Moving from an “anti-aging” paradigm toward the concept of “disease-free aging”: the role of senolytics in modern medicine by Ivan Aprahamian, Andréia Pain, Virgílio Garcia Moreira

“…Senolytic therapy requires strong evidence in human trials, and dasatinib and quercetin have shown good results in phase II trials with idiopathic pulmonary fibrosis and diabetic renal disease. …”
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Potential Association of the Oral Microbiome with Trimethylamine N-Oxide Quantification in Mexican Patients with Myocardial Infarction by Paulina Hernández-Ruiz, Alma R. Escalona Montaño, Luis M. Amezcua-Guerra, Héctor González-Pacheco, Elena Niccolai, Amedeo Amedei, María M. Aguirre-García

“…In the present pilot study, the involvement of oral dysbiosis related to the presence of TMAO has been considered an independent component of the standard risk factors (SRs) in the development of MI, which has not been previously described in human cohorts. A positive and significant correlation of TMAO levels with Porphyromonas was identified; likewise, the increase of the genus Peptidiphaga in patients without SRs was observed. …”
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Xylanase-Producing Microbes and Their Real-World Application by Milan Phuyal, Uttam Budhathoki, Durga Bista, Shailendra Shakya, Rajan Shrestha, Ashwinee Kumar Shrestha

“…The objective of this review article is to compile microbial sources of this enzyme and its application for betterment of human kind.…”
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Kårebolssätern and other shielings - the emergence and development of Swedish transhumant pastoralism by Eva Svensson, Susanne Pettersson, Annie Johansson

“…The study utilized various methodologies, including pollen analysis, archaeological mapping, and historical documentation, to trace human impact and land use, indicating shifts between grazing and cereal cultivation. …”
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Acefylline Derivatives as a New Class of Anticancer Agents: Synthesis, Molecular Docking, and Anticancer, Hemolytic, and Thrombolytic Activities of Acefylline-Triazole Hybrids by Irum Shahzadi, Ameer Fawad Zahoor, Bushra Parveen, Azhar Rasul, Zohaib Raza, Sajjad Ahmad, Ali Irfan, Gamal A. El-Hiti

“…The synthesized acefyllines demonstrated moderate activity (cell viability = 22.55 ± 0.95% − 57.63 ± 3.65%) compared with the starting drug acefylline (cell viability = 80 ± 3.87%) against the human liver carcinoma (Hep G2 cell line). N-(4-Chlorophenyl)-2-(4-(3,4-dichlorophenyl)-5-((1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)methyl)-4H-1,2,4-triazol-3-ylthio)acetamide exhibited the most potent activity (cell viability = 22.55 ± 0.95%) among the synthesized derivatives. …”
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Gene Technology for Papaya Ringspot Virus Disease Management by Md. Abul Kalam Azad, Latifah Amin, Nik Marzuki Sidik

“…PRSV-resistant transgenic papaya is environmentally safe and has no harmful effects on human health. Recent studies have revealed that the success of adoption of transgenic papaya depends upon the application, it being a commercially viable product, bio-safety regulatory issues, trade regulations, and the wider social acceptance of the technology. …”
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Age Dependent Switching Role of Cyclin D1 in Breast Cancer by Carmela Rinaldi, Natalia Maria Malara, Rosalia D’Angelo, Antonina Sidoti, Attilio Leotta, Santo Lio, Basilio Caparello, Alessia Ruggeri, Vincenzo Mollace, Aldo Amato

“…Background: Cyclin D1 gene (CCND1) plays pivotal roles in the development of several human cancers, including breast cancer, functioning as an oncogene. …”
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Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Develop... by Elie El Agha, Saverio Bellusci

“…Basic research on embryonic lung development offers unique opportunities to make important discoveries that will impact human health. Developmental biologists interested in the molecular control of branching morphogenesis have intensively studied the developing lung, with its complex and seemingly stereotyped ramified structure. …”
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A multi-modal social media data analysis framework: Exploring the complex relationships among urban environment, public activity, and public perception—A case study of Xi’an, China... by Chuyi Guo, Yuchi Yang

