Identifying Candidate Genes for Type 2 Diabetes Mellitus and Obesity through Gene Expression Profiling in Multiple Tissues or Cells by Junhui Chen, Yuhuan Meng, Jinghui Zhou, Min Zhuo, Fei Ling, Yu Zhang, Hongli Du, Xiaoning Wang

“…In the current study, gene expression levels in multiple human tissues from GEO datasets were analyzed, and 21 candidate genes displaying high percentages of differential expression were filtered out. …”
Get full text

Understanding the role of the gut microbiome in solid tumor responses to immune checkpoint inhibitors for personalized therapeutic strategies: a review by Mi Young Lim, Seungpyo Hong, Young-Do Nam

“…In this review, we discuss key findings from human observational studies assessing the effect of antibiotic use prior to ICI therapy on outcomes and identifying specific gut bacteria associated with favorable and unfavorable responses. …”
Get full text

Adsorption of Cd (II) Using Chemically Modified Rice Husk: Characterization, Equilibrium, and Kinetic Studies by Javier Montalvo-Andía, Warren Reátegui-Romero, Alexis D. Peña-Contreras, Walter F. Zaldivar Alvarez, María E. King-Santos, Víctor Fernández-Guzmán, José Luis Guerrero-Guevara, Jhon E. Puris-Naupay

“…Cadmium (Cd) is a highly toxic heavy metal considered carcinogenic to humans. The adsorption behavior of cadmium adsorption using untreated and chemically modified rice husk was investigated. …”
Get full text

Anti-cancer effect of midazolam via downregulating YWHAH in papillary thyroid cancer cells by Yang Li, Ai-Ping Tan, Yu-Shan Zhong

“…Cell viability was detected by CCK-8 method when treated by varying doses of midazolam to detect the cytotoxicity of midazolam on human thyroid follicular epithelial cell line and thyroid cancer cell lines. …”
Get full text

Synthesis and characterization of Fe2O3 nanoparticles reinforced to recycled industrial aluminium scrap and waste aluminium beverage cans for preparing metal matrix nanocomposites by Ganesh R. Chate, Raviraj M. Kulkarni, Manjunath Patel G. C., Avinash Lakshmikanthan, Harsha H. M., Simran Tophakhane, Nazafali Shaikh, Suman Kongi, Pouravi Iranavar

“…Increased material demand in all sectors is primarily due to exponential growth in population to fulfill human needs and comforts. Recycling of collected aluminium beverage cans and Al 6061 alloy scraps from industries ensures significant advantages in terms of energy savings with reduced environmental problems in fabricating composite parts economically. …”
Get full text

Perspectives in Molecular Imaging Using Staging Biomarkers and Immunotherapies in Alzheimer’s Disease by Benoît Leclerc, Abedelnasser Abulrob

“…The complex molecular mechanisms of AD not only are supported by cholinergic, beta-amyloid, and tau theories but also have a genetic basis that accounts for the difference in symptomatology processes activation among human population which will evolve into divergent neuropathological features underlying cognitive and behaviour alterations. …”
Get full text

Land Subsidence in the Yangtze River Delta, China Explored Using InSAR Technique From 2019 to 2021 by Hongbo Jiang, Guangcai Feng, Yuexin Wang, Zhiqiang Xiong, Hesheng Chen, Ning Li, Zeng Lin

“…The combined effects of global warming and human activities have intensified land subsidence (LS), limiting the sustainable development of economy in delta regions. …”
Get full text

Adenocarcinoma with Neuroendocrine Differentiation of the Colon Accompanying Osteoclast-Like Giant Cells by Mitsuhiro Tachibana, Tadahiro Isono, Yutaka Tsutsumi

“…The carcinoma cells were labeled focally for synaptophysin and diffusely for the DR locus of the human leukocyte antigen and programmed death-ligand 1 (PD-L1). …”
Get full text

Government crisis communication tools in the light of the extreme drought of 2022 by Ágnes Kovács, Edina Kriskó, Tamás Pálvölgyi, László Balatonyi

“…Value: Due to the acceleration of the hydrological cycle, it is likely that in the future humanity will have to prepare for more intense periods of extreme water scarcity. …”
Get full text

Transcutaneous Intraluminal Impedance Measurement for Minimally Invasive Monitoring of Gastric Motility: Validation in Acute Canine Models by Michael D. Poscente, Gang Wang, Dobromir Filip, Polya Ninova, Gregory Muench, Orly Yadid-Pecht, Martin P. Mintchev, Christopher N. Andrews

