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17721
Modeling the relationship between the moral charter derived from Islamic teachings and performance with the mediating variable of employees' perception
Published 2024-11-01“…He believed that the personal benefit of a human kind is the providence of God, not the will of the state. …”
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17722
Biofabrication of brain-like living tissue: structure to intelligence
Published 2025-01-01“…Brain, the material foundation of human intelligence, is the most complex tissue in the human body. …”
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17723
The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a...
Published 2025-01-01“…Data in three batches of human primary hepatocytes disclosed induction potential of Deg-AZM on CYP2B6 and CYP3A4.ConclusionThe in vivo metabolic pathway of Deg-AZM and in vitro possibility of drug interaction for Deg-AZM with CYP enzymes and drug transporter were fully investigated. …”
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17724
New Horizons In The Treatment Of Metastatic Castrate Resistant Prostate Cancer
Published 2023-06-01“…Just as a mechanic cannot repair a car without a thorough knowledge of its form, external and internal, a doctor cannot heal the human body without a deep understanding of its structure. …”
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17725
Anatomy In The Undergraduate Medical Curriculum; Blending The Old And New
Published 2023-04-01“…Just as a mechanic cannot repair a car without a thorough knowledge of its form, external and internal, a doctor cannot heal the human body without a deep understanding of its structure. …”
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17726
Development of a framework to structure decision-making in environmental and occupational health: A systematic review and Delphi study
Published 2025-01-01“…Background: Environmental and occupational health (EOH) assessments increasingly utilize systematic review methods and structured frameworks for evaluating evidence about the human health effects of exposures. However, there is no prevailing approach for how to integrate this evidence into decisions or recommendations. …”
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17727
Assessment of the Impact of Community-Based Tourism on the Economic, Social, and Cultural Empowerment of Women (Case Study: Coastal Villages of Bushehr Province)
Published 2024-06-01“…Consequently, development of human resource skills emerges as a critical component for progress and growth in rural communities. …”
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17728
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17729
VCP regulates early tau seed amplification via specific cofactors
Published 2025-01-01“…We used immortalized cells and human neurons to study the effects of VCP on tau seeding. …”
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17730
Analysis of Polycyclic Aromatic Hydrocarbon in Airborne Particulate Matter Samples by Gas Chromatography in Combination with Tandem Mass Spectrometry (GC-MS/MS)
Published 2021-01-01“…Polycyclic aromatic hydrocarbons (PAHs), the family of organic contaminations, have been shown to have negative effects on human health. However, until now, the comprehension on occurrence, distribution, and risk assessment of human exposure to PAHs has been limited in Vietnam. …”
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17731
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17732
The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies
Published 2025-01-01“…This increases the risk of human exposure to allergens as the plants and their parasitic fungi spread. …”
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17733
Mapping outcomes for recovery of consciousness in studies from 1986 to 2020: a scoping review protocol
Published 2022-06-01“…To support knowledge translation efforts, we will involve clinicians and researchers experienced in TBI care throughout the project from conceptualisation of the study through dissemination of results.Ethics and dissemination No ethical approval is required for this study as it is not determined to be human subjects research. Results will be presented at national conferences and published in peer-reviewed journals.Trial registration number CRD42017058383.…”
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17734
MAF1 inhibits hepatocarcinogenesis by fostering an immunostimulatory tumor microenvironment
Published 2025-01-01“…More importantly, we found that MAF1 not only enhances the intratumoral infiltration of CD8+ T cells by increasing CXCL10 secretion but also enhances their functional activity by inhibiting PDL1 transcription in mouse liver cancer, which were confirmed in human HCC or in vitro experiments. Furthermore, PDL1 overexpression accelerates mouse hepatocarcinogenesis by antagonizing the tumor-suppressive role of MAF1.Conclusions Our study uncovers a novel anti-tumor immunity of MAF1 in hepatocarcinogenesis and human HCC. …”
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17735
Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic...
