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  1. 19481

    The Role of SGLT2 Inhibitor on the Treatment of Diabetic Retinopathy by Wenjun Sha, Song Wen, Lin Chen, Bilin Xu, Tao Lei, Ligang Zhou

    Published 2020-01-01
    “…Recent studies have found that SGLT2 is also expressed in the human retina. Now, the prevention and treatment of diabetic retinopathy with SGLT2i while reducing blood sugar has become a new research field. …”
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  2. 19482
  3. 19483

    CHEMOTYPE VERBOCCIDENTAFURAN IN Baccharis punctulata (Asteraceae): FURANIC SESQUITERPENES CORRELATION AND MOLECULAR DOCKING INTO THE BENZODIAZEPINE RECEPTOR by Jociani Ascari, Murilo S. de Oliveira, André L. Rüdiger, Elaine Elisabetsky, Domingos S. Nunes, Jorge Iulek, Dilamara R. Scharf, Gustavo Heiden

    Published 2025-01-01
    “…Considering the occurrence and availability of 1 in the species B. punctulata and its structural similarity to compound 2, docking calculations were performed for the interaction of both compounds with the human a1-ß2-y2 GABAA receptor. The results suggest that both compounds 1 and 2 must have affinity for the cavity at a1-y2 interface and support the development of pharmacological research on the compound verboccidentafuran 1 as a drug candidate for modulating the GABA/benzodiazepine complex in the central nervous system.…”
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  4. 19484

    Embracing generative artificial intelligence: The perspectives of English instructors in Thai higher education institutions by Lucas Kohnke, Mark B. Ulla

    Published 2024-12-01
    “…The participants emphasised that human instructors were still needed, although their roles needed to evolve. …”
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  5. 19485

    Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations by Helena W.C. Hofland, Edris W. Kalanzi, Emmie Viyuyi, Tilinde Chokotho, Titus M. Opegu, Eduard E. Zijlstra

    Published 2025-01-01
    “…World-wide, burns are most common in low resource settings (LRS) with high mortality. Human resources, equipment and affordable, effective and safe treatments all influence outcome. …”
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  6. 19486

    HHV8-Negative Primary Effusion Lymphoma of B-Cell Lineage: Two Cases and a Comprehensive Review of the Literature by Neeraj Saini, Ephraim P. Hochberg, Erica A. Linden, Smita Jha, Heinz K. Grohs, Aliyah R. Sohani

    Published 2013-01-01
    “…The neoplastic lymphoid cells are frequently infected with human herpes virus 8 (HHV8), also known as Kaposi sarcoma herpes virus (KSHV). …”
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  7. 19487

    Limitations on the Detection Rate of High-Risk HPV by Hybrid Capture 2 Methodology in High Grade Intraepithelial (HSIL) or Atypical Squamous Cells-Cannot Exclude HSIL (ASC-H) Cytol... by Jean-Christophe Noël, Philippe Simon

    Published 2015-01-01
    “…Recent literature data suggest that the high-risk human papillomaviruses (HR-HPVs) testing with several molecular techniques could be an alternative to cytology in the detection of cervical intraepithelial neoplasias of grade 2 or worse (CIN2+). …”
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  8. 19488

    Por una economía orientada hacia la reproducción de la vida by Franz J. Hinkelammert, Henry Mora Jiménez

    Published 2009-01-01
    “…This rationality is not based on the preferences of the consumer, but on people's needs; not on economic calculations but on the ethics of the common good that enable the conservation and reproduction of the natural cycle of human and natural life. This article suggests that in order to attain this rationality, a criticism of the logic of empirical fetishism is necessary; so too, is a critique of our understanding of reality constituted entirely by market relations. …”
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  9. 19489

    Reverent Induction: Epistemology and the Romantic Education of the Child Reader in Charles Kingsley’s The Water-Babies (1863) by Laura H. Clarke

    Published 2020-12-01
    “…Like the Romantics, Kingsley believed that the wonder and imagination of childhood were essential for fostering what he called ‘reverent induction’—the ability to see in each process of inductive reasoning the unfolding of God’s plan for human perception. Kingsley’s praise of inductive reason in contrast to deductive reason, and the influence of Romantic philosophical ideas on his work, provides an entirely new interpretive framework for understanding the role of the narrator in The Water-Babies and his conversation with the child reader. …”
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  10. 19490