“…Further chronic animal studies of this novel long-term gastric motility measurement technique are needed before testing it on humans.…”
Get full text

Cell-Type-Specific Differentiation and Molecular Profiles in Skin Transplantation: Implication of Medical Approach for Genetic Skin Diseases by Noritaka Oyama, Fumio Kaneko

“…These local events are more unlikely to be regulated by the host immunity, because human skin transplantation has accomplished the donor skin engraftment onto the immunocompromised or immunosuppressive animals. …”
Get full text

Seroprevalence of Toxoplasma gondii in Women Who Have Aborted in Comparison with the Women with Normal Delivery in Ahvaz, Southwest of Iran by J. Saki, N. Mohammadpour, F. Moramezi, S. Khademvatan

“…Toxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. …”
Get full text

Can floseal™ be applied safely during otologic surgery? Assessment of ototoxicity in a chinchilla animal model by Carol Nhan, Aren Bezdjian, Abdullah Alarfaj, Sam J. Daniel

“…More studies are warranted to assess the safety and applicability of the product in humans.…”
Get full text

Developmental Changes in Sleep Oscillations during Early Childhood by Eckehard Olbrich, Thomas Rusterholz, Monique K. LeBourgeois, Peter Achermann

“…This study utilized our time-frequency method to examine sleep oscillations as characteristic features of human sleep EEG. Data were collected from a longitudinal sample of young children (n=8; 3 males) at ages 2, 3, and 5 years. …”
Get full text

Banana residue could be a viable rice straw alternative for Pleurotus mushroom production by Hend Hamed, Mohamed Mohamed, Khalid elshaikh, Maher Hosseney

“…Purpose Oyster mushroom (Pleurotus ostreatus) is becoming more popular as an efficient biotechnological procedure for upcycling agricultural by-products into valuable human food. This study looked into the possibility of employing banana residue (BR) and sorghum stalks (SS) as localized feasible rice straw (RS) substitutes for cultivating P. ostreatus. …”
Get full text

A Review of the Progress in the Development of Leishmaniasis Vaccines by Narges Khaghanzadeh, Fatemeh Javadi, Afshin Samiei

“…Additionally, the mutant gene-centered LmCen-/- vaccine has completed Phase 1 clinical trials in humans. Given the importance of developing a leishmaniasis vaccine, research in this area continues. …”
Get full text

Patient Experience (PX) Giants: Pioneers and the Path Forward by Geoffrey Silvera, Courtney Haun, Varun Natarajan

“…The digital transformation in healthcare, while promising improved access and personalization, poses potential risks to patient-centeredness, necessitating vigilance in maintaining empathetic, human-centered care. Additionally, ensuring equitable PX across fragmented systems requires culturally competent and accessible care models. …”
Get full text

Polysaccharides of St. John’s Wort Herb Stimulate NHDF Proliferation and NEHK Differentiation via Influence on Extracellular Structures and Signal Pathways by S. Abakuks, A. M. Deters

“…Biological activity on human skin keratinocytes and fibroblasts was assessed by investigation of their effect on proliferation, metabolism, cytotoxicity, apoptosis and differentiation. …”
Get full text

Highly Sensitive Amperometric α-Ketoglutarate Biosensor Based on Reduced Graphene Oxide-Gold Nanocomposites by Gang Peng, Yadong Yu, Xiaojun Chen, He Huang

“…Moreover, the prepared GLUD/rGO-Aunano/GCE was further evaluated to be highly selective and used to test α-KG in human serum samples. The recovery and the RSD values were calculated in the range of 97.9–102.4% and 3.8–4.5%, respectively, showing a great prospect for its real application.…”
Get full text

Evaluation of Staining Reduction of Teeth Endodontically Treated with CTZ Paste through the Use of Polytetrafluoroethylene Isolation Tape by Lucas de Lima Oliveira Barbosa, Jaine Viviane Silva, Leopoldo Cosme-Silva, Daniela Maria Carvalho Pugliesi, Patrícia Batista Lopes do Nascimento, Dayse Andrade Romão, Priscylla Gonçalves Correia Leite de Marcelos, Daniel Pinto de Oliveira, Valdeci Elias dos Santos Junior

“…Material and Methods: 50 human deciduous incisors were selected. The teeth received CTZ filling and were divided according to whether or not PTFE was used, as well as by the length of the remaining root (1/3 or 2/3 of the root) and by the restorative material (Modified Resin Glass Ionomer Cement or Opus Bulk Resin Fill Flow). …”
Get full text