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Microarray Profiling of Lymphocytes in Internal Diseases With an Altered Immune Response: Potential and Methodology
Published 2005-01-01“…Lymphocytes express more than 75% of the human genome, and, being an important part of the immune system, they play a central role in the pathogenesis of asthma, RA, and SLE. …”
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143
Why Rights are Wrong in ASEAN and Beyond: A Critique of the Foundations of Universal Human Rights
Published 2020-05-01“…Part Two then examines whether the original axiomatic listing of human rights or an iteration of human rights founded upon the human genome or a Kantian underpinning can legitimise human rights and, if not, whether reference to the human soul made in the image of God with its natural law may substantiate the human rights project, perhaps, articulated as congruent with the purpose and design courts now recognise in the natural laws found in every ecosystem of nature. …”
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144
Effects of Single Nucleotide Polymorphism Marker Density on Haplotype Block Partition
Published 2016-12-01“…Many researchers have found that one of the most important characteristics of the structure of linkage disequilibrium is that the human genome can be divided into non-overlapping block partitions in which only a small number of haplotypes are observed. …”
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145
Study of Modern Human Evolution via Comparative Analysis with the Neanderthal Genome
Published 2013-12-01“…It has always been considered fascinating to compare the modern human genome with that of archaic humans to identify modern human-specific sequence variants and figure out those that made modern humans different from their predecessors or cousin species. …”
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146
Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence
Published 2024-12-01“…They make up roughly 8% of the human genome. HERVs exhibit many physiological and non-physiological functions; for example, they play a role in the development of many diseases. …”
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147
Quantifying the regulatory potential of genetic variants via a hybrid sequence-oriented model with SVEN
Published 2024-12-01“…We expect that SVEN will enable more effective in silico analysis and interpretation of human genome-wide disease-related genetic variants.…”
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148
ParSite is a multicolor DNA labeling system that allows for simultaneous imaging of triple genomic loci in living cells.
Published 2025-01-01“…The organization of the human genome in space and time is critical for transcriptional regulation and cell fate determination. …”
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149
Just a SNP away: The future of in vivo massively parallel reporter assay
Published 2025-02-01“…The human genome is largely noncoding, yet the field is still grasping to understand how noncoding variants impact transcription and contribute to disease etiology. …”
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150
Mechanism of Repeat-Associated MicroRNAs in Fragile X Syndrome
Published 2012-01-01“…The majority of the human genome is comprised of non-coding DNA, which frequently contains redundant microsatellite-like trinucleotide repeats. …”
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151
Enhancing computational accuracy with parallel parameter optimization in variational quantum eigensolver
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152
Clinical Manifestations of Hemochromatosis in HFE C282Y Homozygotes Identified by Screening
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153
Gene Expression Changes in Venous Segment of Overflow Arteriovenous Fistula
Published 2013-01-01“…Total RNA was extracted from the venous tissue samples, and gene expression between the 2 groups was compared using Whole Human Genome DNA microarray 44 K. Microarray data were analyzed by GeneSpring GX software and Ingenuity Pathway Analysis. …”
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154
Emotions as Self-Organizational Factors of Anthropogenesis, Noogenesis and Sociogenesis
Published 2021-06-01“…Emotions self-organize the process of anthropologisation of life, which is possible based on the synergy of human genome, biochemical, physiological phenomena and instincts. …”
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155
Applied of bioinformatics in drug discovery and drug development: Bioinformatic analysis 1996-2024
Published 2024-01-01“…Advance science of medicine after human genome project were established accelerating the development of new field called bionformatics. …”
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156
Screening for Iron Overload: Lessons from the HEmochromatosis and IRon Overload Screening (HEIRS) Study
Published 2009-01-01Get full text
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157
Mining the Proteome of subsp. ATCC 25586 for Potential Therapeutics Discovery: An Approach
Published 2016-12-01“…Our study divulged 1,499 proteins of F. nucleatum, which have no homolog's in human genome. These proteins were subjected to screening further by using the Database of Essential Genes (DEG) that resulted in the identification of 32 vitally important proteins for the bacterium. …”
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158
A walk through the development of human leukocyte antigen typing: from serologic techniques to next-generation sequencing
Published 2024-12-01“…Given that the MHC represents the most polymorphic region in the human genome, HLA typing is crucial in organ transplantation. …”
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159
Inference Attacks on Genomic Data Based on Probabilistic Graphical Models
Published 2020-09-01“…The rapid progress and plummeting costs of human-genome sequencing enable the availability of large amount of personal biomedical information, leading to one of the most important concerns — genomic data privacy. …”
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Adaptive Evolution Coupled with Retrotransposon Exaptation Allowed for the Generation of a Human-Protein-Specific Coding Gene That Promotes Cancer Cell Proliferation and Metastasis...
Published 2015-01-01“…Till date whether human genome includes species-specific cancer-related genes that could potentially contribute to a higher cancer susceptibility remains obscure. …”
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