    A Technique: Examining the Evidence by Serkan AKKOYUNLU, Mehmet Hakan TÜRKÇAPAR

    Published 2012-12-01
    “…Introduction: Cognitive therapy is based on the realistic epistemology which exerts that there is an objective reality beyond human experience. Cognitive models of psychopathology stipulate that the processing of external event or internal stimuli is biased and therefore systematically distorts the individual’s construction of his or her experiences, leading to a variety of cognitive errors. …”
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  11. 19491

    Personality and Motives for Self-Employment by Abu H. Ayob, Hazrul Izuan Shahiri, Hamizah Abd Hamid, Wan Kamal Mujani

    Published 2024-12-01
    “…Abstract: Introduction: Personality is one of the dominant intrinsic determinants in understanding human behavior, including the economic actors. Although considerable research has examined the typical characteristics of entrepreneurs, scholars have mostly neglected the binary motives for self-employment. …”
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  12. 19492

    Application of Minimax Optimization Mechanism in Chinese-English Machine Translation Quality Estimation by Xiaomei Zhang

    Published 2025-01-01
    “…Machine Translation Quality Estimation (MTQE) is pivotal in bridging the gap between machine-generated translations and human translation quality, especially in real-time applications where post-editing is not feasible. …”
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  13. 19493

    Aquaporin-2 in the early stages of the adenine-induced chronic kidney disease model. by Lucas H Oronel, Maria Ortiz, Carolina Yarza, Sofía Gayone, Carlos Davio, Mónica Majowicz, Maria Florencia Albertoni Borghese

    Published 2025-01-01
    “…The 0.25% adenine diet induces progressive kidney damage, constituting an adequate model mimicking human CKD. Vasopressin (VP) was postulated as a mediator of CKD, mainly acting through its V2 receptors. …”
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  14. 19494

    Induced pluripotent stem cell–related approaches to generate dopaminergic neurons for Parkinson’s disease by Ling-Xiao Yi, Hui Ren Woon, Genevieve Saw, Li Zeng, Eng King Tan, Zhi Dong Zhou

    Published 2025-11-01
    “…The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson’s disease, the second most common human neurodegenerative disease. Although the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson’s disease is still unclear, the advancement of stem cell approaches has shown promise for Parkinson’s disease research and therapy. …”
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  15. 19495

    Evaluation of the role of unconventional prefoldin RPB5 interactor (URI1) in hepatitis B virus infection by Karolína Štaflová, Aleš Zábranský, Iva Pichová

    Published 2025-01-01
    “…Although previous reports have suggested that URI1 may act as an HBV restriction factor, our results showed that URI1 silencing or overexpression did not affect HBV replication in HepG2-NTCP cells. In primary human hepatocytes, URI1 knockdown modestly reduced HBV markers but did not significantly alter acute infection. …”
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  16. 19496
  17. 19497

    An IoT and Machine Learning-Based Model to Monitor Perishable Food towards Improving Food Safety and Quality by Amina Batool, Souvik Ganguli, Hashem Ali Almashaqbeh, Muhammad Shafiq, A. L. Vallikannu, K. Sakthidasan Sankaran, Samrat Ray, F. Sammy

    Published 2022-01-01
    “…Additionally, it safeguards food imported from other nations by confirming that it is safe for human consumption before it is released. This article describes a technique for monitoring perishable goods that is based on the Internet of Things and machine learning. …”
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  18. 19498

    Geomorphology of the Caracota Valley, Western Altiplano, Northern Chile by Jan-Christoph Otto, Matias Gallardo, Luca Sitzia, Daniela Osorio, Eugenia M. Gayo

    Published 2024-12-01
    “…The geomorphological study is embedded into a geoarchaeological research project on early human occupation in the zone of the Salar de Surire, Northern Chile, at 18°50′S. …”
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  19. 19499

    A Book Review of MOOCs Design, Application and Business Models by Mohammad Ali Rostaminezhad

    Published 2020-12-01
    “…In line with critical reviewing, in addition to using the framework introduced in the “Human Sciences Book Review Questionnaire”, evaluation criteria for academic books have also been used. …”
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  20. 19500

    A pressure model of immune response to mycobacteriumtuberculosis infection in several space dimensions by Fabrizio Clarelli, Roberto Natalini

    Published 2010-03-01
    “…However, in general, the human immune system is able to contain it. In this work, we propose a mathematical model which describes the early immune response to the Mtb infection in the lungs, also including the possible evolution of the infection in the formation of a granuloma. …”
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