“…Using Xi’an, China, as a typical case, it examines how public activities change over time and space, how they interact with urban spaces, as well as how different aspects of the built environment shape public perception.The main findings are as follows:(1) Public activity varies significantly across day and night, interacting in complex ways with urban spatial elements;(2) Public activity is driven by multiple interconnected factors;(3) The built environment affects public perception unevenly, with certain spatial elements evoking strong emotional resonance and reinforcing cultural identity;(4) A dynamic feedback loop exists between public activity and perception.This research offers novel insights into precision-oriented, human-centered, and sustainable urban development.…”
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Enoch Olujide Gbadegesin, Yunusa Kehinde Salami and Kola Abimbola (eds.) Exploring the Ethics of Individualism and Communitarianism. Harvest Day Publications ,2016,365p. by Adeshina Afolayan

“…While some confronted some basic elements of his work, like chapter four (human personality), seven (work), and nine (destiny), other chapters took the thematic concerns of, say, communitarianism and ethics as the springboard for further reflections on corruption, nationalism and nation building, citizenship, religion, personhood, leadership, race, justice, gender and the nature of African philosophy. …”
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PREVENTION OF INFERIORITY COMPLEX ATTITUDES ACCORDING TO THE QUR'AN by A Asnawiyah, Abd Wahid, Nurullah Amri, Muhammad Hadi Husni

“…The results of this study show that the mufassir emphasize that true strength lies in faith, solid faith is the initial key in overcoming the sense of inferiority complex, inferiority complex is the spiritual part of human beings and spiritual studies sourced from the Qur'an are the initial stages in fighting the inferiority complex. …”
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Application of Electrocoagulation Process Using Iron and Aluminum Electrodes for Fluoride Removal from Aqueous Environment by Edris Bazrafshan, Kamal Aldin Ownagh, Amir Hossein Mahvi

“…Fluoride in drinking water above permissible level is responsible for human being affected by skeletal fluorosis. The present study was carried out to assess the ability of electrocoagulation process with iron and aluminum electrodes in order to removal of fluoride from aqueous solutions. …”
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Climate change and migration dynamics in Somalia: a time series analysis of environmental displacement by Abdikadir Ahmed Mohamed, Ibtisam Mohamed Omar, Abdi Majid Yusuf Ibey, Mahdi Mohamed Omar

“…Climate change is a significant driver of human migration, especially in vulnerable regions like Somalia. …”
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Adsorption of chlorophenolic compounds on activated clinoptilolite by Mustafa Uçar

“…Concurrently, the occurring of phenolic compounds in aquatic ambit creates potential human health and environmental problems. There are a lot of technologies available for the treatment of organic pollutants. …”
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Sirtuin 1: A Dilemma in Transplantation by Sara Assadiasl, Nuala Mooney, Bahareh Mohebbi, Yousef Fatahi, Narjes Soleimanifar

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Colorimetric Detection of Ammonia Using Synthesized Silver Nanoparticles from Durian Fruit Shell by Eman Alzahrani

“…This enhances the application of the technique in human biomedical applications.…”
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Multi-resource constrained elective surgical scheduling with Nash equilibrium toward smart hospitals by Jun Xue, Zhi Li, Shuangli Zhang

“…Abstract This paper focuses on the elective surgical scheduling problem with multi-resource constraints, including material resources, such as operating rooms (ORs) and non-operating room (NOR) beds, and human resources (i.e., surgeons, anesthesiologists, and nurses). …”
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Kidney Stone Disease: An Update on Current Concepts by Tilahun Alelign, Beyene Petros

“…It is an increasing urological disorder of human health, affecting about 12% of the world population. …”
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Nutrient digestibility of fishmeal rations in primates by N. V. Gaponov, L. N. Gamko

“…Fishmeal is a feeding stuff, manufactured from fish, marine mammals, invertebrates not suitable for human consumption and by-products of their processing. …”
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In vitro model systems for host-microbiota interaction studies by R. Inciuraite, G. Varkalaite, J. Skieceviciene, J Skieceviciene, U. Kulokiene

“…Despite the efforts to explore the communication between the human gut and intestinal microbiota in recent years, the complexity of this interaction remains not fully understood. …”
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