Discriminative training of spiking neural networks organised in columns for stream‐based biometric authentication by Enrique Argones Rúa, Tim Vanhamme, Davy Preuveneers, Wouter Joosen

“…A network structure based on neuron columns is proposed, resembling cortical columns in the human cortex, and a new derivation of error backpropagation for the spiking neural networks that integrate the lateral inhibition in these structures. …”
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Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway. by Monica G Ferrini, Andrea Abraham, Revecca Millán, Leslie Graciano, Sriram V Eleswarapu, Jacob Rajfer

“…We hypothesized that COMP-4 may have a protective, stimulatory effect on the vascular endothelial cell. Human umbilical arterial endothelial cells were incubated for 24 hours with or without COMP-4 and, to replicate impairment of endothelial function, co-incubated with or without H2O2. …”
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Harnessing the AI/ML in Drug and Biological Products Discovery and Development: The Regulatory Perspective by Fahimeh Mirakhori, Sarfaraz K. Niazi

“…The term AI itself has become commonplace to argue that greater “human oversight” for “machine intelligence” is needed to harness the power of this revolutionary technology for both potential and risk management, and hence to call for more practical regulatory guidelines, harmonized frameworks, and effective policies to ensure safety, scalability, data privacy, and governance, transparency, and equitable treatment. …”
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Nail Biting as a Cause of Appendicitis by Michael Pagacz, Philip Bao, Juan Carlos Alvarez Moreno, Lydia Howard

“…Our case is an example of a rare scenario in which an Actinomyces-contaminated human nail lodged in the appendix of a woman eventually resulting in acute appendicitis.…”
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Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation by Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin Rittinger

“…Abstract Deubiquitinating enzymes (DUBs) are key regulators of cellular homoeostasis, and their dysregulation is associated with several human diseases. The ovarian tumour protease (OTU) family of DUBs are biochemically well-characterised and of therapeutic interest, yet only a few tool compounds exist to study their cellular function and therapeutic potential. …”
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Diversity and bioindicators of natural enemies in organic paddy fields implementing habitat modification by Setyadin Yuris, Leksono Amin Setyo, Tarno Hagus

“…Indonesian rice farming relies heavily on intensive systems, adversely affecting soil quality, human health, and non-target organisms. Organic systems are a viable alternative characterized by organic fertilizers and biopesticides, avoiding genetically modified microorganisms and promoting biodiversity. …”
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Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews by Cunping Yin, Yuan Liang, Jian Zhang, Guangping Ruan, Zian Li, Rongqing Pang, Xinghua Pan

“…In addition, the conditioned culture of human umbilical vein endothelial cells using medium collected from UC-MSCs showed higher expression of angiogenic markers and improved migration ability. …”
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Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells by Amanda C. Stacer, Hanxiao Wang, Joseph Fenner, Joseph S. Dosch, Anna Salomonnson, Kathryn E. Luker, Gary D. Luker, Alnawaz Rehemtulla, Brian D. Ross

“…We analyzed the activity of the proteasome, the primary organelle for targeted protein degradation, as a marker of tumor- and metastasis-initiating cells. Using human and mouse breast cancer cells expressing a validated fluorescent reporter, we found a small subpopulation of cells with low proteasome activity that divided asymmetrically to produce daughter cells with low or high proteasome activity. …”
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Biomonitoring of radioactive contamination using benthic invertebrate communities in Manzala Lake, Egypt by Imam Noha, Bendary Reda E.

“…Manzala Lake, the largest in Egypt’s Nile Delta, has significant human activity. The Lake’s ecological condition has recently been impacted by a significant increase in agricultural, industrial, and urban wastewater discharge. …”
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Nutrigenomics: Definitions and Advances of This New Science by N. M. R. Sales, P. B. Pelegrini, M. C. Goersch

“…Since ancient times, humans have known that environment and food can interfere with an individual’s health condition, and have used food and plants as medicines. …”
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Reimagining Christianity and Sexual Diversity in Africa by Ashwin Thyssen

“…This invitation is most clear: we are requested to re-imagine Africans who are LGBT+ as humans—fully human, and thus creatures of God. It is this invitation to which this review article responds. …”
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Optical and MRI Multimodal Tracing of Stem Cells In Vivo by Jia Yang, Min Yan, Zhong Wang, Cong Zhang, Miao Guan, Zhenglong Sun

“…This review provides an overview of various multimodal imaging technologies and labeling methods commonly used for tracing stem cells, including optical imaging, MRI, and the combination of the two, while explaining the principles involved, comparing the advantages and disadvantages of different combination schemes, and discussing the challenges and prospects of human stem cell tracking techniques.…”
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Bile Acids: Key Regulators and Novel Treatment Targets for Type 2 Diabetes by Yingjie Wu, An Zhou, Li Tang, Yuanyuan Lei, Bo Tang, Linjing Zhang

“…Type 2 diabetes mellitus (T2DM), characterized by insulin resistance and unclear pathogenesis, is a serious menace to human health. Bile acids are the end products of cholesterol catabolism and play an important role in maintaining cholesterol homeostasis. …”
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Safety Assessment of Ancient Buildings under Adjacent Subway Blasting Construction Based on the Optimized Fuzzy Optimal Method by Bo Wu, Pingting Liu, Wei Huang, Guowang Meng

“…Fragile ancient buildings are recognized as an eloquent testimony to human civilization, and their safety should arouse more attention. …”
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Artificial Intelligence Bias and the Amplification of Inequalities in the Labor Market by Matjaz Perc, H. Eren Suna, Mahmut Özer

“…We assess these threats by studying data from various labor fields, including justice, security, healthcare, human resource management, and education.…”
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Monitoring and Modelling the Trends of Primary and Secondary Air Pollution Precursors: The Case of the State of Kuwait by S. M. Al-Salem, A. R. Khan

“…Trends of pollutants and impact on human health have been studied and categorized based on recent literature. …”
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Gregorio de los Ríos at the Casa del Campo by Catherine Chomarat-Ruiz

“…Giving grace to the beauty of the nature given by God pagans and Christians would have understood this objective of an art which gives sense to human being. With Gregorio de los Ríos’ work, neglected by the historians, it is the Spanish influence on flower gardens, that we aim to question, from an aesthetical, political, scientific and metaphysical point of view.…”
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The Intersection of Global Legal Frameworks and Islamic Judicial Principles in Post-Conflict Reconstruction and Peace building by Suhaba Nizar Nazem, Ammar Khadim Jasim, Mohammed Turki, Oudha Yousif Salman Al-Musawi, Dmytro Khlaponin

“…The research aims to assess how these legal frameworks contribute to governance, human rights, and reconciliation in societies recovering from war. …”
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Recent Advances in Hydroxyapatite Scaffolds Containing Mesenchymal Stem Cells by John Michel, Matthew Penna, Juan Kochen, Herman Cheung

“…Further, in order to maintain a progressive scope of the field this review article will only focus on literature utilizing adult human derived MSCs (hMSCs) published in the last three years.…”
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Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization by Yi Zhang, Fu’an Ding, Junjie Han, Zongliang Wang, Wenjie Tian

“…The bladder is a dynamic organ located in the lower urinary tract, responsible for complex and important physiological activities in the human body, including collecting and storing urine. …”
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