Published 2025-01-01“…IntroductionThe risk of kidney fibrosis is significantly elevated in individuals with diabetes, chronic nephritis, trauma, and other underlying conditions. Concurrently, human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) and their extracellular vesicles (MSC-Exos) have gained prominence in regenerative medicine. …”
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17736
Analyzing Iran's Legislative Criminal Policy in Dealing with Environmental Terrorism, Emphasizing the Need for Criminalization and Preventive Measures
Published 2024-10-01“…Introduction: environmental security, is a necessary condition for the health and continuity of human life on earth and due to the vital, widespread and inevitable dependence of humans on the environment, if the environmental security is taken away and it is removed from the possibility of healthy living, as a result of the goal or the means of placing the environment, following environmental terrorism, with various methods such as polluting the natural and man-made environment with dangerous substances, extensive and irreparable damage is caused to human life and health And often, the most obvious effects of damage to the safety and health of the environment appear in the form of epidemics, and on the other hand, the cross-border effects of such actions and the possibility of transferring the said effects from through the flow of air or water or the carriers of disease agents to countries and regions beyond the place of the accident, and the possibility of spreading some of these effects on the life and health of future generations, reveals the seriousness of the danger of environmental terrorism, hence, The purpose of this thesis is to explain the vital necessity of legal, technical and specialized contrast, against environmental terrorism in the form of an efficient criminal policy with international interaction, with emphasizing the extent and irreparability of the effects caused by environmental terrorism, and the necessity and importance of preventive measures.Materials and Methods: In terms of the goal, the current research will cause expansion the legal theories and doctrine and complete the previous theories with the fundamental method of the research results, and also with the practical approach, effective practical solutions to deal with environmental terrorism will be presented, and on the other hand, the materials and information used in the research, They are collected with the library method and after collecting and categorizing the materials and information, with the descriptive-analytical method, the findings and the collected materials are analyzed logically and legally and they are used as the basis of citation to strengthen the approach of the researcher in the relevant subject.Results: In a comprehensive and efficient criminal policy to contrast against environmental terrorism, in addition to criminalizing this criminal phenomenon along with the real conceptology and in addition to recognizing its specific elements, it is expected that with the necessary criminal measures, specialized measures will be taken to identify and criminalize behaviors that it has a preliminary aspect to dangerous crimes, and it is possible that environmental terrorism is also committed through them, and therefore, in order to prevent this criminal phenomenon, criminalize such behaviors in the form of obstruction crimes seems necessary.Discussion: In Iran's criminal system, environmental terrorism has not been considered as an independent criminal behavior, with specific elements and specific conditions, However, due to the inherent of the behaviors related to environmental terrorism, this type of terrorism is inherently reprehensible, and as a rule, it can be included in various legal elements in the criminal laws, and on the other hand, due to the analogy of some elements of this criminal phenomenon with the destruction of the earth, According to jurisprudence, significant examples of environmental terrorism behaviors can be considered as examples of corruption in the land subject to Article 286 of the Islamic Penal Code (approved in 2012). …”
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17737
Generation of Insulin-Producing Cells from Canine Adipose Tissue-Derived Mesenchymal Stem Cells
Published 2020-01-01“…However, spheroid-like small clusters consisting of canine AT-MSCs and human recombinant peptide μ-pieces developed under a three-dimensional (3D) culture system were successfully differentiated into IPCs. …”
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17738
Cryo-EM structure of an activated GPR4–Gs signaling complex
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17739
ALKBH5, an m6A demethylase, attenuates tumor growth and inhibits metastasis in papillary thyroid carcinoma
Published 2025-01-01“…Additionally, ALKBH5 is associated with the development of numerous human cancers. However, it remains unclear whether ALKBH5 regulates the growth and metastasis of papillary thyroid carcinoma (PTC). …”
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17740
Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled...
Published 2025-01-01“…However, implementing DOT poses challenges for both patients and providers due to limited financial and human resources. Increasing evidence suggests that emerging digital adherence technologies, such as video directly observed therapy (VDOT), can serve as viable alternatives. …”
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