When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells by Fuquan Chen, Jiaojiao Ji, Jian Shen, Xinyi Lu

“…Most of the human genome can be transcribed into RNAs, but only a minority of these regions produce protein-coding mRNAs whereas the remaining regions are transcribed into noncoding RNAs. …”
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Molecular profiling and detection methods of microRNA in cancer research by Nurul-Syakima Ab Mutalib, Imilia Ismail, Hooi-Leng Ser

“… A large portion of human genome was believed to be “useless” and termed as “junk DNA” in the past, given that these sequences did not have any protein coding role. …”
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Interspecies In Vitro Evaluation of Stereoselective Protein Binding for 3,4-Methylenedioxymethamphetamine by Wan Raihana Wan Aasim, Soo Choon Tan, Siew Hua Gan

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Drosophila melanogaster as an alternative animal model in fat metabolism studies by Dilan de Silva, Mangala Gunatilake

“…It serves as one of the best alternative model organisms as it comprises most genes related to metabolism which are conserved in the human genome. The simplicity in genetics as well as their rapid life cycle makes it a righteous model organism that can be efficiently utilized in research. …”
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Brief Overview of a Decade of Genome-Wide Association Studies on Primary Hypertension by Afifah Binti Azam, Elena Aisha Binti Azizan

“…GWASs work through revealing links between DNA sequence variation and a disease or trait with biomedical importance. The human genome is a very long DNA sequence which consists of billions of nucleotides arranged in a unique way. …”
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Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy by Carla Sanjurjo-Soriano, Vasiliki Kalatzis

“…New advances in the field of genome editing using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein (Cas) have provided an accurate and efficient way to edit the human genome and represent an appealing alternative for treating IRDs. …”
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Human-Specific Endogenous Retroviruses by Anton Buzdin

“…Although modest in terms of its copy number, this group appeared to modify the human genome activity by endogenizing ~50 functional copies of viral genes that may have important implications in the immune response, cancer progression, and antiretroviral host defense. …”
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Next-Generation Sequencing and Epigenomics Research: A Hammer in Search of Nails by Shrutii Sarda, Sridhar Hannenhalli

“…After the initial enthusiasm of the human genome project, it became clear that without additional data pertaining to the epigenome, i.e., how the genome is marked at specific developmental periods, in different tissues, as well as across individuals and species-the promise of the genome sequencing project in understanding biology cannot be fulfilled. …”
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The distribution of allele frequencies of the 15 Short Tandem Repeats loci in Elazığ population, Turkiye by Aziz Aksoy, Mehmet Tokdemi̇r, Vahit Konar

“…The DNA within the Human Genome involves loci with high polymorphism such as short tandem repeats (STR). …”
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Genome Architecture and Its Roles in Human Copy Number Variation by Lu Chen, Weichen Zhou, Ling Zhang, Feng Zhang

“…Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs), are being increasingly discovered as a genetic source of human diversity and the pathogenic factors of diseases. …”
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Nutrigenomics: Definitions and Advances of This New Science by N. M. R. Sales, P. B. Pelegrini, M. C. Goersch

“…With the advance of science, especially after the conclusion of the Human Genome Project (HGP), scientists started questioning if the interaction between genes and food bioactive compounds could positively or negatively influence an individual’s health. …”
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Role of Gene Length in Control of Human Gene Expression: Chromosome-Specific and Tissue-Specific Effects by Jay C. Brown

“…This study was carried out to pursue the observation that the level of gene expression is affected by gene length in the human genome. As transcription is a time-dependent process, it is expected that gene expression will be inversely related to gene length, and this is found to be the case. …”
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Melittin, a Potential Natural Toxin of Crude Bee Venom: Probable Future Arsenal in the Treatment of Diabetes Mellitus by Md. Sakib Hossen, Siew Hua Gan, Md. Ibrahim Khalil

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Genetic Vectors as a Tool in Association Studies: Definitions and Application for Study of Rheumatoid Arthritis by Igor Sandalov, Leonid Padyukov

“…To identify putative relations between different genetic factors in the human genome in the development of common complex disease, we mapped the genetic data to an ensemble of spin chains and analysed the data as a quantum system. …”
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Synthesis, Structure, and Anticancerous Properties of Silver Complexes by Shraddha Shukla, A. P. Mishra

“…The completion of the human genome sequence and its subsequent improvements in the sequence data are important steps to fully comprehend cancer cell biology. …”
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The Theranostic Genome by Xiaoying Xu, Pablo Jané, Vincent Taelman, Eduardo Jané, Rebecca A. Dumont, Yonathan Garama, Francisco Kim, María del Val Gómez, Karim Gariani, Martin A. Walter

“…To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be utilized to combine therapeutic and diagnostic applications. …”
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Heterogeneity of Genetic Landscapes in Salivary Gland Tumors and Their Critical Roles in Current Management by Anam YOUSAF, Sarina SULONG, Baharudin ABDULLAH, Norhafiza Mat LAZIM

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Homo Sapiens Chromosomal Location Ontology: A Framework for Genomic Data in Biomedical Knowledge Graphs by Taha Mohseni Ahooyi, Benjamin Stear, J. Alan Simmons, Christopher M. Nemarich, Jonathan C. Silverstein, Deanne M. Taylor

“…Abstract The Homo sapiens Chromosomal Location Ontology (HSCLO) is designed to facilitate the integration of human genomic features into biomedical knowledge graphs from releases GRCh37 and GRCh38 at multiple resolutions. …”
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Differential expression of plasma extracellular vesicle miRNAs as biomarkers for distinguishing psoriatic arthritis from psoriasis by Kexiang Yan, Jie Zhu, Mengmeng Zhang, Fuxin Zhang, Bing Wang, Ling Han, Qiong Huang, Yulong Tang, Yuan Li, Nikhil Yawalkar, Zhenghua Zhang, Zhenmin Niu, Xiangxiang Pan

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Genetics and Molecular Biology of Epstein-Barr Virus-Encoded BART MicroRNA: A Paradigm for Viral Modulation of Host Immune Response Genes and Genome Stability by David H. Dreyfus

“…Viral-encoded microRNA and viral mRNA transferred to bystander cells through vesicles, defective viral particles, or other mechanisms suggest a new paradigm in which bystander or hit-and-run mechanisms enable the virus to transiently or chronically alter human immune response genes as well as the stability of the human genome.…”
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