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19481
The Role of SGLT2 Inhibitor on the Treatment of Diabetic Retinopathy
Published 2020-01-01“…Recent studies have found that SGLT2 is also expressed in the human retina. Now, the prevention and treatment of diabetic retinopathy with SGLT2i while reducing blood sugar has become a new research field. …”
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19482
Effect of Tapuy (Philippine Rice Wine) Lees on the Gut Microbiota Profile and Lifespan under Normal and Stress Conditions in Drosophila melanogaster
Published 2024-12-01“…Further studies are recommended to evaluate their potential benefits for human health.…”
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19483
CHEMOTYPE VERBOCCIDENTAFURAN IN Baccharis punctulata (Asteraceae): FURANIC SESQUITERPENES CORRELATION AND MOLECULAR DOCKING INTO THE BENZODIAZEPINE RECEPTOR
Published 2025-01-01“…Considering the occurrence and availability of 1 in the species B. punctulata and its structural similarity to compound 2, docking calculations were performed for the interaction of both compounds with the human a1-ß2-y2 GABAA receptor. The results suggest that both compounds 1 and 2 must have affinity for the cavity at a1-y2 interface and support the development of pharmacological research on the compound verboccidentafuran 1 as a drug candidate for modulating the GABA/benzodiazepine complex in the central nervous system.…”
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19484
Embracing generative artificial intelligence: The perspectives of English instructors in Thai higher education institutions
Published 2024-12-01“…The participants emphasised that human instructors were still needed, although their roles needed to evolve. …”
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19485
Increasing experience in the use of papaya for burn injuries in an African context, potential and limitations
Published 2025-01-01“…World-wide, burns are most common in low resource settings (LRS) with high mortality. Human resources, equipment and affordable, effective and safe treatments all influence outcome. …”
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19486
HHV8-Negative Primary Effusion Lymphoma of B-Cell Lineage: Two Cases and a Comprehensive Review of the Literature
Published 2013-01-01“…The neoplastic lymphoid cells are frequently infected with human herpes virus 8 (HHV8), also known as Kaposi sarcoma herpes virus (KSHV). …”
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19487
Limitations on the Detection Rate of High-Risk HPV by Hybrid Capture 2 Methodology in High Grade Intraepithelial (HSIL) or Atypical Squamous Cells-Cannot Exclude HSIL (ASC-H) Cytol...
Published 2015-01-01“…Recent literature data suggest that the high-risk human papillomaviruses (HR-HPVs) testing with several molecular techniques could be an alternative to cytology in the detection of cervical intraepithelial neoplasias of grade 2 or worse (CIN2+). …”
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19488
Por una economía orientada hacia la reproducción de la vida
Published 2009-01-01“…This rationality is not based on the preferences of the consumer, but on people's needs; not on economic calculations but on the ethics of the common good that enable the conservation and reproduction of the natural cycle of human and natural life. This article suggests that in order to attain this rationality, a criticism of the logic of empirical fetishism is necessary; so too, is a critique of our understanding of reality constituted entirely by market relations. …”
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19489
Reverent Induction: Epistemology and the Romantic Education of the Child Reader in Charles Kingsley’s The Water-Babies (1863)
Published 2020-12-01“…Like the Romantics, Kingsley believed that the wonder and imagination of childhood were essential for fostering what he called ‘reverent induction’—the ability to see in each process of inductive reasoning the unfolding of God’s plan for human perception. Kingsley’s praise of inductive reason in contrast to deductive reason, and the influence of Romantic philosophical ideas on his work, provides an entirely new interpretive framework for understanding the role of the narrator in The Water-Babies and his conversation with the child reader. …”
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19490
A Technique: Examining the Evidence
Published 2012-12-01“…Introduction: Cognitive therapy is based on the realistic epistemology which exerts that there is an objective reality beyond human experience. Cognitive models of psychopathology stipulate that the processing of external event or internal stimuli is biased and therefore systematically distorts the individual’s construction of his or her experiences, leading to a variety of cognitive errors. …”
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19491
Personality and Motives for Self-Employment
Published 2024-12-01“…Abstract: Introduction: Personality is one of the dominant intrinsic determinants in understanding human behavior, including the economic actors. Although considerable research has examined the typical characteristics of entrepreneurs, scholars have mostly neglected the binary motives for self-employment. …”
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19492
Application of Minimax Optimization Mechanism in Chinese-English Machine Translation Quality Estimation
Published 2025-01-01“…Machine Translation Quality Estimation (MTQE) is pivotal in bridging the gap between machine-generated translations and human translation quality, especially in real-time applications where post-editing is not feasible. …”
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19493
Aquaporin-2 in the early stages of the adenine-induced chronic kidney disease model.
Published 2025-01-01“…The 0.25% adenine diet induces progressive kidney damage, constituting an adequate model mimicking human CKD. Vasopressin (VP) was postulated as a mediator of CKD, mainly acting through its V2 receptors. …”
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19494
Induced pluripotent stem cell–related approaches to generate dopaminergic neurons for Parkinson’s disease
Published 2025-11-01“…The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson’s disease, the second most common human neurodegenerative disease. Although the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson’s disease is still unclear, the advancement of stem cell approaches has shown promise for Parkinson’s disease research and therapy. …”
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19495
Evaluation of the role of unconventional prefoldin RPB5 interactor (URI1) in hepatitis B virus infection
Published 2025-01-01“…Although previous reports have suggested that URI1 may act as an HBV restriction factor, our results showed that URI1 silencing or overexpression did not affect HBV replication in HepG2-NTCP cells. In primary human hepatocytes, URI1 knockdown modestly reduced HBV markers but did not significantly alter acute infection. …”
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19496
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19497
An IoT and Machine Learning-Based Model to Monitor Perishable Food towards Improving Food Safety and Quality
Published 2022-01-01“…Additionally, it safeguards food imported from other nations by confirming that it is safe for human consumption before it is released. This article describes a technique for monitoring perishable goods that is based on the Internet of Things and machine learning. …”
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19498
Geomorphology of the Caracota Valley, Western Altiplano, Northern Chile
Published 2024-12-01“…The geomorphological study is embedded into a geoarchaeological research project on early human occupation in the zone of the Salar de Surire, Northern Chile, at 18°50′S. …”
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19499
A Book Review of MOOCs Design, Application and Business Models
Published 2020-12-01“…In line with critical reviewing, in addition to using the framework introduced in the “Human Sciences Book Review Questionnaire”, evaluation criteria for academic books have also been used. …”
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19500
A pressure model of immune response to mycobacteriumtuberculosis infection in several space dimensions
Published 2010-03-01“…However, in general, the human immune system is able to contain it. In this work, we propose a mathematical model which describes the early immune response to the Mtb infection in the lungs, also including the possible evolution of the infection in the formation of a granuloma. …”
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