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  7. 3187

    VEGF Promotes Proliferation of Human Glioblastoma Multiforme Stem-Like Cells through VEGF Receptor 2 by Chengshi Xu, Xing Wu, Jianhong Zhu

    Published 2013-01-01
    “…In this study, human GBSCs were isolated from surgical specimens of glioblastoma and cultured in medium favored for stem cell growth. …”
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  8. 3188

    Analysis of Drug Effects on Primary Human Coronary Artery Endothelial Cells Activated by Serum Amyloid A by K. Lakota, D. Hrušovar, M. Ogrič, K. Mrak-Poljšak, S. Čučnik, M. Tomšič, B. Božič, P. Žigon, S. Sodin-Semrl

    Published 2018-01-01
    “…To determine the effects of medications on SAA-stimulated human coronary artery endothelial cells (HCAEC). …”
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  9. 3189

    Tackling antimicrobial resistance in Bangladesh: A scoping review of policy and practice in human, animal and environment sectors. by Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam, Emily K Rousham, Bushra Zarin Islam, Shaikh Hassan

    Published 2020-01-01
    “…We used Google Scholar, Pubmed, and Biomed Central databases for searching peer-reviewed literature in human, animal and environment sectors during January 2010-August 2019, and Google for grey materials from the institutional and journal websites. …”
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  10. 3190

    New discoveries of Middle Paleolithic human remains from the “Bau de l'Aubésier (Vaucluse, France)” by Serge Lebel, Erik Trinkaus

    Published 2001-06-01
    “…The Middle Pleistocene remains (Aubesier 10 and 11) have close morphological affinities to contemporaneous European human remains, and the Neandertal molar (Aubesier 12) falls well within Neandertal ranges of variation. …”
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  11. 3191

    Assessment of Human-originated Medroxyprogesterone Acetate (MPA) as Effective Contraceptive in Domesticated Queens (Felis catus) in Iraq by Mushtaq A Alabodi, Imad M Almeeni

    Published 2024-12-01
    “…This study investigated the use of medroxyprogesterone acetate (MPA), precisely the human formulation Depo-Provera®, as a potential solution for feline contraception. …”
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  12. 3192

    Heavy chain-only antibodies with a stabilized human VH in transgenic chickens for therapeutic antibody discovery by Christine N. Vuong, Kevin M. Reynolds, Gerry S. Rivera, Baisen Zeng, Zahra Karimpourkalou, Manith Norng, Yulei Zhang, Robayet Chowdhury, Darlene Pedersen, Melissa Pantoja, Ellen Collarini, Swetha Garimalla, Shelley Izquierdo, Eric G. Vajda, Brett Antonio, Devendra B. Srivastava, Marie-Cecile van de Lavoir, Yasmina Abdiche, William Harriman, Philip A. Leighton

    Published 2024-12-01
    “…We have developed transgenic chickens expressing heavy chain-only antibodies with a human variable region to combine the superior target recognition advantages of a divergent, non-mammalian host with the ability to discover single-domain binders. …”
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  13. 3193

    Perancangan Pengalaman Pengguna Portal Job Fair Sarjana Sakti dengan Pendekatan Human-Centered Design by Annisah Amalia, Herman Tolle, Ratih Kartika Dewi

    Published 2022-12-01
    “…Aplikasi ini dirancang dengan menggunakan pendekatan Human-Centered Design (HCD) karena memiliki strategi desain yang iterative untuk mendapatkan hasil yang diharapkan. …”
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  14. 3194

    Sensitivity analysis of a mathematical model for malaria transmission accounting for infected ignorant humans and relapse dynamics by Getahun Tadesse Haile, Purnachandra Rao Koya, Fekadu Mosisa Legesse

    Published 2025-01-01
    “…This article presents and analyzes a deterministic model for malaria transmission that incorporates infected individuals who are unaware of their infectious status (ignorant infected humans) and accounts for relapse dynamics. We explore the invariant region and positivity of the model and calculate the effective reproduction number using the next-generation matrix method. …”
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  15. 3195

    Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes by Ehsan Zamani, Alireza Ahmadi Shad, Hediye Fatemi, Saba Mahboubi, Azadeh Motavallian, Mehdi Evazalipour

    Published 2022-01-01
    “…Therefore, using carvacrol as a natural antioxidant protected human lymphocytes against haloperidol genetic damage.…”
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  16. 3196

    TNF-α Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B by Letizia Mezzasoma, Lucio Cagini, Cinzia Antognelli, Francesco Puma, Eugenio Pacifico, Vincenzo Nicola Talesa

    Published 2013-01-01
    “…Here, we showed that TNF-α selectively regulates key molecules involved in fluids balance, such as natriuretic peptides (NPs) and aquaporins, in human bronchial epithelial cells BEAS-2B. In particular, we found that TNF-α induced a decrease of arial natriuretic peptide, natriuretic peptide receptor-1, aquaporin-1 and aquaporin-5 and an increase of brain natriuretic peptide with a different involvement of nuclear factor-κB and mitogen-activated protein kinases signaling pathway activation. …”
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  17. 3197

    Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics by Xi Yang, Xuemin Chen, Wei Yang, Yves Pommier

    Published 2025-01-01
    “…We present a series of cryo-EM structures of human TOP3B with its cofactor TDRD3 during cleavage and rejoining of DNA or RNA, thus elucidating the roles of divalent metal ions and key enzyme residues in each step of the catalytic cycle. …”
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  18. 3198

    Phospholipase A2 Mediates Apolipoprotein-Independent Uptake of Chylomicron Remnant-Like Particles by Human Macrophages by Mariarosaria Napolitano, Howard S. Kruth, Elena Bravo

    Published 2012-01-01
    “…To investigate these mechanisms, triacylglycerol (TG) accumulation induced by apolipoprotein-free chylomicron remnant-like particles (CRLPw/o) in human monocyte-derived macrophages was evaluated. …”
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  19. 3199

    Silk of the Indian meal moth Plodia interpunctella (Hübner, 1813) affects the human colon cancer cells by Nikodijević Danijela, Milutinović Milena, Radenković Nikola, Blagojević Stefan, Vasiljević Anđela, Jurišić Vladimir, Predojević Dragana, Vukajlović Filip, Pešić Snežana

    Published 2024-01-01
    “…The selective effect of silk indicates the presence of a high level of biocompatibility with normal human cells. Based on the results of increased gene expression for caspase 8 and 9 in silk extract-treated cells compared to control, apoptosis was induced by a caspase-dependent pathway.…”
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  20. 3200

    Silent Human Trypanosoma brucei gambiense Infections around the Old Gboko Sleeping Sickness Focus in Nigeria by Karshima Solomon Ngutor, Lawal A. Idris, Okubanjo Oluseyi Oluyinka

    Published 2016-01-01
    “…Trypanosoma brucei gambiense causes Gambian trypanosomosis, a disease ravaging affected rural parts of Sub-Saharan Africa. We screened 1200 human blood samples for T. b. gambiense using the card agglutination test for trypanosomosis, characterized trypanosome isolates with Trypanosoma gambiense serum glycoprotein-PCR (TgsGP-PCR), and analyzed our data using Chi square and odds ratio at 95% confidence interval for statistical association. …”
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