Suggested Topics within your search.
Suggested Topics within your search.
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Endothelial Progenitors as Tools to Study Vascular Disease
Published 2012-01-01“…However, EPCs also have an additional research value in vascular disease modelling to interrogate human disease mechanisms. The term EPC is used to describe a diverse variety of cells, and we have identified a specific EPC subtype called outgrowth endothelial cell (OEC) as the best candidate for vascular disease modelling because of its high-proliferative potential and unambiguous endothelial commitment. …”
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62
PLAGUE THE HIDDEN OLD NEMESIS
Published 2024-10-01“…It represents a typical example of the evolution of human disease from an infection, originally confined to wild animals. …”
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63
Update in Small Bowel Physiology: Part 2
Published 1990-01-01“…The recent advances in clinically important diseases of the small intestine have been reviewed however, the basis for many of these clinical advances rests with important observations on alterations in the physiology of the small intestine, as well as mechanistic observations of alterations in small 1nrestinal function in models of human disease. In this review a summary of the past year's literature is presented which will draw attention to the considerable progress in small bowel physiology which will soon be translated into an improved understanding of the pathophysiology of a variety of intestinal disorders.…”
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Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening
Published 2022-01-01“…Clinical trials serve as the fundamental prerequisite for clinical therapy of human disease, which is primarily based on biomedical studies in animal models. …”
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66
Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate
Published 2004-01-01“…BACKGROUND: The role of reoviruses in human disease is uncertain. Most identified cases are sporadic and asymptomatic or produce minor upper respiratory or gastrointestinal symptoms. …”
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67
Blood Feeding Insect Series: Yellow Fever
Published 2007-03-01“…Smartt, describes this feared human disease transmitted through the bite of infected mosquitoes, which even today poses formidable challenges and dangers to humans around the world. …”
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La Fiebre Amarilla
Published 2007-04-01“…It describes this feared human disease transmitted through the bite of infected mosquitoes, which even today poses formidable challenges and dangers to humans around the world. …”
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69
La Fiebre Amarilla
Published 2007-04-01“…It describes this feared human disease transmitted through the bite of infected mosquitoes, which even today poses formidable challenges and dangers to humans around the world. …”
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Cyclin-dependent protein kinases and cell cycle regulation in biology and disease
Published 2025-01-01“…We then discuss the potential roles and deregulation of CDKs in human pathologies, with a particular focus on cancer, the human disease in which CDKs have been most extensively studied and explored as therapeutic targets. …”
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72
Epidemiology of Lyme Disease
Published 1991-01-01“…Investigation of the epidemiology of Lyme disease depends upon information generated from several sources. Human disease surveillance can be conducted by both passive and active means involving physicians, public health agencies and laboratories. …”
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73
Blood Feeding Insect Series: Yellow Fever
Published 2007-03-01“…Smartt, describes this feared human disease transmitted through the bite of infected mosquitoes, which even today poses formidable challenges and dangers to humans around the world. …”
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74
Vector-borne Rickettsia Pathogens
Published 2024-04-01“…This publication summarizes the human-disease-causing pathogens in the genus Rickettsia in the United States and delivers general knowledge of their vectors and the diseases they cause. …”
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75
Oxidative Stress and Inflammation in Heart Disease: Do Antioxidants Have a Role in Treatment and/or Prevention?
Published 2011-01-01“…Inflammation triggered by oxidative stress is the cause of much, perhaps even most, chronic human disease including human aging. The oxidative stress originates mainly in mitochondria from reactive oxygen and reactive nitrogen species (ROS/RNS) and can be identified in most of the key steps in the pathophysiology of atherosclerosis and the consequential clinical manifestations of cardiovascular disease. …”
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76
Human Polyomavirus Reactivation: Disease Pathogenesis and Treatment Approaches
Published 2013-01-01“…The recent discoveries of eight new members of the Polyomaviridae family that are capable of infecting humans suggest that there are more to be discovered and raise the possibility that they may play a more significant role in human disease than previously understood. In spite of this, there remains a dearth of specific therapeutic options for human polyomavirus infections and an incomplete understanding of the relationship between the virus and the host immune system. …”
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77
Microbiology /
Published 2005Table of Contents: “…The history and scope of microbiology -- The study of microbial structure: microscopy and specimen preparation -- Procaryotic cell structure and function -- Eucaryotic cell structure and function -- Microbial nutrition -- Microbial growth -- Control of microorganisms by physical and chemical agents -- Metabolism: energy, enzymes, and regulation -- Metabolism: energy release and conservation -- Metabolism: the use of energy in biosynthesis -- Genes: structure, replication, and mutation -- Genes: expression and regulation -- Microbial recombination and plasmids -- Recombinant DNA technology -- Microbial Genomics -- The viruses: introduction and general characteristics -- The viruses: bacteriophages -- The viruses: viruses of eucaryotes -- Microbial taxonomy -- The archaea -- Bacteria: the deinococci and nonproteobacteria gram negatives -- Bacteria: the proteobacteria -- Bacteria: the Low G 1 C gram positives -- Bacteria: the High G 1 C gram positivies -- The fungi (eumycota), slime molds, and water molds -- The algae -- The protozoa -- Microorganism interactions and microbial ecology -- Microorganisms in aquatic environments -- Microorganisms in terrestrial environments -- Normal microbiota and nonspecific host resistance -- Specific immunity -- Medical immunology -- Pathogenicity of microorganisms -- Antimicrobial chemotherapy -- Clinical microbiology -- The epidemiology of infectious disease -- Human diseases caused by viruses -- Human diseases caused by bacteria -- Human diseases causedd by fungi and protozoa -- Microbiology of food -- Industrial microbiology and biotechnology.…”
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78
Decoding mitochondrial DNA damage and repair associated with H. pylori infection
Published 2025-01-01“…Bacterial infection significantly increases oxidative stress, driving mitochondrial genomic instability and initiating inflammatory human disease. Oxidative DNA base damage is predominantly repaired by base excision repair (BER) in the nucleus (nBER) as well as in the mitochondria (mtBER). …”
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Assessing live microbial therapeutic transmission
Published 2025-12-01“…The development of fecal microbiota transplantation and defined live biotherapeutic products for the treatment of human disease has been an empirically driven process yielding a notable success of approved drugs for the treatment of recurrent Clostridioides difficile infection. …”
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Tofersen and other antisense oligonucleotides in ALS
Published 2025-01-01“…The results of treatment with the ASO tofersen in SOD1-ALS show that the drug has a convincing beneficial effect on ALS caused by SOD1 mutations, that preclinical studies in rodents predicted the therapeutic effect in the human disease, and that clinical efficacy is associated with a specific sequence of effects of the drug on mechanistic and degenerative biomarkers and, subsequently, functional outcomes such as weight stabilization and ALSFRS-R. …”
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